| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Y G Ko, J S Lee, Y S Kang, J H Ahn, J S Se. TNF-alpha-mediated apoptosis is initiated in caveolae-like domains. Journal of immunology (Baltimore, Md. : 1950). vol 162. issue 12. 1999-06-30. PMID:10358168. |
since fas was not found in clds of jurkat cells, apoptosis by fas ligation might not require clds. |
1999-06-30 |
2023-08-12 |
Not clear |
| H Yamashita, Y Otsuki, K Matsumoto, K Ueki, M Uek. Fas ligand, Fas antigen and Bcl-2 expression in human endometrium during the menstrual cycle. Molecular human reproduction. vol 5. issue 4. 1999-06-29. PMID:10321808. |
the factors regulating fas-mediated apoptosis in the human endometrium, including the level of expression of the fas ligand and bcl-2 are discussed. |
1999-06-29 |
2023-08-12 |
human |
| C Y Chen, D V Falle. Selective inhibition of protein kinase C isozymes by Fas ligation. The Journal of biological chemistry. vol 274. issue 22. 1999-06-29. PMID:10336417. |
activation of protein kinase c (pkc) can protect cells from apoptosis induced by various agents, including fas ligation. |
1999-06-29 |
2023-08-12 |
mouse |
| C Y Chen, D V Falle. Selective inhibition of protein kinase C isozymes by Fas ligation. The Journal of biological chemistry. vol 274. issue 22. 1999-06-29. PMID:10336417. |
we demonstrate that engagement of fas on human lymphoid jurkat cells triggered apoptosis, and fas ligation resulted in partial blockade of cellular pkc activity. |
1999-06-29 |
2023-08-12 |
mouse |
| S Yamamoto, M Mogi, K Kinpara, Y Ishihara, N Ueda, K Amano, T Nishihara, T Noguchi, A Togar. Anti-proliferative capsular-like polysaccharide antigen from Actinobacillus actinomycetemcomitans induces apoptotic cell death in mouse osteoblastic MC3T3-E1 cells. Journal of dental research. vol 78. issue 6. 1999-06-29. PMID:10371246. |
therefore, this study has shown that cpa from a. actinomycetemcomitans contains a potent antiproliferative polysaccharide whose activity is associated with apoptotic cell death in mc3t3-e1, and that cpa per se is an inducer of apoptosis mediated by the fas system but not by no. |
1999-06-29 |
2023-08-12 |
mouse |
| M K Chen, L F Strande, E A Beierle, M S Kain, B D Geldziler, E J Dooli. Fas-mediated induction of hepatocyte apoptosis in a neuroblastoma and hepatocyte coculture model. The Journal of surgical research. vol 84. issue 1. 1999-06-28. PMID:10334894. |
death receptors in the tumor necrosis factor (tnf) family such as tnfr1 and fas have been identified as regulators of apoptosis and may be responsible for the altered regulation of apoptosis seen in our coculture model. |
1999-06-28 |
2023-08-12 |
Not clear |
| L Peduto Eberl, L Guillou, E Saraga, M Schröter, L E French, J Tschopp, L Juillerat-Jeannere. Fas and Fas ligand expression in tumor cells and in vascular smooth-muscle cells of colonic and renal carcinomas. International journal of cancer. vol 81. issue 5. 1999-06-25. PMID:10328232. |
the 2 cell lines expressed the same level of fas, but were resistant to fasl-induced apoptosis. |
1999-06-25 |
2023-08-12 |
human |
| T Kobayashi, K Okamoto, T Kobata, T Hasumuna, K Nishiok. Apomodulation as a novel therapeutic concept for the regulation of apoptosis in rheumatoid synoviocytes. Current opinion in rheumatology. vol 11. issue 3. 1999-06-25. PMID:10328578. |
employing these molecular processes in the treatment of ra, we have recently shown that ex vivo gene transfer of human fas ligand (hfasl) induced apoptosis of synoviocytes and infiltrated mononuclear cells of ra synovial tissue through cell-to-cell interaction via the fas/fasl system. |
1999-06-25 |
2023-08-12 |
human |
| J P Weintraub, P L Cohe. Ectopic expression of B7-1 (CD80) on T lymphocytes in autoimmune lpr and gld mice. Clinical immunology (Orlando, Fla.). vol 91. issue 3. 1999-06-25. PMID:10370375. |
defective fas-mediated apoptosis in mice, caused by the gld mutation in the fas ligand gene, results in the development of lupus-like autoantibodies and severe lymphoproliferation. |
1999-06-25 |
2023-08-12 |
mouse |
| M Hishii, J T Kurnick, T Ramirez-Montagut, F Pandolf. Studies of the mechanism of cytolysis by tumour-infiltrating lymphocytes. Clinical and experimental immunology. vol 116. issue 3. 1999-06-23. PMID:10361224. |
the glioma, and all but one of the melanomas, expressed fas, but fas-mediated apoptosis could only be detected if the targets were treated with cyclohexamide. |
1999-06-23 |
2023-08-12 |
Not clear |
| W Zhou, D Zhang, X Ji. [Apoptosis in MT2 cells induced by HepG2.2.15 cells]. Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology. vol 7. issue 1. 1999-06-23. PMID:10366984. |
to obtain the apoptosis in mt2 cells induced by hepg2.2.15 cells expressing fas ligand. |
1999-06-23 |
2023-08-12 |
Not clear |
| K Nakashima, K Yamashita, S Uesugi, H It. Temporal and spatial profile of apoptotic cell death in transient intracerebral mass lesion of the rat. Journal of neurotrauma. vol 16. issue 2. 1999-06-22. PMID:10098959. |
immunohistochemistry for fas antigen was also done to ascertain molecular mechanisms of apoptosis. |
1999-06-22 |
2023-08-12 |
rat |
| L A Trimble, Z Xu, J Lieberma. Clonal expansion of antigen-specific CD8+ cytotoxic T lymphocytes is regulated by late exposure to serum to prevent apoptosis. Journal of immunological methods. vol 225. issue 1-2. 1999-06-22. PMID:10365780. |
apoptosis of tcr-activated ctl does not appear to be fas-mediated since it is not blocked by inhibiting the fas pathway. |
1999-06-22 |
2023-08-12 |
Not clear |
| V N Ivanov, Z Rona. Down-regulation of tumor necrosis factor alpha expression by activating transcription factor 2 increases UVC-induced apoptosis of late-stage melanoma cells. The Journal of biological chemistry. vol 274. issue 20. 1999-06-17. PMID:10318823. |
antagonistic antibodies to fas, but not to tnfr1, efficiently suppressed uvc-induced apoptosis, suggesting that the fas pathway mediates the primary apoptotic signal in melanoma cells whereas the tnfr1 pathway elicits a survival signal. |
1999-06-17 |
2023-08-12 |
human |
| Y Hiromatsu, T Bednarczuk, E Soyejima, I Miyake, D Yang, H Fukazawa, K Nonak. Increased serum soluble Fas in patients with Graves' disease. Thyroid : official journal of the American Thyroid Association. vol 9. issue 4. 1999-06-17. PMID:10319938. |
we addressed the role of soluble fas (sfas), which suppresses fas-mediated apoptosis, in the pathogenesis of graves' disease (gd). |
1999-06-17 |
2023-08-12 |
human |
| M V Kat. The mechanisms of death of an erythroleukemic cell line by p53: involvement of the microtubule and mitochondria. Leukemia & lymphoma. vol 33. issue 1-2. 1999-06-16. PMID:10194136. |
however, no significant changes were detected in the expression of the mdm2, bcl-2, bax, fas and fasl genes, suggesting the existence of other genes associated with apoptosis. |
1999-06-16 |
2023-08-12 |
human |
| R Agarwal, M Talati, W Lambert, A F Clark, S E Wilson, N Agarwal, R J Wordinge. Fas-activated apoptosis and apoptosis mediators in human trabecular meshwork cells. Experimental eye research. vol 68. issue 5. 1999-06-16. PMID:10328972. |
using rt-pcr it was shown that mrna for several modulators of apoptosis (fas, bcl-2, bcl-xl, bax, and ice) are expressed by both cell lines and ex-vivo tissues. |
1999-06-16 |
2023-08-12 |
human |
| R Agarwal, M Talati, W Lambert, A F Clark, S E Wilson, N Agarwal, R J Wordinge. Fas-activated apoptosis and apoptosis mediators in human trabecular meshwork cells. Experimental eye research. vol 68. issue 5. 1999-06-16. PMID:10328972. |
apoptosis was stimulated to occur by treating cell lines with a monoclonal antibody (igm) to fas. |
1999-06-16 |
2023-08-12 |
human |
| J Zhang, A K Somani, S Watt, G B Mills, K A Siminovitc. The Src-homology domain 2-bearing protein tyrosine phosphatase-1 inhibits antigen receptor-induced apoptosis of activated peripheral T cells. Journal of immunology (Baltimore, Md. : 1950). vol 162. issue 11. 1999-06-16. PMID:10352248. |
enhanced apoptosis of tcr-restimulated mev lymphocytes was associated with marked increases in fas ligand expression as compared with wild-type cells, but was almost abrogated in both mev and wild-type cells by fas-fc treatment. |
1999-06-16 |
2023-08-12 |
mouse |
| J Zhang, A K Somani, S Watt, G B Mills, K A Siminovitc. The Src-homology domain 2-bearing protein tyrosine phosphatase-1 inhibits antigen receptor-induced apoptosis of activated peripheral T cells. Journal of immunology (Baltimore, Md. : 1950). vol 162. issue 11. 1999-06-16. PMID:10352248. |
thus, the increased sensitivity of mev t cells to apoptosis following tcr restimulation appears to reflect a tcr-driven phenomenon mediated through up-regulation of fas-fas ligand interaction and induction of the fas signaling cascade. |
1999-06-16 |
2023-08-12 |
mouse |