| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Diana Aguirre-Rueda, Sol Guerra-Ojeda, Martin Aldasoro, Antonio Iradi, Elena Obrador, Angel Ortega, M Dolores Mauricio, Jose Ma Vila, Soraya L Valle. Astrocytes protect neurons from Aβ1-42 peptide-induced neurotoxicity increasing TFAM and PGC-1 and decreasing PPAR-γ and SIRT-1. International journal of medical sciences. vol 12. issue 1. 2015-11-09. PMID:25552918. |
our results indicate that aβ1-42 toxic peptide increases lipid peroxidation, apoptosis and cell death in neurons but not in astrocytes in primary culture. |
2015-11-09 |
2023-08-13 |
Not clear |
| Tessa Lord, Jacinta H Martin, R John Aitke. Accumulation of electrophilic aldehydes during postovulatory aging of mouse oocytes causes reduced fertility, oxidative stress, and apoptosis. Biology of reproduction. vol 92. issue 2. 2015-10-23. PMID:25505195. |
time- and dose-dependent studies revealed that exposure to elevated levels of electrophilic aldehydes causes mitochondrial reactive oxygen species production, lipid peroxidation, loss of mitochondrial membrane potential, and eventual apoptosis within the mii oocyte, presumably as a consequence of electron transport chain collapse following sdha adduction. |
2015-10-23 |
2023-08-13 |
mouse |
| R-H Yang, J Lin, X-H Hou, R Cao, F Yu, H-Q Liu, A-L Ji, X-N Xu, L Zhang, F Wan. Effect of docosahexaenoic acid on hippocampal neurons in high-glucose condition: involvement of PI3K/AKT/nuclear factor-κB-mediated inflammatory pathways. Neuroscience. vol 274. 2015-10-15. PMID:24881575. |
the present study investigated the effects of dha on the lipid peroxidation, the level of inflammatory cytokines and neuron apoptosis in the hippocampal neurons in high-glucose condition. |
2015-10-15 |
2023-08-13 |
Not clear |
| Sooyong Kim, Il-Hwan Kang, Jung-Bum Nam, Yoonchul Cho, Doo-Young Chung, Seung-Hwan Kim, Jeong-Soo Kim, Yong-Deok Cho, Eun-Ki Hong, Nak-Won Sohn, Jung-Won Shi. Ameliorating the effect of astragaloside IV on learning and memory deficit after chronic cerebral hypoperfusion in rats. Molecules (Basel, Switzerland). vol 20. issue 2. 2015-10-13. PMID:25625683. |
as-iv significantly attenuated neuronal apoptosis as well as the levels of superoxide dismutase and lipid peroxidation markers, including malondialdehyde and 4-hydroxy-2-nonenal, in the hippocampus. |
2015-10-13 |
2023-08-13 |
rat |
| Chun Yang, Yi-Kuan Du, Jun Wang, Ping Luan, Qin-Lao Yang, Wen-Hua Huang, Lin Yua. Transplanted Adipose-Derived Stem Cells Ameliorate Testicular Dysfunction In A D-Galactose-Induced Aging Rat Model. Journal of cellular physiology. vol 230. issue 10. 2015-09-21. PMID:25728126. |
serum testosterone level, steroidogenic enzymes (3-β-hydroxysteroid dehydrogenase), and superoxide dismutase (sod) activity decreased significantly in aging rats compared with the control group; serum lipid peroxidation, spermatogenic cell apoptosis, and methane dicarboxylic aldehyde (mda) expression increased significantly. |
2015-09-21 |
2023-08-13 |
rat |
| E A Kose, B Bakar, S K Ayva, K Kilinc, A Apa. Effects of intracisternal tramadol on cerebral and spinal neuronal cells in rat. Minerva anestesiologica. vol 80. issue 8. 2015-09-11. PMID:24326970. |
due to lipid peroxidation (lpo) and myeloperoxidation (mpo) levels are not specific predictors of neuronal damage, these biochemical markers of tissue damage were evaluated together with the histopathological findings of apoptosis. |
2015-09-11 |
2023-08-12 |
rat |
| Xiao Yuan, Xueling Guo, Yan Deng, Die Zhu, Jin Shang, Huiguo Li. Chronic intermittent hypoxia-induced neuronal apoptosis in the hippocampus is attenuated by telmisartan through suppression of iNOS/NO and inhibition of lipid peroxidation and inflammatory responses. Brain research. vol 1596. 2015-08-24. PMID:25463026. |
chronic intermittent hypoxia-induced neuronal apoptosis in the hippocampus is attenuated by telmisartan through suppression of inos/no and inhibition of lipid peroxidation and inflammatory responses. |
2015-08-24 |
2023-08-13 |
rat |
| Xiao Yuan, Xueling Guo, Yan Deng, Die Zhu, Jin Shang, Huiguo Li. Chronic intermittent hypoxia-induced neuronal apoptosis in the hippocampus is attenuated by telmisartan through suppression of iNOS/NO and inhibition of lipid peroxidation and inflammatory responses. Brain research. vol 1596. 2015-08-24. PMID:25463026. |
in conclusion, pre-cih telmisartan administration attenuated cih-induced hippocampal apoptosis partly by regulating nos activity, inhibiting excessive no generation, and reducing lipid peroxidation and inflammatory responses. |
2015-08-24 |
2023-08-13 |
rat |
| Jong Seok Lee, Young Rae Kim, In Gyu Song, Suk-Jin Ha, Young Eon Kim, Nam-In Baek, Eock Kee Hon. Cyanidin-3-glucoside isolated from mulberry fruit protects pancreatic β-cells against oxidative stress-induced apoptosis. International journal of molecular medicine. vol 35. issue 2. 2015-08-21. PMID:25435295. |
our results revealed that h2o2 increased the rate of apoptosis by stimulating various pro-apoptotic processes, such as the generation of intracellular reactive oxygen species (ros), lipid peroxidation, dna fragmentation and caspase-3 activation. |
2015-08-21 |
2023-08-13 |
Not clear |
| Tobias Eisenberg, Sabrina Büttne. Lipids and cell death in yeast. FEMS yeast research. vol 14. issue 1. 2015-08-07. PMID:24119111. |
studies in yeast have shed light on various aspects of lipotoxicity, including free fatty acid toxicity, sphingolipid-modulated cell death as well as the involvement of cardiolipin and lipid peroxidation in the mitochondrial pathways of apoptosis. |
2015-08-07 |
2023-08-12 |
Not clear |
| Hanaa Mahmoud Mohamed, Manal Abdul-Hamid Mohame. Effect of different doses of nandrolone decanoate on lipid peroxidation, DNA fragmentation, sperm abnormality and histopathology of testes of male Wister rats. Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie. vol 67. issue 1. 2015-08-05. PMID:25440442. |
the present study aims of to investigate the effects of low and high doses of nandrolone decanoate (nd) on histopathology and apoptosis of the spermatogenic cells as well as lipid peroxidation, antioxidant enzyme activities, sperm abnormality and dna fragmentation. |
2015-08-05 |
2023-08-13 |
rat |
| Jitender K Bhardwaj, Priyanka Sara. Malathion-induced granulosa cell apoptosis in caprine antral follicles: an ultrastructural and flow cytometric analysis. Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada. vol 20. issue 6. 2015-08-04. PMID:25409908. |
transmission electron microscopy (tem) was employed for ultrastructural characterization, oxidative stress was evaluated using thiobarbituric acid reactive substances (tbars) assay to measure lipid peroxidation, and apoptosis was quantified via flow cytometry. |
2015-08-04 |
2023-08-13 |
Not clear |
| Jitender K Bhardwaj, Priyanka Sara. Malathion-induced granulosa cell apoptosis in caprine antral follicles: an ultrastructural and flow cytometric analysis. Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada. vol 20. issue 6. 2015-08-04. PMID:25409908. |
7.57±0.033*, 8.53±0.12*, and 12.87±0.78** at 4, 6, or 8 h, respectively, as compared with controls (6.07±0.033, p<0.01*, p<0.05**) showing a positive correlation between malathion-induced lipid peroxidation and percentage of granulosa cell apoptosis (r=1; p<0.01). |
2015-08-04 |
2023-08-13 |
Not clear |
| S Goswami, C Halda. Melatonin improves ultraviolet B-induced oxidative damage and inflammatory conditions in cutaneous tissue of a diurnal Indian palm squirrel Funambulus pennanti. The British journal of dermatology. vol 171. issue 5. 2015-07-20. PMID:24863410. |
solar radiation, of which ultraviolet (uv) rays are a principle component, increases the free radical load, and the accumulation of reactive oxygen species (ros) causes lipid peroxidation, dna damage and apoptosis, and is also associated with inflammatory responses recruiting molecules [nuclear factor (nf)-κb, interleukin (il)-6] that can potentially further aggravate the damaged milieu of the cells. |
2015-07-20 |
2023-08-13 |
Not clear |
| Parvaneh Naserzadeh, Mir-Jamal Hosseini, Baharak Mohamadzadeh Asl, Jalal Pourahma. Toxicity Mechanisms of Cigarette Smoke on Mouse Fetus Mitochondria. Iranian journal of pharmaceutical research : IJPR. vol 14. issue Suppl. 2015-07-18. PMID:26185515. |
our results suggest that cse-induced embryo toxicity is the result of disruptive effect on mitochondrial respiratory chain that leads to ros formation, lipid peroxidation, mitochondrial mmp (mitochondrial membrane potential) decline and decrease of atp level which starts apoptosis signaling. |
2015-07-18 |
2023-08-13 |
mouse |
| Jing Zhao, Shouzhu Xu, Fan Song, Lun Nian, Xuanxuan Zhou, Siwang Wan. 2,3,5,4'-tetrahydroxystilbene-2-O-β-D-glucoside protects human umbilical vein endothelial cells against lysophosphatidylcholine-induced apoptosis by upregulating superoxide dismutase and glutathione peroxidase. IUBMB life. vol 66. issue 10. 2015-07-09. PMID:25382724. |
our data indicate that tsg inhibits apoptosis of huvecs mediated by lpc through blocking the mitochondrial apoptotic pathway and suggest that the mechanisms underlying the protective effects of tsg are related to the activation of sod and glutathione peroxidase, the clearance of intracellular ros, and reduction of lipid peroxidation. |
2015-07-09 |
2023-08-13 |
human |
| Jianwu Yu, Jing Wei, Ling Ji, Xutao Hon. Exploration on mechanism of a new type of melatonin receptor agonist Neu-p11 in hypoxia-reoxygenation injury of myocardial cells. Cell biochemistry and biophysics. vol 70. issue 2. 2015-07-02. PMID:24840226. |
it inhibits cell apoptosis and improves the morphology and rhythm of myocardial cells; it alleviates injury of cell membrane by reducing its permeability, which can stabilize myocardial cell membrane; it also alleviates lipid peroxidation and protects mitochondria from myocardial ischemia/reperfusion injury. |
2015-07-02 |
2023-08-13 |
Not clear |
| Dan Li, Elizabeth M Elli. Aldo-keto reductase 7A5 (AKR7A5) attenuates oxidative stress and reactive aldehyde toxicity in V79-4 cells. Toxicology in vitro : an international journal published in association with BIBRA. vol 28. issue 4. 2015-06-29. PMID:24590062. |
in previous studies, we have shown that akr7a5 enzyme is catalytically active towards aldehydes arising from lipid peroxidation (lpo) and that it can significantly protect against 4-hydroxynonenal-induced apoptosis, suggesting a protective role against the consequences of oxidative stress. |
2015-06-29 |
2023-08-12 |
Not clear |
| Gang Liu, Zifa Li, Jinqiu Wang, Hong Wang, Zhenyong Wang, Lin Wan. Puerarin protects against lead-induced cytotoxicity in cultured primary rat proximal tubular cells. Human & experimental toxicology. vol 33. issue 10. 2015-06-22. PMID:24505050. |
however, simultaneous supplementation with pu (50 and 100 µm) protected rpt cells from pb-induced cytotoxicity through inhibiting apoptosis, attenuating lipid peroxidation, renewing mitochondrial function, and elevating the intracellular antioxidants (nonenzymatic and enzymic) levels. |
2015-06-22 |
2023-08-12 |
rat |
| Qiongmei Guo, Xuefang Du, Yanli Zhao, Dong Zhang, Lihui Yue, Zhenxian Wan. Ischemic postconditioning prevents renal ischemia reperfusion injury through the induction of heat shock proteins in rats. Molecular medicine reports. vol 10. issue 6. 2015-06-19. PMID:25322861. |
ir also increased lipid peroxidation, as indicated by elevated malondialdehyde content, reduced superoxide dismutase activity and increased renal apoptosis. |
2015-06-19 |
2023-08-13 |
rat |