| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Engin Yenilmez, Sermet Yildirmis, Esin Yulug, Sevim Aydin, Yavuz Tekelioglu, Erkan Erdem, Murat Topbas, Haluk Arva. Ham's F-10 medium and Ham's F-10 medium plus vitamin E have protective effect against oxidative stress in human semen. Urology. vol 67. issue 2. 2006-03-31. PMID:16461090. |
to investigate possible protective effects of vitamin e and ham's f-10 medium (hf-10) on lipid peroxidation, apoptosis, motility, and vitality of spermatozoa. |
2006-03-31 |
2023-08-12 |
human |
| b' Mar\\xc3\\xada Francisca Molina-Jim\\xc3\\xa9nez, Mar\\xc3\\xada Isabel S\\xc3\\xa1nchez-Reus, Mar\\xc3\\xada Cascales, David Andr\\xc3\\xa9s, Juana Bened\\xc3\\xa. Effect of fraxetin on antioxidant defense and stress proteins in human neuroblastoma cell model of rotenone neurotoxicity. Comparative study with myricetin and N-acetylcysteine. Toxicology and applied pharmacology. vol 209. issue 3. 2006-03-17. PMID:15904944.' |
recently, it has been shown that fraxetin (coumarin) and myricetin (flavonoid) have significant neuroprotective effects against apoptosis induced by rotenone, increase the total glutathione levels in vitro, and inhibit lipid peroxidation. |
2006-03-17 |
2023-08-12 |
human |
| Jian Zhuge, Arthur I Cederbau. Serum deprivation-induced HepG2 cell death is potentiated by CYP2E1. Free radical biology & medicine. vol 40. issue 1. 2006-03-16. PMID:16337880. |
we propose that the mechanism of this serum withdrawal plus cyp2e1 toxicity involves increased production of intracellular ros, lipid peroxidation, and decline of gsh levels, which results in mitochondrial membrane damage and loss of membrane potential, followed by apoptosis. |
2006-03-16 |
2023-08-12 |
human |
| Catherine Plin, Jean-Paul Tillement, Alain Berdeaux, Didier Mori. Resveratrol protects against cold ischemia-warm reoxygenation-induced damages to mitochondria and cells in rat liver. European journal of pharmacology. vol 528. issue 1-3. 2006-03-09. PMID:16325807. |
cpwr induced liver mitochondrial and cellular damages as attested by the increase in lipid peroxidation of liver membranes, the alteration of oxidative phosphorylation parameters, mitochondrial swelling and the activation of the cellular markers of necrosis and apoptosis, i.e., lactate dehydrogenase (ldh) leakage, mitochondrial cytochrome c release and caspase activation. |
2006-03-09 |
2023-08-12 |
rat |
| Wenying Jian, Jasbir S Arora, Tomoyuki Oe, Vladimir V Shuvaev, Ian A Blai. Induction of endothelial cell apoptosis by lipid hydroperoxide-derived bifunctional electrophiles. Free radical biology & medicine. vol 39. issue 9. 2006-02-23. PMID:16214032. |
lipid peroxidation, which occurs during oxidative stress, results in the formation of lipid hydroperoxide-derived bifunctional electrophiles such as 4-hydroxy-2(e)-nonenal that induce apoptosis. |
2006-02-23 |
2023-08-12 |
Not clear |
| Koyeli Bose Girigoswami, Rita Ghos. Response to gamma-irradiation in V79 cells conditioned by repeated treatment with low doses of hydrogen peroxide. Radiation and environmental biophysics. vol 44. issue 2. 2006-02-22. PMID:16136317. |
when exposed to gamma-rays, they suffered from lipid peroxidation to a lesser extent, were more resistant to cell killing, exhibited higher mutation frequency at the hgprt locus, and showed lower frequency of apoptosis. |
2006-02-22 |
2023-08-12 |
Not clear |
| Kerim Cagli, Cahit Bagci, Mukaddes Gulec, Beyhan Cengiz, Omer Akyol, Ibrahim Sari, Sevgi Cavdar, Sadrettin Pence, Hakan Dincka. In vivo effects of caffeic acid phenethyl ester on myocardial ischemia-reperfusion injury and apoptotic changes in rats. Annals of clinical and laboratory science. vol 35. issue 4. 2006-02-14. PMID:16254262. |
i/r resulted in myocardial apoptosis, alterations of antioxidant status, elevation of serum creatine kinase (ck) and aspartate aminotransferase (ast) activities, evidence of lipid peroxidation, and elevated nitric oxide levels, compared to the sham-operation group. |
2006-02-14 |
2023-08-12 |
rat |
| Grant A Ramm, Richard G Ruddel. Hepatotoxicity of iron overload: mechanisms of iron-induced hepatic fibrogenesis. Seminars in liver disease. vol 25. issue 4. 2006-02-14. PMID:16315137. |
in the liver, lipid peroxidation results in damage to hepatocellular organelles, such as mitochondria and lysosomes, which is thought to contribute to hepatocyte necrosis and apoptosis, and ultimately lead to the development of hepatic fibrogenesis. |
2006-02-14 |
2023-08-12 |
Not clear |
| I B Afanas'e. Superoxide and nitric oxide in pathological conditions associated with iron overload: the effects of antioxidants and chelators. Current medicinal chemistry. vol 12. issue 23. 2006-02-08. PMID:16305468. |
furthermore free radical reactions leading to lipid peroxidation, ldl oxidation, the stimulation of apoptosis and other damaging processes are discussed. |
2006-02-08 |
2023-08-12 |
Not clear |
| Qun Wang, Albert Y Sun, Agnes Simonyi, Michael D Jensen, Phullara B Shelat, George E Rottinghaus, Ruth S MacDonald, Dennis K Miller, Dennis E Lubahn, Gary A Weisman, Grace Y Su. Neuroprotective mechanisms of curcumin against cerebral ischemia-induced neuronal apoptosis and behavioral deficits. Journal of neuroscience research. vol 82. issue 1. 2006-02-07. PMID:16075466. |
these ischemic changes were preceded by a rapid increase in lipid peroxidation and followed by decrease in mitochondrial membrane potential, increased cytochrome c release, and subsequently caspase-3 activation and apoptosis. |
2006-02-07 |
2023-08-12 |
Not clear |
| Jörn M Schattenberg, Rajat Singh, Yongjun Wang, Jay H Lefkowitch, Raina M Rigoli, Philipp E Scherer, Mark J Czaj. JNK1 but not JNK2 promotes the development of steatohepatitis in mice. Hepatology (Baltimore, Md.). vol 43. issue 1. 2006-01-24. PMID:16374858. |
jnk promoted the development of steatohepatitis as mcd diet-fed jnk1 null mice had significantly reduced levels of hepatic triglyceride accumulation, inflammation, lipid peroxidation, liver injury, and apoptosis compared with wild-type and jnk2 -/- mice. |
2006-01-24 |
2023-08-12 |
mouse |
| Sirikarnt Dhitavat, Daniela Ortiz, Eugene Rogers, Ezequiel Rivera, Thomas B She. Folate, vitamin E, and acetyl-L-carnitine provide synergistic protection against oxidative stress resulting from exposure of human neuroblastoma cells to amyloid-beta. Brain research. vol 1061. issue 2. 2006-01-17. PMID:16256963. |
the neurotoxic peptide amyloid-beta (abeta) contributes to oxidative damage in ad by inducing lipid peroxidation, which in turn generates additional downstream cytosolic free radicals and reactive oxygen species (ros), leading to mitochondrial and cytoskeletal compromise, depletion of atp, and ultimate apoptosis. |
2006-01-17 |
2023-08-12 |
human |
| Nicolo Merendino, Barbara Loppi, Massimo D'Aquino, Romina Molinari, Gloria Pessina, Chiara Romano, Francesca Velott. Docosahexaenoic acid induces apoptosis in the human PaCa-44 pancreatic cancer cell line by active reduced glutathione extrusion and lipid peroxidation. Nutrition and cancer. vol 52. issue 2. 2006-01-12. PMID:16201853. |
docosahexaenoic acid induces apoptosis in the human paca-44 pancreatic cancer cell line by active reduced glutathione extrusion and lipid peroxidation. |
2006-01-12 |
2023-08-12 |
human |
| Nicolo Merendino, Barbara Loppi, Massimo D'Aquino, Romina Molinari, Gloria Pessina, Chiara Romano, Francesca Velott. Docosahexaenoic acid induces apoptosis in the human PaCa-44 pancreatic cancer cell line by active reduced glutathione extrusion and lipid peroxidation. Nutrition and cancer. vol 52. issue 2. 2006-01-12. PMID:16201853. |
an oxidative process was implicated in apoptosis induced by dha because butylated hydroxytoluene and vitamin e prevented lipid peroxidation and reversed apoptosis. |
2006-01-12 |
2023-08-12 |
human |
| Nicolo Merendino, Barbara Loppi, Massimo D'Aquino, Romina Molinari, Gloria Pessina, Chiara Romano, Francesca Velott. Docosahexaenoic acid induces apoptosis in the human PaCa-44 pancreatic cancer cell line by active reduced glutathione extrusion and lipid peroxidation. Nutrition and cancer. vol 52. issue 2. 2006-01-12. PMID:16201853. |
inhibition of active gsh extrusion from the cell by cystathionine or methionine completely reversed lipid peroxidation and apoptosis. |
2006-01-12 |
2023-08-12 |
human |
| Mauro Maccarrone, Monica Bari, Valeria Gasperi, Barbara Demmig-Adam. The photoreceptor protector zeaxanthin induces cell death in neuroblastoma cells. Anticancer research. vol 25. issue 6B. 2006-01-05. PMID:16309173. |
this study examined the effect of zeaxanthin on neuroblastoma cells in which apoptosis can be induced with lipid peroxidation products. |
2006-01-05 |
2023-08-12 |
Not clear |
| Mauro Maccarrone, Monica Bari, Valeria Gasperi, Barbara Demmig-Adam. The photoreceptor protector zeaxanthin induces cell death in neuroblastoma cells. Anticancer research. vol 25. issue 6B. 2006-01-05. PMID:16309173. |
since zeaxanthin can inhibit lipid peroxidation and beta-carotene inhibits lipoxygenase (lox) activity, it was of concern that zeaxanthin might inhibit apoptosis in these cancer cells. |
2006-01-05 |
2023-08-12 |
Not clear |
| Kesheng Zhao, Guoxiong Luo, Serena Giannelli, Hazel H Szet. Mitochondria-targeted peptide prevents mitochondrial depolarization and apoptosis induced by tert-butyl hydroperoxide in neuronal cell lines. Biochemical pharmacology. vol 70. issue 12. 2005-12-30. PMID:16216225. |
treatment with tert-butyl hydroperoxide (tbhp) for 24 h resulted in lipid peroxidation and significant cell death via apoptosis in both n2a and sh-sy5y cells, with phosphatidylserine translocation, nuclear condensation and increased caspase activity. |
2005-12-30 |
2023-08-12 |
Not clear |
| Yumiko Nagano, Hirofumi Matsui, Mutsumi Muramatsu, Osamu Shimokawa, Takeshi Shibahara, Akinori Yanaka, Akira Nakahara, Yasushi Matsuzaki, Naomi Tanaka, Yukio Nakamur. Rebamipide significantly inhibits indomethacin-induced mitochondrial damage, lipid peroxidation, and apoptosis in gastric epithelial RGM-1 cells. Digestive diseases and sciences. vol 50 Suppl 1. 2005-11-14. PMID:16184425. |
rebamipide significantly inhibits indomethacin-induced mitochondrial damage, lipid peroxidation, and apoptosis in gastric epithelial rgm-1 cells. |
2005-11-14 |
2023-08-12 |
Not clear |
| Yumiko Nagano, Hirofumi Matsui, Mutsumi Muramatsu, Osamu Shimokawa, Takeshi Shibahara, Akinori Yanaka, Akira Nakahara, Yasushi Matsuzaki, Naomi Tanaka, Yukio Nakamur. Rebamipide significantly inhibits indomethacin-induced mitochondrial damage, lipid peroxidation, and apoptosis in gastric epithelial RGM-1 cells. Digestive diseases and sciences. vol 50 Suppl 1. 2005-11-14. PMID:16184425. |
nsaids were recently reported to cause mitochondrial injury: to dissipate the mitochondrial transmembrane potential (mtp), and to induce mitochondrial permeability transition pore (ptp), which liberates cytochrome c. this enzyme generates reactive oxygen species (ros) thereby triggers caspase cascade and cellular lipid peroxidation, resulting in cellular apoptosis. |
2005-11-14 |
2023-08-12 |
Not clear |