| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| James D West, Chuan Ji, Lawrence J Marnet. Modulation of DNA fragmentation factor 40 nuclease activity by poly(ADP-ribose) polymerase-1. The Journal of biological chemistry. vol 280. issue 15. 2005-06-07. PMID:15703174. |
parp-1 poly(adp-ribosyl)ation correlated directly with induction of apoptosis by the lipid peroxidation product, 4-hydroxy-2-nonenal. |
2005-06-07 |
2023-08-12 |
Not clear |
| M Volkan Aydin, Hakan Caner, Orhan Sen, Ozlem Ozen, Basar Atalay, Melih Cekinmez, Nur Altinor. Effect of melatonin on cerebral vasospasm following experimental subarachnoid hemorrhage. Neurological research. vol 27. issue 1. 2005-05-27. PMID:15829164. |
the current study was undertaken to determine whether melatonin therapy reverses vasospasm and prevents apoptosis by inhibiting lipid peroxidation in an experimental subarachnoid hemorrhage (sah) model. |
2005-05-27 |
2023-08-12 |
Not clear |
| Elzbieta Bonda, Tadeusz Włostowski, Alicja Krasowsk. Testicular toxicity induced by dietary cadmium is associated with decreased testicular zinc and increased hepatic and renal metallothionein and zinc in the bank vole (Clethrionomys glareolus). Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine. vol 17. issue 6. 2005-05-19. PMID:15689104. |
the cd-induced histopathological changes and apoptosis were accompanied by increased testicular lipid peroxidation, decreased testicular zn concentration and elevated levels of hepatic and renal mt and zn. |
2005-05-19 |
2023-08-12 |
Not clear |
| Aysun Ozkan, Kayahan Fişki. Epirubicin HCl toxicity in human-liver derived hepatoma G2 cells. Polish journal of pharmacology. vol 56. issue 4. 2005-05-13. PMID:15520498. |
it is proposed that production of reactive oxygen species increased by the treatment with epirubicin hcl can cause lipid peroxidation, which subsequently promotes apoptosis and reduces cell viability. |
2005-05-13 |
2023-08-12 |
Not clear |
| Kodipura Doreswamy, Balakrishna Shrilatha, Thimappa Rajeshkumar, Muralidhar. Nickel-induced oxidative stress in testis of mice: evidence of DNA damage and genotoxic effects. Journal of andrology. vol 25. issue 6. 2005-05-02. PMID:15477375. |
subsequently, multiple sublethal doses (1.25, 2.5, and 5.0 micromol/100 g of body weight per day for 3 days) were used to characterize effects on testicular histoarchitecture, lipid peroxidation (lpo) in testis (homogenates, microsomal or mitochondrial fractions) and epididymal sperm, dna damage, induction of apoptosis in testis, and incidence of sperm head abnormalities. |
2005-05-02 |
2023-08-12 |
mouse |
| Ji-Seon Lee, Jong-Sun Chang, Ji Youl Lee, Jung-Ae Ki. Capsaicin-induced apoptosis and reduced release of reactive oxygen species in MBT-2 murine bladder tumor cells. Archives of pharmacal research. vol 27. issue 11. 2005-03-30. PMID:15595419. |
furthermore, capsaicin at the concentration of inducing apoptosis also markedly reduced the level of reactive oxygen species and lipid peroxidation, implying that capsaicin may enhance the antitumor effect of bcg in bladder cancer treatment. |
2005-03-30 |
2023-08-12 |
Not clear |
| Saul R Powell, Lin L Mantell, Valerie Garramone, Steven Drexler, Saul Teichber. Acute effects of nonlethal in utero hypoxia on fetal guinea pig heart and lack of persistent cardiac or cerebral effects in the neonate. Biology of the neonate. vol 86. issue 4. 2005-03-17. PMID:15273443. |
guinea pigs (50-55 days gestation) were exposed to 7% o2 for 2 h and room air for 4 h. fetal hearts were harvested before hypoxia, at the end of hypoxia, and 4 h after hypoxia, and analyzed for: apoptosis (tunel), histology, lipid peroxidation and atp. |
2005-03-17 |
2023-08-12 |
Not clear |
| James P Fabisiak, Grigory G Borisenko, Valerian E Kaga. Quantitative method of measuring phosphatidylserine externalization during apoptosis using electron paramagnetic resonance spectroscopy and annexin-conjugated iron. Methods in molecular biology (Clifton, N.J.). vol 291. 2005-02-22. PMID:15502242. |
the application of this technique, alone and in concert with the ps oxidation method presented in the previous chapter, will greatly aid in studying the mechanistic connection between lipid peroxidation and translocation events during apoptosis. |
2005-02-22 |
2023-08-12 |
Not clear |
| Behzat Cimen, Nurten Türközkan, Ilgim Seven, Ali Unlü, Cimen Karas. Impaired Na+,K+-ATPase activity as a mechanism of reactive nitrogen species-induced cytotoxicity in guinea pig liver exposed to lipopolysaccharides. Molecular and cellular biochemistry. vol 259. issue 1-2. 2005-01-25. PMID:15124907. |
in animal models of endotoxin, the excess production of no and the reactive nitrogen species (rns), are potent oxidant and nitrating agents, lead to lipid peroxidation, apoptosis, tissue dysfunction and injury and inactivate enzymes in many cell types. |
2005-01-25 |
2023-08-12 |
Not clear |
| Paresh Manna, Krishnan K Narang, Sunil K Mann. 1,2,4-Thiadiazolidine derivative inhibits nuclear transcription factor-kappaB and its dependent genes activation but induces apoptosis. International journal of cancer. vol 113. issue 4. 2005-01-19. PMID:15389516. |
unlike other substitutary derivatives, p(3)-25 was a potent inducer of apoptosis as it induced cell death, caspase-dependent parp cleavage, roi generation and lipid peroxidation. |
2005-01-19 |
2023-08-12 |
human |
| Futoshi Hirai, Shigeatsu Motoori, Shizuko Kakinuma, Kazuo Tomita, Hiroko P Indo, Hirotoshi Kato, Taketo Yamaguchi, Hsiu-Chuan Yen, Daret K St Clair, Tetsuo Nagano, Toshihiko Ozawa, Hiromitsu Saisho, Hideyuki J Majim. Mitochondrial signal lacking manganese superoxide dismutase failed to prevent cell death by reoxygenation following hypoxia in a human pancreatic cancer cell line, KP4. Antioxidants & redox signaling. vol 6. issue 3. 2004-12-10. PMID:15130279. |
normal human mnsod and mnsod without a mitochondrial targeting signal were transfected to kp4 cells, and reactive oxygen species, nitric oxide, lipid peroxidation, and apoptosis were examined as a function of time in air following 1 day of hypoxia as a h/r model. |
2004-12-10 |
2023-08-12 |
human |
| Ai-Guo Wang, Tao Xia, Qi-Long Chu, Ming Zhang, Fang Liu, Xue-Min Chen, Ke-Di Yan. Effects of fluoride on lipid peroxidation, DNA damage and apoptosis in human embryo hepatocytes. Biomedical and environmental sciences : BES. vol 17. issue 2. 2004-12-10. PMID:15386948. |
effects of fluoride on lipid peroxidation, dna damage and apoptosis in human embryo hepatocytes. |
2004-12-10 |
2023-08-12 |
human |
| Ai-Guo Wang, Tao Xia, Qi-Long Chu, Ming Zhang, Fang Liu, Xue-Min Chen, Ke-Di Yan. Effects of fluoride on lipid peroxidation, DNA damage and apoptosis in human embryo hepatocytes. Biomedical and environmental sciences : BES. vol 17. issue 2. 2004-12-10. PMID:15386948. |
to investigate the effects of fluoride on lipid peroxidation, dna damage and apoptosis in human embryo hepatocyte l-02 cells. |
2004-12-10 |
2023-08-12 |
human |
| H A Leaver, J R Williams, C Smith, I R Whittl. Intracellular oxidation by human glioma cell populations: effect of arachidonic acid. Prostaglandins, leukotrienes, and essential fatty acids. vol 70. issue 5. 2004-11-30. PMID:15062847. |
arachidonic acid (aa) and gamma linolenic acid have been shown to limit glioma cell growth, stimulate apoptosis and lipid peroxidation. |
2004-11-30 |
2023-08-12 |
human |
| Rukhsana Sultana, Shelley Newman, Hafiz Mohmmad-Abdul, Jeffery N Keller, D Allan Butterfiel. Protective effect of the xanthate, D609, on Alzheimer's amyloid beta-peptide (1-42)-induced oxidative stress in primary neuronal cells. Free radical research. vol 38. issue 5. 2004-11-23. PMID:15293552. |
pretreatment of primary hippocampal cultures with d609 significantly attenuated abeta(1-42)-induced cytotoxicity, intracellular ros accumulation, protein oxidation, lipid peroxidation and apoptosis. |
2004-11-23 |
2023-08-12 |
Not clear |
| Maristella C Anazetti, Patricia S Melo, Nelson Durán, Marcela Hau. Dehydrocrotonin and its derivative, dimethylamide-crotonin induce apoptosis with lipid peroxidation and activation of caspases-2, -6 and -9 in human leukemic cells HL60. Toxicology. vol 203. issue 1-3. 2004-11-19. PMID:15363588. |
dehydrocrotonin and its derivative, dimethylamide-crotonin induce apoptosis with lipid peroxidation and activation of caspases-2, -6 and -9 in human leukemic cells hl60. |
2004-11-19 |
2023-08-12 |
human |
| Maristella C Anazetti, Patricia S Melo, Nelson Durán, Marcela Hau. Dehydrocrotonin and its derivative, dimethylamide-crotonin induce apoptosis with lipid peroxidation and activation of caspases-2, -6 and -9 in human leukemic cells HL60. Toxicology. vol 203. issue 1-3. 2004-11-19. PMID:15363588. |
these results indicate that dcr and dhc produced apoptosis partly by oxidative stress-induced lipid peroxidation, which triggered the caspase cascade, that lead to apoptotic cell death in hl60 cells. |
2004-11-19 |
2023-08-12 |
human |
| Tatiana Armeni, Elisabetta Damiani, Maurizio Battino, Lucedio Greci, Giovanni Principat. Lack of in vitro protection by a common sunscreen ingredient on UVA-induced cytotoxicity in keratinocytes. Toxicology. vol 203. issue 1-3. 2004-11-19. PMID:15363592. |
the results obtained show that uva exposure induces significant cell mortality, decrease in protein concentration, release of ldh, increase in apoptosis, oxidative stress and lipid peroxidation with a concomitant reduction in the response of the antioxidant cellular defense system. |
2004-11-19 |
2023-08-12 |
human |
| Melanie Baumgartner, Sanda Sturlan, Erich Roth, Barbara Wessner, Thomas Bachleitner-Hofman. Enhancement of arsenic trioxide-mediated apoptosis using docosahexaenoic acid in arsenic trioxide-resistant solid tumor cells. International journal of cancer. vol 112. issue 4. 2004-11-16. PMID:15382055. |
the cytotoxic effect of as2o3 and dha was associated with the induction of apoptosis and a concomitant increase of intracellular lipid peroxidation products. |
2004-11-16 |
2023-08-12 |
human |
| Jordi Roca, Maria A Gil, Marta Hernandez, Inma Parrilla, Juan M Vazquez, Emilio A Martine. Survival and fertility of boar spermatozoa after freeze-thawing in extender supplemented with butylated hydroxytoluene. Journal of andrology. vol 25. issue 3. 2004-11-09. PMID:15064318. |
in experiment 2, sperm survivability was evaluated when bht was added to a postthaw freezing extender by measuring the degree of sperm lipid peroxidation (using mda production) and by measuring parameter such as motility, plasma membrane and acrosome integrity, and cell apoptosis. |
2004-11-09 |
2023-08-12 |
Not clear |