| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J H Ahn, Y G Ko, W Y Park, Y S Kang, H Y Chung, J S Se. Suppression of ceramide-mediated apoptosis by HSP70. Molecules and cells. vol 9. issue 2. 1999-07-09. PMID:10340476. |
ceramide has been known as an important second messenger in programmed cell death (apoptosis) which is induced by various stimuli such as the tumor necrosis factor-alpha (tnf-alpha), fas ligand, and environmental stresses such as uv-irradiation and heat shock. |
1999-07-09 |
2023-08-12 |
Not clear |
| J H Ahn, Y G Ko, W Y Park, Y S Kang, H Y Chung, J S Se. Suppression of ceramide-mediated apoptosis by HSP70. Molecules and cells. vol 9. issue 2. 1999-07-09. PMID:10340476. |
in t-cell hybridoma do11.10, we examined the effect of hsp70 on apoptosis mediated by tnf-alpha, fas ligation, smase, and c2-ceramide, all of which elevate intracellular ceramide levels. |
1999-07-09 |
2023-08-12 |
Not clear |
| D Coppola, R H Schreiber, L Mora, W Dalton, R C Kar. Significance of Fas and retinoblastoma protein expression during the progression of Barrett's metaplasia to adenocarcinoma. Annals of surgical oncology. vol 6. issue 3. 1999-07-08. PMID:10340890. |
recently, the fas receptor and retinoblastoma (rb) protein have been described as important mediators of apoptosis and tumor suppression, respectively. |
1999-07-08 |
2023-08-12 |
Not clear |
| S Hiroyasu, M Shiraishi, T Koji, T Mamadi, H Sugawa, Y Mut. Analysis of the Fas system and Bcl-2 in rat liver allograft rejection. The Journal of surgical research. vol 84. issue 2. 1999-07-08. PMID:10357921. |
the liver cells are sensitive to fas-mediated apoptosis; however, little is known about the involvement of the fas system in liver allograft rejection. |
1999-07-08 |
2023-08-12 |
rat |
| M P Pende. Activation-induced apoptosis of autoreactive and alloreactive T lymphocytes in the target organ as a major mechanism of tolerance. Immunology and cell biology. vol 77. issue 3. 1999-07-08. PMID:10361253. |
it is proposed that when activated autoreactive t cells enter the target organ, they are reactivated mainly by non-professional antigen-presenting cells (apc) and deleted by activation-induced apoptosis through the fas (cd95) pathway before producing significant target organ damage. |
1999-07-08 |
2023-08-12 |
Not clear |
| A de la Taille, M W Chen, A Shabsigh, E Bagiella, A Kiss, R Buttya. Fas antigen/CD-95 upregulation and activation during castration-induced regression of the rat ventral prostate gland. The Prostate. vol 40. issue 2. 1999-07-08. PMID:10386469. |
fas antigen/cd 95 is a 45-kda transmembrane protein that can initiate intracellular signaling pathways, leading to apoptosis when it is clustered on the cell surface. |
1999-07-08 |
2023-08-12 |
mouse |
| A de la Taille, M W Chen, A Shabsigh, E Bagiella, A Kiss, R Buttya. Fas antigen/CD-95 upregulation and activation during castration-induced regression of the rat ventral prostate gland. The Prostate. vol 40. issue 2. 1999-07-08. PMID:10386469. |
a recent report claiming that the ventral prostate glands of lpr -/- mutant mice (lacking functional fas antigen) do not regress following castration prompted our analysis of the regressing rat ventral prostate gland for evidence that fas antigen might participate in the molecular process leading to prostate cell apoptosis after castration. |
1999-07-08 |
2023-08-12 |
mouse |
| D A Rigberg, J Centeno, F S Kim, B Ke, K Swenson, M Maggard, D W McFadde. Irradiation-induced up-regulation of Fas in esophageal squamous cell carcinoma is not accompanied by Fas ligand-mediated apoptosis. Journal of surgical oncology. vol 71. issue 2. 1999-07-08. PMID:10389864. |
irradiation-induced up-regulation of fas in esophageal squamous cell carcinoma is not accompanied by fas ligand-mediated apoptosis. |
1999-07-08 |
2023-08-12 |
Not clear |
| D A Rigberg, J Centeno, F S Kim, B Ke, K Swenson, M Maggard, D W McFadde. Irradiation-induced up-regulation of Fas in esophageal squamous cell carcinoma is not accompanied by Fas ligand-mediated apoptosis. Journal of surgical oncology. vol 71. issue 2. 1999-07-08. PMID:10389864. |
fas (apo-1) induces apoptosis after binding fas ligand (fasl). |
1999-07-08 |
2023-08-12 |
Not clear |
| H Takahashi, S Nakamura, K Asano, M Kinouchi, A Ishida-Yamamoto, H Iizuk. Fas antigen modulates ultraviolet B-induced apoptosis of SVHK cells: sequential activation of caspases 8, 3, and 1 in the apoptotic process. Experimental cell research. vol 249. issue 2. 1999-07-02. PMID:10366428. |
fas antigen modulates ultraviolet b-induced apoptosis of svhk cells: sequential activation of caspases 8, 3, and 1 in the apoptotic process. |
1999-07-02 |
2023-08-12 |
human |
| H Takahashi, S Nakamura, K Asano, M Kinouchi, A Ishida-Yamamoto, H Iizuk. Fas antigen modulates ultraviolet B-induced apoptosis of SVHK cells: sequential activation of caspases 8, 3, and 1 in the apoptotic process. Experimental cell research. vol 249. issue 2. 1999-07-02. PMID:10366428. |
pretreatment of svhk cells with ifn-gamma significantly augmented uvb-induced apoptosis that was accompanied by increased fas expression. |
1999-07-02 |
2023-08-12 |
human |
| H Takahashi, S Nakamura, K Asano, M Kinouchi, A Ishida-Yamamoto, H Iizuk. Fas antigen modulates ultraviolet B-induced apoptosis of SVHK cells: sequential activation of caspases 8, 3, and 1 in the apoptotic process. Experimental cell research. vol 249. issue 2. 1999-07-02. PMID:10366428. |
our results suggest that uvb directly activates fas and subsequent caspase cascade resulting in apoptosis of svhk cells. |
1999-07-02 |
2023-08-12 |
human |
| H Takahashi, S Nakamura, K Asano, M Kinouchi, A Ishida-Yamamoto, H Iizuk. Fas antigen modulates ultraviolet B-induced apoptosis of SVHK cells: sequential activation of caspases 8, 3, and 1 in the apoptotic process. Experimental cell research. vol 249. issue 2. 1999-07-02. PMID:10366428. |
furthermore, the expression level of fas antigen in keratinocytes influenced their susceptibility to uvb-induced apoptosis. |
1999-07-02 |
2023-08-12 |
human |
| S W Kauma, T F Huff, N Hayes, A Nilkae. Placental Fas ligand expression is a mechanism for maternal immune tolerance to the fetus. The Journal of clinical endocrinology and metabolism. vol 84. issue 6. 1999-07-02. PMID:10372730. |
immunotolerance is achieved by binding of fasl to its receptor (fas) on activated immune cells, which results in cell apoptosis. |
1999-07-02 |
2023-08-12 |
human |
| S W Kauma, T F Huff, N Hayes, A Nilkae. Placental Fas ligand expression is a mechanism for maternal immune tolerance to the fetus. The Journal of clinical endocrinology and metabolism. vol 84. issue 6. 1999-07-02. PMID:10372730. |
when isolated peripheral blood lymphocytes were induced to express fas with phytohemagglutinin (pha) and interleukin-2 (il-2) and then cocultured with trophoblast, 30% of the lymphocytes underwent apoptosis, as determined by the in situ death (tunel) assay. |
1999-07-02 |
2023-08-12 |
human |
| E J Jeong, S Bang, T H Lee, Y I Park, W S Sim, K S Ki. The solution structure of FADD death domain. Structural basis of death domain interactions of Fas and FADD. The Journal of biological chemistry. vol 274. issue 23. 1999-07-01. PMID:10347191. |
a signal of fas-mediated apoptosis is transferred through an adaptor protein fas-associated death domain protein (fadd) by interactions between the death domains of fas and fadd. |
1999-07-01 |
2023-08-12 |
Not clear |
| K Fassbender, C Eschenfelder, M Henneric. Fas (APO-1/CD95) in inflammatory CNS diseases: intrathecal release in bacterial meningitis. Journal of neuroimmunology. vol 93. issue 1-2. 1999-07-01. PMID:10378875. |
release of fas (apo-1, cd95), a type l-membrane protein which plays a crucial role in cytokine-mediated apoptosis was investigated in bacterial meningitis, viral meningoencephalitis and multiple sclerosis in vivo. |
1999-07-01 |
2023-08-12 |
Not clear |
| E Sprecher, R Bergman, A Meilick, H Kerner, L Manov, I Reiter, Y Shafer, G Maor, R Friedman-Birnbau. Apoptosis, Fas and Fas-ligand expression in melanocytic tumors. Journal of cutaneous pathology. vol 26. issue 2. 1999-06-30. PMID:10082396. |
apoptosis, fas and fas-ligand expression in melanocytic tumors. |
1999-06-30 |
2023-08-12 |
Not clear |
| E Sprecher, R Bergman, A Meilick, H Kerner, L Manov, I Reiter, Y Shafer, G Maor, R Friedman-Birnbau. Apoptosis, Fas and Fas-ligand expression in melanocytic tumors. Journal of cutaneous pathology. vol 26. issue 2. 1999-06-30. PMID:10082396. |
fas binding to its ligand, fas ligand (fas-l), has been shown to trigger apoptosis in various cell types. |
1999-06-30 |
2023-08-12 |
Not clear |
| R D Pettersen, K Hestdal, M K Olafsen, S O Lie, F P Lindber. CD47 signals T cell death. Journal of immunology (Baltimore, Md. : 1950). vol 162. issue 12. 1999-06-30. PMID:10358145. |
activation-induced death of t cells regulates immune responses and is considered to involve apoptosis induced by ligation of fas and tnf receptors. |
1999-06-30 |
2023-08-12 |
Not clear |