| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| G Benitez-King, I Túnez, A Bellon, G G Ortíz, F Antón-Ta. Melatonin prevents cytoskeletal alterations and oxidative stress induced by okadaic acid in N1E-115 cells. Experimental neurology. vol 182. issue 1. 2003-08-06. PMID:12821385. |
also, increased lipid peroxidation and augmented apoptosis in n1e-115 cells incubated with 50 nm oa were prevented by melatonin. |
2003-08-06 |
2023-08-12 |
Not clear |
| A V Alessenko, E I Galperin, L B Dudnik, V G Korobko, E S Mochalova, L V Platonova, L N Shingarova, N I Shono, M A Shupi. Role of tumor necrosis factor alpha and sphingomyelin cycle activation in the induction of apoptosis by ischemia/reperfusion of the liver. Biochemistry. Biokhimiia. vol 67. issue 12. 2003-08-04. PMID:12600263. |
in the present study involvement of the tnf-alpha, sphingomyelin cycle, and lipid peroxidation in the initiation of apoptosis induced in liver cells by ischemia and reperfusion was investigated. |
2003-08-04 |
2023-08-12 |
rat |
| María Teresa Ronco, Maria Luján deAlvarez, Juan Monti, María Cristina Carrillo, Gerardo Pisani, María Cristina Lugano, Cristina E Carnoval. Modulation of balance between apoptosis and proliferation by lipid peroxidation (LPO) during rat liver regeneration. Molecular medicine (Cambridge, Mass.). vol 8. issue 12. 2003-08-01. PMID:12606815. |
modulation of balance between apoptosis and proliferation by lipid peroxidation (lpo) during rat liver regeneration. |
2003-08-01 |
2023-08-12 |
rat |
| María Teresa Ronco, Maria Luján deAlvarez, Juan Monti, María Cristina Carrillo, Gerardo Pisani, María Cristina Lugano, Cristina E Carnoval. Modulation of balance between apoptosis and proliferation by lipid peroxidation (LPO) during rat liver regeneration. Molecular medicine (Cambridge, Mass.). vol 8. issue 12. 2003-08-01. PMID:12606815. |
this work aims to investigate the role of lipid peroxidation (lpo) at early stages of liver regeneration and to evaluate the balance between apoptosis and cell proliferation during this process. |
2003-08-01 |
2023-08-12 |
rat |
| Yashin Sreenivasan, Abira Sarkar, Sunil K Mann. Mechanism of cytosine arabinoside-mediated apoptosis: role of Rel A (p65) dephosphorylation. Oncogene. vol 22. issue 28. 2003-08-01. PMID:12853972. |
arac, but not tnf or ceramide was able to induce apoptosis in these cells as detected by assays for lipid peroxidation, reactive oxygen intermediates generation, caspase activation, cytotoxicity, bcl-2 degradation, and dna fragmentation. |
2003-08-01 |
2023-08-12 |
Not clear |
| Ali Ozdulger, Ismail Cinel, Oguz Koksel, Leyla Cinel, Dincer Avlan, Ali Unlu, Hulya Okcu, Murat Dikmengil, Ugur Ora. The protective effect of N-acetylcysteine on apoptotic lung injury in cecal ligation and puncture-induced sepsis model. Shock (Augusta, Ga.). vol 19. issue 4. 2003-07-14. PMID:12688549. |
in conclusion, the chronic use of nac inhibited mpo activity and lipid peroxidation, which resulted in reduction of apoptosis in lung in this clp model. |
2003-07-14 |
2023-08-12 |
rat |
| C Matthew Peterson, Jane-Guo Shiah, Yongen Sun, Pavla Kopecková, Tamara Minko, Richard C Straight, Jindrich Kopece. HPMA copolymer delivery of chemotherapy and photodynamic therapy in ovarian cancer. Advances in experimental medicine and biology. vol 519. 2003-06-19. PMID:12675211. |
it demonstrates marked advantages over free doxorubicin: control of biodistribution and accumulation via molecular weight restrictions, biodegradability, minimal immunogenicity, subcellular localization, anticancer activity, enhanced permeability and retention, increased apoptosis, lipid peroxidation, dna damage, and reduced nonspecific toxicity. |
2003-06-19 |
2023-08-12 |
Not clear |
| G G Ziangirova, O V Antonov. [Local senile ocular amyloidosis in the pathogenesis of open-angle glaucoma and pseudo-exfoliative syndrome]. Vestnik Rossiiskoi akademii meditsinskikh nauk. issue 2. 2003-06-17. PMID:12698889. |
amyloid angiopathy of the iris is a key element of ischemia, which triggers the mechanisms of apoptosis and lipid peroxidation in the pigment epithelium membranes; this process is accompanied by an intensified synthesis and conformation of fibrous structures of tauprotein and beta-amyloid. |
2003-06-17 |
2023-08-12 |
Not clear |
| Oxana R Kunduzova, Ghislaine Escourrou, Marie-Helene Seguelas, Philippe Delagrange, France De La Farge, Claudie Cambon, Angelo Parin. Prevention of apoptotic and necrotic cell death, caspase-3 activation, and renal dysfunction by melatonin after ischemia/reperfusion. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 17. issue 8. 2003-06-02. PMID:12670883. |
using an in vivo rat model of i/r, we show a significant increase in kidney malondialdehyde concentrations, reflecting lipid peroxidation, and cell apoptosis measured by tunel staining. |
2003-06-02 |
2023-08-12 |
rat |
| Oxana R Kunduzova, Ghislaine Escourrou, Marie-Helene Seguelas, Philippe Delagrange, France De La Farge, Claudie Cambon, Angelo Parin. Prevention of apoptotic and necrotic cell death, caspase-3 activation, and renal dysfunction by melatonin after ischemia/reperfusion. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 17. issue 8. 2003-06-02. PMID:12670883. |
rat pretreatment with melatonin prevented lipid peroxidation, cell apoptosis, and necrosis and blocked caspase-3 activity. |
2003-06-02 |
2023-08-12 |
rat |
| T Xiao, S Choudhary, W Zhang, N H Ansari, A Salahudee. Possible involvement of oxidative stress in cisplatin-induced apoptosis in LLC-PK1 cells. Journal of toxicology and environmental health. Part A. vol 66. issue 5. 2003-05-07. PMID:12712633. |
it has been suggested that free radical-catalyzed lipid peroxidation can induce apoptosis or necrosis leading to renal injury. |
2003-05-07 |
2023-08-12 |
Not clear |
| C Lambert, O Thews, H K Biesalski, P Vaupel, D K Kelleher, Juergen Fran. 2-Methoxyestradiol enhances reactive oxygen species formation and increases the efficacy of oxygen radical generating tumor treatment. European journal of medical research. vol 7. issue 9. 2003-04-14. PMID:12435619. |
concentration-dependent increases in ros-formation, lipid peroxidation and mitochondrial changes were also observed, and an elevation in caspase-3 activity resulted in dna fragmentation and apoptosis. |
2003-04-14 |
2023-08-12 |
rat |
| Declan A Healy, R William G Watson, Philip Newsholm. Polyunsaturated and monounsaturated fatty acids increase neutral lipid accumulation, caspase activation and apoptosis in a neutrophil-like, differentiated HL-60 cell line. Clinical science (London, England : 1979). vol 104. issue 2. 2003-03-31. PMID:12546639. |
lipid peroxidation was also increased in the presence of pufas, but was not responsible for activating cell apoptosis. |
2003-03-31 |
2023-08-12 |
Not clear |
| Masaharu Hayashi, Nobutaka Arai, Junichi Satoh, Hisaharu Suzuki, Kazunobu Katayama, Kimiko Tamagawa, Yoshio Morimats. Neurodegenerative mechanisms in subacute sclerosing panencephalitis. Journal of child neurology. vol 17. issue 10. 2003-03-14. PMID:12546425. |
it is speculated in subacute sclerosing panencephalitis that apoptosis and oxidative stress to dna can contribute to the early neuronal damage, whereas lipid peroxidation and disturbed glutamate transport may be related to the subsequent neurodegeneration. |
2003-03-14 |
2023-08-12 |
Not clear |
| Tsugunobu Andoh, Chuang Chin Chiueh, P Boon Choc. Cyclic GMP-dependent protein kinase regulates the expression of thioredoxin and thioredoxin peroxidase-1 during hormesis in response to oxidative stress-induced apoptosis. The Journal of biological chemistry. vol 278. issue 2. 2003-03-07. PMID:12414792. |
the activated pkg is required to protect cells from lipid peroxidation and apoptosis, to inhibit caspase-9 and caspase-3 activation, and to elevate the levels of trx peroxidase-1 and trx, which subsequently induces the expression of bcl-2. |
2003-03-07 |
2023-08-12 |
human |
| F M Boffi, J Cittar, G Balskus, M Muriel, E Desmara. Training-induced apoptosis in skeletal muscle. Equine veterinary journal. Supplement. issue 34. 2003-02-26. PMID:12405700. |
in addition, muscle biopsy samples were obtained for a membrane lipid peroxidation measurement by malondialdehyde (mda) assay and for apoptosis detection. |
2003-02-26 |
2023-08-12 |
Not clear |
| S Choudhary, W Zhang, F Zhou, G A Campbell, L L Chan, E B Thompson, N H Ansar. Cellular lipid peroxidation end-products induce apoptosis in human lens epithelial cells. Free radical biology & medicine. vol 32. issue 4. 2003-02-24. PMID:11841926. |
cellular lipid peroxidation end-products induce apoptosis in human lens epithelial cells. |
2003-02-24 |
2023-08-12 |
human |
| S Choudhary, W Zhang, F Zhou, G A Campbell, L L Chan, E B Thompson, N H Ansar. Cellular lipid peroxidation end-products induce apoptosis in human lens epithelial cells. Free radical biology & medicine. vol 32. issue 4. 2003-02-24. PMID:11841926. |
since h(2)o(2) causes lipid peroxidation leading to the formation of reactive end-products, it is important to investigate whether the end-products of lipid peroxidation are involved in the oxidation-induced apoptosis in the lens. |
2003-02-24 |
2023-08-12 |
human |
| S Choudhary, W Zhang, F Zhou, G A Campbell, L L Chan, E B Thompson, N H Ansar. Cellular lipid peroxidation end-products induce apoptosis in human lens epithelial cells. Free radical biology & medicine. vol 32. issue 4. 2003-02-24. PMID:11841926. |
taken together, the results demonstrate the apoptotic potential of the lipid peroxidation end-products and suggest that h(2)o(2)-induced apoptosis may be mediated by these end-products in the lens epithelium. |
2003-02-24 |
2023-08-12 |
human |
| I Ahmed, A John, C Vijayasarathy, M A Robin, H Raz. Differential modulation of growth and glutathione metabolism in cultured rat astrocytes by 4-hydroxynonenal and green tea polyphenol, epigallocatechin-3-gallate. Neurotoxicology. vol 23. issue 3. 2003-02-21. PMID:12387357. |
4-hydroxynonenal (hne), a by-product of lipid peroxidation (lpo), has been reported to induce apoptosis and inhibit growth in many cell systems including neuroglial cultures. |
2003-02-21 |
2023-08-12 |
rat |