Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Zhanqing Li, Arash Nickkholgh, Xue Yi, Helge Bruns, Marie-Luise Gross, Katrin Hoffmann, Elvira Mohr, Markus Zorn, Markus W Büchler, Peter Schemme. Melatonin protects kidney grafts from ischemia/reperfusion injury through inhibition of NF-kB and apoptosis after experimental kidney transplantation. Journal of pineal research. vol 46. issue 4. 2009-09-17. PMID:19552759. |
biopsies were taken to evaluate tubular damage, the enzymatic activity of superoxide dismutase (sod) and lipid hydroperoxide (lpo), and the expression of nf-kbp65, inducible nitric oxide synthase (inos), caspase-3 as indices of oxidative stress, necrosis, and apoptosis, respectively. |
2009-09-17 |
2023-08-12 |
rat |
Adem Aslan, Mustafa Cemek, Olcay Eser, Korhan Altunbaş, Mehmet Emin Buyukokuroglu, Murat Cosar, Orhan Baş, Yuksel Ela, Huseyin Fida. Does dexmedetomidine reduce secondary damage after spinal cord injury? An experimental study. European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society. vol 18. issue 3. 2009-09-15. PMID:19130093. |
dex treatment slightly prevented lipid peroxidation and augmented endogenous antioxidative defense systems in csf or spinal cord tissue, but failed to prevent apoptosis or neurodeficit after traumatic sci. |
2009-09-15 |
2023-08-12 |
Not clear |
Ozgur Kutuk, Elif Damla Arisan, Tugsan Tezil, Maria C Shoshan, Huveyda Basag. Cisplatin overcomes Bcl-2-mediated resistance to apoptosis via preferential engagement of Bak: critical role of Noxa-mediated lipid peroxidation. Carcinogenesis. vol 30. issue 9. 2009-09-15. PMID:19578044. |
cisplatin overcomes bcl-2-mediated resistance to apoptosis via preferential engagement of bak: critical role of noxa-mediated lipid peroxidation. |
2009-09-15 |
2023-08-12 |
Not clear |
Ozgur Kutuk, Elif Damla Arisan, Tugsan Tezil, Maria C Shoshan, Huveyda Basag. Cisplatin overcomes Bcl-2-mediated resistance to apoptosis via preferential engagement of Bak: critical role of Noxa-mediated lipid peroxidation. Carcinogenesis. vol 30. issue 9. 2009-09-15. PMID:19578044. |
in conclusion, our findings suggest a novel mode of action for cisplatin to overcome bcl-2-mediated protection against apoptosis, which requires preferential activation of bak and p53-mediated upregulation of noxa protein levels and lipid peroxidation. |
2009-09-15 |
2023-08-12 |
Not clear |
Larry Siu, Julie Foont, Jack R Wand. Hepatitis C virus and alcohol. Seminars in liver disease. vol 29. issue 2. 2009-09-08. PMID:19387918. |
some of the major postulated mechanisms responsible for disease progression include high rates of apoptosis, lipid peroxidation, and generation of free radicals and reactive oxygen species with reduced antioxidant capacity of the liver. |
2009-09-08 |
2023-08-12 |
Not clear |
Stephen J Wood, Murat Yücel, Christos Pantelis, Michael Ber. Neurobiology of schizophrenia spectrum disorders: the role of oxidative stress. Annals of the Academy of Medicine, Singapore. vol 38. issue 5. 2009-09-03. PMID:19521638. |
this is reflected by evidence of the manifold consequences of oxidative stress that include lipid peroxidation, protein carboxylation, dna damage and apoptosis - all potentially part of the process of neuroprogression in the disorder. |
2009-09-03 |
2023-08-12 |
Not clear |
Jinu Kim, Young Mi Seok, Kyong-Jin Jung, Kwon Moo Par. Reactive oxygen species/oxidative stress contributes to progression of kidney fibrosis following transient ischemic injury in mice. American journal of physiology. Renal physiology. vol 297. issue 2. 2009-08-27. PMID:19458120. |
i/r significantly increased interstitial extension, collagen deposition, apoptosis of tubular epithelial cells, nitrotyrosine expression, hydrogen peroxide production, and lipid peroxidation and decreased copper-zinc sod, manganese sod, and glucose 6-phosphate dehydrogenase activities in the kidneys 16 days after the procedure. |
2009-08-27 |
2023-08-12 |
mouse |
Benedicto Oscar Colli, Daniela Pretti da Cunha Tirapelli, Carlos Gilberto Carlotti, Luiza da Silva Lopes, Luis Fernando Tirapell. Biochemical evaluation of focal non-reperfusion cerebral ischemia by middle cerebral artery occlusion in rats. Arquivos de neuro-psiquiatria. vol 66. issue 3B. 2009-08-19. PMID:18949271. |
despite significant changes in atp levels, the results indicated cell viability in the ischemic region as shown by the low rates of lipid peroxidation and apoptosis, findings probably related to the lack of reperfusion. |
2009-08-19 |
2023-08-12 |
human |
Burton M Altura, Nilank C Shah, Xian-Cheng Jiang, Zhiqiang Li, José Luis Perez-Albela, Anthony C Sica, Bella T Altur. Short-term magnesium deficiency results in decreased levels of serum sphingomyelin, lipid peroxidation, and apoptosis in cardiovascular tissues. American journal of physiology. Heart and circulatory physiology. vol 297. issue 1. 2009-08-12. PMID:19429813. |
short-term magnesium deficiency results in decreased levels of serum sphingomyelin, lipid peroxidation, and apoptosis in cardiovascular tissues. |
2009-08-12 |
2023-08-12 |
rat |
Mubeen Ahmad Ansari, Hafiz Mohammad Abdul, Gururaj Joshi, Wycliffe O Opii, D Allan Butterfiel. Protective effect of quercetin in primary neurons against Abeta(1-42): relevance to Alzheimer's disease. The Journal of nutritional biochemistry. vol 20. issue 4. 2009-07-24. PMID:18602817. |
pretreatment of primary hippocampal cultures with quercetin significantly attenuated abeta(1-42)-induced cytotoxicity, protein oxidation, lipid peroxidation and apoptosis. |
2009-07-24 |
2023-08-12 |
Not clear |
P Tessari, A Coracina, A Cosma, A Tieng. Hepatic lipid metabolism and non-alcoholic fatty liver disease. Nutrition, metabolism, and cardiovascular diseases : NMCD. vol 19. issue 4. 2009-07-23. PMID:19359149. |
the latter likely involves oxidative stress, cytochrome p450 activation, lipid peroxidation, increased inflammatory cytokine production, activation of hepatic stellate cells and apoptosis. |
2009-07-23 |
2023-08-12 |
Not clear |
Asser I Ghonei. Effects of curcumin on ethanol-induced hepatocyte necrosis and apoptosis: implication of lipid peroxidation and cytochrome c. Naunyn-Schmiedeberg's archives of pharmacology. vol 379. issue 1. 2009-07-14. PMID:18716759. |
effects of curcumin on ethanol-induced hepatocyte necrosis and apoptosis: implication of lipid peroxidation and cytochrome c. ethanol-induced hepatocyte necrosis and apoptosis are valid in vitro models to investigate the modulatory effects of hepatoprotective/toxic agents such as curcumin. |
2009-07-14 |
2023-08-12 |
rat |
Charitha Gangadharan, Maikho Thoh, Sunil K Mann. Inhibition of constitutive activity of nuclear transcription factor kappaB sensitizes doxorubicin-resistant cells to apoptosis. Journal of cellular biochemistry. vol 107. issue 2. 2009-07-14. PMID:19242952. |
moreover, in resistant cells doxorubicin was unable to induce apoptosis as detected by assays for reactive oxygen intermediates generation, lipid peroxidation, cytotoxicity, parp degradation and bcl-2 expression. |
2009-07-14 |
2023-08-12 |
Not clear |
Haitao Ge, Xiuqin Kong, Limei Shi, Lijuan Hou, Zhili Liu, Ping L. Gamma-linolenic acid induces apoptosis and lipid peroxidation in human chronic myelogenous leukemia K562 cells. Cell biology international. vol 33. issue 3. 2009-07-13. PMID:19356705. |
gamma-linolenic acid induces apoptosis and lipid peroxidation in human chronic myelogenous leukemia k562 cells. |
2009-07-13 |
2023-08-12 |
human |
K Hyakkoku, Y Nakajima, H Izuta, M Shimazawa, T Yamamoto, N Shibata, H Har. Thalidomide protects against ischemic neuronal damage induced by focal cerebral ischemia in mice. Neuroscience. vol 159. issue 2. 2009-06-17. PMID:19166916. |
brains were also histochemically assessed for apoptosis and lipid peroxidation using terminal deoxynucleotidyl transferase-mediated dutp nick end-labeling (tunel) staining and an antibody recognizing 8-hydroxy-2'-deoxyguanosine (8-ohdg), respectively. |
2009-06-17 |
2023-08-12 |
mouse |
Xiang-Chun Shen, Zhi-Yu Qian, Ya-Juan Wang, Jin-Ao Dua. Crocetin attenuates norepinephrine-induced cytotoxicity in primary cultured rat cardiac myocytes by antioxidant in vitro. Journal of Asian natural products research. vol 11. issue 5. 2009-06-17. PMID:19504384. |
the results showed that crocetin may ameliorate ne-induced injury in cardiac myocytes by enhanced sod activity and increased quantities of gsh, decreased lipid peroxidation and ca(2+) in cells, and apoptosis death ratio that may represent the cellular mechanisms for its cardioprotective role. |
2009-06-17 |
2023-08-12 |
rat |
K L Khanduja, S Kumar, N Varma, S C Varma, P K Avti, C M Patha. Enhancement in alpha-tocopherol succinate-induced apoptosis by all-trans-retinoic acid in primary leukemic cells: role of antioxidant defense, Bax and c-myc. Molecular and cellular biochemistry. vol 319. issue 1-2. 2009-06-16. PMID:18642056. |
in conclusion, the data reveal that enhancement of alpha-ts-induced apoptosis by atra in leukemic cells was through up regulation of bax and lipid peroxidation, and down regulation of c-myc and gsh. |
2009-06-16 |
2023-08-12 |
Not clear |
S Matsuda, M Umeda, H Uchida, H Kato, Tsutomu Arak. Alterations of oxidative stress markers and apoptosis markers in the striatum after transient focal cerebral ischemia in rats. Journal of neural transmission (Vienna, Austria : 1996). vol 116. issue 4. 2009-06-09. PMID:19238518. |
the present results also suggest that increased reactive oxygen species (ros) production during reperfusion may contribute to the induction of the alteration of lipid peroxidation and could thereby lead to apoptosis in neurons of the ipsilateral striatum after transient focal ischemia, because of an insufficient expression of cu/zn-sod and mn-sod. |
2009-06-09 |
2023-08-12 |
rat |
S Matsuda, M Umeda, H Uchida, H Kato, Tsutomu Arak. Alterations of oxidative stress markers and apoptosis markers in the striatum after transient focal cerebral ischemia in rats. Journal of neural transmission (Vienna, Austria : 1996). vol 116. issue 4. 2009-06-09. PMID:19238518. |
furthermore, our findings demonstrate that the lipid peroxidation against mitochondrial membrane may contribute to apoptosis of striatal neurons after transient focal ischemia. |
2009-06-09 |
2023-08-12 |
rat |
Am Domijan, D Zeljezic, M Peraica, G Kovacevic, G Gregorovic, Z Krstanac, K Horvatin, M Kalafati. Early toxic effects of fumonisin B1 in rat liver. Human & experimental toxicology. vol 27. issue 12. 2009-06-02. PMID:19273544. |
it is known that long-term exposure of experimental animals to fb(1) causes apoptosis and lipid peroxidation. |
2009-06-02 |
2023-08-12 |
rat |