| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Zhengyuan Xia, Min Liu, Yong Wu, Vijay Sharma, Tao Luo, Jingping Ouyang, John H McNeil. N-acetylcysteine attenuates TNF-alpha-induced human vascular endothelial cell apoptosis and restores eNOS expression. European journal of pharmacology. vol 550. issue 1-3. 2006-12-15. PMID:17026986. |
we investigated the effects of the antioxidant n-acetylcysteine on tnf-alpha-induced apoptosis in human vascular endothelial cell (cell line ecv304) apoptosis, no production and lipid peroxidation. |
2006-12-15 |
2023-08-12 |
human |
| Aluet Borrego, Zullyt Barbara Zamora, Ricardo González, Cheyla Romay, Silvia Menéndez, Frank Hernández, Jorge Berlanga, Teresita Monter. Ozone/oxygen mixture modifies the subcellular redistribution of Bax protein in renal tissue from rats treated with cisplatin. Archives of medical research. vol 37. issue 6. 2006-12-04. PMID:16824930. |
cellular events in cisplatin-mediated nephrotoxicity include apoptosis induction, decreased protein synthesis, changes in the subcellular redistribution of bax mitochondrial dysfunction, dna injury, increased lipid peroxidation, depletion of glutathione and decrease in enzymatic activity of renal antioxidant enzymes. |
2006-12-04 |
2023-08-12 |
rat |
| Marisela Olguín-Martínez, Edgar Mendieta-Condado, Martha Contreras-Zentella, José E Escamilla, Alberto Aranda-Fraustro, Mohammed El-Hafidi, Rolando Hernández-Muño. Rate of oxidant stress regulates balance between rat gastric mucosa proliferation and apoptosis. Free radical biology & medicine. vol 41. issue 8. 2006-11-20. PMID:17015179. |
after ethanol withdrawal, restitution of surface epithelium coincided with increased lipid peroxidation and cell proliferation and further active apoptosis. |
2006-11-20 |
2023-08-12 |
rat |
| Ji Young Lee, Geun Young Jung, Hye Jin Heo, Mi Ran Yun, Ji Young Park, Sun Sik Bae, Ki Whan Hong, Won Suk Lee, Chi Dae Ki. 4-Hydroxynonenal induces vascular smooth muscle cell apoptosis through mitochondrial generation of reactive oxygen species. Toxicology letters. vol 166. issue 3. 2006-11-14. PMID:16919899. |
4-hydroxynonenal (hne), an end-product of membrane lipid peroxidation, has been suggested to mediate a number of oxidative stress-linked pathological events such as cellular apoptosis. |
2006-11-14 |
2023-08-12 |
Not clear |
| Robert R Miller, Casey M Hay, Theodore R Striegnitz, Laura E Honsey, Carrie E Coykendall, Kevin D Blacquier. Exogenous glycine partially attenuates homocysteine-induced apoptosis and membrane peroxidation in chick embryos. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. vol 144. issue 1. 2006-11-07. PMID:16809069. |
the effects of exogenous glycine on homocysteine (hocys)-induced reductions in chick (gallus gallus) embryo viability, hocys-induced increases in brain and hepatic membrane lipid peroxidation, hocys-induced apoptosis (caspase-3 activities) in brain and hepatic tissues, and hocys-induced reductions in brain and hepatic s-adenosylemethionine (sam)/s-adenosylhomocysteine (sah) levels were studied. |
2006-11-07 |
2023-08-12 |
chicken |
| Mark A Lovell, William R Markesber. Amyloid beta peptide, 4-hydroxynonenal and apoptosis. Current Alzheimer research. vol 3. issue 4. 2006-11-03. PMID:17017866. |
although debated, increasing evidence suggests that oxidative stress/damage (amyloid beta peptide, iron/hydrogen peroxide) or neurotoxic by-products of lipid peroxidation (4-hydroxy-2-nonenal, acrolein) lead to cell death through apoptosis or programmed cell death in ad. |
2006-11-03 |
2023-08-12 |
Not clear |
| M Fu, M Wu, Y Qiao, Z Wan. Toxicological mechanisms of Aconitum alkaloids. Die Pharmazie. vol 61. issue 9. 2006-11-02. PMID:17020146. |
their toxicological mechanisms may involve interaction with voltage-dependent na+ channels, modulation of neurotransmitter release and related receptors, promotion of lipid peroxidation and induction of cell apoptosis in heart, liver or other organs. |
2006-11-02 |
2023-08-12 |
Not clear |
| Xiuqin Kong, Haitao Ge, Lijuan Hou, Limei Shi, Zhili Li. Induction of apoptosis in K562/ADM cells by gamma-linolenic acid involves lipid peroxidation and activation of caspase-3. Chemico-biological interactions. vol 162. issue 2. 2006-10-30. PMID:16857180. |
induction of apoptosis in k562/adm cells by gamma-linolenic acid involves lipid peroxidation and activation of caspase-3. |
2006-10-30 |
2023-08-12 |
Not clear |
| S Bondini, Z M Younoss. Non-alcoholic fatty liver disease and hepatitis C infection. Minerva gastroenterologica e dietologica. vol 52. issue 2. 2006-10-26. PMID:16557185. |
these factors include mediators of metabolic syndrome such as adipokines, inflammatory cytokines, factors associated with oxidative stress, lipid peroxidation products, as well as apoptosis and hepatic stellate cell activation with the resultant deposition of extracellular matrix. |
2006-10-26 |
2023-08-12 |
Not clear |
| Manuchair Ebadi, Sushil Sharm. Metallothioneins 1 and 2 attenuate peroxynitrite-induced oxidative stress in Parkinson disease. Experimental biology and medicine (Maywood, N.J.). vol 231. issue 9. 2006-10-25. PMID:17018883. |
sin-1-induced lipid peroxidation, reactive oxygen species synthesis, caspase-3 activation, and apoptosis were attenuated by metallothionein gene overexpression and augmented by metallothionein gene down-regulation. |
2006-10-25 |
2023-08-12 |
mouse |
| Ting Wu, Xin-Sheng Ding, Wei Wang, Jin W. MCI-186 (3-methyl-1-phenyl-2-pyrazolin-5-one) attenuated simulated ischemia/reperfusion injury in cultured rat hippocampal cells. Biological & pharmaceutical bulletin. vol 29. issue 8. 2006-10-18. PMID:16880614. |
mci-186 effectively protects neuron injury after simulated ischemia/reperfusion by inhibiting lipid peroxidation, reducing ca2+ overload, elevating mitochondria membrane potential, and decreasing apoptosis. |
2006-10-18 |
2023-08-12 |
rat |
| C Bouaziz, S Abid-Essefi, A Bouslimi, E El Golli, H Bach. Cytotoxicity and related effects of T-2 toxin on cultured Vero cells. Toxicon : official journal of the International Society on Toxinology. vol 48. issue 3. 2006-10-18. PMID:16884754. |
in this study, cytotoxicity and apotosis induction by t-2 toxin was investigated in vitro on vero cell line using the mtt and the neutral red viability assays, the induction of lipid peroxidation, the decrease of macromolecule levels (protein, dna and rna), dna fragmentation and caspase-3-dependent apoptosis induction. |
2006-10-18 |
2023-08-12 |
human |
| K Bhatia, M Kaur, F Atif, M Ali, H Rehman, S Rahman, S Raisuddi. Aqueous extract of Trigonella foenum-graecum L. ameliorates additive urotoxicity of buthionine sulfoximine and cyclophosphamide in mice. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 44. issue 10. 2006-10-05. PMID:16828947. |
restoration of gsh by extract treatment may play an important role in reversing cp-induced apoptosis and free radical-mediated lpo in urinary bladder. |
2006-10-05 |
2023-08-12 |
mouse |
| Abha Sharma, Brad Patrick, Jie Li, Rajendra Sharma, Prince V S Jeyabal, Prasada M R V Reddy, Sanjay Awasthi, Yogesh C Awasth. Glutathione S-transferases as antioxidant enzymes: small cell lung cancer (H69) cells transfected with hGSTA1 resist doxorubicin-induced apoptosis. Archives of biochemistry and biophysics. vol 452. issue 2. 2006-09-26. PMID:16890185. |
in order to examine the protective role of alpha-class gst isozyme hgsta1-1 against doxorubicin (dox)-induced lipid peroxidation, cytotoxicity, and apoptosis, human small cell lung cancer (sclc) h69 cells were stably transfected with hgsta1. |
2006-09-26 |
2023-08-12 |
human |
| Abha Sharma, Brad Patrick, Jie Li, Rajendra Sharma, Prince V S Jeyabal, Prasada M R V Reddy, Sanjay Awasthi, Yogesh C Awasth. Glutathione S-transferases as antioxidant enzymes: small cell lung cancer (H69) cells transfected with hGSTA1 resist doxorubicin-induced apoptosis. Archives of biochemistry and biophysics. vol 452. issue 2. 2006-09-26. PMID:16890185. |
these results are consistent with the idea that the alpha-class gsts provide protection against oxidative stress by attenuating lipid peroxidation and these enzymes can modulate signaling for apoptosis. |
2006-09-26 |
2023-08-12 |
human |
| b' E Grosicka, B Sadurska, M Szumi\\xc5\\x82o, T Grzela, P \\xc5\\x81azarczyk, J Niderla-Bieli\\xc5\\x84ska, I Rahden-Staro\\xc5\\x8. Effect of glutathione depletion on apoptosis induced by thiram in Chinese hamster fibroblasts. International immunopharmacology. vol 5. issue 13-14. 2006-09-22. PMID:16275629.' |
the concentrations of thiram required to induce cellular gsh depletion (by 40-50%), protein, and membrane lipid peroxidation (2-fold, and 1.7-fold, respectively), as well as to induce apoptosis in v79 chinese hamster fibroblasts without causing necrosis through cytotoxic effects were between 50-100 microm. |
2006-09-22 |
2023-08-12 |
Not clear |
| Hafiz Mohmmad Abdul, Vittorio Calabrese, Menotti Calvani, D Allan Butterfiel. Acetyl-L-carnitine-induced up-regulation of heat shock proteins protects cortical neurons against amyloid-beta peptide 1-42-mediated oxidative stress and neurotoxicity: implications for Alzheimer's disease. Journal of neuroscience research. vol 84. issue 2. 2006-09-19. PMID:16634066. |
pretreatment of primary cortical neuronal cultures with alcar significantly attenuated abeta(1-42)-induced cytotoxicity, protein oxidation, lipid peroxidation, and apoptosis in a dose-dependent manner. |
2006-09-19 |
2023-08-12 |
rat |
| Chuang C Chiueh, Tsugunobu Andoh, P Boon Choc. Induction of thioredoxin and mitochondrial survival proteins mediates preconditioning-induced cardioprotection and neuroprotection. Annals of the New York Academy of Sciences. vol 1042. 2006-09-11. PMID:15965087. |
cytosolic trx1 and mitochondrial trx2 suppress free radical formation, lipid peroxidation, oxidative stress, and mitochondria-dependent apoptosis; knock out/down of either trx1 or trx2 is detrimental to cell survival. |
2006-09-11 |
2023-08-12 |
mouse |
| V V Novitskii, A K Strelis, S B Tkachenko, I E Esimova, T A Shil'ko, O I Urazova, O V Voronkova, V A Sinitsina, O V Filinyuk, N A Zemlyanay. LPO and apoptosis during pulmonary tuberculosis. Bulletin of experimental biology and medicine. vol 140. issue 5. 2006-09-11. PMID:16758605. |
lpo and apoptosis during pulmonary tuberculosis. |
2006-09-11 |
2023-08-12 |
Not clear |
| V V Novitskii, A K Strelis, S B Tkachenko, I E Esimova, T A Shil'ko, O I Urazova, O V Voronkova, V A Sinitsina, O V Filinyuk, N A Zemlyanay. LPO and apoptosis during pulmonary tuberculosis. Bulletin of experimental biology and medicine. vol 140. issue 5. 2006-09-11. PMID:16758605. |
lpo and apoptosis in blood mononuclear cells were studied in patients with pulmonary tuberculosis before and during treatment with standard chemotherapeutics. |
2006-09-11 |
2023-08-12 |
Not clear |