Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
M Jenkins, M Keir, J M McCun. Fas is expressed early in human thymocyte development but does not transmit an apoptotic signal. Journal of immunology (Baltimore, Md. : 1950). vol 163. issue 3. 1999-08-12. PMID:10415014. |
mouse thymocytes were induced to apoptosis by cross-linked recombinant soluble human fas ligand both in vitro and in vivo, though human thymocytes were also resistant to this mode of receptor ligation. |
1999-08-12 |
2023-08-12 |
mouse |
M Jenkins, M Keir, J M McCun. Fas is expressed early in human thymocyte development but does not transmit an apoptotic signal. Journal of immunology (Baltimore, Md. : 1950). vol 163. issue 3. 1999-08-12. PMID:10415014. |
these data demonstrate a durable and specific resistance of human thymocytes to apoptosis induced through fas receptor engagement, and reveal significant species-specific differences in the biology of thymocyte-programmed cell death. |
1999-08-12 |
2023-08-12 |
mouse |
M Inaba, K Kurasawa, M Mamura, K Kumano, Y Saito, I Iwamot. Primed T cells are more resistant to Fas-mediated activation-induced cell death than naive T cells. Journal of immunology (Baltimore, Md. : 1950). vol 163. issue 3. 1999-08-12. PMID:10415029. |
we further showed that the resistance to aicd in primed t cells was due to the decreased sensitivity to apoptosis induced by fas-mediated signals, but tcr-mediated signaling equally activated both naive and primed t cells to induce fas and fas ligand expressions. |
1999-08-12 |
2023-08-12 |
mouse |
H E Thomas, R Darwiche, J A Corbett, T W Ka. Evidence that beta cell death in the nonobese diabetic mouse is Fas independent. Journal of immunology (Baltimore, Md. : 1950). vol 163. issue 3. 1999-08-12. PMID:10415060. |
last, we show that no is not required for cytokine-induced fas expression and fas-mediated apoptosis of islet cells. |
1999-08-12 |
2023-08-12 |
mouse |
J Peake, A Waugh, F Le Deist, A Priestley, F Rieux-Laucat, N Foray, E Capulas, B K Singleton, J P de Villartay, A Cant, E P Malaise, A Fischer, C Hivroz, P A Jegg. Combined immunodeficiency associated with increased apoptosis of lymphocytes and radiosensitivity fibroblasts. Cancer research. vol 59. issue 14. 1999-08-12. PMID:10416610. |
the elevated apoptosis was not due to alterations in expression or to mutations in bcl-2, bcl-x(l), or flip, nor could the spontaneous apoptosis be prevented by blocking fas, suggesting that it was independent of fas signaling. |
1999-08-12 |
2023-08-12 |
Not clear |
G A Martins, L Q Vieira, F Q Cunha, J S Silv. Gamma interferon modulates CD95 (Fas) and CD95 ligand (Fas-L) expression and nitric oxide-induced apoptosis during the acute phase of Trypanosoma cruzi infection: a possible role in immune response control. Infection and immunity. vol 67. issue 8. 1999-08-12. PMID:10417150. |
gamma interferon modulates cd95 (fas) and cd95 ligand (fas-l) expression and nitric oxide-induced apoptosis during the acute phase of trypanosoma cruzi infection: a possible role in immune response control. |
1999-08-12 |
2023-08-12 |
mouse |
G A Martins, L Q Vieira, F Q Cunha, J S Silv. Gamma interferon modulates CD95 (Fas) and CD95 ligand (Fas-L) expression and nitric oxide-induced apoptosis during the acute phase of Trypanosoma cruzi infection: a possible role in immune response control. Infection and immunity. vol 67. issue 8. 1999-08-12. PMID:10417150. |
the addition of recombinant murine ifn-gamma to spleen cells cultures from infected ifn-gamma(-/-) mice increased apoptosis levels, fas expression, and no production. |
1999-08-12 |
2023-08-12 |
mouse |
G A Martins, L Q Vieira, F Q Cunha, J S Silv. Gamma interferon modulates CD95 (Fas) and CD95 ligand (Fas-L) expression and nitric oxide-induced apoptosis during the acute phase of Trypanosoma cruzi infection: a possible role in immune response control. Infection and immunity. vol 67. issue 8. 1999-08-12. PMID:10417150. |
in the presence of ifn-gamma and absence of no, although fas expression was maintained, apoptosis levels were significantly reduced but still higher than those found in splenocytes from uninfected mice, suggesting that fas-fas-l interaction could also play a role in apoptosis induction in t. cruzi-infected mice. |
1999-08-12 |
2023-08-12 |
mouse |
G A Martins, L Q Vieira, F Q Cunha, J S Silv. Gamma interferon modulates CD95 (Fas) and CD95 ligand (Fas-L) expression and nitric oxide-induced apoptosis during the acute phase of Trypanosoma cruzi infection: a possible role in immune response control. Infection and immunity. vol 67. issue 8. 1999-08-12. PMID:10417150. |
moreover, in vivo, the treatment of infected wt mice with the inducible nitric oxide synthase inhibitor aminoguanidine also led to decreased no and apoptosis levels but not fas expression, suggesting that ifn-gamma modulates apoptosis induction by two independent and distinct mechanisms: induction of no production and of fas and fas-l expression. |
1999-08-12 |
2023-08-12 |
mouse |
N Koide, K Narita, Y Kato, T Sugiyama, D Chakravortty, A Morikawa, T Yoshida, T Yokoch. Expression of Fas and Fas ligand on mouse renal tubular epithelial cells in the generalized shwartzman reaction and its relationship to apoptosis. Infection and immunity. vol 67. issue 8. 1999-08-12. PMID:10417181. |
expression of fas and fas ligand on mouse renal tubular epithelial cells in the generalized shwartzman reaction and its relationship to apoptosis. |
1999-08-12 |
2023-08-12 |
mouse |
N Koide, K Narita, Y Kato, T Sugiyama, D Chakravortty, A Morikawa, T Yoshida, T Yokoch. Expression of Fas and Fas ligand on mouse renal tubular epithelial cells in the generalized shwartzman reaction and its relationship to apoptosis. Infection and immunity. vol 67. issue 8. 1999-08-12. PMID:10417181. |
the administration of anti-gamma interferon antibody together with a preparative injection of lps prevented the expression of fas and fas ligand and the apoptosis of renal tubular epithelial cells. |
1999-08-12 |
2023-08-12 |
mouse |
N Koide, K Narita, Y Kato, T Sugiyama, D Chakravortty, A Morikawa, T Yoshida, T Yokoch. Expression of Fas and Fas ligand on mouse renal tubular epithelial cells in the generalized shwartzman reaction and its relationship to apoptosis. Infection and immunity. vol 67. issue 8. 1999-08-12. PMID:10417181. |
a provocative injection of tumor necrosis factor alpha into lps-sensitized mice augmented fas and fas ligand expression and the apoptosis of renal tubular epithelial cells. |
1999-08-12 |
2023-08-12 |
mouse |
N Koide, K Narita, Y Kato, T Sugiyama, D Chakravortty, A Morikawa, T Yoshida, T Yokoch. Expression of Fas and Fas ligand on mouse renal tubular epithelial cells in the generalized shwartzman reaction and its relationship to apoptosis. Infection and immunity. vol 67. issue 8. 1999-08-12. PMID:10417181. |
the administration of tumor necrosis factor alpha to interleukin-12-sensitized mice resulted in fas and fas ligand expression and the apoptosis. |
1999-08-12 |
2023-08-12 |
mouse |
N L Jones, A S Day, H A Jennings, P M Sherma. Helicobacter pylori induces gastric epithelial cell apoptosis in association with increased Fas receptor expression. Infection and immunity. vol 67. issue 8. 1999-08-12. PMID:10417197. |
helicobacter pylori induces gastric epithelial cell apoptosis in association with increased fas receptor expression. |
1999-08-12 |
2023-08-12 |
human |
N L Jones, A S Day, H A Jennings, P M Sherma. Helicobacter pylori induces gastric epithelial cell apoptosis in association with increased Fas receptor expression. Infection and immunity. vol 67. issue 8. 1999-08-12. PMID:10417197. |
in addition to stimulating apoptosis, infection with h. pylori enhanced fas receptor expression in ags cells to a degree comparable to that of treatment with a positive control, gamma interferon (12.5 ng/ml) (148% +/- 24% and 167% +/- 24% of control, respectively). |
1999-08-12 |
2023-08-12 |
human |
N L Jones, A S Day, H A Jennings, P M Sherma. Helicobacter pylori induces gastric epithelial cell apoptosis in association with increased Fas receptor expression. Infection and immunity. vol 67. issue 8. 1999-08-12. PMID:10417197. |
ligation of the fas receptor with an agonistic monoclonal antibody resulted in an increase in apoptosis compared to the apoptosis of cells infected with the bacterium alone (38.5% +/- 7.1% versus 16.0% +/- 2.8%, p < 0.05). |
1999-08-12 |
2023-08-12 |
human |
N L Jones, A S Day, H A Jennings, P M Sherma. Helicobacter pylori induces gastric epithelial cell apoptosis in association with increased Fas receptor expression. Infection and immunity. vol 67. issue 8. 1999-08-12. PMID:10417197. |
taken together, these findings demonstrate that the gastric pathogen h. pylori stimulates apoptosis of gastric epithelial cells in vitro in association with the enhanced expression of the fas receptor. |
1999-08-12 |
2023-08-12 |
human |
M Saito, N Nakamura, M Nagai, K Shirakawa, H Sato, N Kawahigashi, Y Furukawa, K Usuku, M Nakagawa, S Izumo, M Osam. Increased levels of soluble Fas ligand in CSF of rapidly progressive HTLV-1-associated myelopathy/tropical spastic paraparesis patients. Journal of neuroimmunology. vol 98. issue 2. 1999-08-12. PMID:10430056. |
the interaction of fas ligand (fasl) with fas-bearing cells induces apoptosis and contributes to the negative regulation of peripheral t-cell responses. |
1999-08-12 |
2023-08-12 |
Not clear |
J Wang, L Zheng, A Lobito, F K Chan, J Dale, M Sneller, X Yao, J M Puck, S E Straus, M J Lenard. Inherited human Caspase 10 mutations underlie defective lymphocyte and dendritic cell apoptosis in autoimmune lymphoproliferative syndrome type II. Cell. vol 98. issue 1. 1999-08-09. PMID:10412980. |
these encode amino acid substitutions that decrease caspase activity and interfere with death receptor-induced apoptosis, particularly that stimulated by fas ligand and trail. |
1999-08-09 |
2023-08-12 |
human |
M Adamczyk, G Kostka, D Palu. [The role of apoptosis in cell physiology and pathology]. Roczniki Panstwowego Zakladu Higieny. vol 49. issue 4. 1999-08-06. PMID:10224887. |
extracellular signals, such as various growth factors and antigen fas ligand can trigger apoptosis via cell surface receptors. |
1999-08-06 |
2023-08-12 |
Not clear |