Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Babilonia Barqasho, Piotr Nowak, Samir Abdurahman, Lillian Walther-Jallow, Anders Sönnerbor. Implications of the release of high-mobility group box 1 protein from dying cells during human immunodeficiency virus type 1 infection in vitro. The Journal of general virology. vol 91. issue Pt 7. 2010-07-09. PMID:20200191. |
mt4 cells and primary cd4(+) t cells were infected with hiv-1 isolates, and hmgb1 release was monitored in relation to cytopathic effects (cpe) and apoptosis. |
2010-07-09 |
2023-08-12 |
human |
Babilonia Barqasho, Piotr Nowak, Samir Abdurahman, Lillian Walther-Jallow, Anders Sönnerbor. Implications of the release of high-mobility group box 1 protein from dying cells during human immunodeficiency virus type 1 infection in vitro. The Journal of general virology. vol 91. issue Pt 7. 2010-07-09. PMID:20200191. |
both necrosis and apoptosis contributed to hmgb1 liberation during hiv-1-induced cell death and the protein could induce tumour necrosis factor-alpha release from peripheral mononuclear blood cells. |
2010-07-09 |
2023-08-12 |
human |
Yukiko Moriwaka, Yi Luo, Hitoshi Ohmori, Kiyomu Fujii, Naokuni Tatsumoto, Tomonori Sasahira, Hiroki Kuniyas. HMGB1 attenuates anti-metastatic defense of the lymph nodes in colorectal cancer. Pathobiology : journal of immunopathology, molecular and cellular biology. vol 77. issue 1. 2010-06-14. PMID:20185963. |
cancer-secreted high mobility group 1 (hmgb1) induces apoptosis of macrophages and suppresses the host anti-cancer immune system. |
2010-06-14 |
2023-08-12 |
Not clear |
Feng Liu, Yong-ming Yao, Ning Dong, Shan Xu, Zhi-yong Shen. [High mobility group box-1 protein induces apoptosis in mouse peritoneal macrophages]. Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae. vol 29. issue 4. 2010-05-19. PMID:19209790. |
to investigate the effect of high mobility group box-1 protein (hmgb1) on apoptosis of macrophages in mice. |
2010-05-19 |
2023-08-12 |
mouse |
Daolin Tang, Rui Kang, Herbert J Zeh, Michael T Lotz. High-mobility group box 1 and cancer. Biochimica et biophysica acta. vol 1799. issue 1-2. 2010-04-21. PMID:20123075. |
overexpression of hmgb1 is associated with each of the hallmarks of cancer including unlimited replicative potential, ability to develop blood vessels (angiogenesis), evasion of programmed cell death (apoptosis), self-sufficiency in growth signals, insensitivity to inhibitors of growth, inflammation, tissue invasion and metastasis. |
2010-04-21 |
2023-08-12 |
Not clear |
Yi Luo, Hitoshi Ohmori, Kiyomu Fujii, Yukiko Moriwaka, Tomonori Sasahira, Miyako Kurihara, Naokuni Tatsumoto, Takamitsu Sasaki, Yuichi Yamashita, Hiroki Kuniyas. HMGB1 attenuates anti-metastatic defence of the liver in colorectal cancer. European journal of cancer (Oxford, England : 1990). vol 46. issue 4. 2010-04-09. PMID:20018503. |
hmgb1 induced growth inhibition and apoptosis in mouse kcs in a dose-dependent manner, which was associated with the phosphorylation of c-jun n-terminal kinase (jnk). |
2010-04-09 |
2023-08-12 |
mouse |
Yi Luo, Hitoshi Ohmori, Kiyomu Fujii, Yukiko Moriwaka, Tomonori Sasahira, Miyako Kurihara, Naokuni Tatsumoto, Takamitsu Sasaki, Yuichi Yamashita, Hiroki Kuniyas. HMGB1 attenuates anti-metastatic defence of the liver in colorectal cancer. European journal of cancer (Oxford, England : 1990). vol 46. issue 4. 2010-04-09. PMID:20018503. |
jnk inhibition and knockdown of hmgb1 receptor abrogated growth inhibition and apoptosis. |
2010-04-09 |
2023-08-12 |
mouse |
Min Xie, Rui Kang, Yan Yu, Shan Zhu, Yu-Lei He, Wang-Qiong Xu, Dao-Lin Tang, Li-Zhi Ca. [Enhancive effect of HMGB1 gene silence on adriamycin-induced apoptosis in K562/A02 drug resistance leukemia cells]. Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi. vol 29. issue 8. 2010-04-08. PMID:19112920. |
[enhancive effect of hmgb1 gene silence on adriamycin-induced apoptosis in k562/a02 drug resistance leukemia cells]. |
2010-04-08 |
2023-08-12 |
Not clear |
Jae-Min Yuk, Chul-Su Yang, Dong-Min Shin, Kwang-Kyu Kim, Sang Ki Lee, Yun Jeong Song, Hye-Mi Lee, Chung-Hyun Cho, Byeong Hwa Jeon, Eun-Kyeong J. A dual regulatory role of apurinic/apyrimidinic endonuclease 1/redox factor-1 in HMGB1-induced inflammatory responses. Antioxidants & redox signaling. vol 11. issue 3. 2010-03-01. PMID:18715145. |
the activation of apoptosis signal-regulating kinase 1 was required for both the p38 and jnk activation challenge with hmgb1. |
2010-03-01 |
2023-08-12 |
human |
Cho Hee Kim, A Ra Ko, Su Yeon Lee, Hyun Min Jeon, Sun Mi Kim, Hye Gyeong Park, Song Iy Han, Ho Sung Kan. Hypoxia switches glucose depletion-induced necrosis to phosphoinositide 3-kinase/Akt-dependent apoptosis in A549 lung adenocarcinoma cells. International journal of oncology. vol 36. issue 1. 2010-02-22. PMID:19956840. |
in this study, we examined the effects of hypoxia on gd-induced necrosis and show that hypoxia prevented gd-induced mitochondrial ros production, hmgb1 release, and necrosis and switched the cell death mode to apoptosis that is dependent on caspase-3 and -9. |
2010-02-22 |
2023-08-12 |
Not clear |
Daniel J Antoine, Dominic P Williams, Anja Kipar, Rosalind E Jenkins, Sophie L Regan, Jean G Sathish, Neil R Kitteringham, B Kevin Par. High-mobility group box-1 protein and keratin-18, circulating serum proteins informative of acetaminophen-induced necrosis and apoptosis in vivo. Toxicological sciences : an official journal of the Society of Toxicology. vol 112. issue 2. 2010-01-25. PMID:19783637. |
hypoacetylated hmgb1 (necrosis indicator), caspase-cleaved k18 (apoptosis indicator), and full-length k18 (necrosis indicator) present in serum showed strong correlations with the histological time course of cell death and was more sensitive than alanine aminotransferase activity. |
2010-01-25 |
2023-08-12 |
mouse |
Julie Gauley, David S Pisetsk. The translocation of HMGB1 during cell activation and cell death. Autoimmunity. vol 42. issue 4. 2009-12-22. PMID:19811282. |
with apoptosis, hmgb1 is only released during secondary necrosis, when cell permeability barriers break down. |
2009-12-22 |
2023-08-12 |
Not clear |
Julie Gauley, David S Pisetsk. The translocation of HMGB1 during cell activation and cell death. Autoimmunity. vol 42. issue 4. 2009-12-22. PMID:19811282. |
since agents that stimulate mphi can also induce apoptosis, hmgb1 release following tlr stimulation may also reflect a contribution from dead cells, suggesting a common mechanism for protein release in activation and death. |
2009-12-22 |
2023-08-12 |
Not clear |
Vilma Urbonaviciute, Silke Meister, Barbara G Fürnrohr, Benjamin Frey, Eva Gückel, Georg Schett, Martin Herrmann, Reinhard E Vol. Oxidation of the alarmin high-mobility group box 1 protein (HMGB1) during apoptosis. Autoimmunity. vol 42. issue 4. 2009-12-22. PMID:19811284. |
oxidation of the alarmin high-mobility group box 1 protein (hmgb1) during apoptosis. |
2009-12-22 |
2023-08-12 |
Not clear |
Xiao-Mei Zhu, Yong-Ming Yao, Hua-Ping Liang, Feng Liu, Ning Dong, Yan Yu, Zhi-Yong Shen. Effect of high mobility group box-1 protein on apoptosis of peritoneal macrophages. Archives of biochemistry and biophysics. vol 492. issue 1-2. 2009-12-17. PMID:19800306. |
the present study was performed to clarify the effects of high mobility group box-1 protein (hmgb1), a recently described late-acting pro-inflammatory cytokine, on apoptosis of macrophages. |
2009-12-17 |
2023-08-12 |
mouse |
Xiao-Mei Zhu, Yong-Ming Yao, Hua-Ping Liang, Feng Liu, Ning Dong, Yan Yu, Zhi-Yong Shen. Effect of high mobility group box-1 protein on apoptosis of peritoneal macrophages. Archives of biochemistry and biophysics. vol 492. issue 1-2. 2009-12-17. PMID:19800306. |
treatment with hmgb1 (0.01, 0.1, 1, 10 microg/ml for 24 h, or 10 microg/ml for 6, 12, 24, 48 h) resulted in a dose- and time-dependent induction of apoptosis in mice macrophages, peaked at 24 h after 10 microg/ml hmgb1 stimulation. |
2009-12-17 |
2023-08-12 |
mouse |
Xiao-Mei Zhu, Yong-Ming Yao, Hua-Ping Liang, Feng Liu, Ning Dong, Yan Yu, Zhi-Yong Shen. Effect of high mobility group box-1 protein on apoptosis of peritoneal macrophages. Archives of biochemistry and biophysics. vol 492. issue 1-2. 2009-12-17. PMID:19800306. |
blockage of rage and caspase-3 activation could significantly reduce apoptosis of macrophages induced by hmgb1. |
2009-12-17 |
2023-08-12 |
mouse |
Xiao-Mei Zhu, Yong-Ming Yao, Hua-Ping Liang, Feng Liu, Ning Dong, Yan Yu, Zhi-Yong Shen. Effect of high mobility group box-1 protein on apoptosis of peritoneal macrophages. Archives of biochemistry and biophysics. vol 492. issue 1-2. 2009-12-17. PMID:19800306. |
rage, together with caspase-3 activation and inhibition of nf-kappab signaling pathways, might be involved in the pathogenesis of macrophage apoptosis induced by hmgb1. |
2009-12-17 |
2023-08-12 |
mouse |
Lisa Trisciuoglio, Marco Emilio Bianch. Several nuclear events during apoptosis depend on caspase-3 activation but do not constitute a common pathway. PloS one. vol 4. issue 7. 2009-11-10. PMID:19641621. |
a number of nuclear events occur during apoptosis, including dna laddering, nuclear lamina breakdown, phosphorylation of histones h2b and histone h2ax, and the tight binding to chromatin of hmgb1 and cad, the nuclease responsible for dna laddering. |
2009-11-10 |
2023-08-12 |
human |
Ramin Lotfi, Gloria Isabelle Herzog, Richard Anthony DeMarco, Donna Beer-Stolz, James Joseph Lee, Anna Rubartelli, Hubert Schrezenmeier, Michael Thomas Lotz. Eosinophils oxidize damage-associated molecular pattern molecules derived from stressed cells. Journal of immunology (Baltimore, Md. : 1950). vol 183. issue 8. 2009-11-10. PMID:19794066. |
high mobility group box 1 (hmgb1), a prototypic damage-associated molecular pattern molecule, released following necrosis but not apoptosis, induced a similar effect on eos. |
2009-11-10 |
2023-08-12 |
Not clear |