| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yasir Hasan Siddique, Wasi Khan, Braj Raj Singh, Alim H Naqv. Synthesis of alginate-curcumin nanocomposite and its protective role in transgenic Drosophila model of Parkinson's disease. ISRN pharmacology. vol 2013. 2013-10-30. PMID:24171120. |
in the present study, the effect of synthesized alginate-curcumin nanocomposite was studied on the climbing ability of the pd model flies, lipid peroxidation, and apoptosis in the brain of pd model flies. |
2013-10-30 |
2023-08-12 |
human |
| A Prosperini, A Juan-García, G Font, M J Rui. Reactive oxygen species involvement in apoptosis and mitochondrial damage in Caco-2 cells induced by enniatins A, A₁, B and B₁. Toxicology letters. vol 222. issue 1. 2013-10-29. PMID:23867914. |
the cytotoxic effects, the generation of reactive oxygen species (ros) and lipid peroxidation (lpo) as well as the cell cycle disruption, the induction of apoptosis and changes in mitochondrial membrane potential (ΔΨm) as a function of increasing time have been determined in human colorectal adenocarcinoma (caco-2) cells after exposure to enniatins (ens) a, a₁, b and b₁. |
2013-10-29 |
2023-08-12 |
human |
| A Prosperini, A Juan-García, G Font, M J Rui. Reactive oxygen species involvement in apoptosis and mitochondrial damage in Caco-2 cells induced by enniatins A, A₁, B and B₁. Toxicology letters. vol 222. issue 1. 2013-10-29. PMID:23867914. |
ens a, a₁, b and b₁ cytotoxicity involved early ros generation that induced lpo oxidative damage, apoptosis and necrosis via the mitochondrial pathway. |
2013-10-29 |
2023-08-12 |
human |
| Massimo Collino, Alessandro Pini, Niccolò Mugelli, Rosanna Mastroianni, Daniele Bani, Roberto Fantozzi, Laura Papucci, Marilena Fazi, Emanuela Masin. Beneficial effect of prolonged heme oxygenase 1 activation in a rat model of chronic heart failure. Disease models & mechanisms. vol 6. issue 4. 2013-10-24. PMID:23592614. |
the ischemic hearts of the hemin-treated animals displayed reduced oxidative stress and apoptosis in comparison with the non-treated rats, as shown by the decreased levels of lipid peroxidation, free-radical-induced dna damage, caspase-3 activity and bax expression. |
2013-10-24 |
2023-08-12 |
rat |
| Nasser Ahmadiasl, Farhad Ghadiri Soufi, Mohammadreza Alipour, Mohammadreza Bonyadi, Farzam Sheikhzadeh, Amirmansour Vatankhah, Iraj Salehi, Mehran Mesgar. Effects of age increment and 36-week exercise training on antioxidant enzymes and apoptosis in rat heart tissue. Journal of sports science & medicine. vol 6. issue 2. 2013-10-23. PMID:24149335. |
few studies have investigated the influence of the most prevalent life-prolonging strategy physical exercise, on the age increment alterations in the myocardial antioxidant enzymes and apoptosis at mid age and to determine whether exercise-induced antioxidant defense system could attenuate lipid peroxidation. |
2013-10-23 |
2023-08-12 |
rat |
| Muneeb U Rehman, Mir Tahir, Abdul Quaiyoom Khan, Rehan Khan, Abdul Lateef, Oday O Hamiza, Farrah Ali, Sarwat Sultan. Diosmin protects against trichloroethylene-induced renal injury in Wistar rats: plausible role of p53, Bax and caspases. The British journal of nutrition. vol 110. issue 4. 2013-10-21. PMID:23402272. |
the animals in groups ii and iii received an oral treatment of dm at doses of 20 and 40 mg/kg body weight, respectively, for twenty consecutive days, while groups i and v were given maize oil (5 ml/kg body weight and dm 40 mg/kg body weight, respectively) for 20 d. the protective effects of dm on tce-induced oxidative stress and caspase-dependent apoptosis were investigated by assaying oxidative stress biomarkers, lipid peroxidation (lpo), serum toxicity markers, alkaline unwinding assay, caspase-3, -7 and -9, bax and p53 expression. |
2013-10-21 |
2023-08-12 |
rat |
| Saurabh Wadhwa, Russell J Mumpe. D-penicillamine and other low molecular weight thiols: review of anticancer effects and related mechanisms. Cancer letters. vol 337. issue 1. 2013-09-16. PMID:23727371. |
some of the mechanisms that have been proposed include a p53 mediated apoptosis, thiyl radical induced dna damage, membrane damage through lipid peroxidation, anti-angiogenic effects induced by inhibition of matrix metalloproteinase enzymes and angiostatin generation. |
2013-09-16 |
2023-08-12 |
Not clear |
| Wan-Jun Hu, Dan-Wei Ma, Ya-Nan Wang, Hong Zhan. [Oxidative damage of volatile oil from Chenopodium ambrosioides on Vicia faba root tip cells]. Ying yong sheng tai xue bao = The journal of applied ecology. vol 23. issue 4. 2013-09-12. PMID:22803477. |
in this study, the methods of soil culture and filter paper culture were adopted to simulate the eluviation and volatilization of the volatile oil from c. ambrosioides, respectively, and to investigate the allelopathy of the volatile oil on the lipid peroxidation and antioxidant enzyme activities of vicia faba root tip cells, with the mechanisms of the induced tip cell apoptosis analyzed. |
2013-09-12 |
2023-08-12 |
Not clear |
| Wan-Jun Hu, Dan-Wei Ma, Ya-Nan Wang, Hong Zhan. [Oxidative damage of volatile oil from Chenopodium ambrosioides on Vicia faba root tip cells]. Ying yong sheng tai xue bao = The journal of applied ecology. vol 23. issue 4. 2013-09-12. PMID:22803477. |
this study showed that the volatile oil from c. ambrosioides could act on its surrounding plants via eluviation and volatilization, making the lipid peroxidation of acceptor plants aggravated and the antioxidant enzyme activities of the plants inhibited, resulting in the oxidative damage and apoptosis of the plant root tip cells, and accordingly, the inhibition of the plant growth. |
2013-09-12 |
2023-08-12 |
Not clear |
| Rong-Chang Chen, Gui-Bo Sun, Qiang Zhang, Zu-Guang Ye, Xiao-Bo Su. [Advances in studies on toxicity of aconite]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 38. issue 8. 2013-09-09. PMID:23944022. |
its toxicological mechanism main shows in the effect on voltage-dependent sodium channels, release of neurotransmitters and changes in receptors, promotion of lipid peroxidation and cell apoptosis in heart, liver and other tissues. |
2013-09-09 |
2023-08-12 |
Not clear |
| Ceren Kencebay, Narin Derin, Ozlem Ozsoy, Dijle Kipmen-Korgun, Gamze Tanriover, Nihal Ozturk, Goksun Basaranlar, Piraye Yargicoglu-Akkiraz, Berna Sozen, Aysel Aga. Merit of quinacrine in the decrease of ingested sulfite-induced toxic action in rat brain. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 52. 2013-09-06. PMID:23168241. |
we aimed at investigating the effects of sulfite-induced lipid peroxidation and apoptosis mediated by secretory phospholipase a2 (spla2) on somatosensory evoked potentials (sep) alterations in rats. |
2013-09-06 |
2023-08-12 |
rat |
| Maria Wide. Bystander effect induced by UV radiation; why should we be interested? Postepy higieny i medycyny doswiadczalnej (Online). vol 66. 2013-09-05. PMID:23175338. |
reactive oxygen and nitrogen species generated by uv in exposed cells induce bystander effects in non-exposed cells, such as reduction in clonogenic cell survival and delayed cell death, oxidative dna damage and gene mutations, induction of micronuclei, lipid peroxidation and apoptosis. |
2013-09-05 |
2023-08-12 |
human |
| W Niżański, A Partyka, T Rijsselaer. Use of fluorescent stainings and flow cytometry for canine semen assessment. Reproduction in domestic animals = Zuchthygiene. vol 47 Suppl 6. 2013-09-05. PMID:23279503. |
the analysis of events detected on dot plots gives accurate and highly reliable information on membrane integrity, acrosomal status, mitochondrial activity, capacitation status, lipid peroxidation, apoptosis and dna damage. |
2013-09-05 |
2023-08-12 |
Not clear |
| Yaremi Quiros, Penelope D Sánchez-González, Francisco J López-Hernández, Ana I Morales, José M López-Novo. Cardiotrophin-1 administration prevents the renal toxicity of iodinated contrast media in rats. Toxicological sciences : an official journal of the Society of Toxicology. vol 132. issue 2. 2013-09-03. PMID:23335628. |
the severity of cin was assessed by the measurement of renal function; renal histological damage; urinary excretion of markers of tubular damage, including n-acetyl beta glucosaminidase (nag), kidney injury molecule 1 (kim-1), and plasminogen activator inhibitor 1; lipid peroxidation; and renal apoptosis. |
2013-09-03 |
2023-08-12 |
rat |
| Sheng-Hsien Chen, Mao-Tsun Lin, Ching-Ping Chan. Ischemic and oxidative damage to the hypothalamus may be responsible for heat stroke. Current neuropharmacology. vol 11. issue 2. 2013-09-02. PMID:23997749. |
compared with normothermic controls, rodents with heatstroke have higher hypothalamic values of cellular ischemia (e.g., glutamate and lactate-to-pyruvate ratio) and damage (e.g., glycerol) markers, pro-oxidant enzymes (e.g., lipid peroxidation and glutathione oxidation), proinflammatory cytokines (e.g., interleukin-1β and tumor necrosis factor-α), inducible nitric oxide synthase-dependent nitric oxide, and an indicator for the accumulation of polymorphonuclear leukocytes (e.g., myeloperoxidase activity), as well as neuronal damage (e.g., apoptosis, necrosis, and autophagy) after heatstroke. |
2013-09-02 |
2023-08-12 |
Not clear |
| Dilip Shah, Sangita Sah, Ajay Wanchu, Mei X Wu, Archana Bhatnaga. Altered redox state and apoptosis in the pathogenesis of systemic lupus erythematosus. Immunobiology. vol 218. issue 4. 2013-08-27. PMID:22940256. |
the lymphocyte apoptosis and activated caspase-3 expression were negatively associated with intracellular levels of gsh and redox state and positively associated with the elevated levels of multiple oxidative stress markers; ros and lipid peroxidation measured as malondialdehyde (mda). |
2013-08-27 |
2023-08-12 |
Not clear |
| Binan Lu, Yousong Xu, Lina Xu, Xiaonan Cong, Lianhong Yin, Hua Li, Jinyong Pen. Mechanism investigation of dioscin against CCl4-induced acute liver damage in mice. Environmental toxicology and pharmacology. vol 34. issue 2. 2013-06-25. PMID:22516057. |
these protective effects against ccl(4) induced acute liver damage might be through inhibiting lipid peroxidation, inflammatory cytokines, necrosis and apoptosis, and dioscin shows promise for development toward the treatment of acute chemically mediated liver injury. |
2013-06-25 |
2023-08-12 |
mouse |
| Quanfang Huang, Renbin Huang, Shijun Zhang, Jun Lin, Ling Wei, Min He, Lang Zhuo, Xing Li. Protective effect of genistein isolated from Hydrocotyle sibthorpioides on hepatic injury and fibrosis induced by chronic alcohol in rats. Toxicology letters. vol 217. issue 2. 2013-06-19. PMID:23274713. |
mechanistically, studies showed that genistein markedly reduced lipid peroxidation, recruited the anti-oxidative defense system, inhibited cyp2el activity, promoted extracellular matrix degradation by modulating the levels of tissue inhibitor of matrix metalloproteinase-1 and matrix metalloproteinase-2, induced hsc apoptosis by down-regulating b-cell lymphoma 2 mrna, and inhibited the expression of α-smooth muscle actin and transforming growth factor β(1) proteins. |
2013-06-19 |
2023-08-12 |
rat |
| Hai-Dong Yao, Qiong Wu, Zi-Wei Zhang, Jiu-Li Zhang, Shu Li, Jia-Qiang Huang, Fa-Zheng Ren, Shi-Wen Xu, Xiao-Long Wang, Xin Gen Le. Gene expression of endoplasmic reticulum resident selenoproteins correlates with apoptosis in various muscles of se-deficient chicks. The Journal of nutrition. vol 143. issue 5. 2013-06-18. PMID:23514769. |
our objectives were to investigate: 1) if dietary se deficiency induced different amounts of oxidative stress, lipid peroxidation, and cell apoptosis in 3 skeletal muscles; and 2) if the distribution and expression of 4 endoplasmic reticulum (er) resident selenoprotein genes (sepn1, selk, sels, and selt) were related to oxidative damages in these muscles. |
2013-06-18 |
2023-08-12 |
Not clear |
| Hai-Dong Yao, Qiong Wu, Zi-Wei Zhang, Jiu-Li Zhang, Shu Li, Jia-Qiang Huang, Fa-Zheng Ren, Shi-Wen Xu, Xiao-Long Wang, Xin Gen Le. Gene expression of endoplasmic reticulum resident selenoproteins correlates with apoptosis in various muscles of se-deficient chicks. The Journal of nutrition. vol 143. issue 5. 2013-06-18. PMID:23514769. |
two groups of day-old layer chicks (n = 60/group) were fed a corn-soy basal diet (33 μg se/kg; produced in the se-deficient area of heilongjiang, china) or the diet supplemented with se (as sodium selenite) at 0.15 mg/kg for 55 d. dietary se deficiency resulted in accelerated (p < 0.05) cell apoptosis that was associated with decreased glutathione peroxidase activity and elevated lipid peroxidation in these muscles. |
2013-06-18 |
2023-08-12 |
Not clear |