| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M A Shupik, A F Vanin, A V Alessenk. Interaction of the nitric oxide signaling system with the sphingomyelin cycle and peroxidation on transmission of toxic signal of tumor necrosis factor-α in ischemia-reperfusion. Biochemistry. Biokhimiia. vol 76. issue 11. 2012-03-15. PMID:22117546. |
the role of a proinflammatory cytokine tnf-α in apoptosis and ischemia-reperfusion and mechanisms of its cytotoxic action, which involve nitric oxide, the sphingomyelin cycle, and lipid peroxidation are discussed. |
2012-03-15 |
2023-08-12 |
Not clear |
| Masanori Horie, Haruhisa Kato, Shigehisa Endoh, Katsuhide Fujita, Keiko Nishio, Lilian Kaede Komaba, Hiroko Fukui, Ayako Nakamura, Arisa Miyauchi, Tetsuya Nakazato, Shinichi Kinugasa, Yasukazu Yoshida, Yoshihisa Hagihara, Yasuo Morimoto, Hitoshi Iwahash. Evaluation of cellular influences of platinum nanoparticles by stable medium dispersion. Metallomics : integrated biometal science. vol 3. issue 11. 2012-02-29. PMID:21804981. |
cell viability (mtt assay), cell proliferation (clonogenic assay), apoptosis induction (caspase-3 activity), intracellular ros level (dcfh assay), and lipid peroxidation level (dppp assay) were measured as markers of cellular influences. |
2012-02-29 |
2023-08-12 |
Not clear |
| Hirofumi Matsui, Yumiko Nagano, Osamu Shimokawa, Tsuyoshi Kaneko, Kanho Rai, Jumpei Udo, Aki Hirayama, Yukio Nakamura, Hiroko P Indo, Hideyuki J Majima, Ichinosuke Hyod. Gastric acid induces mitochondrial superoxide production and lipid peroxidation in gastric epithelial cells. Journal of gastroenterology. vol 46. issue 10. 2012-02-22. PMID:21789481. |
we hypothesized that gastric acid may disrupt mitochondrial transmembrane potential and induce the production of superoxide in mitochondria, which subsequently may induce lipid peroxidation and apoptosis in gastric mucosal cells. |
2012-02-22 |
2023-08-12 |
Not clear |
| Menaka C Thounaojam, Ravirajsinh N Jadeja, Mayur Valodkar, Padamanabhi S Nagar, Ranjitsinh V Devkar, Sonal Thakor. Oxidative stress induced apoptosis of human lung carcinoma (A549) cells by a novel copper nanorod formulation. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 49. issue 11. 2012-02-13. PMID:21820027. |
also, reduced glutathione (gsh), lipid peroxidation (lpo), cellular oxidative stress (rhodamine 123 florescence) and apoptosis (annexin v fitc/propidium iodide staining) were also investigated in control and treated cells. |
2012-02-13 |
2023-08-12 |
human |
| Indika B Gawarammana, Nicholas A Buckle. Medical management of paraquat ingestion. British journal of clinical pharmacology. vol 72. issue 5. 2012-02-09. PMID:21615775. |
paraquat generates reactive oxygen species which cause cellular damage via lipid peroxidation, activation of nf-κb, mitochondrial damage and apoptosis in many organs. |
2012-02-09 |
2023-08-12 |
human |
| Qin-li Zhang, Fang Wang, Ying-tao Shi, Lin-ping Wang, Ling Zhang, Hong-mei Zhang, Jing Wang, Qiu-ying Li, Qiao Ni. [Lipid peroxidation injury and endoplasmic reticulum stress in Al-induced apoptosis]. Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases. vol 26. issue 3. 2012-01-23. PMID:18761791. |
[lipid peroxidation injury and endoplasmic reticulum stress in al-induced apoptosis]. |
2012-01-23 |
2023-08-12 |
Not clear |
| Qin-li Zhang, Fang Wang, Ying-tao Shi, Lin-ping Wang, Ling Zhang, Hong-mei Zhang, Jing Wang, Qiu-ying Li, Qiao Ni. [Lipid peroxidation injury and endoplasmic reticulum stress in Al-induced apoptosis]. Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases. vol 26. issue 3. 2012-01-23. PMID:18761791. |
to study the role of lipid peroxidation injury and endoplasmic reticulum stress in al-induced apoptosis. |
2012-01-23 |
2023-08-12 |
Not clear |
| Shumin Zhang, Xuexi Tang, Jingwei Tian, Chunmei Li, Guanbo Zhang, Wanglin Jiang, Zunting Zhan. Cardioprotective effect of sulphonated formononetin on acute myocardial infarction in rats. Basic & clinical pharmacology & toxicology. vol 108. issue 6. 2012-01-09. PMID:21232020. |
a possible mechanism for the protective effect is the elevated expression of endogenous antioxidant defence enzymes degraded lipid peroxidation products and improved energy metholism of cardiac mitochondrial, thus attenuating cardiocyte apoptosis. |
2012-01-09 |
2023-08-12 |
rat |
| Marta Kubera, Ewa Obuchowicz, Lisa Goehler, Joanna Brzeszcz, Michael Mae. In animal models, psychosocial stress-induced (neuro)inflammation, apoptosis and reduced neurogenesis are associated to the onset of depression. Progress in neuro-psychopharmacology & biological psychiatry. vol 35. issue 3. 2012-01-06. PMID:20828592. |
external stress-induced depression-like behaviors are associated with a) increased interleukin-(il)1β, tumor necrosis factor-α, il-6, nuclear factor κb, cyclooxygenase-2, expression of toll-like receptors and lipid peroxidation; b) antineurogenic effects and reduced brain-derived neurotrophic factor (bdnf) levels; and c) apoptosis with reduced levels of bcl-2 and bag1 (bcl-2 associated athanogene 1), and increased levels of caspase-3. |
2012-01-06 |
2023-08-12 |
Not clear |
| Mustafa Sönmez, Gaffari Türk, Ali Osman Çeribaşı, Fatih Sakin, Ahmet Ateşşahi. Attenuating effect of lycopene and ellagic acid on 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced spermiotoxicity and testicular apoptosis. Drug and chemical toxicology. vol 34. issue 4. 2012-01-05. PMID:21714773. |
sperm motility, concentration, and abnormal sperm rate in epididymal tissue, testicular tissue lipid peroxidation (lpo), antioxidant enzyme activity, histopathological changes, and apoptosis (i.e., bax and bcl-2 proteins) were determined. |
2012-01-05 |
2023-08-12 |
rat |
| Mustafa Sönmez, Gaffari Türk, Ali Osman Çeribaşı, Fatih Sakin, Ahmet Ateşşahi. Attenuating effect of lycopene and ellagic acid on 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced spermiotoxicity and testicular apoptosis. Drug and chemical toxicology. vol 34. issue 4. 2012-01-05. PMID:21714773. |
tcdd-induced lipid peroxidation leads to functional and structural damages, as well as apoptosis, in spermatogenic cells of rats. |
2012-01-05 |
2023-08-12 |
rat |
| Ping-Yuan Lin, Hung-Jen Liu, Ching-Dong Chang, Chi-I Chang, Jue-Liang Hsu, Ming-Huei Liao, Jeng-Woei Lee, Wen-Ling Shi. Avian reovirus S1133-induced DNA damage signaling and subsequent apoptosis in cultured cells and in chickens. Archives of virology. vol 156. issue 11. 2011-12-29. PMID:21779911. |
ros and lipid peroxidation levels were increased, and arv s1133 and σc caused apoptosis mediated by dna damage signaling. |
2011-12-29 |
2023-08-12 |
Not clear |
| Erkan Yurtcu, Ozlem Darcansoy Iseri, Feride I Sahi. Effects of ascorbic acid and β-carotene on HepG2 human hepatocellular carcinoma cell line. Molecular biology reports. vol 38. issue 7. 2011-12-27. PMID:21116852. |
ascorbic acid and β-carotene were applied to cells as plasma peak concentrations (70 and 8 μm, respectively) and their half concentrations (35 and 4 μm, respectively) for 24 and 48 h. genotoxic and cytotoxic effects of ascorbic acid and β-carotene were evaluated by alkali single cell gel electrophoresis (scge), acridine orange/ethidium bromide staining patterns of cells (apoptosis and necrosis) and lipid peroxidation (thiobarbituric acid reactive substances, tbars). |
2011-12-27 |
2023-08-12 |
human |
| Stefania Zampieri, Synthia H Mellon, Terry D Butters, Marco Nevyjel, Douglas F Covey, Bruno Bembi, Andrea Dardi. Oxidative stress in NPC1 deficient cells: protective effect of allopregnanolone. Journal of cellular and molecular medicine. vol 13. issue 9B. 2011-12-23. PMID:18774957. |
allo treatment of fibroblasts from npc patients or npc1 knockdown cells reduced the levels of ros and lipid peroxidation and prevented peroxide-induced apoptosis and nf-kb activation. |
2011-12-23 |
2023-08-12 |
mouse |
| El-Sayed M El-Sayed, Abdel-Aziz H Abdel-Aziz, Samira Saleh, Ahmed S Saa. The chemopreventive effect of dimethylthiourea against carmustine-induced myelotoxicity in rats. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 49. issue 9. 2011-12-07. PMID:21620922. |
the possible chemopreventive role of dimethylthiourea (dmtu) against carmustine (1,3-bis(2-chloroethyl)-1-nitrosourea, bcnu)-induced myelotoxicity was assessed through evaluation of apoptosis, lipid peroxidation, glutathione (gsh) content and some antioxidant enzymes activities in bone marrow cells of rats. |
2011-12-07 |
2023-08-12 |
rat |
| Nurdan Bedirli, Nalan Akyürek, Omer Kurtipek, Mustafa Kavutcu, Seyfi Kartal, Asli Cavunt Bayrakta. Thoracic epidural bupivacaine attenuates inflammatory response, intestinal lipid peroxidation, oxidative injury, and mucosal apoptosis induced by mesenteric ischemia/reperfusion. Anesthesia and analgesia. vol 113. issue 5. 2011-12-07. PMID:21865496. |
thoracic epidural bupivacaine attenuates inflammatory response, intestinal lipid peroxidation, oxidative injury, and mucosal apoptosis induced by mesenteric ischemia/reperfusion. |
2011-12-07 |
2023-08-12 |
rat |
| Lijuan Wang, Yingxian Sun, Michio Asahi, Kinya Ots. Acrolein, an environmental toxin, induces cardiomyocyte apoptosis via elevated intracellular calcium and free radicals. Cell biochemistry and biophysics. vol 61. issue 1. 2011-11-29. PMID:21350837. |
acrolein, an unsaturated aldehyde, is an environmental toxin known to inhibit mitochondrial electron transport chain in brain and induce lipid peroxidation and apoptosis. |
2011-11-29 |
2023-08-12 |
mouse |
| Wei-Wei Xing, Min-Ji Zou, Shen Liu, Tao Xu, Jia-Xi Wang, Dong-Gang X. Interleukin-22 protects against acute alcohol-induced hepatotoxicity in mice. Bioscience, biotechnology, and biochemistry. vol 75. issue 7. 2011-11-28. PMID:21737938. |
the results indicated that acute alcohol administration caused prominent hepatic microvesicular steatosis and an elevation of serum transaminase activities, induced a significant decrease in hepatic glutathione in conjunction with enhanced lipid peroxidation, and increased hepatocyte apoptosis as well as hepatic tnf-alpha production. |
2011-11-28 |
2023-08-12 |
mouse |
| Shiekh Tanveer Ahmad, Wani Arjumand, Amlesh Seth, Sana Nafees, Summya Rashid, Nemat Ali, Sarwat Sultan. Preclinical renal cancer chemopreventive efficacy of geraniol by modulation of multiple molecular pathways. Toxicology. vol 290. issue 1. 2011-11-21. PMID:21907755. |
the chemopreventive efficacy of goh was studied in terms of xenobiotic metabolizing enzyme activities, lpo, redox status, serum toxicity markers and the expression of putative nephrotoxicity biomarker kim-1, tumor suppressor gene p53, inflammation, cell proliferation and apoptosis related genes in the kidney tissue. |
2011-11-21 |
2023-08-12 |
rat |
| Paola Barraja, Patrizia Diana, Alessandra Montalbano, Anna Carbone, Giampietro Viola, Giuseppe Basso, Alessia Salvador, Daniela Vedaldi, Francesco Dall'Acqua, Girolamo Cirrincion. Pyrrolo[3,4-h]quinolinones a new class of photochemotherapeutic agents. Bioorganic & medicinal chemistry. vol 19. issue 7. 2011-10-24. PMID:21397509. |
the induced cellular photocytotoxicity was related to apoptosis with the involvement of mitochondria and lysosomes, alteration of cell cycle profile and membrane lipid peroxidation. |
2011-10-24 |
2023-08-12 |
Not clear |