| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ghaffar Shokouhi, R Shane Tubbs, Mohammadali M Shoja, Leila Roshangar, Mehran Mesgari, Amir Ghorbanihaghjo, Naser Ahmadi, Farzam Sheikhzadeh, Jafar S Ra. The effects of aerobic exercise training on the age-related lipid peroxidation, Schwann cell apoptosis and ultrastructural changes in the sciatic nerve of rats. Life sciences. vol 82. issue 15-16. 2008-06-17. PMID:18336840. |
we examined the effects of long-term aerobic exercise training on lipid peroxidation, schwann cell (sc) apoptosis and ultrastructural changes in the sciatic nerve of rats during aging. |
2008-06-17 |
2023-08-12 |
rat |
| Ghaffar Shokouhi, R Shane Tubbs, Mohammadali M Shoja, Leila Roshangar, Mehran Mesgari, Amir Ghorbanihaghjo, Naser Ahmadi, Farzam Sheikhzadeh, Jafar S Ra. The effects of aerobic exercise training on the age-related lipid peroxidation, Schwann cell apoptosis and ultrastructural changes in the sciatic nerve of rats. Life sciences. vol 82. issue 15-16. 2008-06-17. PMID:18336840. |
the results showed that aging was associated with an increased level of nerve malondialdehyde (mda, marker of lipid peroxidation) and a higher number of sc apoptosis in sed group. |
2008-06-17 |
2023-08-12 |
rat |
| Ghaffar Shokouhi, R Shane Tubbs, Mohammadali M Shoja, Leila Roshangar, Mehran Mesgari, Amir Ghorbanihaghjo, Naser Ahmadi, Farzam Sheikhzadeh, Jafar S Ra. The effects of aerobic exercise training on the age-related lipid peroxidation, Schwann cell apoptosis and ultrastructural changes in the sciatic nerve of rats. Life sciences. vol 82. issue 15-16. 2008-06-17. PMID:18336840. |
however, the et group had significantly diminished nerve lipid peroxidation and sc apoptosis. |
2008-06-17 |
2023-08-12 |
rat |
| Maria Pia Rigobello, Alessandra Folda, Barbara Dani, Roberta Menabò, Guido Scutari, Alberto Bindol. Gold(I) complexes determine apoptosis with limited oxidative stress in Jurkat T cells. European journal of pharmacology. vol 582. issue 1-3. 2008-06-05. PMID:18242600. |
these results demonstrate that the increased production of hydrogen peroxide determines an oxidative shift responsible for the occurrence of apoptosis and not involving lipid peroxidation. |
2008-06-05 |
2023-08-12 |
Not clear |
| Richard C Li, Matthew W Morris, Seung Kwan Lee, Farzan Pouranfar, Yang Wang, David Goza. Neuroglobin protects PC12 cells against oxidative stress. Brain research. vol 1190. 2008-05-06. PMID:18083144. |
overexpression of wild type ngb, but not of mutant ngb, significantly attenuated h2o2-induced ros/rns accumulation and lipid peroxidation, decreased h2o2-induced mitochondrial dysfunction and apoptosis, and promoted overall cell survival. |
2008-05-06 |
2023-08-12 |
Not clear |
| J Finstere. Is atherosclerosis a mitochondrial disorder? VASA. Zeitschrift fur Gefasskrankheiten. vol 36. issue 4. 2008-04-30. PMID:18357915. |
oxidative stress results in lipid peroxidation, damage of mitochondrial components including mitochondrial dna, mitochondrial dysfunction, damage of endothelial cells, vascular smooth muscle cells, and erythrocytes, and lastly apoptosis via either the receptor-mediated pathway or the mitochondria-mediated pathway and activation of the caspase cascade. |
2008-04-30 |
2023-08-12 |
Not clear |
| Miranda L Bader Lange, Giovanna Cenini, Marta Piroddi, Hafiz Mohmmad Abdul, Rukhsana Sultana, Francesco Galli, Maurizio Memo, D Allan Butterfiel. Loss of phospholipid asymmetry and elevated brain apoptotic protein levels in subjects with amnestic mild cognitive impairment and Alzheimer disease. Neurobiology of disease. vol 29. issue 3. 2008-04-28. PMID:18077176. |
oxidative stress, a hallmark of alzheimer disease (ad), has been shown to induce lipid peroxidation and apoptosis disrupting cellular homeostasis. |
2008-04-28 |
2023-08-12 |
human |
| Rui Maeda, Eisei Noiri, Hiroyuki Isobe, Tatsuya Homma, Tamami Tanaka, Kousuke Negishi, Kent Doi, Toshiro Fujita, Eiichi Nakamur. A water-soluble fullerene vesicle alleviates angiotensin II-induced oxidative stress in human umbilical venous endothelial cells. Hypertension research : official journal of the Japanese Society of Hypertension. vol 31. issue 1. 2008-04-15. PMID:18360029. |
the phk decreased the aii-induced apoptosis and lipid peroxidation processes as revealed by hexanoyl-lysine adduct formation. |
2008-04-15 |
2023-08-12 |
human |
| Michael E Greenberg, Xin-Min Li, Bogdan G Gugiu, Xiaodong Gu, Jun Qin, Robert G Salomon, Stanley L Haze. The lipid whisker model of the structure of oxidized cell membranes. The Journal of biological chemistry. vol 283. issue 4. 2008-03-26. PMID:18045864. |
as cellular membranes undergo lipid peroxidation, such as during senescence or apoptosis, previously hydrophobic portions of fatty acids will move from the interior of the lipid bilayer to the aqueous exterior. |
2008-03-26 |
2023-08-12 |
Not clear |
| Tomohiro Miike, Hiroaki Shirahase, Hiroshi Jino, Kazuyoshi Kunishiro, Mamoru Kanda, Kazuyoshi Kurahash. Effects of an anti-oxidative ACAT inhibitor on apoptosis/necrosis and cholesterol accumulation under oxidative stress in THP-1 cell-derived foam cells. Life sciences. vol 82. issue 1-2. 2008-03-11. PMID:18037448. |
these preventive effects of ky-455 and vc were accompanied by the inhibition of lipid peroxidation in culture medium containing acldl and cu2+, suggesting the involvement of oxidized acldl in apoptosis and necrosis. |
2008-03-11 |
2023-08-12 |
Not clear |
| Yang Liu, Hong Zhang, Luwei Zhang, Qingming Zhou, Xiaohu Wang, Jing Long, Tao Dong, Weiping Zha. Antioxidant N-acetylcysteine attenuates the acute liver injury caused by X-ray in mice. European journal of pharmacology. vol 575. issue 1-3. 2008-03-06. PMID:17825281. |
an acute study was carried out to determine alterations in lipid peroxidation (determined by measuring malondiadehyde (mda) level), glutathione (gsh) content and superoxide dismutase (sod) activity (assayed by colorimetric method), and dna damage (characterized by dna-single strand break using with comet assay) as well as cell apoptosis (measured by flow cytometry) at 12 h after irradiation. |
2008-03-06 |
2023-08-12 |
mouse |
| Yang Liu, Hong Zhang, Luwei Zhang, Qingming Zhou, Xiaohu Wang, Jing Long, Tao Dong, Weiping Zha. Antioxidant N-acetylcysteine attenuates the acute liver injury caused by X-ray in mice. European journal of pharmacology. vol 575. issue 1-3. 2008-03-06. PMID:17825281. |
in addition, significant positive correlations were observed between mda level and dna damage or cell apoptosis, implying that lipid peroxidation plays a major role in x-ray-induced liver injury. |
2008-03-06 |
2023-08-12 |
mouse |
| Ke-Xuan Liu, Wei He, Timo Rinne, Ying Liu, Ming-Qi Zhao, Wei-Kang W. The effect of ginkgo biloba extract (EGb 761) pretreatment on intestinal epithelial apoptosis induced by intestinal ischemia/reperfusion in rats: role of ceramide. The American journal of Chinese medicine. vol 35. issue 5. 2008-02-05. PMID:17963320. |
ii/r caused intestinal mucosal epithelial apoptosis and over-production of the ceramide accompanied by up-regulation of smase mrna expression and increases of lipid peroxidation. |
2008-02-05 |
2023-08-12 |
rat |
| Ke-Xuan Liu, Wei He, Timo Rinne, Ying Liu, Ming-Qi Zhao, Wei-Kang W. The effect of ginkgo biloba extract (EGb 761) pretreatment on intestinal epithelial apoptosis induced by intestinal ischemia/reperfusion in rats: role of ceramide. The American journal of Chinese medicine. vol 35. issue 5. 2008-02-05. PMID:17963320. |
egb 761 pretreatment significantly decreased apoptosis index, and concurrently reduced the ceramide generation accompanied by down-regulation of smase expression and inhibition of lipid peroxidation. |
2008-02-05 |
2023-08-12 |
rat |
| Yuh-Chiang Shen, Yea-Hwey Wang, Yueh-Ching Chou, Kuo-Tong Liou, Jiin-Cherng Yen, Wen-Yen Wang, Jyh-Fei Lia. Dimemorfan protects rats against ischemic stroke through activation of sigma-1 receptor-mediated mechanisms by decreasing glutamate accumulation. Journal of neurochemistry. vol 104. issue 2. 2008-02-05. PMID:18173806. |
dimemorfan treatment (10 microg/kg, i.v., at the time of reperfusion) inhibited the expressions of monocyte chemoattractant protein-1 and interleukin-1beta, which occurred in parallel with decreases in neutrophil infiltration, activation of inflammation-related signals (p38 mitogen-activated protein kinase, nuclear factor-kappab, and signal transducer and activator of transcription-1), expression of neuronal and inducible nitric oxide synthase, oxidative/nitrosative tissue damage (lipid peroxidation, protein nitrosylation, and 8-hydroxy-guanine formation), and apoptosis in the ipsilateral cortex after ci/r injury. |
2008-02-05 |
2023-08-12 |
rat |
| Neife Aparecida Guinaim dos Santos, Nádia Maria Martins, Carlos Curti, Maria de Lourdes Pires Bianchi, Antonio Cardozo dos Santo. Dimethylthiourea protects against mitochondrial oxidative damage induced by cisplatin in liver of rats. Chemico-biological interactions. vol 170. issue 3. 2008-02-01. PMID:17850778. |
dmtu protected against (a) decreased hepatic atp levels; (b) lipid peroxidation; (c) cardiolipin oxidation; (d) sulfhydryl protein oxidation; (e) mitochondrial membrane rigidification; (f) gsh oxidation; (g) nadph oxidation; (h) apoptosis. |
2008-02-01 |
2023-08-12 |
rat |
| J A Solís Herruzo, I García Ruiz, M Pérez Carreras, M T Muñoz Yagü. Non-alcoholic fatty liver disease. From insulin resistance to mitochondrial dysfunction. Revista espanola de enfermedades digestivas : organo oficial de la Sociedad Espanola de Patologia Digestiva. vol 98. issue 11. 2007-12-13. PMID:17198477. |
consequences of oxidative stress include: lipid peroxidation in cell membranes, stellate cell activation in the liver, liver fibrosis, chronic inflammation, and apoptosis. |
2007-12-13 |
2023-08-12 |
Not clear |
| Hiroyuki Wakabayashi, Hirofumi Miyauchi, Kouichirou Shin, Koji Yamauchi, Ichiro Matsumoto, Keiko Abe, Mitsunori Takas. Orally administered lactoperoxidase increases expression of the FK506 binding protein 5 gene in epithelial cells of the small intestine of mice: a DNA microarray study. Bioscience, biotechnology, and biochemistry. vol 71. issue 9. 2007-12-12. PMID:17827675. |
lpo administration upregulated 78 genes, including genes involved in metabolism, immunity, apoptosis, and the cell cycle, and downregulated nine genes, including immunity-related genes. |
2007-12-12 |
2023-08-12 |
mouse |
| Andreja Leskovac, Gordana Joksic, Teodora Jankovic, Katarina Savikin, Nebojsa Menkovi. Radioprotective properties of the phytochemically characterized extracts of Crataegus monogyna, Cornus mas and Gentianella austriaca on human lymphocytes in vitro. Planta medica. vol 73. issue 11. 2007-12-06. PMID:17764067. |
significant radiorecovery potentials of c. mas and c. monogyna were observed, seen as a reduced incidence of radiation-induced micronuclei (19.23% and 13.24%, respectively), reduced levels of lipid peroxidation products (50.04% and 13.18%, respectively) and two-fold enhanced apoptosis. |
2007-12-06 |
2023-08-12 |
human |
| Andreja Leskovac, Gordana Joksic, Teodora Jankovic, Katarina Savikin, Nebojsa Menkovi. Radioprotective properties of the phytochemically characterized extracts of Crataegus monogyna, Cornus mas and Gentianella austriaca on human lymphocytes in vitro. Planta medica. vol 73. issue 11. 2007-12-06. PMID:17764067. |
g. austriaca possesses strong antioxidant properties, significantly reducing lipid peroxidation and the incidence of micronuclei (for 30.88% and 35.56%, respectively) while enhancing apoptosis with no perturbation of the cell cycle. |
2007-12-06 |
2023-08-12 |
human |