| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| F Filipak Neto, S M Zanata, H C Silva de Assis, D Bussolaro, M V M Ferraro, M A F Randi, J R M Alves Costa, M M Cestari, H Roche, C A Oliveira Ribeir. Use of hepatocytes from Hoplias malabaricus to characterize the toxicity of a complex mixture of lipophilic halogenated compounds. Toxicology in vitro : an international journal published in association with BIBRA. vol 21. issue 4. 2007-08-06. PMID:17293077. |
the dmso at 0.1% increased the lipid peroxidation, gsh concentration, apoptosis and dna damage. |
2007-08-06 |
2023-08-12 |
Not clear |
| Myoungsook Lee, Myung-Ae Ba. Docosahexaenoic acid induces apoptosis in CYP2E1-containing HepG2 cells by activating the c-Jun N-terminal protein kinase related mitochondrial damage. The Journal of nutritional biochemistry. vol 18. issue 5. 2007-07-20. PMID:16963249. |
our results indicated that dha-mediated apoptosis in e47 cells was induced through the activation of the jnk-related cell death pathway, which may be involved in the production of lpo or reactive oxygen species during the cyp2e1 catalytic cycle, followed by mitochondrial injury and apoptosis. |
2007-07-20 |
2023-08-12 |
human |
| Steven T S Lim, Klaus Dragull, Chung-Shih Tang, Harry C Bittenbender, Jimmy T Efird, Pratibha V Nerurka. Effects of kava alkaloid, pipermethystine, and kavalactones on oxidative stress and cytochrome P450 in F-344 rats. Toxicological sciences : an official journal of the Society of Toxicology. vol 97. issue 1. 2007-07-03. PMID:17329236. |
treatment of f-344 rats with pm (10 mg/kg) and kre (100 mg/kg) for 2 weeks failed to elicit any significant changes in liver function tests or cause severe hepatic toxicity as measured by lipid peroxidation and apoptosis markers such as malondialdehyde, bax, and bcl-2. |
2007-07-03 |
2023-08-12 |
human |
| Angelo Cerbone, Cristina Toaldo, Stefano Laurora, Federica Briatore, Stefania Pizzimenti, Mario U Dianzani, Carlo Ferretti, Giuseppina Barrer. 4-Hydroxynonenal and PPARgamma ligands affect proliferation, differentiation, and apoptosis in colon cancer cells. Free radical biology & medicine. vol 42. issue 11. 2007-06-19. PMID:17462534. |
4-hydroxynonenal (hne), a product of lipid peroxidation, inhibits proliferation and induces differentiation or apoptosis in neoplastic cells. |
2007-06-19 |
2023-08-12 |
Not clear |
| M Li, Z M Kong, Z L Li. Antioxidant enzyme activities and lipid peroxidation induced by eicosapentaenoic acid (EPA) in PC12 cells. Cell biology and toxicology. vol 22. issue 5. 2007-06-07. PMID:16847743. |
in this study, the epa induced lipid peroxidation and response of antioxidative enzymes have been investigated in rat pheochromocytoma pc12 cells to elucidate the mechanisms of apoptosis induced by the polyunsaturated fatty acid epa. |
2007-06-07 |
2023-08-12 |
rat |
| M Li, Z M Kong, Z L Li. Antioxidant enzyme activities and lipid peroxidation induced by eicosapentaenoic acid (EPA) in PC12 cells. Cell biology and toxicology. vol 22. issue 5. 2007-06-07. PMID:16847743. |
the results suggest that in pc12 cells the mechanism of apoptosis induced by epa may be partly due to lipid peroxidation. |
2007-06-07 |
2023-08-12 |
rat |
| Manuela Gago-Dominguez, Xuejuan Jiang, J Esteban Castela. Lipid peroxidation and the protective effect of physical exercise on breast cancer. Medical hypotheses. vol 68. issue 5. 2007-06-06. PMID:17113718. |
specifically, we describe (1) the sources of free radicals occurring during exercise, (2) existing experimental data on physical exercise, lipid peroxidation and cancer, (3) existing supporting data implicating exercise-induced reactive oxygen species (ros) as the mechanism responsible for increased apoptosis in different cell systems, and (4) changes in the antioxidant enzymes glutathione s transferases (gsts), superoxide dismutase (sod), glutathione peroxidase (gpx), and catalase (cat) that occur after physical exercise, which are believed to be a physiologic response to oxidative stress induced by physical exercise. |
2007-06-06 |
2023-08-12 |
cat |
| Yoshisuke Haruna, Naoki Kashihara, Minoru Satoh, Naruya Tomita, Tamehachi Namikoshi, Tamaki Sasaki, Toshihiko Fujimori, Ping Xie, Yashpal S Kanwa. Amelioration of progressive renal injury by genetic manipulation of Klotho gene. Proceedings of the National Academy of Sciences of the United States of America. vol 104. issue 7. 2007-05-17. PMID:17287345. |
this improvement was associated with dramatic improvement in renal functions, morphological lesions, and cytochrome c oxidase activity but a reduction in beta-galactosidase activity (a senescence-associated protein), mitochondrial dna fragmentation, superoxide anion generation, lipid peroxidation, and bax protein expression and apoptosis. |
2007-05-17 |
2023-08-12 |
mouse |
| Rogéria C Mund, Nathalia Pizato, Sandro Bonatto, Everson A Nunes, Thiago Vicenzi, Ricardo Tanhoffer, Heloisa H P de Oliveira, Rui Curi, Philip C Calder, Luiz C Fernande. Decreased tumor growth in Walker 256 tumor-bearing rats chronically supplemented with fish oil involves COX-2 and PGE2 reduction associated with apoptosis and increased peroxidation. Prostaglandins, leukotrienes, and essential fatty acids. vol 76. issue 2. 2007-05-09. PMID:17234396. |
these results suggest that reduction of tumor growth by fo involves an increase in apoptosis and of lipid peroxidation in tumor tissue, with a reduction in tumor cell proliferation ex vivo, cox-2 expression and pge2 production. |
2007-05-09 |
2023-08-12 |
rat |
| Marzena Podhorska-Okolow, Piotr Dziegiel, Eugenia Murawska-Cialowicz, Jolanta Saczko, Julita Kulbacka, Agnieszka Gomulkiewicz, Katia Rossini, Zbigniew Jethon, Ugo Carraro, Maciej Zabe. Effects of adaptive exercise on apoptosis in cells of rat renal tubuli. European journal of applied physiology. vol 99. issue 3. 2007-04-20. PMID:17102979. |
we measured apoptosis, expression of at1 and at2 receptors, level of lipid peroxidation (tbars) and activities of antioxidant enzymes, sod, gpx and cat in kidneys of sedentary rats that were exposed to acute exercise and rats that were trained for 8 weeks. |
2007-04-20 |
2023-08-12 |
rat |
| Mehmet Guney, Baha Oral, Gulnur Take, Seren Gulsen Giray, Tamer Munga. Effect of fluoride intoxication on endometrial apoptosis and lipid peroxidation in rats: role of vitamins E and C. Toxicology. vol 231. issue 2-3. 2007-04-17. PMID:17227693. |
effect of fluoride intoxication on endometrial apoptosis and lipid peroxidation in rats: role of vitamins e and c. fluoride is a strong, hard anion and cumulative toxic agent. |
2007-04-17 |
2023-08-12 |
rat |
| Mehmet Guney, Baha Oral, Gulnur Take, Seren Gulsen Giray, Tamer Munga. Effect of fluoride intoxication on endometrial apoptosis and lipid peroxidation in rats: role of vitamins E and C. Toxicology. vol 231. issue 2-3. 2007-04-17. PMID:17227693. |
from these results, it can be concluded that subchronic fluoride administration causes endometrial apoptosis, and lipid peroxidation may be a molecular mechanism involved in fluoride-induced toxicity. |
2007-04-17 |
2023-08-12 |
rat |
| L B Dudnik, A N Tsiupko, M A Shupik, G G Akhaladze, E I Gal'perin, L V Platonova, E A Pantaz, V V Iasnetsov, L D Smirnov, A V Alesenk. [Relationship of tumor necrosis factor alpha expression with activation of sphingomyelinase and lipid peroxidation after removal of cholestatic factor]. Izvestiia Akademii nauk. Seriia biologicheskaia. issue 1. 2007-04-12. PMID:17352195. |
the obtained data indicate that hepatocyte apoptosis after bile outflow restoration in late cholestasis can be due to the activation of the sphingomyelin cycle, lpo, and tnfalpha expression. |
2007-04-12 |
2023-08-12 |
Not clear |
| L B Dudnik, A N Tsiupko, M A Shupik, G G Akhaladze, E I Gal'perin, L V Platonova, E A Pantaz, V V Iasnetsov, L D Smirnov, A V Alesenk. [Relationship of tumor necrosis factor alpha expression with activation of sphingomyelinase and lipid peroxidation after removal of cholestatic factor]. Izvestiia Akademii nauk. Seriia biologicheskaia. issue 1. 2007-04-12. PMID:17352195. |
the synergistic interaction can sharply increase the proapoptotic capacity of each of these factors since tnfalpha activates smase and lpo, smase activity depends on the lpo rate, while ceramide, an smase-produced secondary messenger of apoptosis, can induce oxidative stress. |
2007-04-12 |
2023-08-12 |
Not clear |
| Mehboob Ali, Shakilur Rahman, Hasibur Rehman, Kanchan Bhatia, Rizwan A Ansari, Sheikh Raisuddi. Pro-apoptotic effect of fly ash leachates in hepatocytes of freshwater fish (Channa punctata Bloch). Toxicology in vitro : an international journal published in association with BIBRA. vol 21. issue 1. 2007-04-09. PMID:17052884. |
lactate dehydrogenase, lpo and apoptosis as biomarkers of cytotoxicity have recently been used for assessment of ecotoxicological impact of environmental chemicals. |
2007-04-09 |
2023-08-12 |
Not clear |
| Mohammed Abul Kashem, Gabriel James, Clive Harper, Peter Wilce, Izuru Matsumot. Differential protein expression in the corpus callosum (splenium) of human alcoholics: a proteomics study. Neurochemistry international. vol 50. issue 2. 2007-03-30. PMID:17141922. |
our data also indicate the importance of other pathways including oxidative stress, lipid peroxidation and apoptosis as potential causes of alcohol-induced brain damage. |
2007-03-30 |
2023-08-12 |
human |
| Adriana Marquez, Saul Villa-Treviño, Françoise Guérau. The LEC rat: a useful model for studying liver carcinogenesis related to oxidative stress and inflammation. Redox report : communications in free radical research. vol 12. issue 1. 2007-03-23. PMID:17263906. |
lipid peroxidation products, such as malondialdehyde (mda) and 4-hydroxy-2-nonenal (hne), are closely related to carcinogenesis as they are potent mutagens and they have been suggested as modulators of signal pathways related to proliferation and apoptosis, two processes implicated in cancer development. |
2007-03-23 |
2023-08-12 |
human |
| Orhan Sen, Hakan Caner, M Volkan Aydin, Ozlem Ozen, Basar Atalay, Nur Altinors, Murad Bavbe. The effect of mexiletine on the level of lipid peroxidation and apoptosis of endothelium following experimental subarachnoid hemorrhage. Neurological research. vol 28. issue 8. 2007-03-21. PMID:17288746. |
the effect of mexiletine on the level of lipid peroxidation and apoptosis of endothelium following experimental subarachnoid hemorrhage. |
2007-03-21 |
2023-08-12 |
Not clear |
| Juliann G Kiang, K T Tse. Biology of hypoxia. The Chinese journal of physiology. vol 49. issue 5. 2007-03-20. PMID:17294830. |
hypoxia also increases intracellular ca2+ concentration, tumor necrosis factor-alpha, lipid peroxidation, prostaglandin e2 production, activity of caspase-3 and -9, and release of cytochrome c from mitochondria, apoptosis inducible factor, and endonuclease g. however, it has been shown that downregulation of inos can limit cell injury caused by hypoxia. |
2007-03-20 |
2023-08-12 |
Not clear |
| Vishal Chanana, Siddharth Majumdar, Praveen Rish. Involvement of caspase-3, lipid peroxidation and TNF-alpha in causing apoptosis of macrophages by coordinately expressed Salmonella phenotype under stress conditions. Molecular immunology. vol 44. issue 7. 2007-03-13. PMID:17027970. |
involvement of caspase-3, lipid peroxidation and tnf-alpha in causing apoptosis of macrophages by coordinately expressed salmonella phenotype under stress conditions. |
2007-03-13 |
2023-08-12 |
Not clear |