| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Tiziana Genovese, Emanuela Mazzon, Emanuela Esposito, Carmelo Muià, Rosanna Di Paola, Paolo Di Bella, Placido Bramanti, Salvatore Cuzzocre. Role of endogenous glutathione in the secondary damage in experimental spinal cord injury in mice. Neuroscience letters. vol 423. issue 1. 2007-12-03. PMID:17669594. |
the spinal cord of damaged animals showed a significant elevation of biochemical, immunohistochemical and functional parameters, increasing, respectively, neutrophils infiltration, lipid peroxidation, nitrotyrosine formation, par expression, apoptosis (measured by tunel staining) and loss of hind legs movement in sci-operated mice. |
2007-12-03 |
2023-08-12 |
mouse |
| Tiziana Genovese, Emanuela Mazzon, Emanuela Esposito, Carmelo Muià, Rosanna Di Paola, Paolo Di Bella, Placido Bramanti, Salvatore Cuzzocre. Role of endogenous glutathione in the secondary damage in experimental spinal cord injury in mice. Neuroscience letters. vol 423. issue 1. 2007-12-03. PMID:17669594. |
in contrast, the administration of bso led to worsening of this already compromised setting, increasing the degree of (1) neutrophil infiltration, (2) lipid peroxidation, (3) histological damage, (4) apoptosis, (5) nitrotyrosine formation, (6) par expression, (7) apoptosis (measured by tunel staining) and (7) loss of hind legs movement. |
2007-12-03 |
2023-08-12 |
mouse |
| Ubaldo Bonuccelli, Nicola Paves. Role of dopamine agonists in Parkinson's disease: an update. Expert review of neurotherapeutics. vol 7. issue 10. 2007-11-29. PMID:17939774. |
this neuroprotection may be the result of different mechanisms including antioxidation, scavenging of free radicals, suppression of lipid peroxidation and inhibition of apoptosis. |
2007-11-29 |
2023-08-12 |
Not clear |
| Yoshiji Ohta, Sayaka Chiba, Masayo Tada, Yoichiro Imai, Akira Kitagaw. Development of oxidative stress and cell damage in the liver of rats with water-immersion restraint stress. Redox report : communications in free radical research. vol 12. issue 3. 2007-11-13. PMID:17623521. |
in the liver tissue, vacuolization and apoptosis occurred at 1.5 h of wirs and vacuolization further developed without further appearance of apoptosis at 3 h or 6 h. serum lipid peroxide (lpo) and nox (nitrite/nitrate) concentrations increased at 3 h of wirs and these increases were enhanced at 6 h. in liver tissue, increases in lpo and nox concentrations and myeloperoxidase activity and decreases in ascorbic acid and reduced glutathione concentrations and superoxide dismutase activity occurred at 3 h of wirs and these changes were enhanced at 6 h, although vitamin e concentration and xanthine oxidase activity were unchanged. |
2007-11-13 |
2023-08-12 |
rat |
| Xiang-lin Chi, Zhen-guang Li, Zhao-rong Guo, Li Zhou, Hong-hao Man, Chun-yu Dong, Ke-ping B. [Progress of studies on the mechanism of acupuncture treatment of acute ischemic cerebral stroke]. Zhen ci yan jiu = Acupuncture research. vol 32. issue 4. 2007-10-17. PMID:17907396. |
in the present paper, the authors review the current development of studies on mechanisms of acupuncture treatment of acute ischemic cerebral apoplexy from (1) blood rheology, (2) cerebral microcirculation, 3) metabolism of cerebral tissue, (4) cerebral electrical activity, (5) free radicals and lipid peroxidation reaction, (6) excitatory aminoacid, (7) calcium overload, (8) nitrogen monoxidum, and (9) cerebral apoptosis. |
2007-10-17 |
2023-08-12 |
Not clear |
| Lisa C Hutton, Margie Castillo-Melendez, David W Walke. Uteroplacental inflammation results in blood brain barrier breakdown, increased activated caspase 3 and lipid peroxidation in the late gestation ovine fetal cerebellum. Developmental neuroscience. vol 29. issue 4-5. 2007-10-05. PMID:17762202. |
placental lipopolysaccharide treatment had substantial effects on the fetal cerebellum, including increasing the number of cells undergoing apoptosis, widespread lipid peroxidation, and extravasation of plasma albumin, suggesting compromise of the cerebellar blood-brain barrier. |
2007-10-05 |
2023-08-12 |
Not clear |
| Eitan Okun, Thiruma V Arumugam, Sung-Chun Tang, Marc Gleichmann, Michael Albeck, Benjamin Sredni, Mark P Mattso. The organotellurium compound ammonium trichloro(dioxoethylene-0,0') tellurate enhances neuronal survival and improves functional outcome in an ischemic stroke model in mice. Journal of neurochemistry. vol 102. issue 4. 2007-10-04. PMID:17542809. |
studies of cultured neurons showed that as101 confers protection against apoptosis induced by either glucose deprivation or the lipid peroxidation product 4-hydroxynonenal. |
2007-10-04 |
2023-08-12 |
mouse |
| Maurizio Moretti, Carlo Felice Marchion. An overview of erdosteine antioxidant activity in experimental research. Pharmacological research. vol 55. issue 4. 2007-08-29. PMID:17267240. |
the final result is a protective effect on tissues which reduces lipid peroxidation, neutrophil infiltration or cell apoptosis mediated by noxious agents. |
2007-08-29 |
2023-08-12 |
Not clear |
| Jun Re. Influence of gender on oxidative stress, lipid peroxidation, protein damage and apoptosis in hearts and brains from spontaneously hypertensive rats. Clinical and experimental pharmacology & physiology. vol 34. issue 5-6. 2007-08-15. PMID:17439412. |
influence of gender on oxidative stress, lipid peroxidation, protein damage and apoptosis in hearts and brains from spontaneously hypertensive rats. |
2007-08-15 |
2023-08-12 |
rat |
| Jun Re. Influence of gender on oxidative stress, lipid peroxidation, protein damage and apoptosis in hearts and brains from spontaneously hypertensive rats. Clinical and experimental pharmacology & physiology. vol 34. issue 5-6. 2007-08-15. PMID:17439412. |
oxidative stress, lipid peroxidation, protein damage and apoptosis were assessed by glutathione (gsh) : reduced glutathione (gssg) ratio, malondialdehyde (mda) levels, protein carbonyl levels and caspase-3 activity, respectively. |
2007-08-15 |
2023-08-12 |
rat |
| F Filipak Neto, S M Zanata, H C Silva de Assis, D Bussolaro, M V M Ferraro, M A F Randi, J R M Alves Costa, M M Cestari, H Roche, C A Oliveira Ribeir. Use of hepatocytes from Hoplias malabaricus to characterize the toxicity of a complex mixture of lipophilic halogenated compounds. Toxicology in vitro : an international journal published in association with BIBRA. vol 21. issue 4. 2007-08-06. PMID:17293077. |
the dmso at 0.1% increased the lipid peroxidation, gsh concentration, apoptosis and dna damage. |
2007-08-06 |
2023-08-12 |
Not clear |
| Myoungsook Lee, Myung-Ae Ba. Docosahexaenoic acid induces apoptosis in CYP2E1-containing HepG2 cells by activating the c-Jun N-terminal protein kinase related mitochondrial damage. The Journal of nutritional biochemistry. vol 18. issue 5. 2007-07-20. PMID:16963249. |
our results indicated that dha-mediated apoptosis in e47 cells was induced through the activation of the jnk-related cell death pathway, which may be involved in the production of lpo or reactive oxygen species during the cyp2e1 catalytic cycle, followed by mitochondrial injury and apoptosis. |
2007-07-20 |
2023-08-12 |
human |
| Steven T S Lim, Klaus Dragull, Chung-Shih Tang, Harry C Bittenbender, Jimmy T Efird, Pratibha V Nerurka. Effects of kava alkaloid, pipermethystine, and kavalactones on oxidative stress and cytochrome P450 in F-344 rats. Toxicological sciences : an official journal of the Society of Toxicology. vol 97. issue 1. 2007-07-03. PMID:17329236. |
treatment of f-344 rats with pm (10 mg/kg) and kre (100 mg/kg) for 2 weeks failed to elicit any significant changes in liver function tests or cause severe hepatic toxicity as measured by lipid peroxidation and apoptosis markers such as malondialdehyde, bax, and bcl-2. |
2007-07-03 |
2023-08-12 |
human |
| Angelo Cerbone, Cristina Toaldo, Stefano Laurora, Federica Briatore, Stefania Pizzimenti, Mario U Dianzani, Carlo Ferretti, Giuseppina Barrer. 4-Hydroxynonenal and PPARgamma ligands affect proliferation, differentiation, and apoptosis in colon cancer cells. Free radical biology & medicine. vol 42. issue 11. 2007-06-19. PMID:17462534. |
4-hydroxynonenal (hne), a product of lipid peroxidation, inhibits proliferation and induces differentiation or apoptosis in neoplastic cells. |
2007-06-19 |
2023-08-12 |
Not clear |
| M Li, Z M Kong, Z L Li. Antioxidant enzyme activities and lipid peroxidation induced by eicosapentaenoic acid (EPA) in PC12 cells. Cell biology and toxicology. vol 22. issue 5. 2007-06-07. PMID:16847743. |
in this study, the epa induced lipid peroxidation and response of antioxidative enzymes have been investigated in rat pheochromocytoma pc12 cells to elucidate the mechanisms of apoptosis induced by the polyunsaturated fatty acid epa. |
2007-06-07 |
2023-08-12 |
rat |
| M Li, Z M Kong, Z L Li. Antioxidant enzyme activities and lipid peroxidation induced by eicosapentaenoic acid (EPA) in PC12 cells. Cell biology and toxicology. vol 22. issue 5. 2007-06-07. PMID:16847743. |
the results suggest that in pc12 cells the mechanism of apoptosis induced by epa may be partly due to lipid peroxidation. |
2007-06-07 |
2023-08-12 |
rat |
| Manuela Gago-Dominguez, Xuejuan Jiang, J Esteban Castela. Lipid peroxidation and the protective effect of physical exercise on breast cancer. Medical hypotheses. vol 68. issue 5. 2007-06-06. PMID:17113718. |
specifically, we describe (1) the sources of free radicals occurring during exercise, (2) existing experimental data on physical exercise, lipid peroxidation and cancer, (3) existing supporting data implicating exercise-induced reactive oxygen species (ros) as the mechanism responsible for increased apoptosis in different cell systems, and (4) changes in the antioxidant enzymes glutathione s transferases (gsts), superoxide dismutase (sod), glutathione peroxidase (gpx), and catalase (cat) that occur after physical exercise, which are believed to be a physiologic response to oxidative stress induced by physical exercise. |
2007-06-06 |
2023-08-12 |
cat |
| Yoshisuke Haruna, Naoki Kashihara, Minoru Satoh, Naruya Tomita, Tamehachi Namikoshi, Tamaki Sasaki, Toshihiko Fujimori, Ping Xie, Yashpal S Kanwa. Amelioration of progressive renal injury by genetic manipulation of Klotho gene. Proceedings of the National Academy of Sciences of the United States of America. vol 104. issue 7. 2007-05-17. PMID:17287345. |
this improvement was associated with dramatic improvement in renal functions, morphological lesions, and cytochrome c oxidase activity but a reduction in beta-galactosidase activity (a senescence-associated protein), mitochondrial dna fragmentation, superoxide anion generation, lipid peroxidation, and bax protein expression and apoptosis. |
2007-05-17 |
2023-08-12 |
mouse |
| Rogéria C Mund, Nathalia Pizato, Sandro Bonatto, Everson A Nunes, Thiago Vicenzi, Ricardo Tanhoffer, Heloisa H P de Oliveira, Rui Curi, Philip C Calder, Luiz C Fernande. Decreased tumor growth in Walker 256 tumor-bearing rats chronically supplemented with fish oil involves COX-2 and PGE2 reduction associated with apoptosis and increased peroxidation. Prostaglandins, leukotrienes, and essential fatty acids. vol 76. issue 2. 2007-05-09. PMID:17234396. |
these results suggest that reduction of tumor growth by fo involves an increase in apoptosis and of lipid peroxidation in tumor tissue, with a reduction in tumor cell proliferation ex vivo, cox-2 expression and pge2 production. |
2007-05-09 |
2023-08-12 |
rat |
| Marzena Podhorska-Okolow, Piotr Dziegiel, Eugenia Murawska-Cialowicz, Jolanta Saczko, Julita Kulbacka, Agnieszka Gomulkiewicz, Katia Rossini, Zbigniew Jethon, Ugo Carraro, Maciej Zabe. Effects of adaptive exercise on apoptosis in cells of rat renal tubuli. European journal of applied physiology. vol 99. issue 3. 2007-04-20. PMID:17102979. |
we measured apoptosis, expression of at1 and at2 receptors, level of lipid peroxidation (tbars) and activities of antioxidant enzymes, sod, gpx and cat in kidneys of sedentary rats that were exposed to acute exercise and rats that were trained for 8 weeks. |
2007-04-20 |
2023-08-12 |
rat |