| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Rong-Chang Chen, Gui-Bo Sun, Qiang Zhang, Zu-Guang Ye, Xiao-Bo Su. [Advances in studies on toxicity of aconite]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 38. issue 8. 2013-09-09. PMID:23944022. |
its toxicological mechanism main shows in the effect on voltage-dependent sodium channels, release of neurotransmitters and changes in receptors, promotion of lipid peroxidation and cell apoptosis in heart, liver and other tissues. |
2013-09-09 |
2023-08-12 |
Not clear |
| Ceren Kencebay, Narin Derin, Ozlem Ozsoy, Dijle Kipmen-Korgun, Gamze Tanriover, Nihal Ozturk, Goksun Basaranlar, Piraye Yargicoglu-Akkiraz, Berna Sozen, Aysel Aga. Merit of quinacrine in the decrease of ingested sulfite-induced toxic action in rat brain. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 52. 2013-09-06. PMID:23168241. |
we aimed at investigating the effects of sulfite-induced lipid peroxidation and apoptosis mediated by secretory phospholipase a2 (spla2) on somatosensory evoked potentials (sep) alterations in rats. |
2013-09-06 |
2023-08-12 |
rat |
| Maria Wide. Bystander effect induced by UV radiation; why should we be interested? Postepy higieny i medycyny doswiadczalnej (Online). vol 66. 2013-09-05. PMID:23175338. |
reactive oxygen and nitrogen species generated by uv in exposed cells induce bystander effects in non-exposed cells, such as reduction in clonogenic cell survival and delayed cell death, oxidative dna damage and gene mutations, induction of micronuclei, lipid peroxidation and apoptosis. |
2013-09-05 |
2023-08-12 |
human |
| W Niżański, A Partyka, T Rijsselaer. Use of fluorescent stainings and flow cytometry for canine semen assessment. Reproduction in domestic animals = Zuchthygiene. vol 47 Suppl 6. 2013-09-05. PMID:23279503. |
the analysis of events detected on dot plots gives accurate and highly reliable information on membrane integrity, acrosomal status, mitochondrial activity, capacitation status, lipid peroxidation, apoptosis and dna damage. |
2013-09-05 |
2023-08-12 |
Not clear |
| Yaremi Quiros, Penelope D Sánchez-González, Francisco J López-Hernández, Ana I Morales, José M López-Novo. Cardiotrophin-1 administration prevents the renal toxicity of iodinated contrast media in rats. Toxicological sciences : an official journal of the Society of Toxicology. vol 132. issue 2. 2013-09-03. PMID:23335628. |
the severity of cin was assessed by the measurement of renal function; renal histological damage; urinary excretion of markers of tubular damage, including n-acetyl beta glucosaminidase (nag), kidney injury molecule 1 (kim-1), and plasminogen activator inhibitor 1; lipid peroxidation; and renal apoptosis. |
2013-09-03 |
2023-08-12 |
rat |
| Sheng-Hsien Chen, Mao-Tsun Lin, Ching-Ping Chan. Ischemic and oxidative damage to the hypothalamus may be responsible for heat stroke. Current neuropharmacology. vol 11. issue 2. 2013-09-02. PMID:23997749. |
compared with normothermic controls, rodents with heatstroke have higher hypothalamic values of cellular ischemia (e.g., glutamate and lactate-to-pyruvate ratio) and damage (e.g., glycerol) markers, pro-oxidant enzymes (e.g., lipid peroxidation and glutathione oxidation), proinflammatory cytokines (e.g., interleukin-1β and tumor necrosis factor-α), inducible nitric oxide synthase-dependent nitric oxide, and an indicator for the accumulation of polymorphonuclear leukocytes (e.g., myeloperoxidase activity), as well as neuronal damage (e.g., apoptosis, necrosis, and autophagy) after heatstroke. |
2013-09-02 |
2023-08-12 |
Not clear |
| Dilip Shah, Sangita Sah, Ajay Wanchu, Mei X Wu, Archana Bhatnaga. Altered redox state and apoptosis in the pathogenesis of systemic lupus erythematosus. Immunobiology. vol 218. issue 4. 2013-08-27. PMID:22940256. |
the lymphocyte apoptosis and activated caspase-3 expression were negatively associated with intracellular levels of gsh and redox state and positively associated with the elevated levels of multiple oxidative stress markers; ros and lipid peroxidation measured as malondialdehyde (mda). |
2013-08-27 |
2023-08-12 |
Not clear |
| Binan Lu, Yousong Xu, Lina Xu, Xiaonan Cong, Lianhong Yin, Hua Li, Jinyong Pen. Mechanism investigation of dioscin against CCl4-induced acute liver damage in mice. Environmental toxicology and pharmacology. vol 34. issue 2. 2013-06-25. PMID:22516057. |
these protective effects against ccl(4) induced acute liver damage might be through inhibiting lipid peroxidation, inflammatory cytokines, necrosis and apoptosis, and dioscin shows promise for development toward the treatment of acute chemically mediated liver injury. |
2013-06-25 |
2023-08-12 |
mouse |
| Quanfang Huang, Renbin Huang, Shijun Zhang, Jun Lin, Ling Wei, Min He, Lang Zhuo, Xing Li. Protective effect of genistein isolated from Hydrocotyle sibthorpioides on hepatic injury and fibrosis induced by chronic alcohol in rats. Toxicology letters. vol 217. issue 2. 2013-06-19. PMID:23274713. |
mechanistically, studies showed that genistein markedly reduced lipid peroxidation, recruited the anti-oxidative defense system, inhibited cyp2el activity, promoted extracellular matrix degradation by modulating the levels of tissue inhibitor of matrix metalloproteinase-1 and matrix metalloproteinase-2, induced hsc apoptosis by down-regulating b-cell lymphoma 2 mrna, and inhibited the expression of α-smooth muscle actin and transforming growth factor β(1) proteins. |
2013-06-19 |
2023-08-12 |
rat |
| Hai-Dong Yao, Qiong Wu, Zi-Wei Zhang, Jiu-Li Zhang, Shu Li, Jia-Qiang Huang, Fa-Zheng Ren, Shi-Wen Xu, Xiao-Long Wang, Xin Gen Le. Gene expression of endoplasmic reticulum resident selenoproteins correlates with apoptosis in various muscles of se-deficient chicks. The Journal of nutrition. vol 143. issue 5. 2013-06-18. PMID:23514769. |
our objectives were to investigate: 1) if dietary se deficiency induced different amounts of oxidative stress, lipid peroxidation, and cell apoptosis in 3 skeletal muscles; and 2) if the distribution and expression of 4 endoplasmic reticulum (er) resident selenoprotein genes (sepn1, selk, sels, and selt) were related to oxidative damages in these muscles. |
2013-06-18 |
2023-08-12 |
Not clear |
| Hai-Dong Yao, Qiong Wu, Zi-Wei Zhang, Jiu-Li Zhang, Shu Li, Jia-Qiang Huang, Fa-Zheng Ren, Shi-Wen Xu, Xiao-Long Wang, Xin Gen Le. Gene expression of endoplasmic reticulum resident selenoproteins correlates with apoptosis in various muscles of se-deficient chicks. The Journal of nutrition. vol 143. issue 5. 2013-06-18. PMID:23514769. |
two groups of day-old layer chicks (n = 60/group) were fed a corn-soy basal diet (33 μg se/kg; produced in the se-deficient area of heilongjiang, china) or the diet supplemented with se (as sodium selenite) at 0.15 mg/kg for 55 d. dietary se deficiency resulted in accelerated (p < 0.05) cell apoptosis that was associated with decreased glutathione peroxidase activity and elevated lipid peroxidation in these muscles. |
2013-06-18 |
2023-08-12 |
Not clear |
| Xiao-Qing Tang, Yuan-Yuan Zhuang, Ping Zhang, Heng-Rong Fang, Cheng-Fang Zhou, Hong-Feng Gu, Hui Zhang, Chun-Yan Wan. Formaldehyde impairs learning and memory involving the disturbance of hydrogen sulfide generation in the hippocampus of rats. Journal of molecular neuroscience : MN. vol 49. issue 1. 2013-06-12. PMID:23108488. |
we found that the intracerebroventricular injection of fa in rats impairs the function of learning and memory in the morris water maze and novel object recognition test and increases the formation of apoptosis and lipid peroxidation in the hippocampus. |
2013-06-12 |
2023-08-12 |
rat |
| Riham S Said, Ahmed S Nada, Ebtehal El-Demerdas. Sodium selenite improves folliculogenesis in radiation-induced ovarian failure: a mechanistic approach. PloS one. vol 7. issue 12. 2013-05-24. PMID:23236409. |
in conclusion, sodium selenite showed a radioprotective effect and improved folliculogenesis through increasing ovarian granulosa cells proliferation, estradiol and fsh secretion, and gpx activity, whilst decreasing lipid peroxidation and oxidative stress, leading to inhibition of the apoptosis pathway through decreasing the expressions of caspase 3 and cytochrome c. |
2013-05-24 |
2023-08-12 |
rat |
| Ismail Ben Mosbah, Yann Mouchel, Julie Pajaud, Catherine Ribault, Catherine Lucas, Alexis Laurent, Karim Boudjema, Fabrice Morel, Anne Corlu, Philippe Compagno. Pretreatment with mangafodipir improves liver graft tolerance to ischemia/reperfusion injury in rat. PloS one. vol 7. issue 11. 2013-05-20. PMID:23226251. |
the protective effect of mndpdp was associated with a significant decrease of lipid peroxidation, mitochondrial damage, and apoptosis. |
2013-05-20 |
2023-08-12 |
rat |
| Xiao-fei Liu, Zhi-peng Li, Feng Tie, Ning Liu, Zi-wei Zhang, Shi-wen X. Effects of manganese-toxicity on immune-related organs of cocks. Chemosphere. vol 90. issue 7. 2013-05-16. PMID:23177007. |
it indicated that mn exposure resulted in oxidative damage of birds immune system by altering antioxidant defense enzyme systems, lipid peroxidation, and apoptosis. |
2013-05-16 |
2023-08-12 |
Not clear |
| Pelin Arda-Pirincci, Fusun Oztay, Bertan Boran Bayrak, Refiye Yanardag, Sehnaz Bolken. Teduglutide, a glucagon-like peptide 2 analogue: a novel protective agent with anti-apoptotic and anti-oxidant properties in mice with lung injury. Peptides. vol 38. issue 2. 2013-05-14. PMID:23059393. |
teduglutide pretreatment regressed the structural damage, cell apoptosis and oxidative stress by reducing lipid peroxidation in mice received tnf-α/act d. glp-2 receptors were present on the cell membrane of type ii pneumocytes and interstitial cells. |
2013-05-14 |
2023-08-12 |
mouse |
| Hiroko P Indo, Osamu Inanami, Tomoko Koumura, Shigeaki Suenaga, Hsiu-Chuan Yen, Shizuko Kakinuma, Ken-Ichiro Matsumoto, Ikuo Nakanishi, William St Clair, Daret K St Clair, Hirofumi Matsui, Richard Cornette, Oleg Gusev, Takashi Okuda, Yasuhito Nakagawa, Toshihiko Ozawa, Hideyuki J Majim. Roles of mitochondria-generated reactive oxygen species on X-ray-induced apoptosis in a human hepatocellular carcinoma cell line, HLE. Free radical research. vol 46. issue 8. 2013-05-09. PMID:22656864. |
mitochondrial reactive oxygen species (ros), lipid peroxidation and apoptosis were examined as a function of time following 18.8 gy x-ray irradiation. |
2013-05-09 |
2023-08-12 |
human |
| Hiroko P Indo, Osamu Inanami, Tomoko Koumura, Shigeaki Suenaga, Hsiu-Chuan Yen, Shizuko Kakinuma, Ken-Ichiro Matsumoto, Ikuo Nakanishi, William St Clair, Daret K St Clair, Hirofumi Matsui, Richard Cornette, Oleg Gusev, Takashi Okuda, Yasuhito Nakagawa, Toshihiko Ozawa, Hideyuki J Majim. Roles of mitochondria-generated reactive oxygen species on X-ray-induced apoptosis in a human hepatocellular carcinoma cell line, HLE. Free radical research. vol 46. issue 8. 2013-05-09. PMID:22656864. |
authentic mnsod, but not mnsod lacking mts, protected against mitochondrial ros, lipid peroxidation and apoptosis. |
2013-05-09 |
2023-08-12 |
human |
| Celia Casares, Rafael Ramírez-Camacho, Almudena Trinidad, Amaya Roldán, Eduardo Jorge, José Ramón García-Berroca. Reactive oxygen species in apoptosis induced by cisplatin: review of physiopathological mechanisms in animal models. European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery. vol 269. issue 12. 2013-05-03. PMID:22584749. |
several mechanisms are believed to mediate cisplatin-induced apoptosis: binding of cisplatin to guanine bases on dna and the formation of inter- and intra-strand chain cross-linking, generation of reactive oxygen species (ros) with increased lipid peroxidation and ca(2+) influx and, finally, inflammation mediated by cisplatin. |
2013-05-03 |
2023-08-12 |
Not clear |
| Mustafa Kayan, Mustafa Nazıroğlu, Ishak Suat Ovey, Mehmet Aykur, Abdülhadi Cihangir Uğuz, Vedat Ali Yürekl. Non-ionic contrast media induces oxidative stress and apoptosis through Ca²⁺ influx in human neutrophils. The Journal of membrane biology. vol 245. issue 12. 2013-05-02. PMID:22903554. |
serum and neutrophil lipid peroxidation, apoptosis and intracellular ca²⁺ concentrations levels were higher in the cm group than in controls. |
2013-05-02 |
2023-08-12 |
human |