| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Marzena Podhorska-Okolow, Piotr Dziegiel, Eugenia Murawska-Cialowicz, Jolanta Saczko, Julita Kulbacka, Agnieszka Gomulkiewicz, Katia Rossini, Zbigniew Jethon, Ugo Carraro, Maciej Zabe. Effects of adaptive exercise on apoptosis in cells of rat renal tubuli. European journal of applied physiology. vol 99. issue 3. 2007-04-20. PMID:17102979. |
we measured apoptosis, expression of at1 and at2 receptors, level of lipid peroxidation (tbars) and activities of antioxidant enzymes, sod, gpx and cat in kidneys of sedentary rats that were exposed to acute exercise and rats that were trained for 8 weeks. |
2007-04-20 |
2023-08-12 |
rat |
| Mehmet Guney, Baha Oral, Gulnur Take, Seren Gulsen Giray, Tamer Munga. Effect of fluoride intoxication on endometrial apoptosis and lipid peroxidation in rats: role of vitamins E and C. Toxicology. vol 231. issue 2-3. 2007-04-17. PMID:17227693. |
effect of fluoride intoxication on endometrial apoptosis and lipid peroxidation in rats: role of vitamins e and c. fluoride is a strong, hard anion and cumulative toxic agent. |
2007-04-17 |
2023-08-12 |
rat |
| Mehmet Guney, Baha Oral, Gulnur Take, Seren Gulsen Giray, Tamer Munga. Effect of fluoride intoxication on endometrial apoptosis and lipid peroxidation in rats: role of vitamins E and C. Toxicology. vol 231. issue 2-3. 2007-04-17. PMID:17227693. |
from these results, it can be concluded that subchronic fluoride administration causes endometrial apoptosis, and lipid peroxidation may be a molecular mechanism involved in fluoride-induced toxicity. |
2007-04-17 |
2023-08-12 |
rat |
| L B Dudnik, A N Tsiupko, M A Shupik, G G Akhaladze, E I Gal'perin, L V Platonova, E A Pantaz, V V Iasnetsov, L D Smirnov, A V Alesenk. [Relationship of tumor necrosis factor alpha expression with activation of sphingomyelinase and lipid peroxidation after removal of cholestatic factor]. Izvestiia Akademii nauk. Seriia biologicheskaia. issue 1. 2007-04-12. PMID:17352195. |
the obtained data indicate that hepatocyte apoptosis after bile outflow restoration in late cholestasis can be due to the activation of the sphingomyelin cycle, lpo, and tnfalpha expression. |
2007-04-12 |
2023-08-12 |
Not clear |
| L B Dudnik, A N Tsiupko, M A Shupik, G G Akhaladze, E I Gal'perin, L V Platonova, E A Pantaz, V V Iasnetsov, L D Smirnov, A V Alesenk. [Relationship of tumor necrosis factor alpha expression with activation of sphingomyelinase and lipid peroxidation after removal of cholestatic factor]. Izvestiia Akademii nauk. Seriia biologicheskaia. issue 1. 2007-04-12. PMID:17352195. |
the synergistic interaction can sharply increase the proapoptotic capacity of each of these factors since tnfalpha activates smase and lpo, smase activity depends on the lpo rate, while ceramide, an smase-produced secondary messenger of apoptosis, can induce oxidative stress. |
2007-04-12 |
2023-08-12 |
Not clear |
| Mehboob Ali, Shakilur Rahman, Hasibur Rehman, Kanchan Bhatia, Rizwan A Ansari, Sheikh Raisuddi. Pro-apoptotic effect of fly ash leachates in hepatocytes of freshwater fish (Channa punctata Bloch). Toxicology in vitro : an international journal published in association with BIBRA. vol 21. issue 1. 2007-04-09. PMID:17052884. |
lactate dehydrogenase, lpo and apoptosis as biomarkers of cytotoxicity have recently been used for assessment of ecotoxicological impact of environmental chemicals. |
2007-04-09 |
2023-08-12 |
Not clear |
| Mohammed Abul Kashem, Gabriel James, Clive Harper, Peter Wilce, Izuru Matsumot. Differential protein expression in the corpus callosum (splenium) of human alcoholics: a proteomics study. Neurochemistry international. vol 50. issue 2. 2007-03-30. PMID:17141922. |
our data also indicate the importance of other pathways including oxidative stress, lipid peroxidation and apoptosis as potential causes of alcohol-induced brain damage. |
2007-03-30 |
2023-08-12 |
human |
| Adriana Marquez, Saul Villa-Treviño, Françoise Guérau. The LEC rat: a useful model for studying liver carcinogenesis related to oxidative stress and inflammation. Redox report : communications in free radical research. vol 12. issue 1. 2007-03-23. PMID:17263906. |
lipid peroxidation products, such as malondialdehyde (mda) and 4-hydroxy-2-nonenal (hne), are closely related to carcinogenesis as they are potent mutagens and they have been suggested as modulators of signal pathways related to proliferation and apoptosis, two processes implicated in cancer development. |
2007-03-23 |
2023-08-12 |
human |
| Orhan Sen, Hakan Caner, M Volkan Aydin, Ozlem Ozen, Basar Atalay, Nur Altinors, Murad Bavbe. The effect of mexiletine on the level of lipid peroxidation and apoptosis of endothelium following experimental subarachnoid hemorrhage. Neurological research. vol 28. issue 8. 2007-03-21. PMID:17288746. |
the effect of mexiletine on the level of lipid peroxidation and apoptosis of endothelium following experimental subarachnoid hemorrhage. |
2007-03-21 |
2023-08-12 |
Not clear |
| Juliann G Kiang, K T Tse. Biology of hypoxia. The Chinese journal of physiology. vol 49. issue 5. 2007-03-20. PMID:17294830. |
hypoxia also increases intracellular ca2+ concentration, tumor necrosis factor-alpha, lipid peroxidation, prostaglandin e2 production, activity of caspase-3 and -9, and release of cytochrome c from mitochondria, apoptosis inducible factor, and endonuclease g. however, it has been shown that downregulation of inos can limit cell injury caused by hypoxia. |
2007-03-20 |
2023-08-12 |
Not clear |
| Vishal Chanana, Siddharth Majumdar, Praveen Rish. Involvement of caspase-3, lipid peroxidation and TNF-alpha in causing apoptosis of macrophages by coordinately expressed Salmonella phenotype under stress conditions. Molecular immunology. vol 44. issue 7. 2007-03-13. PMID:17027970. |
involvement of caspase-3, lipid peroxidation and tnf-alpha in causing apoptosis of macrophages by coordinately expressed salmonella phenotype under stress conditions. |
2007-03-13 |
2023-08-12 |
Not clear |
| Tsuyoshi Tsuzuki, Tomoko Kambe, Akira Shibata, Yuki Kawakami, Kiyotaka Nakagawa, Teruo Miyazaw. Conjugated EPA activates mutant p53 via lipid peroxidation and induces p53-dependent apoptosis in DLD-1 colorectal adenocarcinoma human cells. Biochimica et biophysica acta. vol 1771. issue 1. 2007-03-12. PMID:17196878. |
conjugated epa activates mutant p53 via lipid peroxidation and induces p53-dependent apoptosis in dld-1 colorectal adenocarcinoma human cells. |
2007-03-12 |
2023-08-12 |
human |
| Tsuyoshi Tsuzuki, Tomoko Kambe, Akira Shibata, Yuki Kawakami, Kiyotaka Nakagawa, Teruo Miyazaw. Conjugated EPA activates mutant p53 via lipid peroxidation and induces p53-dependent apoptosis in DLD-1 colorectal adenocarcinoma human cells. Biochimica et biophysica acta. vol 1771. issue 1. 2007-03-12. PMID:17196878. |
hence, we hypothesized that a combination of conjugated double bonds and an n-3 highly unsaturated fatty acid may produce a stronger antitumor effect, and we have previously shown that conjugated epa (cepa), prepared by alkaline treatment of epa, induces strong and selective apoptosis in vitro and in vivo, with the mechanism proceeding via lipid peroxidation. |
2007-03-12 |
2023-08-12 |
human |
| Tsuyoshi Tsuzuki, Tomoko Kambe, Akira Shibata, Yuki Kawakami, Kiyotaka Nakagawa, Teruo Miyazaw. Conjugated EPA activates mutant p53 via lipid peroxidation and induces p53-dependent apoptosis in DLD-1 colorectal adenocarcinoma human cells. Biochimica et biophysica acta. vol 1771. issue 1. 2007-03-12. PMID:17196878. |
in this study, we examined cepa-induced gene expression in dld-1 colorectal adenocarcinoma human cells carrying a mutant p53, in order to understand the details of cepa-induced apoptosis via lipid peroxidation. |
2007-03-12 |
2023-08-12 |
human |
| Tsuyoshi Tsuzuki, Tomoko Kambe, Akira Shibata, Yuki Kawakami, Kiyotaka Nakagawa, Teruo Miyazaw. Conjugated EPA activates mutant p53 via lipid peroxidation and induces p53-dependent apoptosis in DLD-1 colorectal adenocarcinoma human cells. Biochimica et biophysica acta. vol 1771. issue 1. 2007-03-12. PMID:17196878. |
this is the first such gene expression analysis of the effects of cepa, and our results confirm that cepa induces lipid peroxidation, activates mutant p53, and causes p53-dependent apoptosis in dld-1 cells. |
2007-03-12 |
2023-08-12 |
human |
| Hafiz Mohmmad Abdul, D Allan Butterfiel. Involvement of PI3K/PKG/ERK1/2 signaling pathways in cortical neurons to trigger protection by cotreatment of acetyl-L-carnitine and alpha-lipoic acid against HNE-mediated oxidative stress and neurotoxicity: implications for Alzheimer's disease. Free radical biology & medicine. vol 42. issue 3. 2007-03-12. PMID:17210450. |
pretreatment of primary cortical neuronal cultures with alcar and la significantly attenuated hne-induced cytotoxicity, protein oxidation, lipid peroxidation, and apoptosis in a dose-dependent manner. |
2007-03-12 |
2023-08-12 |
Not clear |
| Masaki Tanito, Sachiko Kaidzu, Robert E Anderso. Protective effects of soft acrylic yellow filter against blue light-induced retinal damage in rats. Experimental eye research. vol 83. issue 6. 2007-02-20. PMID:16997296. |
to assess retinal damage, the electroretinogram (erg) was recorded at 7 days, outer nuclear layer (onl) thickness and area were measured at 7 days, apoptosis was analyzed by tunel staining at 24 h, and the level of lipid peroxidation in retinas was assessed by western dot blots using specific antibodies against 4-hydroxynonenal (4-hne)- and carboxyethylpyrrole (cep)-modified proteins immediately after light exposure. |
2007-02-20 |
2023-08-12 |
rat |
| Fiorella Biasi, Barbara Vizio, Cinzia Mascia, Ezio Gaia, Neven Zarkovic, Elena Chiarpotto, Gabriella Leonarduzzi, Giuseppe Pol. c-Jun N-terminal kinase upregulation as a key event in the proapoptotic interaction between transforming growth factor-beta1 and 4-hydroxynonenal in colon mucosa. Free radical biology & medicine. vol 41. issue 3. 2007-02-15. PMID:16843825. |
another important cell growth inhibitor is the polyunsaturated lipid peroxidation end product, 4-hydroxynonenal (hne), which triggers apoptosis through c-jun n-terminal kinase (jnk) activation. |
2007-02-15 |
2023-08-12 |
human |
| Grzegorz A Czapski, Magdalena Cakala, Barbara Gajkowska, Joanna B Strosznajde. Poly(ADP-ribose) polymerase-1 inhibition protects the brain against systemic inflammation. Neurochemistry international. vol 49. issue 8. 2007-01-26. PMID:16904242. |
)-evoked systemic inflammation enhanced parp-1 activity in the mouse brain, leading to the lowering of beta-nad(+) concentration, to translocation of apoptosis inducing factor from mitochondria to the nucleus, and to enhanced lipid peroxidation. |
2007-01-26 |
2023-08-12 |
mouse |
| Fumiaki Beppu, Masashi Hosokawa, Leo Tanaka, Hiroyuki Kohno, Takuji Tanaka, Kazuo Miyashit. Potent inhibitory effect of trans9, trans11 isomer of conjugated linoleic acid on the growth of human colon cancer cells. The Journal of nutritional biochemistry. vol 17. issue 12. 2007-01-09. PMID:16563722. |
these results suggest that decreased expression of bcl-2 by t9t11-cla might increase the sensitivity of cells to lipid peroxidation and to programmed cell death, apoptosis. |
2007-01-09 |
2023-08-12 |
human |