| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| O Milhavet, H E McMahon, W Rachidi, N Nishida, S Katamine, A Mangé, M Arlotto, D Casanova, J Riondel, A Favier, S Lehman. Prion infection impairs the cellular response to oxidative stress. Proceedings of the National Academy of Sciences of the United States of America. vol 97. issue 25. 2001-01-18. PMID:11095725. |
in addition, the infected cells presented an increased lipid peroxidation and signs of apoptosis associated with a dramatic reduction in the activities of the glutathione-dependent and superoxide dismutase antioxidant systems. |
2001-01-18 |
2023-08-12 |
Not clear |
| P R Holden, N H James, A N Brooks, R A Roberts, I Kimber, W D Penni. Identification of a possible association between carbon tetrachloride-induced hepatotoxicity and interleukin-8 expression. Journal of biochemical and molecular toxicology. vol 14. issue 5. 2000-12-22. PMID:10970000. |
the changes induced by these compounds can vary from gross alterations in dna repair mechanisms, protein synthesis, and apoptosis, to more discrete changes in oxidative damage and lipid peroxidation. |
2000-12-22 |
2023-08-12 |
human |
| M Poljak-Blazi, M Kralj, M P Hadzija, N Zarković, K Zarković, G Wae. Involvement of lipid peroxidation, oncogene expression and induction of apoptosis in the antitumorous activity of ferric-sorbitol-citrate. Cancer biotherapy & radiopharmaceuticals. vol 15. issue 3. 2000-12-06. PMID:10941536. |
involvement of lipid peroxidation, oncogene expression and induction of apoptosis in the antitumorous activity of ferric-sorbitol-citrate. |
2000-12-06 |
2023-08-12 |
human |
| Y C Fu, X P Jin, S M Wei, H F Lin, S Kace. Ultraviolet radiation and reactive oxygen generation as inducers of keratinocyte apoptosis: protective role of tea polyphenols. Journal of toxicology and environmental health. Part A. vol 61. issue 3. 2000-11-30. PMID:11036506. |
studies were thus undertaken to investigate the effects of uva or reactive oxygen species (ros) on lipid peroxidation, cell cycle, and apoptosis in primary cultured rat keratinocytes and to determine the possible protective effects of tea polyphenols (tpp). |
2000-11-30 |
2023-08-12 |
rat |
| Y C Fu, X P Jin, S M Wei, H F Lin, S Kace. Ultraviolet radiation and reactive oxygen generation as inducers of keratinocyte apoptosis: protective role of tea polyphenols. Journal of toxicology and environmental health. Part A. vol 61. issue 3. 2000-11-30. PMID:11036506. |
in summary, these data demonstrated that uva damage to skin keratinocytes in vitro was similar to that for ros and that tpp protects against uva-induced cytotoxicity by inhibiting lipid peroxidation and apoptosis. |
2000-11-30 |
2023-08-12 |
rat |
| b' M MacCarrone, G Van Zadelhoff, G A Veldink, J F Vliegenthart, A Finazzi-Agr\\xc3\\xb. Early activation of lipoxygenase in lentil (Lens culinaris) root protoplasts by oxidative stress induces programmed cell death. European journal of biochemistry. vol 267. issue 16. 2000-10-18. PMID:10931190.' |
the commitment of cells to apoptosis caused by h2o2 was characterized by an early increase of lipoxygenase activity, of ultraweak luminescence and of membrane lipid peroxidation, which reached 720, 350 and 300% of controls, respectively, at 6 h after h2o2 treatment. |
2000-10-18 |
2023-08-12 |
Not clear |
| Y Soh, K S Jeong, I J Lee, M A Bae, Y C Kim, B J Son. Selective activation of the c-Jun N-terminal protein kinase pathway during 4-hydroxynonenal-induced apoptosis of PC12 cells. Molecular pharmacology. vol 58. issue 3. 2000-09-25. PMID:10953046. |
the by-product of lipid peroxidation, 4-hydroxynonenal (hne), was shown to cause apoptosis in pc12 cells. |
2000-09-25 |
2023-08-12 |
Not clear |
| S J Stohs, D Bagchi, E Hassoun, M Bagch. Oxidative mechanisms in the toxicity of chromium and cadmium ions. Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer. vol 19. issue 3. 2000-09-14. PMID:10983887. |
these reactive oxygen species result in increased lipid peroxidation, enhanced excretion of urinary lipid metabolites, modulation of intracellular oxidized states, dna damage, membrane damage, altered gene expression, and apoptosis. |
2000-09-14 |
2023-08-12 |
Not clear |
| T Böhler, J Waiser, H Hepburn, J Gaedeke, C Lehmann, P Hambach, K Budde, H H Neumaye. TNF-alpha and IL-1alpha induce apoptosis in subconfluent rat mesangial cells. Evidence for the involvement of hydrogen peroxide and lipid peroxidation as second messengers. Cytokine. vol 12. issue 7. 2000-09-08. PMID:10880243. |
coincubation with catalase inhibited tnf-alpha and il-1alpha induced apoptosis as well as lipid peroxidation. |
2000-09-08 |
2023-08-12 |
rat |
| T Böhler, J Waiser, H Hepburn, J Gaedeke, C Lehmann, P Hambach, K Budde, H H Neumaye. TNF-alpha and IL-1alpha induce apoptosis in subconfluent rat mesangial cells. Evidence for the involvement of hydrogen peroxide and lipid peroxidation as second messengers. Cytokine. vol 12. issue 7. 2000-09-08. PMID:10880243. |
these results provide evidence that tnf-alpha and il-1alpha induce apoptosis in rat mc with hydrogen peroxide and lipid peroxidation as second messengers. |
2000-09-08 |
2023-08-12 |
rat |
| Y H Lee, S Y Kim, J R Kim, K T Yoh, S H Baek, M J Kim, S H Ryu, P G Suh, J H Ki. Overexpression of phospholipase Cbeta-1 protects NIH3T3 cells from oxidative stress-induced cell death. Life sciences. vol 67. issue 7. 2000-09-07. PMID:10968412. |
oxidative stress has been implicated in a wide range of cellular damage which includes dna oxidation, membrane lipid peroxidation, and apoptosis. |
2000-09-07 |
2023-08-12 |
Not clear |
| S K Manna, A Mukhopadhyay, B B Aggarwa. Resveratrol suppresses TNF-induced activation of nuclear transcription factors NF-kappa B, activator protein-1, and apoptosis: potential role of reactive oxygen intermediates and lipid peroxidation. Journal of immunology (Baltimore, Md. : 1950). vol 164. issue 12. 2000-07-20. PMID:10843709. |
resveratrol suppresses tnf-induced activation of nuclear transcription factors nf-kappa b, activator protein-1, and apoptosis: potential role of reactive oxygen intermediates and lipid peroxidation. |
2000-07-20 |
2023-08-12 |
Not clear |
| J Li, C Y Huang, R L Zheng, K R Cui, J F L. Hydrogen peroxide induces apoptosis in human hepatoma cells and alters cell redox status. Cell biology international. vol 24. issue 1. 2000-07-10. PMID:10826769. |
the h2o2 downregulation of gsh may be more important for apoptosis than h2o2 induction of lipid peroxidation, and the h2o2 induced changes in redox status of the cell may be among the original events which lead up to other biochemical changes. |
2000-07-10 |
2023-08-12 |
human |
| G Lizard, C Miguet, G Besséde, S Monier, S Gueldry, D Neel, P Gamber. Impairment with various antioxidants of the loss of mitochondrial transmembrane potential and of the cytosolic release of cytochrome c occuring during 7-ketocholesterol-induced apoptosis. Free radical biology & medicine. vol 28. issue 5. 2000-05-25. PMID:10754270. |
previous investigations of our laboratory have shown that 7-ketocholesterol was a potent inducer of apoptosis involving a release of cytochrome c into the cytosol, and a lipid peroxidation process that could be the consequence of a production of radical oxygen species. |
2000-05-25 |
2023-08-12 |
Not clear |
| P Seth, R Kumari, S Madhavan, A K Singh, H Mani, K K Banaudha, S C Sharma, D K Kulshreshtha, R K Maheshwar. Prevention of renal ischemia-reperfusion-induced injury in rats by picroliv. Biochemical pharmacology. vol 59. issue 10. 2000-05-17. PMID:10736432. |
picroliv-pretreated rats exhibited lower lipid peroxidation, improved antioxidant status, and reduced apoptosis, indicating better viability of renal cells. |
2000-05-17 |
2023-08-12 |
rat |
| M Igarashi, T Miyazaw. Do conjugated eicosapentaenoic acid and conjugated docosahexaenoic acid induce apoptosis via lipid peroxidation in cultured human tumor cells? Biochemical and biophysical research communications. vol 270. issue 2. 2000-05-08. PMID:10753678. |
do conjugated eicosapentaenoic acid and conjugated docosahexaenoic acid induce apoptosis via lipid peroxidation in cultured human tumor cells? |
2000-05-08 |
2023-08-12 |
human |
| M Igarashi, T Miyazaw. Do conjugated eicosapentaenoic acid and conjugated docosahexaenoic acid induce apoptosis via lipid peroxidation in cultured human tumor cells? Biochemical and biophysical research communications. vol 270. issue 2. 2000-05-08. PMID:10753678. |
cepa and cdha have been demonstrated in cultured cells to cause cell death via lipid peroxidation and apoptosis in the absence of alpha-tocopherol. |
2000-05-08 |
2023-08-12 |
human |
| L J Mi, K M Mak, C S Liebe. Attenuation of alcohol-induced apoptosis of hepatocytes in rat livers by polyenylphosphatidylcholine (PPC). Alcoholism, clinical and experimental research. vol 24. issue 2. 2000-05-02. PMID:10698373. |
this effect appears to be mediated by the induction of hepatic cytochrome p-4502e1(cyp2e1) and its generation of free radicals, which results in an enhanced lipid peroxidation that initiates apoptosis. |
2000-05-02 |
2023-08-12 |
rat |
| T Huang, A G Cheng, H Stupak, W Liu, A Kim, H Staecker, P P Lefebvre, B Malgrange, R Kopke, G Moonen, T R Van De Wate. Oxidative stress-induced apoptosis of cochlear sensory cells: otoprotective strategies. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 18. issue 2-3. 2000-04-28. PMID:10715580. |
we present several approaches for the prevention of auditory sensory loss from reactive oxygen species-induced apoptosis: 1) preventing the formation of reactive oxygen species; (2) neutralizing the toxic products of membrane lipid peroxidation; and 3) blocking the damaged sensory cells' apoptotic pathway. |
2000-04-28 |
2023-08-12 |
Not clear |
| P G Fallon, E J Richardson, P Smith, D W Dunn. Elevated type 1, diminished type 2 cytokines and impaired antibody response are associated with hepatotoxicity and mortalities during Schistosoma mansoni infection of CD4-depleted mice. European journal of immunology. vol 30. issue 2. 2000-03-14. PMID:10671202. |
the livers of depleted mice had similar levels of apoptosis as control infected mice but had a marked increase in lipid peroxidation indicative of their livers being under oxidative stress. |
2000-03-14 |
2023-08-12 |
mouse |