| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jhang Ho Pak, Yefim Manevich, Han Suk Kim, Sheldon I Feinstein, Aron B Fishe. An antisense oligonucleotide to 1-cys peroxiredoxin causes lipid peroxidation and apoptosis in lung epithelial cells. The Journal of biological chemistry. vol 277. issue 51. 2003-02-12. PMID:12372839. |
an antisense oligonucleotide to 1-cys peroxiredoxin causes lipid peroxidation and apoptosis in lung epithelial cells. |
2003-02-12 |
2023-08-12 |
rat |
| Ai Chen, En-Hua Cao, Tong-Cun Zhang, Jing-Fen Qi. Arsenite-induced reactive oxygen species and the repression of alpha-tocopherol in the MGC-803 cells. European journal of pharmacology. vol 448. issue 1. 2003-02-06. PMID:12126965. |
cells exhibited obvious characteristic of apoptosis following the treatment with 1.0 microm arsenite for 24 h. during the process, low concentration of arsenite significantly increased superoxide formation and lipid peroxidation, which was dose-dependent and was related to cell apoptosis induced by arsenite. |
2003-02-06 |
2023-08-12 |
human |
| Ai Chen, En-Hua Cao, Tong-Cun Zhang, Jing-Fen Qi. Arsenite-induced reactive oxygen species and the repression of alpha-tocopherol in the MGC-803 cells. European journal of pharmacology. vol 448. issue 1. 2003-02-06. PMID:12126965. |
addition of alpha-tocopherol before arsenite treatment abolished the transient increase in superoxide formation, lipid peroxidation, intracellular [ca(2+)] levels and p53 gene expression, and furthermore could significantly inhibited the arsenite-induced apoptosis of mgc-803 cells. |
2003-02-06 |
2023-08-12 |
human |
| Aiguo Wang, Tao Xia, Peng Ran, Yun Bai, Kedi Yang, Xuemin Che. [Effects of selenium and fluoride on apoptosis and lipid peroxidation in human hepatocytes]. Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine]. vol 36. issue 4. 2003-02-05. PMID:12411202. |
[effects of selenium and fluoride on apoptosis and lipid peroxidation in human hepatocytes]. |
2003-02-05 |
2023-08-12 |
human |
| Aiguo Wang, Tao Xia, Peng Ran, Yun Bai, Kedi Yang, Xuemin Che. [Effects of selenium and fluoride on apoptosis and lipid peroxidation in human hepatocytes]. Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine]. vol 36. issue 4. 2003-02-05. PMID:12411202. |
to study the influence of selenium and fluoride on apoptosis and lipid peroxidation in human hepatocytes in vitro. |
2003-02-05 |
2023-08-12 |
human |
| Shiang-Jiuun Chen, Jia-Lin Wang, Jian-Hung Chen, Rong-Nan Huan. Possible involvement of glutathione and p53 in trichloroethylene- and perchloroethylene-induced lipid peroxidation and apoptosis in human lung cancer cells. Free radical biology & medicine. vol 33. issue 4. 2003-02-03. PMID:12160929. |
possible involvement of glutathione and p53 in trichloroethylene- and perchloroethylene-induced lipid peroxidation and apoptosis in human lung cancer cells. |
2003-02-03 |
2023-08-12 |
human |
| Shiang-Jiuun Chen, Jia-Lin Wang, Jian-Hung Chen, Rong-Nan Huan. Possible involvement of glutathione and p53 in trichloroethylene- and perchloroethylene-induced lipid peroxidation and apoptosis in human lung cancer cells. Free radical biology & medicine. vol 33. issue 4. 2003-02-03. PMID:12160929. |
the accumulation of h(2)o(2) was accompanied by severe cellular damage, as indicated by the significant increase of lipid peroxidation and apoptosis in p53-wt h460 cells, but not p53-null h1299 cells. |
2003-02-03 |
2023-08-12 |
human |
| Shane R Bruckner, Steven Estu. JNK3 contributes to c-jun induction and apoptosis in 4-hydroxynonenal-treated sympathetic neurons. Journal of neuroscience research. vol 70. issue 5. 2003-01-23. PMID:12424734. |
4-hydroxynoneal (hne), an end product of lipid peroxidation, induces apoptosis in many cell types, including neural cells. |
2003-01-23 |
2023-08-12 |
Not clear |
| C B Albano, D Muralikrishnan, M Ebad. Distribution of coenzyme Q homologues in brain. Neurochemical research. vol 27. issue 5. 2002-12-04. PMID:12064350. |
this finding is crucial in elucidating ubiquinone function in bioenergetics; in preventing free radical generation, lipid peroxidation, and apoptosis in the brain; and as a potential compound in treating various neurodegenerative disorders. |
2002-12-04 |
2023-08-12 |
mouse |
| Sukumar Chattopadhyay, Sraboni Bhaumik, Madhumita Purkayastha, Srabanti Basu, Aditi Nag Chaudhuri, Shyamal Das Gupt. Apoptosis and necrosis in developing brain cells due to arsenic toxicity and protection with antioxidants. Toxicology letters. vol 136. issue 1. 2002-12-02. PMID:12368058. |
experiments on human fetal brain explants on exposure to arsenic in culture showed disturbance in lipid peroxidation, generation of nitric oxide (no), reactive oxygen species (ros) and apoptosis. |
2002-12-02 |
2023-08-12 |
human |
| Joanne E Carter, Ai Q Truong-Tran, Dion Grosser, Lien Ho, Richard E Ruffin, Peter D Zalewsk. Involvement of redox events in caspase activation in zinc-depleted airway epithelial cells. Biochemical and biophysical research communications. vol 297. issue 4. 2002-11-27. PMID:12359264. |
depletion of intracellular zn(2+) in sheep aec, using the membrane permeant zn(2+) chelator tpen, increased lipid peroxidation in the apical cell membranes (as assessed by immunofluorescence with anti-hydroxynonenal) as well as increasing activated pro-caspase-3 and apoptosis. |
2002-11-27 |
2023-08-12 |
human |
| Dean G Tang, Eunhye La, Julie Kern, James P Kehre. Fatty acid oxidation and signaling in apoptosis. Biological chemistry. vol 383. issue 3-4. 2002-11-25. PMID:12033433. |
also, the spontaneous oxidation of polyunsaturated fatty acids yields reactive aldehydes and other products of lipid peroxidation that are potentially toxic to cells and may also signal apoptosis. |
2002-11-25 |
2023-08-12 |
Not clear |
| David Shi, Bing-Hua Jian. Antioxidant properties of apple juice and its protection against Cr(VI)-induced cellular injury. Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer. vol 21. issue 3. 2002-11-25. PMID:12435076. |
apple juice reduced cr(vi)-induced lipid peroxidation, dna damage, cell apoptosis, and nf-kappab activation in human lung epithelial a549 cells. |
2002-11-25 |
2023-08-12 |
human |
| David Shi, Bing-Hua Jian. Antioxidant properties of apple juice and its protection against Cr(VI)-induced cellular injury. Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer. vol 21. issue 3. 2002-11-25. PMID:12435076. |
the lipid peroxidation was measured by a colorimetric assay, dna damage by single cell gel electrophoresis assay, induction of cell apoptosis by flow cytometry, and activation of nf-kappab by luciferase assay. |
2002-11-25 |
2023-08-12 |
human |
| A Oliveros-Juste, V Bertol, A Oliveros-Ci. [Preventive prophylactic treatment in posttraumatic epilepsy]. Revista de neurologia. vol 34. issue 5. 2002-11-08. PMID:12040514. |
prophylactic efficacy of other drugs, like lipid peroxidation inhibitors, neuroprotectors (especially antioxidants), glutamic receptor blockers, nmda receptor blockers, and drugs that modulate apoptosis via caspasas inhibition; however, they constitute new ways of therapeutic investigation with a strong experimental basis. |
2002-11-08 |
2023-08-12 |
Not clear |
| Jeffrey J Lysiak, Quoc An T Nguyen, Terry T Turne. Peptide and nonpeptide reactive oxygen scavengers provide partial rescue of the testis after torsion. Journal of andrology. vol 23. issue 3. 2002-10-23. PMID:12002442. |
results revealed that the infusion of h2o2 increased testicular lipid peroxidation 1 hour after administration and increased germ cell apoptosis within 24 hours of administration. |
2002-10-23 |
2023-08-12 |
rat |
| BaoJun Chang, Manabu Nishikawa, Eisuke Sato, Kozo Utsumi, Masayasu Inou. L-Carnitine inhibits cisplatin-induced injury of the kidney and small intestine. Archives of biochemistry and biophysics. vol 405. issue 1. 2002-10-17. PMID:12176057. |
cisplatin-induced mitochondrial dysfunction and dna (mtdna) injury, lipid peroxidation, and apoptosis of epithelial cells in the kidney and small intestine were strongly inhibited by l-carnitine. |
2002-10-17 |
2023-08-12 |
Not clear |
| Ho-Jin Heo, Hong-Yon Cho, Bumshik Hong, Hye-Kyung Kim, Tae-Ryeon Heo, Eun-Ki Kim, Sung-Koo Kim, Chang-Ju Kim, Dong-Hoon Shi. Ursolic acid of Origanum majorana L. reduces Abeta-induced oxidative injury. Molecules and cells. vol 13. issue 1. 2002-10-10. PMID:11911474. |
amyloid beta protein (abeta) increases free radical production and lipid peroxidation in pc12 nerve cells, leading to apoptosis and cell death. |
2002-10-10 |
2023-08-12 |
Not clear |
| Irfan Rahman, Annemarie A M van Schadewijk, Ann J L Crowther, Pieter S Hiemstra, Jan Stolk, William MacNee, Willem I De Boe. 4-Hydroxy-2-nonenal, a specific lipid peroxidation product, is elevated in lungs of patients with chronic obstructive pulmonary disease. American journal of respiratory and critical care medicine. vol 166. issue 4. 2002-09-06. PMID:12186826. |
4-hydroxy-2-nonenal (4-hne), a highly reactive diffusible product of lipid peroxidation, is a key mediator of oxidant-induced cell signaling and apoptosis. |
2002-09-06 |
2023-08-12 |
human |
| Carole Miguet-Alfonsi, Céline Prunet, Serge Monier, Ginette Bessède, Stéphanie Lemaire-Ewing, Arnaud Berthier, Franck Ménétrier, Dominique Néel, Philippe Gambert, Gérard Lizar. Analysis of oxidative processes and of myelin figures formation before and after the loss of mitochondrial transmembrane potential during 7beta-hydroxycholesterol and 7-ketocholesterol-induced apoptosis: comparison with various pro-apoptotic chemicals. Biochemical pharmacology. vol 64. issue 3. 2002-09-05. PMID:12147305. |
to determine the precise relationships between cytotoxicity and oxidative stress, the ability of oxysterols oxidized at c7 to induce apoptosis, to stimulate o2*- production and to promote lipid peroxidation was compared with different pro-apoptotic chemicals: antitumoral drugs (vb, ara-c, chx, and vp-16) and sts. |
2002-09-05 |
2023-08-12 |
Not clear |