| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| James D West, Chuan Ji, Stephen T Duncan, Venkataraman Amarnath, Claus Schneider, Carmelo J Rizzo, Alan R Brash, Lawrence J Marnet. Induction of apoptosis in colorectal carcinoma cells treated with 4-hydroxy-2-nonenal and structurally related aldehydic products of lipid peroxidation. Chemical research in toxicology. vol 17. issue 4. 2004-11-09. PMID:15089087. |
induction of apoptosis in colorectal carcinoma cells treated with 4-hydroxy-2-nonenal and structurally related aldehydic products of lipid peroxidation. |
2004-11-09 |
2023-08-12 |
human |
| Margie Castillo-Meléndez, Jo Ann Chow, David W Walke. Lipid peroxidation, caspase-3 immunoreactivity, and pyknosis in late-gestation fetal sheep brain after umbilical cord occlusion. Pediatric research. vol 55. issue 5. 2004-11-08. PMID:14764919. |
we have determined the effects of two 10-min uco on the distribution of the lipid peroxidation marker 4-hydroxynonenal (4-hne) and the activated form of the apoptosis marker caspase-3 in the brains of late-gestation fetal sheep. |
2004-11-08 |
2023-08-12 |
Not clear |
| Margie Castillo-Meléndez, Jo Ann Chow, David W Walke. Lipid peroxidation, caspase-3 immunoreactivity, and pyknosis in late-gestation fetal sheep brain after umbilical cord occlusion. Pediatric research. vol 55. issue 5. 2004-11-08. PMID:14764919. |
these data indicate that brief asphyxia induces widespread lipid peroxidation involving all cell types of the fetal brain and apoptosis in both neurons and glia. |
2004-11-08 |
2023-08-12 |
Not clear |
| N Philips, D Burchill, D O'Donoghue, T Keller, S Gonzale. Identification of benzene metabolites in dermal fibroblasts as nonphenolic: regulation of cell viability, apoptosis, lipid peroxidation and expression of matrix metalloproteinase 1 and elastin by benzene metabolites. Skin pharmacology and physiology. vol 17. issue 3. 2004-10-19. PMID:15087594. |
identification of benzene metabolites in dermal fibroblasts as nonphenolic: regulation of cell viability, apoptosis, lipid peroxidation and expression of matrix metalloproteinase 1 and elastin by benzene metabolites. |
2004-10-19 |
2023-08-12 |
Not clear |
| N Philips, D Burchill, D O'Donoghue, T Keller, S Gonzale. Identification of benzene metabolites in dermal fibroblasts as nonphenolic: regulation of cell viability, apoptosis, lipid peroxidation and expression of matrix metalloproteinase 1 and elastin by benzene metabolites. Skin pharmacology and physiology. vol 17. issue 3. 2004-10-19. PMID:15087594. |
these metabolites were not toxic to the cells with regard to cell viability, apoptosis and lipid peroxidation, unlike the phenolic benzene metabolites (hydroquinone, t-butyl hydroquinone and phenol) or hydrogen peroxide. |
2004-10-19 |
2023-08-12 |
Not clear |
| Tsuyoshi Tsuzuki, Yoshiko Tokuyama, Miki Igarashi, Teruo Miyazaw. Tumor growth suppression by alpha-eleostearic acid, a linolenic acid isomer with a conjugated triene system, via lipid peroxidation. Carcinogenesis. vol 25. issue 8. 2004-09-10. PMID:14963014. |
dna fragmentation was enhanced and lipid peroxidation was increased in tumor tissues of the alpha-esa-fed mice, which suggested that alpha-esa induced apoptosis via lipid peroxidation. |
2004-09-10 |
2023-08-12 |
mouse |
| Tsuyoshi Tsuzuki, Yoshiko Tokuyama, Miki Igarashi, Teruo Miyazaw. Tumor growth suppression by alpha-eleostearic acid, a linolenic acid isomer with a conjugated triene system, via lipid peroxidation. Carcinogenesis. vol 25. issue 8. 2004-09-10. PMID:14963014. |
addition of alpha-tocopherol, an antioxidant, suppressed oxidative stress and apoptosis, suggesting that these effects were associated with lipid peroxidation. |
2004-09-10 |
2023-08-12 |
mouse |
| Ji-Young Lee, Jae-Won Kim, Su-Dong Cho, Yong-Hoon Kim, Kang-Ju Choi, Woo-Hong Joo, Yong-Kweon Cho, Ja-Young Moo. Protective effect of ginseng extract against apoptotic cell death induced by 2,2',5,5'-tetrachlorobiphenyl in neuronal SK-N-MC cells. Life sciences. vol 75. issue 13. 2004-08-25. PMID:15261766. |
the addition of 500 microg/ml of ginseng extract to a culture medium significantly protected neuronal cell from the apoptosis mediated by pcb 52 and remarkably attenuated lipid peroxidation, the generation of reactive oxygen species, and dna fragmentation, and markedly reduced the pcb 52 induced proteolytic cleavage of beta-catenin and parp. |
2004-08-25 |
2023-08-12 |
human |
| Jun Xie, Qing Gu. AATF protects neural cells against oxidative damage induced by amyloid beta-peptide. Neurobiology of disease. vol 16. issue 1. 2004-08-18. PMID:15207272. |
overexpression of aatf suppressed superoxide production, inhibited peroxynitrite formation and membrane lipid peroxidation, and protected against abeta-induced apoptosis in pc12 cells. |
2004-08-18 |
2023-08-12 |
Not clear |
| Ho Jin Heo, Dae-Ok Kim, Soo Jung Choi, Dong Hoon Shin, Chang Yong Le. Potent Inhibitory effect of flavonoids in Scutellaria baicalensis on amyloid beta protein-induced neurotoxicity. Journal of agricultural and food chemistry. vol 52. issue 13. 2004-08-03. PMID:15212458. |
because amyloid beta (abeta) protein is known to increase free radical production and lipid peroxidation in pc12 nerve cells, leading to apoptosis and cell death, treatment with baicalein and baicalin may result in the prevention of cellular damage by the abeta-induced reactive oxygen species. |
2004-08-03 |
2023-08-12 |
Not clear |
| Jiawei Chen, Dayuan Li, Xingjian Zhang, Jawahar L Meht. Tumor necrosis factor-alpha-induced apoptosis of human coronary artery endothelial cells: modulation by the peroxisome proliferator-activated receptor-gamma ligand pioglitazone. Journal of cardiovascular pharmacology and therapeutics. vol 9. issue 1. 2004-07-20. PMID:15094967. |
pretreatment of cells with the ppar-gamma ligand pioglitazone blocked tnf-alpha-mediated apoptosis, caspase-3 activation, expression of bcl-2, and lipid peroxidation (p <.01 vs tnf-alpha alone). |
2004-07-20 |
2023-08-12 |
human |
| Jiawei Chen, Dayuan Li, Xingjian Zhang, Jawahar L Meht. Tumor necrosis factor-alpha-induced apoptosis of human coronary artery endothelial cells: modulation by the peroxisome proliferator-activated receptor-gamma ligand pioglitazone. Journal of cardiovascular pharmacology and therapeutics. vol 9. issue 1. 2004-07-20. PMID:15094967. |
the ppar-gamma ligand pioglitazone modulates lipid peroxidation, alters bcl-2 expression and caspase-3 activation, and finally reduces apoptosis. |
2004-07-20 |
2023-08-12 |
human |
| Musa Dirlik, Mehmet Caglikulekci, Ismail Cinel, Leyla Cinel, Lülüfer Tamer, Cengiz Pata, Arzu Kanik, Koray Ocal, Zekai Ogetman, Süha Aydi. The effect of PARS inhibition on ileal histopathology, apoptosis and lipid peroxidation in LPS-induced obstructive jaundice. Pharmacological research. vol 48. issue 2. 2004-06-24. PMID:12798666. |
the effect of pars inhibition on ileal histopathology, apoptosis and lipid peroxidation in lps-induced obstructive jaundice. |
2004-06-24 |
2023-08-12 |
rat |
| Alessandra Castegna, Christopher M Lauderback, Hafiz Mohmmad-Abdul, D Allan Butterfiel. Modulation of phospholipid asymmetry in synaptosomal membranes by the lipid peroxidation products, 4-hydroxynonenal and acrolein: implications for Alzheimer's disease. Brain research. vol 1004. issue 1-2. 2004-06-24. PMID:15033435. |
two highly reactive products of lipid peroxidation, 4-hydroxynonenal (hne) and acrolein, both elevated in alzheimer's disease (ad) brain, have been shown to induce apoptosis and disrupt cellular ion homeostasis. |
2004-06-24 |
2023-08-12 |
Not clear |
| Tsuyoshi Tsuzuki, Miki Igarashi, Teruo Miyazaw. Conjugated eicosapentaenoic acid (EPA) inhibits transplanted tumor growth via membrane lipid peroxidation in nude mice. The Journal of nutrition. vol 134. issue 5. 2004-06-10. PMID:15113964. |
therefore, we verified that cepa has a stronger in vivo antitumor effect than epa and cla, and that cepa acts through induction of apoptosis via lipid peroxidation. |
2004-06-10 |
2023-08-12 |
mouse |
| Jaimar Rincon, Maritza Romero, Ninoska Viera, Adriana Pedreañez, Jesus Mosquer. Increased oxidative stress and apoptosis in acute puromycin aminonucleoside nephrosis. International journal of experimental pathology. vol 85. issue 1. 2004-06-08. PMID:15113391. |
increased renal apoptosis, p53, bax, bcl-2 accompanied by increased o(2) (-) and no generation, lipid peroxidation (mda) and monocyte/macrophage infiltration were found in nephrotic animals. |
2004-06-08 |
2023-08-12 |
rat |
| S Santosh Kumar, Bhavani Shankar, Krishna B Saini. Effect of chlorophyllin against oxidative stress in splenic lymphocytes in vitro and in vivo. Biochimica et biophysica acta. vol 1672. issue 2. 2004-06-07. PMID:15110092. |
chl offered protection against whole body irradiation (wbi)-induced lipid peroxidation and apoptosis in lymphocytes at all the time points studied. |
2004-06-07 |
2023-08-12 |
mouse |
| Yusong Yang, Rajendra Sharma, Abha Sharma, Sanjay Awasthi, Yogesh C Awasth. Lipid peroxidation and cell cycle signaling: 4-hydroxynonenal, a key molecule in stress mediated signaling. Acta biochimica Polonica. vol 50. issue 2. 2004-06-01. PMID:12833161. |
evidence demonstrating the modulation of uv, oxidative stress, and chemical stress mediated apoptosis by blocking lipid peroxidation by the alpha-class glutathione s-transferases (gsts) is presented which suggest an important role of these enzymes in protection against oxidative stress and a role of lipid peroxidation products in stress mediated signaling. |
2004-06-01 |
2023-08-12 |
Not clear |
| Rajendra Sharma, David Brown, Sanjay Awasthi, Yusong Yang, Abha Sharma, Brad Patrick, Manjit K Saini, Sharda P Singh, Piotr Zimniak, Shivendra V Singh, Yogesh C Awasth. Transfection with 4-hydroxynonenal-metabolizing glutathione S-transferase isozymes leads to phenotypic transformation and immortalization of adherent cells. European journal of biochemistry. vol 271. issue 9. 2004-05-27. PMID:15096208. |
4-hydroxy-2-trans-nonenal (4-hne), one of the major end products of lipid peroxidation, has been shown to induce apoptosis in a variety of cell lines. |
2004-05-27 |
2023-08-12 |
mouse |
| Kiranjit K Sohi, Nidhi Mittal, Manjinder K Hundal, Krishan L Khanduj. Gallic acid, an antioxidant, exhibits antiapoptotic potential in normal human lymphocytes: A Bcl-2 independent mechanism. Journal of nutritional science and vitaminology. vol 49. issue 4. 2004-05-20. PMID:14598907. |
pretreatment of lymphocytes with gallic acid for 18 h could effectively inhibit lipid peroxidation and apoptosis induced by oxidative stress. |
2004-05-20 |
2023-08-12 |
human |