| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ping-Yuan Lin, Hung-Jen Liu, Ching-Dong Chang, Chi-I Chang, Jue-Liang Hsu, Ming-Huei Liao, Jeng-Woei Lee, Wen-Ling Shi. Avian reovirus S1133-induced DNA damage signaling and subsequent apoptosis in cultured cells and in chickens. Archives of virology. vol 156. issue 11. 2011-12-29. PMID:21779911. |
ros and lipid peroxidation levels were increased, and arv s1133 and σc caused apoptosis mediated by dna damage signaling. |
2011-12-29 |
2023-08-12 |
Not clear |
| Erkan Yurtcu, Ozlem Darcansoy Iseri, Feride I Sahi. Effects of ascorbic acid and β-carotene on HepG2 human hepatocellular carcinoma cell line. Molecular biology reports. vol 38. issue 7. 2011-12-27. PMID:21116852. |
ascorbic acid and β-carotene were applied to cells as plasma peak concentrations (70 and 8 μm, respectively) and their half concentrations (35 and 4 μm, respectively) for 24 and 48 h. genotoxic and cytotoxic effects of ascorbic acid and β-carotene were evaluated by alkali single cell gel electrophoresis (scge), acridine orange/ethidium bromide staining patterns of cells (apoptosis and necrosis) and lipid peroxidation (thiobarbituric acid reactive substances, tbars). |
2011-12-27 |
2023-08-12 |
human |
| Stefania Zampieri, Synthia H Mellon, Terry D Butters, Marco Nevyjel, Douglas F Covey, Bruno Bembi, Andrea Dardi. Oxidative stress in NPC1 deficient cells: protective effect of allopregnanolone. Journal of cellular and molecular medicine. vol 13. issue 9B. 2011-12-23. PMID:18774957. |
allo treatment of fibroblasts from npc patients or npc1 knockdown cells reduced the levels of ros and lipid peroxidation and prevented peroxide-induced apoptosis and nf-kb activation. |
2011-12-23 |
2023-08-12 |
mouse |
| El-Sayed M El-Sayed, Abdel-Aziz H Abdel-Aziz, Samira Saleh, Ahmed S Saa. The chemopreventive effect of dimethylthiourea against carmustine-induced myelotoxicity in rats. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 49. issue 9. 2011-12-07. PMID:21620922. |
the possible chemopreventive role of dimethylthiourea (dmtu) against carmustine (1,3-bis(2-chloroethyl)-1-nitrosourea, bcnu)-induced myelotoxicity was assessed through evaluation of apoptosis, lipid peroxidation, glutathione (gsh) content and some antioxidant enzymes activities in bone marrow cells of rats. |
2011-12-07 |
2023-08-12 |
rat |
| Nurdan Bedirli, Nalan Akyürek, Omer Kurtipek, Mustafa Kavutcu, Seyfi Kartal, Asli Cavunt Bayrakta. Thoracic epidural bupivacaine attenuates inflammatory response, intestinal lipid peroxidation, oxidative injury, and mucosal apoptosis induced by mesenteric ischemia/reperfusion. Anesthesia and analgesia. vol 113. issue 5. 2011-12-07. PMID:21865496. |
thoracic epidural bupivacaine attenuates inflammatory response, intestinal lipid peroxidation, oxidative injury, and mucosal apoptosis induced by mesenteric ischemia/reperfusion. |
2011-12-07 |
2023-08-12 |
rat |
| Lijuan Wang, Yingxian Sun, Michio Asahi, Kinya Ots. Acrolein, an environmental toxin, induces cardiomyocyte apoptosis via elevated intracellular calcium and free radicals. Cell biochemistry and biophysics. vol 61. issue 1. 2011-11-29. PMID:21350837. |
acrolein, an unsaturated aldehyde, is an environmental toxin known to inhibit mitochondrial electron transport chain in brain and induce lipid peroxidation and apoptosis. |
2011-11-29 |
2023-08-12 |
mouse |
| Wei-Wei Xing, Min-Ji Zou, Shen Liu, Tao Xu, Jia-Xi Wang, Dong-Gang X. Interleukin-22 protects against acute alcohol-induced hepatotoxicity in mice. Bioscience, biotechnology, and biochemistry. vol 75. issue 7. 2011-11-28. PMID:21737938. |
the results indicated that acute alcohol administration caused prominent hepatic microvesicular steatosis and an elevation of serum transaminase activities, induced a significant decrease in hepatic glutathione in conjunction with enhanced lipid peroxidation, and increased hepatocyte apoptosis as well as hepatic tnf-alpha production. |
2011-11-28 |
2023-08-12 |
mouse |
| Shiekh Tanveer Ahmad, Wani Arjumand, Amlesh Seth, Sana Nafees, Summya Rashid, Nemat Ali, Sarwat Sultan. Preclinical renal cancer chemopreventive efficacy of geraniol by modulation of multiple molecular pathways. Toxicology. vol 290. issue 1. 2011-11-21. PMID:21907755. |
the chemopreventive efficacy of goh was studied in terms of xenobiotic metabolizing enzyme activities, lpo, redox status, serum toxicity markers and the expression of putative nephrotoxicity biomarker kim-1, tumor suppressor gene p53, inflammation, cell proliferation and apoptosis related genes in the kidney tissue. |
2011-11-21 |
2023-08-12 |
rat |
| Paola Barraja, Patrizia Diana, Alessandra Montalbano, Anna Carbone, Giampietro Viola, Giuseppe Basso, Alessia Salvador, Daniela Vedaldi, Francesco Dall'Acqua, Girolamo Cirrincion. Pyrrolo[3,4-h]quinolinones a new class of photochemotherapeutic agents. Bioorganic & medicinal chemistry. vol 19. issue 7. 2011-10-24. PMID:21397509. |
the induced cellular photocytotoxicity was related to apoptosis with the involvement of mitochondria and lysosomes, alteration of cell cycle profile and membrane lipid peroxidation. |
2011-10-24 |
2023-08-12 |
Not clear |
| Akshay Pratap, Ravikiran Panakanti, Ningning Yang, Ramasubramanian Lakshmi, Kian A Modanlou, James D Eason, Ram I Mahat. Cyclopamine attenuates acute warm ischemia reperfusion injury in cholestatic rat liver: hope for marginal livers. Molecular pharmaceutics. vol 8. issue 3. 2011-09-23. PMID:21491930. |
expression of hh ligands (sonic hedgehog, patched-1 and glioblastoma-1), assessment of liver injury, neutrophil infiltration, cytokines, lipid peroxidation, cell proliferation and apoptosis were determined. |
2011-09-23 |
2023-08-12 |
rat |
| Yudong Jia, Jinxing Lin, Yuling Mi, Caiqiao Zhan. Quercetin attenuates cadmium-induced oxidative damage and apoptosis in granulosa cells from chicken ovarian follicles. Reproductive toxicology (Elmsford, N.Y.). vol 31. issue 4. 2011-09-20. PMID:21262342. |
however, simultaneous supplementation with 1 μg/ml quercetin protected granulosa cells against cadmium-induced cytotoxicity through attenuating lipid peroxidation, renewing antioxidant enzymes activities and alleviating apoptosis by modulating xiap, bax and bcl2 expression, and inhibiting caspase-3 activity. |
2011-09-20 |
2023-08-12 |
chicken |
| Yudong Jia, Jinxing Lin, Yuling Mi, Caiqiao Zhan. Quercetin attenuates cadmium-induced oxidative damage and apoptosis in granulosa cells from chicken ovarian follicles. Reproductive toxicology (Elmsford, N.Y.). vol 31. issue 4. 2011-09-20. PMID:21262342. |
therefore, these results suggested that quercetin, as a widely distributed dietary antioxidant, contributes potentially to prevent cadmium-induced cytotoxicity in granulosa cells through attenuating lipid peroxidation, elevating intracellular antioxidant status and inhibiting apoptosis to ensure reproductive health. |
2011-09-20 |
2023-08-12 |
chicken |
| Eduardo E Montalvo-Javé, José A Ortega-Salgado, Andrés Castell, Daniel Carrasco-Daza, David Jay, Roberto Gleason, Eduardo Muñoz, César Montalvo-Arenas, Rolando Hernández-Muñoz, Enrique Piñ. Piroxicam and meloxicam ameliorate hepatic oxidative stress and protein carbonylation in Kupffer and sinusoidal endothelial cells promoted by ischemia-reperfusion injury. Transplant international : official journal of the European Society for Organ Transplantation. vol 24. issue 5. 2011-08-01. PMID:21261753. |
in liver samples, we studied cellular alterations by means of histologic studies, lipid peroxidation, pc by immunohistochemistry, apoptosis and reactive oxygen species in bile by electron paramagnetic resonance. |
2011-08-01 |
2023-08-12 |
rat |
| A Rus, M A Peinado, S Blanco, M L Del Mora. Is endothelial-nitric-oxide-synthase-derived nitric oxide involved in cardiac hypoxia/reoxygenation-related damage? Journal of biosciences. vol 36. issue 1. 2011-07-26. PMID:21451249. |
lipid peroxidation, apoptosis and protein nitration, as well as no production (nox), were analysed. |
2011-07-26 |
2023-08-12 |
rat |
| Mariappan Premanathan, Krishnamoorthy Karthikeyan, Kadarkaraithangam Jeyasubramanian, Govindasamy Manivanna. Selective toxicity of ZnO nanoparticles toward Gram-positive bacteria and cancer cells by apoptosis through lipid peroxidation. Nanomedicine : nanotechnology, biology, and medicine. vol 7. issue 2. 2011-07-22. PMID:21034861. |
selective toxicity of zno nanoparticles toward gram-positive bacteria and cancer cells by apoptosis through lipid peroxidation. |
2011-07-22 |
2023-08-12 |
human |
| Wei Cui, Stephen L Chen, Ke-Qin H. Quantification and mechanisms of oleic acid-induced steatosis in HepG2 cells. American journal of translational research. vol 2. issue 1. 2011-07-14. PMID:20182586. |
oa-induced steatosis was also associated with increased lipid peroxidation, apoptosis, but decreased proliferation in these cells. |
2011-07-14 |
2023-08-12 |
Not clear |
| Wei Cui, Stephen L Chen, Ke-Qin H. Quantification and mechanisms of oleic acid-induced steatosis in HepG2 cells. American journal of translational research. vol 2. issue 1. 2011-07-14. PMID:20182586. |
the increased lipid peroxidation was related to decreased sod-1, a free radical scavenger enzyme; while increased apoptosis was related to increased active caspase-9. |
2011-07-14 |
2023-08-12 |
Not clear |
| Shinji Itoh, Akinobu Taketomi, Norifumi Harimoto, Eiji Tsujita, Tatsuya Rikimaru, Ken Shirabe, Mitsuo Shimada, Yoshihiko Maehar. Antineoplastic effects of gamma linolenic Acid on hepatocellular carcinoma cell lines. Journal of clinical biochemistry and nutrition. vol 47. issue 1. 2011-07-14. PMID:20664735. |
cell proliferation and reactive oxygen species (ros) generation including lipid peroxidation and apoptosis were compared. |
2011-07-14 |
2023-08-12 |
human |
| Rajendra Sharma, Bryan Ellis, Abha Sharm. Role of alpha class glutathione transferases (GSTs) in chemoprevention: GSTA1 and A4 overexpressing human leukemia (HL60) cells resist sulforaphane and curcumin induced toxicity. Phytotherapy research : PTR. vol 25. issue 4. 2011-07-05. PMID:20857431. |
after analysing the expression and activities of the respective gst isozymes, the effects of sfn and cur on the extent of lpo, cytotoxicity and apoptosis were compared in empty vector (vt), hgsta1-1 and mgsta4-4 expressing hl60 cells. |
2011-07-05 |
2023-08-12 |
human |
| Rajendra Sharma, Bryan Ellis, Abha Sharm. Role of alpha class glutathione transferases (GSTs) in chemoprevention: GSTA1 and A4 overexpressing human leukemia (HL60) cells resist sulforaphane and curcumin induced toxicity. Phytotherapy research : PTR. vol 25. issue 4. 2011-07-05. PMID:20857431. |
the ectopic expression of hgsta1-1 and mgsta4-4 isozymes provided resistance to sfn and cur induced cytotoxicity and apoptosis through a significant suppression of lpo in these cells. |
2011-07-05 |
2023-08-12 |
human |