| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Qiongmei Guo, Xuefang Du, Yanli Zhao, Dong Zhang, Lihui Yue, Zhenxian Wan. Ischemic postconditioning prevents renal ischemia reperfusion injury through the induction of heat shock proteins in rats. Molecular medicine reports. vol 10. issue 6. 2015-06-19. PMID:25322861. |
ipo attenuated these changes observed in pathology, lipid peroxidation, apoptosis and inflammation. |
2015-06-19 |
2023-08-13 |
rat |
| Qiongmei Guo, Xuefang Du, Yanli Zhao, Dong Zhang, Lihui Yue, Zhenxian Wan. Ischemic postconditioning prevents renal ischemia reperfusion injury through the induction of heat shock proteins in rats. Molecular medicine reports. vol 10. issue 6. 2015-06-19. PMID:25322861. |
in conclusion, this study showed that ipo can attenuate lipid peroxidation, apoptosis and inflammation as well as renal iri by upregulating the expression of hsp70, hsp27 and ho‑1. |
2015-06-19 |
2023-08-13 |
rat |
| Debanjana Chakraborty, Arindam Maity, Tarun Jha, Nirup Bikash Monda. Spermicidal and contraceptive potential of desgalactotigonin: a prospective alternative of nonoxynol-9. PloS one. vol 9. issue 9. 2015-06-16. PMID:25243914. |
lipid peroxidation and induction of apoptosis by dgt on human spermatozoa were also studied. |
2015-06-16 |
2023-08-13 |
human |
| Xiang Hou, Jingfei Zhang, Hussain Ahmad, Hao Zhang, Ziwei Xu, Tian Wan. Evaluation of antioxidant activities of ampelopsin and its protective effect in lipopolysaccharide-induced oxidative stress piglets. PloS one. vol 9. issue 9. 2015-06-10. PMID:25268121. |
ampelopsin also protected pig erythrocytes against aaph-induced apoptosis and hemolysis, decreased total superoxide dismutase activity, and increased lipid peroxidation. |
2015-06-10 |
2023-08-13 |
Not clear |
| Yongde Xu, Hongen Lei, Ruili Guan, Zhezhu Gao, Huixi Li, Lin Wang, Yu Hui, Feng Zhou, Zhongcheng Xi. Prophylactic protective effects and its potential mechanisms of IcarisideII on streptozotocin induced spermatogenic dysfunction. International journal of molecular sciences. vol 15. issue 9. 2015-06-02. PMID:25216341. |
four weeks later, sperm parameters, histopathological changes, testicular lipid peroxidation, antioxidant enzyme activities, and apoptosis index (ai) were evaluated. |
2015-06-02 |
2023-08-13 |
rat |
| Jinfeng Dai, Junhui Shen, Wensheng Pan, Shengrong Shen, Undurti N Da. Effects of polyunsaturated fatty acids on the growth of gastric cancer cells in vitro. Lipids in health and disease. vol 12. 2015-05-14. PMID:23663688. |
these results suggest that pufas induced apoptosis of normal gastric and gastric carcinoma cells could, partly, be attributed to lipid peroxidation process. |
2015-05-14 |
2023-08-12 |
Not clear |
| Pelin Arda-Pirincci, Sehnaz Bolken. The role of epidermal growth factor in prevention of oxidative injury and apoptosis induced by intestinal ischemia/reperfusion in rats. Acta histochemica. vol 116. issue 1. 2015-05-14. PMID:23932386. |
egf treatment to rats with ischemia/reperfusion prevented the ischemia/reperfusion-induced oxidative injury by reducing apoptosis and lipid peroxidation, and by increasing antioxidant enzyme activities. |
2015-05-14 |
2023-08-12 |
human |
| Mirna Situm, Vedrana Bulat, Kristina Majcen, Antea Dzapo, Josip Jezovit. Benefits of controlled ultraviolet radiation in the treatment of dermatological diseases. Collegium antropologicum. vol 38. issue 4. 2015-04-17. PMID:25842770. |
immediate effects are the formation of dna photoproducts and dna damage leading to apoptosis of heratinocytes, langerhans cells, activated t-lymphocytes, neutrophils, macrophages, nk cells, fibroblasts, endothelial cells, and mast-cells, cell membrane damage by lipid peroxidation, and isomerization of chromophores such as urocanic acid. |
2015-04-17 |
2023-08-13 |
Not clear |
| Dalia M Abd El Motteleb, Sally A Selim, Ahmed M Mohame. Differential effects of eugenol against hepatic inflammation and overall damage induced by ischemia/re-perfusion injury. Journal of immunotoxicology. vol 11. issue 3. 2015-04-16. PMID:24099633. |
the results of the present study provide the first evidence that a low dose of eugenol may protect the liver against i/r injury in part by decreasing levels of lipid peroxidation, down-regulating inflammatory mediators, and inhibiting apoptosis, and that a larger dose amplifies the liver injury via oxidant and inflammatory effects. |
2015-04-16 |
2023-08-12 |
rat |
| Yijuan Huang, Wen Liu, Hu Liu, Yanyong Yang, Jianguo Cui, Pei Zhang, Hainan Zhao, Feng He, Ying Cheng, Jin Ni, Jianming Cai, Bailong Li, Fu Ga. Grape seed pro-anthocyanidins ameliorates radiation-induced lung injury. Journal of cellular and molecular medicine. vol 18. issue 7. 2015-04-13. PMID:24758615. |
as shown by electron spin resonance spectrometry, gsps could scavenge hydroxyl radical (•oh) in a dose-dependent manner, which might account for the mitigation of lipid peroxidation and consequent apoptosis of lung cells. |
2015-04-13 |
2023-08-13 |
mouse |
| Sara H Hazem, Mohamed E Shaker, Sylvia A Ashamallah, Tarek M Ibrahi. The novel Janus kinase inhibitor ruxolitinib confers protection against carbon tetrachloride-induced hepatotoxicity via multiple mechanisms. Chemico-biological interactions. vol 220. 2015-02-24. PMID:24973641. |
these comprise (i) reducing infiltration of neutrophils and macrophages, as demonstrated by reducing myeloperoxidase activity and f4/80 positive macrophages; (ii) abating apoptosis of hepatocytes, as denoted by decreasing hepatocytes positive for bax protein; (iii) inhibiting elevation of tnf-α, il-1β and il-10; (iv) inhibiting nf-κb activation and translocation to the nucleus, as visualized immunohistochemically; (v) attenuating activation of the il-23/il-17 pathway via targeting il-17, but not il-23; (vi) antagonizing hepatic oxidative stress by increasing the antioxidant levels (reduced glutathione, glutathione-s-transferase and superoxide dismutase) and decreasing products of lipid peroxidation (malondialdehyde and 4-hydroxynonenal) and total nitrate/nitrite; and (vii) more interestingly, modulating hepatocyte regeneration according to the extent of damage, as quantified by pcna-immunohistochemistry. |
2015-02-24 |
2023-08-13 |
mouse |
| Ellen Klauser, Michael Gülden, Edmund Maser, Sabine Seibert, Hasso Seiber. Additivity, antagonism, and synergy in arsenic trioxide-induced growth inhibition of C6 glioma cells: effects of genistein, quercetin and buthionine-sulfoximine. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 67. 2015-02-09. PMID:24632069. |
this effect was accompanied neither by enhanced radical generation nor lipid peroxidation and was not attributed to apoptosis. |
2015-02-09 |
2023-08-12 |
rat |
| Rajesh Kumar Chaurasia, Sreedevi Balakrishnan, Amit Kunwar, Usha Yadav, Nagesh Bhat, Kshiti Anjaria, Rajesha Nairy, Balvinder Kaur Sapra, Vimal Kumar Jain, K Indira Priyadarsin. Cyto-genotoxicity assessment of potential radioprotector, 3,3'-diselenodipropionic acid (DSePA) in Chinese Hamster Ovary (CHO) cells and human peripheral blood lymphocytes. Mutation research. Genetic toxicology and environmental mutagenesis. vol 774. 2015-01-26. PMID:25440905. |
the mechanistic investigations in cho cells revealed that dsepa pretreatment prevented the radiation induced ros generation, lipid peroxidation and subsequent apoptosis in these cells. |
2015-01-26 |
2023-08-13 |
human |
| Samy Alwarfaly, Akrem Abdulsid, Kevin Hanretty, Fiona Lyal. Paraoxonase 2 protein is spatially expressed in the human placenta and selectively reduced in labour. PloS one. vol 9. issue 5. 2015-01-22. PMID:24816800. |
the paraoxonases (pons 1-3) protect against oxidative damage and lipid peroxidation, modulation of endoplasmic reticulum stress and regulation of apoptosis. |
2015-01-22 |
2023-08-13 |
human |
| Sinem Aras, Gamze Tanriover, Mutay Aslan, Piraye Yargicoglu, Aysel Aga. The role of nitric oxide on visual-evoked potentials in MPTP-induced Parkinsonism in mice. Neurochemistry international. vol 72. 2015-01-09. PMID:24795109. |
the present study aimed to elucidate visual evoked potentials (vep) changes in mptp induced parkinson's disease (pd) and investigate the possible benefical effects of neuronal (n) and inducible (i) nitric oxide synthase (nos) inhibitors on altered veps, lipid peroxidation and apoptosis. |
2015-01-09 |
2023-08-13 |
mouse |
| Yu A Vladimirov, E V Proskurnina, A V Aleksee. Molecular mechanisms of apoptosis. structure of cytochrome c-cardiolipin complex. Biochemistry. Biokhimiia. vol 78. issue 10. 2015-01-06. PMID:24237142. |
one of the functions of cytochrome c in living cells is the initiation of apoptosis by catalyzing lipid peroxidation in the inner mitochondrial membrane, which involves cytochrome c bound with acidic lipids, especially cardiolipin. |
2015-01-06 |
2023-08-12 |
Not clear |
| Abdullah Akpinar, Abdülhadi Cihangir Uğuz, Mustafa Nazıroğl. Agomelatine and duloxetine synergistically modulates apoptotic pathway by inhibiting oxidative stress triggered intracellular calcium entry in neuronal PC12 cells: role of TRPM2 and voltage-gated calcium channels. The Journal of membrane biology. vol 247. issue 5. 2014-12-18. PMID:24682240. |
then pc-12 cells were incubated with agomelatine and duloxetine for 24 h. treatment of cultured pc-12 cells with agomelatine, duloxetine, and their combination results in a protection on apoptosis, caspase-3, caspase-9, mitochondrial membrane depolarization, cytosolic ros production, glutathione peroxidase, reduced glutathione, and lipid peroxidation, values. |
2014-12-18 |
2023-08-12 |
Not clear |
| Lei Li, Yuanyuan Zhang, Juanjuan Ma, Weichong Dong, Qiongtao Song, Jianping Zhang, Li Ch. Salvia miltiorrhiza injection ameliorates renal damage induced by lead exposure in mice. TheScientificWorldJournal. vol 2014. 2014-12-18. PMID:24696648. |
our findings implicate the therapeutic potential of sm injection for pb-induced nephrotoxicity, which were at least partly due to the decrease of pb accumulation, inhibition of lipid peroxidation, and suppression of renal apoptosis. |
2014-12-18 |
2023-08-13 |
mouse |
| Damayanthi Durairajanayagam, Ashok Agarwal, Chloe Ong, Pallavi Prashas. Lycopene and male infertility. Asian journal of andrology. vol 16. issue 3. 2014-12-17. PMID:24675655. |
excessive amounts of reactive oxygen species (ros) cause a state of oxidative stress, which result in sperm membrane lipid peroxidation, dna damage and apoptosis, leading to decreased sperm viability and motility. |
2014-12-17 |
2023-08-12 |
human |
| Yasir Hasan Siddique, Smita Jyoti, Falaq Na. Effect of epicatechin gallate dietary supplementation on transgenic Drosophila model of Parkinson's disease. Journal of dietary supplements. vol 11. issue 2. 2014-11-21. PMID:24670116. |
the objectives of the present work include the study of the effect of eg on the climbing ability, lipid peroxidation, and apoptosis in the brain of pd model flies. |
2014-11-21 |
2023-08-12 |
human |