| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Irfan Rahma. The role of oxidative stress in the pathogenesis of COPD: implications for therapy. Treatments in respiratory medicine. vol 4. issue 3. 2005-10-06. PMID:15987234. |
these include oxidative inactivation of antiproteases and surfactants, mucus hypersecretion, membrane lipid peroxidation, mitochondrial respiration, alveolar epithelial injury, remodeling of extracellular matrix, and apoptosis. |
2005-10-06 |
2023-08-12 |
Not clear |
| Judy B de Haan, Nada Stefanovic, David Nikolic-Paterson, Lyndee L Scurr, Kevin D Croft, Trevor A Mori, Paul Hertzog, Ismail Kola, Robert C Atkins, Gregory H Tesc. Kidney expression of glutathione peroxidase-1 is not protective against streptozotocin-induced diabetic nephropathy. American journal of physiology. Renal physiology. vol 289. issue 3. 2005-09-27. PMID:15827346. |
at 4 mo, diabetic gpx1+/+ and -/- mice had equivalent levels of oxidative renal injury (increased kidney reactive oxygen species, kidney lipid peroxidation, urine isoprostanes, kidney deposition of advanced glycoxidation, and nitrosylation end products) and a similar degree of glomerular damage (hypertrophy, hypercellularity, sclerosis), tubular injury (apoptosis and vimentin expression), and renal fibrosis (myofibroblasts, collagen, tgf-beta excretion). |
2005-09-27 |
2023-08-12 |
mouse |
| Brian Sweeney, Prem Puri, Denis J Ree. Modulation of immune cell function by polyunsaturated fatty acids. Pediatric surgery international. vol 21. issue 5. 2005-09-08. PMID:15834730. |
they are susceptible to lipid peroxidation, and there is evidence that the products of this process may result in cell death by apoptosis, a nonphlogistic homeostatic process of cell deletion. |
2005-09-08 |
2023-08-12 |
Not clear |
| Linda Wang, Jianmin Chen, Lilian U Thompso. The inhibitory effect of flaxseed on the growth and metastasis of estrogen receptor negative human breast cancer xenograftsis attributed to both its lignan and oil components. International journal of cancer. vol 116. issue 5. 2005-09-01. PMID:15849746. |
compared to the bd group, the tumor growth rate was significantly lower (p < 0.05) in the fs, fo, and sdg + fo groups, in concordance with decreased cell proliferation and increased apoptosis; however, these did not significantly relate to the lipid peroxidation, indexed as malonaldehyde (mda), in the primary tumors. |
2005-09-01 |
2023-08-12 |
mouse |
| Margie Castillo-Meléndez, Edwin Yan, David W Walke. Expression of erythropoietin and its receptor in the brain of late-gestation fetal sheep, and responses to asphyxia caused by umbilical cord occlusion. Developmental neuroscience. vol 27. issue 2-4. 2005-08-25. PMID:16046857. |
in late-gestation fetal sheep, asphyxia produced by umbilical cord occlusion (uco) results in widespread lipid peroxidation and apoptosis. |
2005-08-25 |
2023-08-12 |
Not clear |
| N Serbecic, A K Ehmann, S C Beutelspache. [Reduction of lipid peroxidation and apoptosis in corneal endothelial cells by vitamin A]. Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft. vol 102. issue 6. 2005-08-23. PMID:15549323. |
[reduction of lipid peroxidation and apoptosis in corneal endothelial cells by vitamin a]. |
2005-08-23 |
2023-08-12 |
Not clear |
| Samarjit Das, Hajime Otani, Nilanjana Maulik, Dipak K Da. Lycopene, tomatoes, and coronary heart disease. Free radical research. vol 39. issue 4. 2005-08-11. PMID:16032783. |
both tomato juice and lycopene reduced the extent of lipid peroxidation; but only tomato juice, but not lycopene, improved post-ischemic ventricular function, and reduced myocardial infarct size and cardiomyocyte apoptosis. |
2005-08-11 |
2023-08-12 |
rat |
| Jagadeesan Nair, Susanne Strand, Norbert Frank, Jutta Knauft, Horst Wesch, Peter R Galle, Helmut Bartsc. Apoptosis and age-dependant induction of nuclear and mitochondrial etheno-DNA adducts in Long-Evans Cinnamon (LEC) rats: enhanced DNA damage by dietary curcumin upon copper accumulation. Carcinogenesis. vol 26. issue 7. 2005-07-29. PMID:15790590. |
lipid peroxidation (lpo)-induced etheno-dna adducts in nuclear- and mitochondrial-dna along with apoptosis was measured in lec rat liver. |
2005-07-29 |
2023-08-12 |
human |
| Eun Sun Yang, Joon-Hyuck Yang, Ji Eun Park, Jeen-Woo Par. Oxalomalate, a competitive inhibitor of NADP+ -dependent isocitrate dehydrogenase, regulates lipid peroxidation-mediated apoptosis in U937 cells. Free radical research. vol 39. issue 1. 2005-07-25. PMID:15875816. |
upon exposure to 2,2'-azobis (2-amidinopropane) hydrochloride (aaph) to u937 cells, which induces lipid peroxidation in membranes, the susceptibility to apoptosis was higher in oxalomalate-treated cells as compared to control cells. |
2005-07-25 |
2023-08-12 |
Not clear |
| Joe M McCord, Marvin A Edea. SOD, oxidative stress and human pathologies: a brief history and a future vision. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 59. issue 4. 2005-07-20. PMID:15862706. |
when flagrantly overproduced, however, the radical can initiate lipid peroxidation, protein oxidation, and dna damage, leading to cell dysfunction and death by apoptosis or necrosis. |
2005-07-20 |
2023-08-12 |
human |
| Ye Sun, Ying Mu, Shumei Ma, Pingsheng Gong, Ganglin Yan, Jiuqiu Liu, Jiacong Shen, Guimin Lu. The molecular mechanism of protecting cells against oxidative stress by 2-selenium-bridged beta-cyclodextrin with glutathione peroxidase activity. Biochimica et biophysica acta. vol 1743. issue 3. 2005-06-09. PMID:15843033. |
ultraviolet b (uvb) induces apoptosis and lipid peroxidation of nih3t3 cells by producing reactive oxygen species (ros). |
2005-06-09 |
2023-08-12 |
Not clear |
| James D West, Chuan Ji, Lawrence J Marnet. Modulation of DNA fragmentation factor 40 nuclease activity by poly(ADP-ribose) polymerase-1. The Journal of biological chemistry. vol 280. issue 15. 2005-06-07. PMID:15703174. |
parp-1 poly(adp-ribosyl)ation correlated directly with induction of apoptosis by the lipid peroxidation product, 4-hydroxy-2-nonenal. |
2005-06-07 |
2023-08-12 |
Not clear |
| M Volkan Aydin, Hakan Caner, Orhan Sen, Ozlem Ozen, Basar Atalay, Melih Cekinmez, Nur Altinor. Effect of melatonin on cerebral vasospasm following experimental subarachnoid hemorrhage. Neurological research. vol 27. issue 1. 2005-05-27. PMID:15829164. |
the current study was undertaken to determine whether melatonin therapy reverses vasospasm and prevents apoptosis by inhibiting lipid peroxidation in an experimental subarachnoid hemorrhage (sah) model. |
2005-05-27 |
2023-08-12 |
Not clear |
| Elzbieta Bonda, Tadeusz Włostowski, Alicja Krasowsk. Testicular toxicity induced by dietary cadmium is associated with decreased testicular zinc and increased hepatic and renal metallothionein and zinc in the bank vole (Clethrionomys glareolus). Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine. vol 17. issue 6. 2005-05-19. PMID:15689104. |
the cd-induced histopathological changes and apoptosis were accompanied by increased testicular lipid peroxidation, decreased testicular zn concentration and elevated levels of hepatic and renal mt and zn. |
2005-05-19 |
2023-08-12 |
Not clear |
| Aysun Ozkan, Kayahan Fişki. Epirubicin HCl toxicity in human-liver derived hepatoma G2 cells. Polish journal of pharmacology. vol 56. issue 4. 2005-05-13. PMID:15520498. |
it is proposed that production of reactive oxygen species increased by the treatment with epirubicin hcl can cause lipid peroxidation, which subsequently promotes apoptosis and reduces cell viability. |
2005-05-13 |
2023-08-12 |
Not clear |
| Kodipura Doreswamy, Balakrishna Shrilatha, Thimappa Rajeshkumar, Muralidhar. Nickel-induced oxidative stress in testis of mice: evidence of DNA damage and genotoxic effects. Journal of andrology. vol 25. issue 6. 2005-05-02. PMID:15477375. |
subsequently, multiple sublethal doses (1.25, 2.5, and 5.0 micromol/100 g of body weight per day for 3 days) were used to characterize effects on testicular histoarchitecture, lipid peroxidation (lpo) in testis (homogenates, microsomal or mitochondrial fractions) and epididymal sperm, dna damage, induction of apoptosis in testis, and incidence of sperm head abnormalities. |
2005-05-02 |
2023-08-12 |
mouse |
| Ji-Seon Lee, Jong-Sun Chang, Ji Youl Lee, Jung-Ae Ki. Capsaicin-induced apoptosis and reduced release of reactive oxygen species in MBT-2 murine bladder tumor cells. Archives of pharmacal research. vol 27. issue 11. 2005-03-30. PMID:15595419. |
furthermore, capsaicin at the concentration of inducing apoptosis also markedly reduced the level of reactive oxygen species and lipid peroxidation, implying that capsaicin may enhance the antitumor effect of bcg in bladder cancer treatment. |
2005-03-30 |
2023-08-12 |
Not clear |
| Saul R Powell, Lin L Mantell, Valerie Garramone, Steven Drexler, Saul Teichber. Acute effects of nonlethal in utero hypoxia on fetal guinea pig heart and lack of persistent cardiac or cerebral effects in the neonate. Biology of the neonate. vol 86. issue 4. 2005-03-17. PMID:15273443. |
guinea pigs (50-55 days gestation) were exposed to 7% o2 for 2 h and room air for 4 h. fetal hearts were harvested before hypoxia, at the end of hypoxia, and 4 h after hypoxia, and analyzed for: apoptosis (tunel), histology, lipid peroxidation and atp. |
2005-03-17 |
2023-08-12 |
Not clear |
| James P Fabisiak, Grigory G Borisenko, Valerian E Kaga. Quantitative method of measuring phosphatidylserine externalization during apoptosis using electron paramagnetic resonance spectroscopy and annexin-conjugated iron. Methods in molecular biology (Clifton, N.J.). vol 291. 2005-02-22. PMID:15502242. |
the application of this technique, alone and in concert with the ps oxidation method presented in the previous chapter, will greatly aid in studying the mechanistic connection between lipid peroxidation and translocation events during apoptosis. |
2005-02-22 |
2023-08-12 |
Not clear |
| Behzat Cimen, Nurten Türközkan, Ilgim Seven, Ali Unlü, Cimen Karas. Impaired Na+,K+-ATPase activity as a mechanism of reactive nitrogen species-induced cytotoxicity in guinea pig liver exposed to lipopolysaccharides. Molecular and cellular biochemistry. vol 259. issue 1-2. 2005-01-25. PMID:15124907. |
in animal models of endotoxin, the excess production of no and the reactive nitrogen species (rns), are potent oxidant and nitrating agents, lead to lipid peroxidation, apoptosis, tissue dysfunction and injury and inactivate enzymes in many cell types. |
2005-01-25 |
2023-08-12 |
Not clear |