| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| H Sugiyama, J S Savill, M Kitamura, L Zhao, E Styliano. Selective sensitization to tumor necrosis factor-alpha-induced apoptosis by blockade of NF-kappaB in primary glomerular mesangial cells. The Journal of biological chemistry. vol 274. issue 28. 1999-08-05. PMID:10391885. |
ikappabalpham significantly sensitized mesangial cells to tnf-alpha-induced apoptosis in a dose- and time-dependent manner but had no significant effects on the level of apoptosis in the presence of proinflammatory or apoptosis-inducing stimuli including fas ligand, il-1alpha, il-1beta, hydrogen peroxide, lipopolysaccharide, cycloheximide, or serum deprivation. |
1999-08-05 |
2023-08-12 |
rat |
| H Sugiyama, J S Savill, M Kitamura, L Zhao, E Styliano. Selective sensitization to tumor necrosis factor-alpha-induced apoptosis by blockade of NF-kappaB in primary glomerular mesangial cells. The Journal of biological chemistry. vol 274. issue 28. 1999-08-05. PMID:10391885. |
these data show that inhibition of nf-kappab selectively sensitizes primary adult glomerular mesangial cells to tnf-induced apoptosis but not to other mediators of cell death including the fas ligand. |
1999-08-05 |
2023-08-12 |
rat |
| K Kuwano, N Hagimoto, M Kawasaki, T Yatomi, N Nakamura, S Nagata, T Suda, R Kunitake, T Maeyama, H Miyazaki, N Har. Essential roles of the Fas-Fas ligand pathway in the development of pulmonary fibrosis. The Journal of clinical investigation. vol 104. issue 1. 1999-08-05. PMID:10393694. |
previously, we found excessive apoptosis of epithelial cells and infiltrating lymphocytes expressing fas ligand mrna in the lung tissue of bleomycin-induced pulmonary fibrosis in mice. |
1999-08-05 |
2023-08-12 |
mouse |
| S Brochu, B Rioux-Massé, J Roy, D C Roy, C Perreaul. Massive activation-induced cell death of alloreactive T cells with apoptosis of bystander postthymic T cells prevents immune reconstitution in mice with graft-versus-host disease. Blood. vol 94. issue 2. 1999-08-05. PMID:10397705. |
second, whereas non-host-reactive donor t cells neither upregulated fas nor suffered apoptosis when transplanted alone, they showed increased membrane fas expression and apoptosis when coinjected with host-reactive t cells. |
1999-08-05 |
2023-08-12 |
mouse |
| E C Shin, J S Shin, J H Park, H Kim, S J Ki. Expression of fas ligand in human hepatoma cell lines: role of hepatitis-B virus X (HBX) in induction of Fas ligand. International journal of cancer. vol 82. issue 4. 1999-08-05. PMID:10404075. |
it has been postulated that tumor cells expressing fas ligand (fasl) can evade immune surveillance by inducing apoptosis in t cells expressing fas. |
1999-08-05 |
2023-08-12 |
human |
| M R Young, M A Wright, D M Lathers, K A Messingha. Increased resistance to apoptosis by bone marrow CD34(+)progenitor cells from tumor-bearing mice. International journal of cancer. vol 82. issue 4. 1999-08-05. PMID:10404079. |
whereas approximately half of the normal cd34(+) cells underwent apoptosis in response to fas ligation, the tumor-exposed cd34(+) cells resisted apoptosis, even though their surface fas expression was greater than that of normal cd34(+) cells. |
1999-08-05 |
2023-08-12 |
mouse |
| R W Watson, A O'Neill, A E Brannigan, A E Brannigen, R Coffey, J C Marshall, H R Brady, J M Fitzpatric. Regulation of Fas antibody induced neutrophil apoptosis is both caspase and mitochondrial dependent. FEBS letters. vol 453. issue 1-2. 1999-08-02. PMID:10403377. |
regulation of fas antibody induced neutrophil apoptosis is both caspase and mitochondrial dependent. |
1999-08-02 |
2023-08-12 |
Not clear |
| R W Watson, A O'Neill, A E Brannigan, A E Brannigen, R Coffey, J C Marshall, H R Brady, J M Fitzpatric. Regulation of Fas antibody induced neutrophil apoptosis is both caspase and mitochondrial dependent. FEBS letters. vol 453. issue 1-2. 1999-08-02. PMID:10403377. |
we conclude inhibition of fas antibody induced apoptosis by inflammatory proteins is associated with augmented mitochondrial stability and reduced caspase 3 activity that may be glutathione mediated. |
1999-08-02 |
2023-08-12 |
Not clear |
| J Houghton, R M Korah, K H Ki. Fas receptor up-regulation and membrane localization concurrent with apoptosis in idiopathic esophageal ulceration: toward a better understanding of esophageal injury in AIDS. The Journal of infectious diseases. vol 180. issue 1. 1999-07-29. PMID:10353883. |
fas receptor up-regulation and membrane localization concurrent with apoptosis in idiopathic esophageal ulceration: toward a better understanding of esophageal injury in aids. |
1999-07-29 |
2023-08-12 |
Not clear |
| J Houghton, R M Korah, K H Ki. Fas receptor up-regulation and membrane localization concurrent with apoptosis in idiopathic esophageal ulceration: toward a better understanding of esophageal injury in AIDS. The Journal of infectious diseases. vol 180. issue 1. 1999-07-29. PMID:10353883. |
concomitant increase in the basic components of fas machinery, together with elevated mucosal apoptosis, strongly suggests the potential role of the fas signaling pathway in the onset of tissue destruction associated with ieus. |
1999-07-29 |
2023-08-12 |
Not clear |
| W Hashimoto, T Osaki, H Okamura, P D Robbins, M Kurimoto, S Nagata, M T Lotze, H Tahar. Differential antitumor effects of administration of recombinant IL-18 or recombinant IL-12 are mediated primarily by Fas-Fas ligand- and perforin-induced tumor apoptosis, respectively. Journal of immunology (Baltimore, Md. : 1950). vol 163. issue 2. 1999-07-29. PMID:10395644. |
since il-18 enhances fas ligand (fasl) expression on nk cell lines, the il-18 antitumor effects could be mediated by fasl-induced cross-linking of fas and subsequent tumor apoptosis. |
1999-07-29 |
2023-08-12 |
mouse |
| V Kolenko, T Bloom, P Rayman, R Bukowski, E Hsi, J Fink. Inhibition of NF-kappa B activity in human T lymphocytes induces caspase-dependent apoptosis without detectable activation of caspase-1 and -3. Journal of immunology (Baltimore, Md. : 1950). vol 163. issue 2. 1999-07-29. PMID:10395645. |
interestingly, apoptosis induced by nf-kappa b suppression, in contrast to that induced by tpen (n,n,n',n'-tetrakis [2-pyridylmethyl]ethylenediamine) or soluble fas ligand (cd95), was observed in the absence of active death effector proteases caspase-1-like (il-1 converting enzyme), caspase-3-like (cpp32/yama/apopain), and caspase-6-like and without cleavage of caspase-3 substrates poly(adp-ribose) polymerase and dna fragmentation factor-45. |
1999-07-29 |
2023-08-12 |
human |
| K Ina, J Itoh, K Fukushima, K Kusugami, T Yamaguchi, K Kyokane, A Imada, D G Binion, A Musso, G A West, G M Dobrea, T S McCormick, E G Lapetina, A D Levine, C A Ottaway, C Fiocch. Resistance of Crohn's disease T cells to multiple apoptotic signals is associated with a Bcl-2/Bax mucosal imbalance. Journal of immunology (Baltimore, Md. : 1950). vol 163. issue 2. 1999-07-29. PMID:10395708. |
t cell apoptosis was induced by il-2 deprivation, fas ag ligation, and exposure to tnf-alpha and nitric oxide. |
1999-07-29 |
2023-08-12 |
Not clear |
| J Haux, A C Johnsen, B Steinkjer, K Egeberg, A Sundan, T Espevi. The role of interleukin-2 in regulating the sensitivity of natural killer cells for Fas-mediated apoptosis. Cancer immunology, immunotherapy : CII. vol 48. issue 2-3. 1999-07-29. PMID:10414468. |
in contrast, nk cells cultivated in il-2 for 6 days became sensitive to ch11-induced apoptosis without addition of actinomycin d. at this time, a pronounced up-regulation of the fas protein on the nk cell membrane was detected. |
1999-07-29 |
2023-08-12 |
human |
| R K Singh, M L Varney, S Buyukberber, K Ino, A G Ageitos, E Reed, S Tarantolo, J E Talmadg. Fas-FasL-mediated CD4+ T-cell apoptosis following stem cell transplantation. Cancer research. vol 59. issue 13. 1999-07-28. PMID:10397252. |
the preferential expression of fas on cd4+ t cells (73-92%) in the peripheral blood (pb) of these patients is associated with a significantly higher frequency of cd4+ t-cell apoptosis compared with cd8+ t cells (28-47%) and cd4+ t cells (46 +/- 5.7%) in normal pb. |
1999-07-28 |
2023-08-12 |
Not clear |
| D Coppola, B Saunders, L Fu, W Mao, S V Nicosi. The insulin-like growth factor 1 receptor induces transformation and tumorigenicity of ovarian mesothelial cells and down-regulates their Fas-receptor expression. Cancer research. vol 59. issue 13. 1999-07-28. PMID:10397275. |
igf-1r may down-regulate the fas expression rendering transformed ovarian mesothelial cells resistant to apoptosis. |
1999-07-28 |
2023-08-12 |
mouse |
| Y Nakamoto, S Kaneko, S W Buttner, E Matsushita, K Kobayash. Inhibition of peripheral blood lymphocyte apoptosis by soluble fas ligand in patients with hepatocellular carcinoma. Oncology reports. vol 6. issue 4. 1999-07-27. PMID:10373647. |
inhibition of peripheral blood lymphocyte apoptosis by soluble fas ligand in patients with hepatocellular carcinoma. |
1999-07-27 |
2023-08-12 |
Not clear |
| Y Nakamoto, S Kaneko, S W Buttner, E Matsushita, K Kobayash. Inhibition of peripheral blood lymphocyte apoptosis by soluble fas ligand in patients with hepatocellular carcinoma. Oncology reports. vol 6. issue 4. 1999-07-27. PMID:10373647. |
we monitored apoptosis of peripheral blood lymphocytes (pbl) obtained from patients with various degrees of chronic viral hepatitis, including hepatocellular carcinoma (hcc), in vitro and quantitated the serum levels of soluble fas ligand (fasl) by elisa. |
1999-07-27 |
2023-08-12 |
Not clear |
| N Favre, B Bonnotte, N Droin, A Fromentin, E Solary, F Marti. FAS(CD95) ligand expression by tumor cell variants can be unrelated to their capacity to induce tolerance or immune rejection. International journal of cancer. vol 82. issue 3. 1999-07-27. PMID:10399953. |
according to the results of in vitro experiments, fas(cd95) ligand expression by cancer cells might induce apoptosis of activated t cells and contribute to immune tolerance. |
1999-07-27 |
2023-08-12 |
rat |
| H S Liao, A Matsumoto, H Itakura, T Pittman, T Kodama, Y J Gen. De novo expression of the class-A macrophage scavenger receptor conferring resistance to apoptosis in differentiated human THP-1 monocytic cells. Cell death and differentiation. vol 6. issue 3. 1999-07-26. PMID:10200575. |
the phorbol ester-stimulated thp-1 cells also expressed increased levels of the pro-apoptotic gene products, caspase-3 and fas ligand, but the cells exhibited no change in apoptosis. |
1999-07-26 |
2023-08-12 |
human |