| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Weiwen Jiang, Charles W Bell, David S Pisetsk. The relationship between apoptosis and high-mobility group protein 1 release from murine macrophages stimulated with lipopolysaccharide or polyinosinic-polycytidylic acid. Journal of immunology (Baltimore, Md. : 1950). vol 178. issue 10. 2007-06-13. PMID:17475879. |
therefore, because of evidence that apoptotic as well as necrotic cells can contribute to hmgb1-mediated events in sepsis, we have investigated the relationship between apoptosis and hmgb1 release in macrophages and other cells. |
2007-06-13 |
2023-08-12 |
human |
| Weiwen Jiang, Charles W Bell, David S Pisetsk. The relationship between apoptosis and high-mobility group protein 1 release from murine macrophages stimulated with lipopolysaccharide or polyinosinic-polycytidylic acid. Journal of immunology (Baltimore, Md. : 1950). vol 178. issue 10. 2007-06-13. PMID:17475879. |
with both lps and poly(i:c), the extent of hmgb1 release correlated with the occurrence of apoptosis as measured by caspase 3 activation, lactate dehydrogenase release, and tunel staining. |
2007-06-13 |
2023-08-12 |
human |
| Weiwen Jiang, Charles W Bell, David S Pisetsk. The relationship between apoptosis and high-mobility group protein 1 release from murine macrophages stimulated with lipopolysaccharide or polyinosinic-polycytidylic acid. Journal of immunology (Baltimore, Md. : 1950). vol 178. issue 10. 2007-06-13. PMID:17475879. |
for jurkat cells, poly(i:c) and no donors induced apoptosis as well as hmgb1 release. |
2007-06-13 |
2023-08-12 |
human |
| Weiwen Jiang, Charles W Bell, David S Pisetsk. The relationship between apoptosis and high-mobility group protein 1 release from murine macrophages stimulated with lipopolysaccharide or polyinosinic-polycytidylic acid. Journal of immunology (Baltimore, Md. : 1950). vol 178. issue 10. 2007-06-13. PMID:17475879. |
together, these results indicate that hmgb1 release from macrophages is correlated with the occurrence of apoptosis and suggest that these processes reflect common mechanisms and can occur concomitantly. |
2007-06-13 |
2023-08-12 |
human |
| Charles W Bell, Weiwen Jiang, Charles F Reich, David S Pisetsk. The extracellular release of HMGB1 during apoptotic cell death. American journal of physiology. Cell physiology. vol 291. issue 6. 2007-02-15. PMID:16855214. |
the movement of hmgb1 into the extracellular space has been demonstrated for macrophages stimulated with lps as well as cells undergoing necrosis but not apoptosis. |
2007-02-15 |
2023-08-12 |
Not clear |
| Charles W Bell, Weiwen Jiang, Charles F Reich, David S Pisetsk. The extracellular release of HMGB1 during apoptotic cell death. American journal of physiology. Cell physiology. vol 291. issue 6. 2007-02-15. PMID:16855214. |
since apoptotic cells can release some nuclear molecules such as dna to which hmgb1 can bind, we therefore investigated whether hmgb1 release can occur during apoptosis as well as necrosis. |
2007-02-15 |
2023-08-12 |
Not clear |
| Charles W Bell, Weiwen Jiang, Charles F Reich, David S Pisetsk. The extracellular release of HMGB1 during apoptotic cell death. American journal of physiology. Cell physiology. vol 291. issue 6. 2007-02-15. PMID:16855214. |
for this purpose, jurkat cells were treated with chemical inducers of apoptosis (staurosporine, etoposide, or camptothecin), and hmgb1 release into the medium was assessed by western blotting. |
2007-02-15 |
2023-08-12 |
Not clear |
| Charles W Bell, Weiwen Jiang, Charles F Reich, David S Pisetsk. The extracellular release of HMGB1 during apoptotic cell death. American journal of physiology. Cell physiology. vol 291. issue 6. 2007-02-15. PMID:16855214. |
in addition, hela cells induced to undergo apoptosis showed hmgb1 release. |
2007-02-15 |
2023-08-12 |
Not clear |
| Charles W Bell, Weiwen Jiang, Charles F Reich, David S Pisetsk. The extracellular release of HMGB1 during apoptotic cell death. American journal of physiology. Cell physiology. vol 291. issue 6. 2007-02-15. PMID:16855214. |
furthermore, we showed using confocal microscopy that hmgb1 and dna change their nuclear location in jurkat cells undergoing apoptosis. |
2007-02-15 |
2023-08-12 |
Not clear |
| Charles W Bell, Weiwen Jiang, Charles F Reich, David S Pisetsk. The extracellular release of HMGB1 during apoptotic cell death. American journal of physiology. Cell physiology. vol 291. issue 6. 2007-02-15. PMID:16855214. |
together, these studies indicate that hmgb1 release can occur during the course of apoptosis as well as necrosis and suggest that the release process may vary with cell type. |
2007-02-15 |
2023-08-12 |
Not clear |
| Shixin Qin, Haichao Wang, Renqi Yuan, Hui Li, Mahendar Ochani, Kanta Ochani, Mauricio Rosas-Ballina, Chris J Czura, Jared M Huston, Ed Miller, Xinchun Lin, Barbara Sherry, Anjali Kumar, Greg Larosa, Walter Newman, Kevin J Tracey, Huan Yan. Role of HMGB1 in apoptosis-mediated sepsis lethality. The Journal of experimental medicine. vol 203. issue 7. 2006-08-22. PMID:16818669. |
we found that z-vad-fmk-treated septic mice had decreased levels of high mobility group box 1 (hmgb1), a critical cytokine mediator of organ damage in severe sepsis, and suppressed apoptosis in the spleen and thymus. |
2006-08-22 |
2023-08-12 |
mouse |
| Shixin Qin, Haichao Wang, Renqi Yuan, Hui Li, Mahendar Ochani, Kanta Ochani, Mauricio Rosas-Ballina, Chris J Czura, Jared M Huston, Ed Miller, Xinchun Lin, Barbara Sherry, Anjali Kumar, Greg Larosa, Walter Newman, Kevin J Tracey, Huan Yan. Role of HMGB1 in apoptosis-mediated sepsis lethality. The Journal of experimental medicine. vol 203. issue 7. 2006-08-22. PMID:16818669. |
thus, our data indicate that hmgb1 production is downstream of apoptosis on the final common pathway to organ damage in severe sepsis. |
2006-08-22 |
2023-08-12 |
mouse |
| Francesca Riuzzi, Guglielmo Sorci, Rosario Donat. The amphoterin (HMGB1)/receptor for advanced glycation end products (RAGE) pair modulates myoblast proliferation, apoptosis, adhesiveness, migration, and invasiveness. Functional inactivation of RAGE in L6 myoblasts results in tumor formation in vivo. The Journal of biological chemistry. vol 281. issue 12. 2006-05-10. PMID:16407300. |
the amphoterin (hmgb1)/receptor for advanced glycation end products (rage) pair modulates myoblast proliferation, apoptosis, adhesiveness, migration, and invasiveness. |
2006-05-10 |
2023-08-12 |
mouse |
| K Völp, M-L Brezniceanu, S Bösser, T Brabletz, T Kirchner, D Göttel, S Joos, M Zörni. Increased expression of high mobility group box 1 (HMGB1) is associated with an elevated level of the antiapoptotic c-IAP2 protein in human colon carcinomas. Gut. vol 55. issue 2. 2006-02-13. PMID:16118352. |
overexpression of hmgb1 inhibits apoptosis, arguing that the molecule may act as an antiapoptotic oncoprotein. |
2006-02-13 |
2023-08-12 |
human |
| Thomas Jungas, Philippe Verbeke, Toni Darville, David M Ojciu. Cell death, BAX activation, and HMGB1 release during infection with Chlamydia. Microbes and infection. vol 6. issue 13. 2005-03-22. PMID:15488733. |
interestingly, both the epithelial cells and the fibroblasts also released high mobility group box 1 protein (hmgb1) during infection, although much less hmgb1 was released from fibroblasts, consistent with the higher level of apoptosis observed in the primary cells. |
2005-03-22 |
2023-08-12 |
mouse |
| Tomy Joseph, Arnost Cepica, Laura Brown, Basil O Ikede, Frederick S B Kibeng. Mechanism of cell death during infectious salmon anemia virus infection is cell type-specific. The Journal of general virology. vol 85. issue Pt 10. 2004-10-21. PMID:15448366. |
isav-infected to cells did not undergo apoptosis, but showed leakage of high-mobility group 1 (hmgb1) protein from the nucleus, which is characteristic of cells undergoing necrosis; this suggests that cpe in these cells is associated with necrosis. |
2004-10-21 |
2023-08-12 |
Not clear |
| Markus A Weigand, Christian Hörner, Hubert J Bardenheuer, Axel Boucho. The systemic inflammatory response syndrome. Best practice & research. Clinical anaesthesiology. vol 18. issue 3. 2004-09-07. PMID:15212339. |
promising new experimental treatment options are interference with mif, hmgb1, c5a or trem-1 signal transduction pathways and an inhibition of apoptosis, which may further improve the prognosis of septic patients in the future. |
2004-09-07 |
2023-08-12 |
Not clear |
| Ulf Andersson, Kevin J Trace. HMGB1 as a mediator of necrosis-induced inflammation and a therapeutic target in arthritis. Rheumatic diseases clinics of North America. vol 30. issue 3. 2004-09-07. PMID:15261345. |
hmgb1 is passively released during cell necrosis, but not apoptosis; it activates an inflammatory response to necrosis,but not apoptosis. |
2004-09-07 |
2023-08-12 |
Not clear |
| Marie-Luise Brezniceanu, Kirsten Völp, Susanne Bösser, Christine Solbach, Peter Lichter, Stefan Joos, Martin Zörni. HMGB1 inhibits cell death in yeast and mammalian cells and is abundantly expressed in human breast carcinoma. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 17. issue 10. 2003-07-17. PMID:12759333. |
hmgb1 is also able to protect mammalian cells against different death stimuli including ultraviolet radiation, cd95-, trail-, casp-8-, and bax-induced apoptosis. |
2003-07-17 |
2023-08-12 |
mouse |
| Marie-Luise Brezniceanu, Kirsten Völp, Susanne Bösser, Christine Solbach, Peter Lichter, Stefan Joos, Martin Zörni. HMGB1 inhibits cell death in yeast and mammalian cells and is abundantly expressed in human breast carcinoma. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 17. issue 10. 2003-07-17. PMID:12759333. |
these data suggest that hmgb1 may participate in the regulation of mammary gland apoptosis and that its high expression level promotes tumor growth because of its anti-apoptotic properties. |
2003-07-17 |
2023-08-12 |
mouse |