| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Lokesh Agrawal, Jean-Pierre Louboutin, Beverly A S Reyes, Elisabeth J Van Bockstaele, David S Straye. HIV-1 Tat neurotoxicity: a model of acute and chronic exposure, and neuroprotection by gene delivery of antioxidant enzymes. Neurobiology of disease. vol 45. issue 2. 2012-05-18. PMID:22036626. |
both acute and chronic tat exposure induced lipid peroxidation and neuronal apoptosis. |
2012-05-18 |
2023-08-12 |
rat |
| Gaffari Türk, Ali Osman Ceribaşı, Engin Sahna, Ahmet Ateşşahi. Lycopene and ellagic acid prevent testicular apoptosis induced by cisplatin. Phytomedicine : international journal of phytotherapy and phytopharmacology. vol 18. issue 5. 2012-05-17. PMID:20739166. |
however, combined treatments of lc or ea in addition to cp tended to prevent the cp-induced testicular apoptosis, histopathological lesions and lipid peroxidation. |
2012-05-17 |
2023-08-12 |
rat |
| Daniela Impellizzeri, Emanuela Esposito, Emanuela Mazzon, Irene Paterniti, Rosanna Di Paola, Placido Bramanti, Valeria Maria Morittu, Antonio Procopio, Enzo Perri, Domenico Britti, Salvatore Cuzzocre. The effects of a polyphenol present in olive oil, oleuropein aglycone, in an experimental model of spinal cord injury in mice. Biochemical pharmacology. vol 83. issue 10. 2012-05-14. PMID:22342994. |
the treatment with oleuropein aglycone significantly decreased: (1) histological damage, (2) motor recovery, (3) nuclear factor (nf)-κb expression and ikb-α degradation, (4) protein kinase a (pka) activity and expression, (5) pro-inflammatory cytokines production such as tumor necrosis factor (tnf-α) and interleukin-1β (il-1β), 6) inducible nitric oxide synthase (inos) expression, (7) neutrophil infiltration, (8) lipid peroxidation, (9) nitrotyrosine and poly-adp-ribose (par) formation, (10) glial cell-derived neurotrophic factor (gdnf) levels, (11) apoptosis (tunel staining, fas ligand expression, caspase 3, bax and bcl-2 expression). |
2012-05-14 |
2023-08-12 |
mouse |
| Ruiyue Yang, Junbo Wang, Zhigang Liu, Xinrong Pei, Xiaolong Han, Yong L. Antioxidant effect of a marine oligopeptide preparation from chum salmon (Oncorhynchus keta) by enzymatic hydrolysis in radiation injured mice. Marine drugs. vol 9. issue 11. 2012-04-20. PMID:22163188. |
these effects may be caused by augmentation of the activities of antioxidant enzymes, such as sod and gsh-px, reduction of the lipid peroxidation (mda level) in liver, and protection against radiation-induced apoptosis. |
2012-04-20 |
2023-08-12 |
mouse |
| Farhat Jabeen, Abdul Shakoor Chaudhr. Effects of cadmium chloride and sodium selenite alone or in combination on the liver of male Sprague-Dawley rats assessed by different assays. Biological trace element research. vol 143. issue 2. 2012-04-12. PMID:21213067. |
the cd group showed increased dna damage, apoptosis and hepatic levels of lipid peroxidation and altered histology. |
2012-04-12 |
2023-08-12 |
rat |
| Masaharu Hayashi, Rie Miyata, Naoyuki Tanum. Oxidative stress in developmental brain disorders. Advances in experimental medicine and biology. vol 724. 2012-04-10. PMID:22411250. |
next, congenital metabolic errors, apoptosis due to lipid peroxidation seemed to cause neuronal damage in neuronal ceroid-lipofuscinosis. |
2012-04-10 |
2023-08-12 |
Not clear |
| B Chhunchha, N Fatma, B Bhargavan, E Kubo, A Kumar, D P Sing. Specificity protein, Sp1-mediated increased expression of Prdx6 as a curcumin-induced antioxidant defense in lens epithelial cells against oxidative stress. Cell death & disease. vol 2. 2012-03-16. PMID:22113199. |
curcumin enhanced sp1 and prdx6 mrna and protein expression in a concentration-dependent manner, as evidenced by western and real-time pcr analyses, and thereby negatively regulated ros-mediated apoptosis by blunting ros expression and lipid peroxidation. |
2012-03-16 |
2023-08-12 |
human |
| Alma Rus, Francisco Molina, M Ángeles Peinado, M Luisa Del Mora. Nitric oxide averts hypoxia-induced damage during reoxygenation in rat heart. Microscopy research and technique. vol 74. issue 12. 2012-03-15. PMID:21538695. |
the rats were studied at 0 h, 12 h, and 5 days of reoxygenation, analysing parameters of cell, and tissue damage (lipid peroxidation, apoptosis, and protein nitration), as well as in situ nos activity and no production (nox). |
2012-03-15 |
2023-08-12 |
rat |
| Chin-Ching Wu, Cheng-Chieh Yen, kuan-I Lee, Chin-Chuan Su, Feng-Cheng Tang, Kuo-Liang Chen, Yi-Chang Su, Ya-Wen Che. Involvement of oxidative stress-induced ERK/JNK activation in the Cu(2+)/pyrrolidine dithiocarbamate complex-triggered mitochondria-regulated apoptosis in pancreatic β-cells. Toxicology letters. vol 208. issue 3. 2012-03-15. PMID:22085843. |
cu(2+)/pdtc complex could also increase the lpo and decrease the intracellular reduced gsh levels, and display several features of apoptosis signals including: increase in sub-g1 cell population, annexin-v binding, and caspase-3 activity, mitochondrial dysfunctions, and the activation of parp and caspase cascades, which accompanied with the marked increase the intracellular cu(2+) levels. |
2012-03-15 |
2023-08-12 |
Not clear |
| M A Shupik, A F Vanin, A V Alessenk. Interaction of the nitric oxide signaling system with the sphingomyelin cycle and peroxidation on transmission of toxic signal of tumor necrosis factor-α in ischemia-reperfusion. Biochemistry. Biokhimiia. vol 76. issue 11. 2012-03-15. PMID:22117546. |
the role of a proinflammatory cytokine tnf-α in apoptosis and ischemia-reperfusion and mechanisms of its cytotoxic action, which involve nitric oxide, the sphingomyelin cycle, and lipid peroxidation are discussed. |
2012-03-15 |
2023-08-12 |
Not clear |
| Masanori Horie, Haruhisa Kato, Shigehisa Endoh, Katsuhide Fujita, Keiko Nishio, Lilian Kaede Komaba, Hiroko Fukui, Ayako Nakamura, Arisa Miyauchi, Tetsuya Nakazato, Shinichi Kinugasa, Yasukazu Yoshida, Yoshihisa Hagihara, Yasuo Morimoto, Hitoshi Iwahash. Evaluation of cellular influences of platinum nanoparticles by stable medium dispersion. Metallomics : integrated biometal science. vol 3. issue 11. 2012-02-29. PMID:21804981. |
cell viability (mtt assay), cell proliferation (clonogenic assay), apoptosis induction (caspase-3 activity), intracellular ros level (dcfh assay), and lipid peroxidation level (dppp assay) were measured as markers of cellular influences. |
2012-02-29 |
2023-08-12 |
Not clear |
| Hirofumi Matsui, Yumiko Nagano, Osamu Shimokawa, Tsuyoshi Kaneko, Kanho Rai, Jumpei Udo, Aki Hirayama, Yukio Nakamura, Hiroko P Indo, Hideyuki J Majima, Ichinosuke Hyod. Gastric acid induces mitochondrial superoxide production and lipid peroxidation in gastric epithelial cells. Journal of gastroenterology. vol 46. issue 10. 2012-02-22. PMID:21789481. |
we hypothesized that gastric acid may disrupt mitochondrial transmembrane potential and induce the production of superoxide in mitochondria, which subsequently may induce lipid peroxidation and apoptosis in gastric mucosal cells. |
2012-02-22 |
2023-08-12 |
Not clear |
| Menaka C Thounaojam, Ravirajsinh N Jadeja, Mayur Valodkar, Padamanabhi S Nagar, Ranjitsinh V Devkar, Sonal Thakor. Oxidative stress induced apoptosis of human lung carcinoma (A549) cells by a novel copper nanorod formulation. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 49. issue 11. 2012-02-13. PMID:21820027. |
also, reduced glutathione (gsh), lipid peroxidation (lpo), cellular oxidative stress (rhodamine 123 florescence) and apoptosis (annexin v fitc/propidium iodide staining) were also investigated in control and treated cells. |
2012-02-13 |
2023-08-12 |
human |
| Indika B Gawarammana, Nicholas A Buckle. Medical management of paraquat ingestion. British journal of clinical pharmacology. vol 72. issue 5. 2012-02-09. PMID:21615775. |
paraquat generates reactive oxygen species which cause cellular damage via lipid peroxidation, activation of nf-κb, mitochondrial damage and apoptosis in many organs. |
2012-02-09 |
2023-08-12 |
human |
| Qin-li Zhang, Fang Wang, Ying-tao Shi, Lin-ping Wang, Ling Zhang, Hong-mei Zhang, Jing Wang, Qiu-ying Li, Qiao Ni. [Lipid peroxidation injury and endoplasmic reticulum stress in Al-induced apoptosis]. Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases. vol 26. issue 3. 2012-01-23. PMID:18761791. |
[lipid peroxidation injury and endoplasmic reticulum stress in al-induced apoptosis]. |
2012-01-23 |
2023-08-12 |
Not clear |
| Qin-li Zhang, Fang Wang, Ying-tao Shi, Lin-ping Wang, Ling Zhang, Hong-mei Zhang, Jing Wang, Qiu-ying Li, Qiao Ni. [Lipid peroxidation injury and endoplasmic reticulum stress in Al-induced apoptosis]. Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases. vol 26. issue 3. 2012-01-23. PMID:18761791. |
to study the role of lipid peroxidation injury and endoplasmic reticulum stress in al-induced apoptosis. |
2012-01-23 |
2023-08-12 |
Not clear |
| Shumin Zhang, Xuexi Tang, Jingwei Tian, Chunmei Li, Guanbo Zhang, Wanglin Jiang, Zunting Zhan. Cardioprotective effect of sulphonated formononetin on acute myocardial infarction in rats. Basic & clinical pharmacology & toxicology. vol 108. issue 6. 2012-01-09. PMID:21232020. |
a possible mechanism for the protective effect is the elevated expression of endogenous antioxidant defence enzymes degraded lipid peroxidation products and improved energy metholism of cardiac mitochondrial, thus attenuating cardiocyte apoptosis. |
2012-01-09 |
2023-08-12 |
rat |
| Marta Kubera, Ewa Obuchowicz, Lisa Goehler, Joanna Brzeszcz, Michael Mae. In animal models, psychosocial stress-induced (neuro)inflammation, apoptosis and reduced neurogenesis are associated to the onset of depression. Progress in neuro-psychopharmacology & biological psychiatry. vol 35. issue 3. 2012-01-06. PMID:20828592. |
external stress-induced depression-like behaviors are associated with a) increased interleukin-(il)1β, tumor necrosis factor-α, il-6, nuclear factor κb, cyclooxygenase-2, expression of toll-like receptors and lipid peroxidation; b) antineurogenic effects and reduced brain-derived neurotrophic factor (bdnf) levels; and c) apoptosis with reduced levels of bcl-2 and bag1 (bcl-2 associated athanogene 1), and increased levels of caspase-3. |
2012-01-06 |
2023-08-12 |
Not clear |
| Mustafa Sönmez, Gaffari Türk, Ali Osman Çeribaşı, Fatih Sakin, Ahmet Ateşşahi. Attenuating effect of lycopene and ellagic acid on 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced spermiotoxicity and testicular apoptosis. Drug and chemical toxicology. vol 34. issue 4. 2012-01-05. PMID:21714773. |
sperm motility, concentration, and abnormal sperm rate in epididymal tissue, testicular tissue lipid peroxidation (lpo), antioxidant enzyme activity, histopathological changes, and apoptosis (i.e., bax and bcl-2 proteins) were determined. |
2012-01-05 |
2023-08-12 |
rat |
| Mustafa Sönmez, Gaffari Türk, Ali Osman Çeribaşı, Fatih Sakin, Ahmet Ateşşahi. Attenuating effect of lycopene and ellagic acid on 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced spermiotoxicity and testicular apoptosis. Drug and chemical toxicology. vol 34. issue 4. 2012-01-05. PMID:21714773. |
tcdd-induced lipid peroxidation leads to functional and structural damages, as well as apoptosis, in spermatogenic cells of rats. |
2012-01-05 |
2023-08-12 |
rat |