| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sibylle Grub, Urs A Boelsterli, Christian Trendelenburg, Wolfgang E Trommer, Armin Wol. Lipid peroxidation-independent mechanisms of vitamin e-mediated protection against cyclosporine a-induced hepatocellular toxicity and apoptosis. Toxicology mechanisms and methods. vol 13. issue 3. 2012-10-02. PMID:20021159. |
in contrast, the classical chain-breaking lipid peroxidation inhibitor alpha-tocopherol was able to rescue cells from csa-induced cytotoxicity and apoptosis. |
2012-10-02 |
2023-08-12 |
rat |
| Xia Xie, Hai-Tao Wang, Chun-Li Li, Xu-Hong Gao, Jin-Lan Ding, Hai-Hua Zhao, Yong-Li L. Ginsenoside Rb1 protects PC12 cells against β-amyloid-induced cell injury. Molecular medicine reports. vol 3. issue 4. 2012-10-02. PMID:21472290. |
to examine the potential protective effect of grb1 in aβ25-35-induced cytotoxicity, cells were pre-treated with grb1 for 24 h, and then aβ25-35 was added to the medium for an additional 24 h. exposure to aβ led to the accumulation of ros and lipid peroxidation, eventually causing a decrease in the bcl-2/bax ratio, caspase-3 activation, cell apoptosis and cell death. |
2012-10-02 |
2023-08-12 |
Not clear |
| Chan-Min Liu, Yuan-Lin Zheng, Jun Lu, Zi-Feng Zhang, Shao-Hua Fan, Dong-Mei Wu, Jie-Qiong M. Quercetin protects rat liver against lead-induced oxidative stress and apoptosis. Environmental toxicology and pharmacology. vol 29. issue 2. 2012-10-02. PMID:21787598. |
in conclusion, these data suggest that quercetin protects the rat liver from lead-induced injury by attenuating lipid peroxidation, renewing the activities of antioxidant enzymes and inhibiting apoptosis. |
2012-10-02 |
2023-08-12 |
rat |
| Shuhua Yang, Ziwei Zhang, Jianbin He, Jinlong Li, Jiuli Zhang, Houjuan Xing, Shiwen X. Ovarian toxicity induced by dietary cadmium in hen. Biological trace element research. vol 148. issue 1. 2012-10-02. PMID:22367677. |
it indicated that cd exposure resulted in oxidative damage of hens' ovary tissue by altering antioxidant defense enzyme systems, lipid peroxidation, apoptosis and endocrine disturbance which may be possible underlying reproductive toxicity mechanisms induced by cd. |
2012-10-02 |
2023-08-12 |
Not clear |
| Jin-Ying Zhao, Yan-Wei Li, Lin L. [The role of iron and hepcidin in hepatic fibrosis]. Sheng li ke xue jin zhan [Progress in physiology]. vol 41. issue 3. 2012-10-01. PMID:21416977. |
iron is proposed to play a role in promoting hepatic fibrosis by various mechanisms, including iron-catalyzed production of free radical and lipid peroxidation, alteration of essential biomolecules, triggering cell apoptosis and necrosis, and activation and transformation of the hepatic stellate cell into a myofibroblastic cell. |
2012-10-01 |
2023-08-12 |
Not clear |
| H Wu, D Wang, Z Shu, H Zhou, H Zuo, S Wang, Y Li, X Xu, N Li, R Pen. Cytokines produced by microwave-radiated Sertoli cells interfere with spermatogenesis in rat testis. Andrologia. vol 44 Suppl 1. 2012-09-27. PMID:22211786. |
these up-regulated cytokines can induce apoptosis and lipid peroxidation in the membrane of germ cells. |
2012-09-27 |
2023-08-12 |
rat |
| Robert Pazdro, John R Burges. Differential effects of α-tocopherol and N-acetyl-cysteine on advanced glycation end product-induced oxidative damage and neurite degeneration in SH-SY5Y cells. Biochimica et biophysica acta. vol 1822. issue 4. 2012-09-24. PMID:22261284. |
however, vitamin e has been studied in cell culture systems with primary focus on apoptosis and lipid peroxidation, while its influences on age-induced protein and dna oxidation, intracellular antioxidant status and cell morphology remain largely unknown. |
2012-09-24 |
2023-08-12 |
Not clear |
| WeiNa Xu, WenBin Liu, KangLe Lu, YangYang Jiang, GuiFeng L. Effect of trichlorfon on oxidative stress and hepatocyte apoptosis of Carassius auratus gibelio in vivo. Fish physiology and biochemistry. vol 38. issue 3. 2012-09-17. PMID:21986809. |
the current study revealed that trichlorfon influenced fish plasma antioxidative status, caused lipid peroxidation (lpo) then resulted in hepatocytes apoptosis. |
2012-09-17 |
2023-08-12 |
cat |
| Jin-Xia Zhai, Xing-Hua Wang, Zhao-Xiang Zhang, Li-Wei Zou, Shu-Shu Din. [Studying the lipid peroxidation index, morphology and apoptosis in testis of male BALB/c mice exposed to polybrominated diphenyl ether (BDE-209)]. Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases. vol 29. issue 4. 2012-09-10. PMID:21941785. |
[studying the lipid peroxidation index, morphology and apoptosis in testis of male balb/c mice exposed to polybrominated diphenyl ether (bde-209)]. |
2012-09-10 |
2023-08-12 |
mouse |
| Nizar Abd Manan, Norazlina Mohamed, Ahmad Nazrun Shui. Effects of Low-Dose versus High-Dose γ-Tocotrienol on the Bone Cells Exposed to the Hydrogen Peroxide-Induced Oxidative Stress and Apoptosis. Evidence-based complementary and alternative medicine : eCAM. vol 2012. 2012-09-10. PMID:22956976. |
this study was conducted to investigate the effects of γ-tocotrienol on lipid peroxidation, antioxidant enzymes activities, and apoptosis of osteoblast exposed to hydrogen peroxide (h(2)o(2)). |
2012-09-10 |
2023-08-12 |
cat |
| Su-juan Zhang, Dan Sun, Jin-bo Hao, Yong-Feng Wei, Ling-feng Yin, Xiao Li. The effect of dietary soyabean isoflavones on photodynamic therapy in K562 leukemia cells. Journal of photochemistry and photobiology. B, Biology. vol 110. 2012-08-06. PMID:22424954. |
the results showed that gen inhibited cell proliferation and enhance cell apoptosis, lipid peroxidation, and dna damage in ala-pdt on k562 cells. |
2012-08-06 |
2023-08-12 |
Not clear |
| Su-juan Zhang, Dan Sun, Jin-bo Hao, Yong-Feng Wei, Ling-feng Yin, Xiao Li. The effect of dietary soyabean isoflavones on photodynamic therapy in K562 leukemia cells. Journal of photochemistry and photobiology. B, Biology. vol 110. 2012-08-06. PMID:22424954. |
however, da did not enhance cell apoptosis, lipid peroxidation, and dna damage in ala-pdt. |
2012-08-06 |
2023-08-12 |
Not clear |
| Masashi Takahash. Oxidative stress and redox regulation on in vitro development of mammalian embryos. The Journal of reproduction and development. vol 58. issue 1. 2012-07-31. PMID:22450278. |
imbalance of oxidation and reduction causes production of excess ros, which causes the developmental arrest, physical dna damage, apoptosis induction or lipid peroxidation. |
2012-07-31 |
2023-08-12 |
cattle |
| Lalita Sharma, Jagdeep Kaur, Geeta Shukl. Role of oxidative stress and apoptosis in the placental pathology of Plasmodium berghei infected mice. PloS one. vol 7. issue 3. 2012-07-23. PMID:22396790. |
thus, it can be concluded that the placental pathology during malarial infection is mediated by mitochondrial pathway of apoptosis occurring due to augmented lipid peroxidation which may in turn jeopardise the materno-fetal relationship. |
2012-07-23 |
2023-08-12 |
mouse |
| Alicja Winczura, Daria Zdżalik, Barbara Tude. Damage of DNA and proteins by major lipid peroxidation products in genome stability. Free radical research. vol 46. issue 4. 2012-06-26. PMID:22257221. |
modifications of proteins with lpo products may regulate cellular processes like apoptosis, cell signalling and senescence. |
2012-06-26 |
2023-08-12 |
human |
| Z Ireland, M Castillo-Melendez, H Dickinson, R Snow, D W Walke. A maternal diet supplemented with creatine from mid-pregnancy protects the newborn spiny mouse brain from birth hypoxia. Neuroscience. vol 194. 2012-06-25. PMID:21640166. |
this study provides evidence that the neuroprotective capacity of creatine in the hypoxic perinatal brain involves abrogation of lipid peroxidation and apoptosis, possibly through the maintenance of mitochondrial function. |
2012-06-25 |
2023-08-12 |
mouse |
| E M Mil', S M Gurevich, A I Kozachenko, L G Nagler, A A Albantova, L D Fatkullina, E B Burlakov. [Effects of smoking and tumor process on the contents of key proteins of apoptosis and activity of antioxidant enzymes in blood]. Izvestiia Akademii nauk. Seriia biologicheskaia. issue 1. 2012-06-25. PMID:22567868. |
the results suggest a relationship between the components of enzymatic defence and lipid peroxidation and the content of apoptosis regulator proteins in healthy smokers and cancer patients. |
2012-06-25 |
2023-08-12 |
Not clear |
| Helena Viita, Agnieszka Pacholska, Farizan Ahmad, Johanna Tietäväinen, Jonne Naarala, Anna Hyvärinen, Thomas Wirth, Seppo Ylä-Herttual. 15-Lipoxygenase-1 induces lipid peroxidation and apoptosis, and improves survival in rat malignant glioma. In vivo (Athens, Greece). vol 26. issue 1. 2012-06-22. PMID:22210710. |
15-lipoxygenase-1 induces lipid peroxidation and apoptosis, and improves survival in rat malignant glioma. |
2012-06-22 |
2023-08-12 |
rat |
| Yan Li, Xiaodong Ha. Microcystin-LR causes cytotoxicity effects in rat testicular Sertoli cells. Environmental toxicology and pharmacology. vol 33. issue 2. 2012-06-12. PMID:22301162. |
we examined the decrease of mitochondrial membrane potential (mmp), the increase of reactive oxygen species (ros) production, the increase of lipid peroxidation and decrease of superoxide dismutase (sod) activity in sertoli cells after treatment with mc-lr in vitro, and higher expression of caspase-9 and caspase-3, the increase of apoptosis rate. |
2012-06-12 |
2023-08-12 |
rat |
| Mohamed A Lebda, Mahmoud S El-Neweshy, Yasser S El-Saye. Neurohepatic toxicity of subacute manganese chloride exposure and potential chemoprotective effects of lycopene. Neurotoxicology. vol 33. issue 1. 2012-06-04. PMID:22192907. |
mncl(2)-induced lipid peroxidation and perturbation in antioxidant system, increase of acetylcholinesterase, aminotransferases, and decrease alkaline phosphatase, and lactate dehydrogenase activities with hyperglycemia as demonstrated by alzheimer type ii astrocytosis, and periportal hepatic necrosis and apoptosis were prevented by lycopene. |
2012-06-04 |
2023-08-12 |
rat |