| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| H C Hsu, T Thomas, L H Sigal, T J Thoma. Polyamine-fas interactions: inhibition of polyamine biosynthesis in MRL-lpr/lpr mice is associated with the up-regulation of fas mRNA in thymocytes. Autoimmunity. vol 29. issue 4. 1999-08-24. PMID:10433086. |
the lpr (lymphoproliferation) defect has been identified as an insertion of an early transposon (etn) derived sequence into the fas apoptosis gene. |
1999-08-24 |
2023-08-12 |
mouse |
| M S Lee, S Kim, J H Chung, M K Lee, K W Ki. Fas is expressed in murine pancreatic islet cells and an insulinoma cell line but does not mediate their apoptosis in vitro. Autoimmunity. vol 29. issue 3. 1999-08-24. PMID:10433099. |
fas is expressed in murine pancreatic islet cells and an insulinoma cell line but does not mediate their apoptosis in vitro. |
1999-08-24 |
2023-08-12 |
mouse |
| M S Lee, S Kim, J H Chung, M K Lee, K W Ki. Fas is expressed in murine pancreatic islet cells and an insulinoma cell line but does not mediate their apoptosis in vitro. Autoimmunity. vol 29. issue 3. 1999-08-24. PMID:10433099. |
our data indicate that pancreatic beta-islet cells express a small amount of fas molecules but fas molecules do not mediate apoptosis of islet cells at least in vitro. |
1999-08-24 |
2023-08-12 |
mouse |
| L Zhang, J Chen, H F. Suppression of apoptosis signal-regulating kinase 1-induced cell death by 14-3-3 proteins. Proceedings of the National Academy of Sciences of the United States of America. vol 96. issue 15. 1999-08-23. PMID:10411906. |
apoptosis signal-regulating kinase 1 (ask1) is a pivotal component of a signaling pathway induced by many death stimuli, including tumor necrosis factor alpha, fas, and the anticancer drugs cisplatin and paclitaxel. |
1999-08-23 |
2023-08-12 |
Not clear |
| A Hayakawa, I Yokoyama, H Tajiri, T Okamoto, I Nakashim. Protein kinase C-dependent anti-apoptotic mechanism that is associated with high sensitivity to anti-Fas antibody in ovarian cancer cell lines. Cancer letters. vol 140. issue 1-2. 1999-08-19. PMID:10403549. |
we compared the sensitivities to apoptosis via anti-fas antibody of two human ovarian cancer cell lines, nos4 and skov-3, both of which strongly express the fas antigen on their cell surface. |
1999-08-19 |
2023-08-12 |
human |
| H Ungefroren, M Voss, W V Bernstorff, A Schmid, B Kremer, H Kalthof. Immunological escape mechanisms in pancreatic carcinoma. Annals of the New York Academy of Sciences. vol 880. 1999-08-19. PMID:10415870. |
despite fas expression the majority of cell lines was resistant to fas-mediated apoptosis. |
1999-08-19 |
2023-08-12 |
Not clear |
| Y Hiromatsu, T Hoshino, H Yagita, M Koga, S Sakisaka, J Honda, D Yang, N Kayagaki, K Okumura, K Nonak. Functional Fas ligand expression in thyrocytes from patients with Graves' disease. The Journal of clinical endocrinology and metabolism. vol 84. issue 8. 1999-08-19. PMID:10443697. |
coculture with thyrocytes induced apoptosis of fas transfectants, which was blocked by an anti-fasl antibody. |
1999-08-19 |
2023-08-12 |
Not clear |
| N Mitsiades, V Poulaki, G Mastorakos, S T Tseleni-Balafouta, V Kotoula, D A Koutras, M Tsoko. Fas ligand expression in thyroid carcinomas: a potential mechanism of immune evasion. The Journal of clinical endocrinology and metabolism. vol 84. issue 8. 1999-08-19. PMID:10443700. |
fas ligand (fasl) induces apoptosis by cross-linking the fas receptor and is expressed by cells of the immune system. |
1999-08-19 |
2023-08-12 |
Not clear |
| N Mitsiades, V Poulaki, G Mastorakos, S T Tseleni-Balafouta, V Kotoula, D A Koutras, M Tsoko. Fas ligand expression in thyroid carcinomas: a potential mechanism of immune evasion. The Journal of clinical endocrinology and metabolism. vol 84. issue 8. 1999-08-19. PMID:10443700. |
cross-linking of fas induced apoptosis in thyroid carcinoma cells only in the presence of cycloheximide. |
1999-08-19 |
2023-08-12 |
Not clear |
| F Blankenberg, K Ohtsuki, H W Straus. Dying a thousand deaths. Radionuclide imaging of apoptosis. The quarterly journal of nuclear medicine : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR). vol 43. issue 2. 1999-08-18. PMID:10429513. |
apoptosis can also be induced by external signals, such as interaction of fas ligand with fas receptors. |
1999-08-18 |
2023-08-12 |
Not clear |
| D N Posnett, J W Edinger, J S Manavalan, C Irwin, G Marodo. Differentiation of human CD8 T cells: implications for in vivo persistence of CD8+ CD28- cytotoxic effector clones. International immunology. vol 11. issue 2. 1999-08-17. PMID:10069421. |
cd95 (fas) expression was lower in cd8+ cd28- cells, and this subset was less prone to spontaneous apoptosis in ex vivo samples and more resistant to activation-induced cell death induced by a superantigen in vitro. |
1999-08-17 |
2023-08-12 |
human |
| M F Taylor, M de Boer-Brouwer, I Woolveridge, K J Teerds, I D Morri. Leydig cell apoptosis after the administration of ethane dimethanesulfonate to the adult male rat is a Fas-mediated process. Endocrinology. vol 140. issue 8. 1999-08-17. PMID:10433241. |
we also investigated the role of the fas system in leydig cell apoptosis. |
1999-08-17 |
2023-08-12 |
rat |
| M F Taylor, M de Boer-Brouwer, I Woolveridge, K J Teerds, I D Morri. Leydig cell apoptosis after the administration of ethane dimethanesulfonate to the adult male rat is a Fas-mediated process. Endocrinology. vol 140. issue 8. 1999-08-17. PMID:10433241. |
however, up-regulation of the fas system does occur, implicating activation of fas receptor in the induction of leydig cell apoptosis. |
1999-08-17 |
2023-08-12 |
rat |
| S J Wei, Y Chao, Y L Shih, D M Yang, Y M Hung, W K Yan. Involvement of Fas (CD95/APO-1) and Fas ligand in apoptosis induced by ganciclovir treatment of tumor cells transduced with herpes simplex virus thymidine kinase. Gene therapy. vol 6. issue 3. 1999-08-17. PMID:10435092. |
involvement of fas (cd95/apo-1) and fas ligand in apoptosis induced by ganciclovir treatment of tumor cells transduced with herpes simplex virus thymidine kinase. |
1999-08-17 |
2023-08-12 |
Not clear |
| S J Wei, Y Chao, Y L Shih, D M Yang, Y M Hung, W K Yan. Involvement of Fas (CD95/APO-1) and Fas ligand in apoptosis induced by ganciclovir treatment of tumor cells transduced with herpes simplex virus thymidine kinase. Gene therapy. vol 6. issue 3. 1999-08-17. PMID:10435092. |
immunoblot analyses revealed that fas (cd95/apo-1), fas ligand (fasl) and two downstream mediators, rip and caspase-3, (cpp32, yama, apopain) were increased in gcv-treated hsvtk-transduced tumor cells the cell cycle arrest and before apoptosis. |
1999-08-17 |
2023-08-12 |
Not clear |
| K Kühn, S Hashimoto, M Lot. Cell density modulates apoptosis in human articular chondrocytes. Journal of cellular physiology. vol 180. issue 3. 1999-08-16. PMID:10430184. |
this study addresses the effects of cell density and serum on cd95 (apo-1/fas) and cd95l (fas ligand) expression and on the induction of cd95-dependent apoptosis in human articular chondrocytes from normal knees. |
1999-08-16 |
2023-08-12 |
human |
| R K Srivastava, C Y Sasaki, J M Hardwick, D L Long. Bcl-2-mediated drug resistance: inhibition of apoptosis by blocking nuclear factor of activated T lymphocytes (NFAT)-induced Fas ligand transcription. The Journal of experimental medicine. vol 190. issue 2. 1999-08-16. PMID:10432288. |
bcl-2-mediated drug resistance: inhibition of apoptosis by blocking nuclear factor of activated t lymphocytes (nfat)-induced fas ligand transcription. |
1999-08-16 |
2023-08-12 |
Not clear |
| C Olive, C Cheung, M C Fal. Apoptosis and expression of cytotoxic T lymphocyte effector molecules in renal allografts. Transplant immunology. vol 7. issue 1. 1999-08-12. PMID:10375075. |
the two major effector pathways of ctl killing which lead to apoptosis involve the fas/fas ligand (fas l) lytic pathway, and the perforin/granzyme degranulation pathway. |
1999-08-12 |
2023-08-12 |
Not clear |
| J Bajorat. Identification of the ligand binding site in Fas (CD95) and analysis of Fas-ligand interactions. Proteins. vol 35. issue 4. 1999-08-12. PMID:10382675. |
fas (cd95), a member of the tumor necrosis factor receptor superfamily, and its ligand (fasl), a tumor necrosis factor-like protein, are intensely studied because their interaction on the cell surface is critical for the induction of programmed cell death (apoptosis) and the regulation of immune responses. |
1999-08-12 |
2023-08-12 |
Not clear |
| A Ashkenazi, R C Pai, S Fong, S Leung, D A Lawrence, S A Marsters, C Blackie, L Chang, A E McMurtrey, A Hebert, L DeForge, I L Koumenis, D Lewis, L Harris, J Bussiere, H Koeppen, Z Shahrokh, R H Schwal. Safety and antitumor activity of recombinant soluble Apo2 ligand. The Journal of clinical investigation. vol 104. issue 2. 1999-08-12. PMID:10411544. |
tnf and fas ligand induce apoptosis in tumor cells; however, their severe toxicity toward normal tissues hampers their application to cancer therapy. |
1999-08-12 |
2023-08-12 |
mouse |