| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Karthikeyan Chandrasekaran, Kavitha Swaminathan, Suvro Chatterjee, Aparajita De. Apoptosis in HepG2 cells exposed to high glucose. Toxicology in vitro : an international journal published in association with BIBRA. vol 24. issue 2. 2010-06-02. PMID:19892008. |
glucose induced apoptosis in hepg2 cells was a consequence of increased oxidative stress as evidenced by the increased reactive oxygen species (ros) level, lipid peroxidation, protein carbonyl and 3-nitrotyrosine adduct formation. |
2010-06-02 |
2023-08-12 |
human |
| Olivia Vázquez-Martínez, Angélica Loranca, Lourdes Palma-Tirado, Sabina Wischin-Fuentes, Mónica Villalobos-Leal, Anaid Antaramián, Juan Riesgo-Escovar, Rolando Hernández-Muñoz, Mauricio Díaz-Muño. Time course of retinal degeneration associated with the absence of 1, 4, 5-inositol trisphosphate receptor in Drosophila melanogaster. Experimental biology and medicine (Maywood, N.J.). vol 235. issue 3. 2010-05-20. PMID:20404055. |
episodes of enhanced lipid peroxidation and apoptosis were also observed in the pigmented ommatidia of the mosaic eyes. |
2010-05-20 |
2023-08-12 |
drosophila_melanogaster |
| Zekiye Sultan Altun, Dilek Güneş, Safiye Aktaş, Zübeyde Erbayraktar, Zübeyde Erbayrktar, Nur Olgu. Protective effects of acetyl-L-carnitine on cisplatin cytotoxicity and oxidative stress in neuroblastoma. Neurochemical research. vol 35. issue 3. 2010-04-30. PMID:19851866. |
prophylactic 10 and 50 micromol of alc concentrations were decreased cisplatin induced lipid peroxidation compared to controls that normally exhibited apoptosis especially in sh-sy5y cells. |
2010-04-30 |
2023-08-12 |
human |
| María Elvira López-Oliva, Angel Agis-Torres, Isabel Goñi, Emilia Muñoz-Martíne. Grape antioxidant dietary fibre reduced apoptosis and induced a pro-reducing shift in the glutathione redox state of the rat proximal colonic mucosa. The British journal of nutrition. vol 103. issue 8. 2010-04-30. PMID:19930767. |
the gsh:gssg ratio, the redox state of the gssg/2gsh couple (ehc), the mitochondrial and/or cytosolic antioxidant enzyme activities (superoxide dismutase (sod), catalase (cat) and glutathione peroxidase (gpx)), lipid peroxidation (lpo) and apoptosis were evaluated. |
2010-04-30 |
2023-08-12 |
rat |
| Faruk Abas, Tulin Alkan, Bulent Goren, Ozgur Taskapilioglu, Emre Sarandol, Sahsene Toluna. Neuroprotective effects of postconditioning on lipid peroxidation and apoptosis after focal cerebral ischemia/reperfusion injury in rats. Turkish neurosurgery. vol 20. issue 1. 2010-04-30. PMID:20066614. |
neuroprotective effects of postconditioning on lipid peroxidation and apoptosis after focal cerebral ischemia/reperfusion injury in rats. |
2010-04-30 |
2023-08-12 |
rat |
| Daniel E Francés, María T Ronco, Juan A Monti, Paola I Ingaramo, Gerardo B Pisani, Juan P Parody, José M Pellegrino, Paloma Martín Sanz, María C Carrillo, Cristina E Carnoval. Hyperglycemia induces apoptosis in rat liver through the increase of hydroxyl radical: new insights into the insulin effect. The Journal of endocrinology. vol 205. issue 2. 2010-04-30. PMID:20164374. |
interestingly, the treatment of diabetic rats with desferoxamine or tempol (antioxidants/hydroxyl radical scavengers) significantly attenuated the increase in both hydroxyl radical production and in lpo produced by hyperglycemia, preventing apoptosis by reduction of mitochondrial bax and cytosolic cytochrome c levels. |
2010-04-30 |
2023-08-12 |
rat |
| Chang-Yu Chen, Tsu-Kung Lin, Yi-Chuang Chang, Yi-Fen Wang, Huey-Wen Shyu, Kuan-Hua Lin, Miao-Chen Cho. Nickel(II)-induced oxidative stress, apoptosis, G2/M arrest, and genotoxicity in normal rat kidney cells. Journal of toxicology and environmental health. Part A. vol 73. issue 8. 2010-04-28. PMID:20391133. |
in order to elucidate the effects of nickel (ni) on oxidative stress, apoptosis, and genotoxicity in renal cells, the levels of intracellular oxidants, lipid peroxidation, apoptotic proteins, and dna damage were measured in normal rat kidney (nrk) cells after nickel chloride (nicl(2)) treatment. |
2010-04-28 |
2023-08-12 |
rat |
| Rajendra Sharma, Abha Sharma, Pankaj Chaudhary, Virginia Pearce, Rit Vatsyayan, Shivendra V Singh, Sanjay Awasthi, Yogesh C Awasth. Role of lipid peroxidation in cellular responses to D,L-sulforaphane, a promising cancer chemopreventive agent. Biochemistry. vol 49. issue 14. 2010-04-22. PMID:20205397. |
because 4-hydroxynonenal (4-hne), a product of lipid peroxidation (lpo), the formation of which is regulated by hgsta1-1, assumes a pivotal role in oxidative stress-induced signal transduction, we investigated its contribution in growth arrest and apoptosis induction by sfn using hl60 and k562 human leukemic cell lines as a model. |
2010-04-22 |
2023-08-12 |
mouse |
| Yun Jung Lee, Kwang Sik Suh, Moon Chan Choi, Suk Chon, Seungjoon Oh, Jeong-Taek Woo, Sung-Woon Kim, Jin-Woo Kim, Young Seol Ki. Kaempferol protects HIT-T15 pancreatic beta cells from 2-deoxy-D-ribose-induced oxidative damage. Phytotherapy research : PTR. vol 24. issue 3. 2010-04-13. PMID:19827031. |
cell survivals, amounts of reactive oxygen species (ros) generated, apoptosis, and lipid peroxidation were measured. |
2010-04-13 |
2023-08-12 |
Not clear |
| Yun Jung Lee, Kwang Sik Suh, Moon Chan Choi, Suk Chon, Seungjoon Oh, Jeong-Taek Woo, Sung-Woon Kim, Jin-Woo Kim, Young Seol Ki. Kaempferol protects HIT-T15 pancreatic beta cells from 2-deoxy-D-ribose-induced oxidative damage. Phytotherapy research : PTR. vol 24. issue 3. 2010-04-13. PMID:19827031. |
drib was found to dose-dependently reduce cell survival and to markedly increase intracellular ros levels, apoptosis, and lipid peroxidation. |
2010-04-13 |
2023-08-12 |
Not clear |
| Yun Jung Lee, Kwang Sik Suh, Moon Chan Choi, Suk Chon, Seungjoon Oh, Jeong-Taek Woo, Sung-Woon Kim, Jin-Woo Kim, Young Seol Ki. Kaempferol protects HIT-T15 pancreatic beta cells from 2-deoxy-D-ribose-induced oxidative damage. Phytotherapy research : PTR. vol 24. issue 3. 2010-04-13. PMID:19827031. |
however, kaempferol (10 microm) suppressed drib (20 mm) induced intracellular ros, apoptosis, and lipid peroxidation. |
2010-04-13 |
2023-08-12 |
Not clear |
| Yue-Hua Wang, Guan-Hua D. Ginsenoside Rg1 inhibits beta-secretase activity in vitro and protects against Abeta-induced cytotoxicity in PC12 cells. Journal of Asian natural products research. vol 11. issue 7. 2010-04-12. PMID:20183297. |
the results showed that 1 could inhibit beta-secretase activity in vitro and also protect the pc12 cells against injuries caused by exposure of pc12 cells to 50 microm abeta(25-35) for 48 h. the cell death, ldh release, no release, ros production, lipid peroxidation, intracellular calcium elevation, and apoptosis are associated events induced by abeta that can be rescued by 1 in pc12 cells. |
2010-04-12 |
2023-08-12 |
Not clear |
| Dan Sun, Sujuan Zhang, Yongfeng Wei, Lingfang Yi. Antioxidant activity of mangostin in cell-free system and its effect on K562 leukemia cell line in photodynamic therapy. Acta biochimica et biophysica Sinica. vol 41. issue 12. 2010-03-29. PMID:20011978. |
mag inhibits cell proliferation and enhances cell apoptosis, lipid peroxidation, and dna damage in ala-pdt on k562 cells. |
2010-03-29 |
2023-08-12 |
Not clear |
| Dan Sun, Sujuan Zhang, Yongfeng Wei, Lingfang Yi. Antioxidant activity of mangostin in cell-free system and its effect on K562 leukemia cell line in photodynamic therapy. Acta biochimica et biophysica Sinica. vol 41. issue 12. 2010-03-29. PMID:20011978. |
nan3, a singlet oxygen quencher, suppresses the mag-induced cell apoptosis, lipid peroxidation, and dna damage. |
2010-03-29 |
2023-08-12 |
Not clear |
| Dongsun Park, Jeong Hee Jeon, Sang-Chul Kwon, Sunhee Shin, Ja Young Jang, Heon Sang Jeong, Do Ik Lee, Yun-Bae Kim, Seong Soo Jo. Antioxidative activities of white rose flower extract and pharmaceutical advantages of its hexane fraction via free radical scavenging effects. Biochemistry and cell biology = Biochimie et biologie cellulaire. vol 87. issue 6. 2010-03-04. PMID:19935880. |
in addition, more advanced antioxidant assays were conducted, including lipid peroxidation, hydroxyl radical-mediated oxidation, dna fragmentation, apoptosis, and cell growth. |
2010-03-04 |
2023-08-12 |
Not clear |
| Bulent Erol, Murat Bozlu, Volkan Hanci, Husnu Tokgoz, Sibel Bektas, Gorkem Munga. Coenzyme Q10 treatment reduces lipid peroxidation, inducible and endothelial nitric oxide synthases, and germ cell-specific apoptosis in a rat model of testicular ischemia/reperfusion injury. Fertility and sterility. vol 93. issue 1. 2010-02-22. PMID:19683231. |
coenzyme q10 treatment reduces lipid peroxidation, inducible and endothelial nitric oxide synthases, and germ cell-specific apoptosis in a rat model of testicular ischemia/reperfusion injury. |
2010-02-22 |
2023-08-12 |
rat |
| Bulent Erol, Murat Bozlu, Volkan Hanci, Husnu Tokgoz, Sibel Bektas, Gorkem Munga. Coenzyme Q10 treatment reduces lipid peroxidation, inducible and endothelial nitric oxide synthases, and germ cell-specific apoptosis in a rat model of testicular ischemia/reperfusion injury. Fertility and sterility. vol 93. issue 1. 2010-02-22. PMID:19683231. |
the results of this study show that coq(10) administration before the reperfusion period of testicular torsion provides a significant decrease in testicular lipid peroxidation products and expressions of inducible nitric oxide synthase, endothelial nitric oxide synthase, and germ cell-specific apoptosis. |
2010-02-22 |
2023-08-12 |
rat |
| Takashi Amo, Noriaki Kawanishi, Masataka Uchida, Hirofumi Fujita, Eri Oyanagi, Toshihiko Utsumi, Tetsuya Ogino, Keiji Inoue, Taro Shuin, Kozo Utsumi, Junzo Sasak. Mechanism of cell death by 5-aminolevulinic acid-based photodynamic action and its enhancement by ferrochelatase inhibitors in human histiocytic lymphoma cell line U937. Cell biochemistry and function. vol 27. issue 8. 2010-02-22. PMID:19735078. |
pda induced apoptosis characterized by lipid peroxidation, increase in bak and bax/bcl-xl, decrease in bid, membrane depolarization, cytochrome c release, caspase-3 activation, phosphatidylserine (ps) externalization. |
2010-02-22 |
2023-08-12 |
human |
| Irene Paterniti, Tiziana Genovese, Emanuela Mazzon, Concetta Crisafulli, Rosanna Di Paola, Maria Galuppo, Placido Bramanti, Salvatore Cuzzocre. Liver X receptor agonist treatment regulates inflammatory response after spinal cord trauma. Journal of neurochemistry. vol 112. issue 3. 2010-02-16. PMID:19891733. |
treatment with t0901317, 1 and 6 h after the sci, significantly decreased (i) the degree of spinal cord inflammation and tissue injury (histological score); (ii) neutrophil infiltration (myeloperoxidase activity); (iii) inducible nitric oxide synthase expression; (iv) nitrotyrosine, lipid peroxidation, and poly-adp-ribose formation; (v) pro-inflammatory cytokines expression; (vi) nuclear factor-kappa b activation; and (vii) apoptosis (terminal deoxynucleotidyltransferase-mediated utp end labeling staining, fas ligand, bax, and bcl-2 expression). |
2010-02-16 |
2023-08-12 |
mouse |
| Hai-Dan Yuan, Guang-Zhu Jin, Guang-Chun Pia. Protective Effects of the Supernatant of Ethanol Eluate from Artemisia sacrorum Ledeb. against Acetaminophen-Induced Liver Injury in Mice [corrected]. Biological & pharmaceutical bulletin. vol 32. issue 10. 2010-01-28. PMID:19801828. |
all these results suggest that the protective effects of ase against apap-induced liver injury may involve mechanisms associated with its inhibitive effects of lipid peroxidation and the down-regulation of tnf-alpha mediated apoptosis. |
2010-01-28 |
2023-08-12 |
mouse |