| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Y Refaeli, A K Abba. Role of cytokines in autoimmunity. European cytokine network. vol 9. issue 3 Suppl. 1999-06-15. PMID:9831192. |
the sensitivity of t cells to apoptosis by the fas pathway is regulated by the exposure of these cells to different cytokines. |
1999-06-15 |
2023-08-12 |
Not clear |
| T Takizawa, C Tatematsu, Y Nakanish. Double-stranded RNA-activated protein kinase (PKR) fused to green fluorescent protein induces apoptosis of human embryonic kidney cells: possible role in the Fas signaling pathway. Journal of biochemistry. vol 125. issue 2. 1999-06-15. PMID:9990139. |
double-stranded rna-activated protein kinase (pkr) fused to green fluorescent protein induces apoptosis of human embryonic kidney cells: possible role in the fas signaling pathway. |
1999-06-15 |
2023-08-12 |
human |
| M R Wilso. Apoptotic signal transduction: emerging pathways. Biochemistry and cell biology = Biochimie et biologie cellulaire. vol 76. issue 4. 1999-06-15. PMID:10099777. |
in addition, the mechanism by which the cell surface fas receptor mediates induction of apoptosis, via activation of caspases, has recently been elucidated. |
1999-06-15 |
2023-08-12 |
caenorhabditis_elegans |
| H J Garbán, B Bonavid. Nitric oxide sensitizes ovarian tumor cells to Fas-induced apoptosis. Gynecologic oncology. vol 73. issue 2. 1999-06-14. PMID:10329044. |
in this study, we examined whether nitric oxide is a mediator of ifn-gamma-induced sensitization of human ovarian carcinoma cell lines (a2780 and ad10) to fas-mediated apoptosis and whether no regulates the expression of the fas receptor. |
1999-06-14 |
2023-08-12 |
human |
| H J Garbán, B Bonavid. Nitric oxide sensitizes ovarian tumor cells to Fas-induced apoptosis. Gynecologic oncology. vol 73. issue 2. 1999-06-14. PMID:10329044. |
these findings demonstrate that sensitization of human ovarian carcinoma cell lines to fas-mediated apoptosis by ifn-gamma can be due, in part, to the induction of inos and the subsequent upregulation of fas gene expression by reactive nitrogen intermediates. |
1999-06-14 |
2023-08-12 |
human |
| P Herse. Impediments to successful immunotherapy. Pharmacology & therapeutics. vol 81. issue 2. 1999-06-11. PMID:10190582. |
tumor cells may also become resistant to mediators of apoptosis, such as fas ligand and tumor necrosis factor-related apoptosis-inducing ligand used by lymphocytes to kill tumor cells. |
1999-06-11 |
2023-08-12 |
Not clear |
| S Sainio-Pöllänen, A Liukas, P Pöllänen, O Simel. The role of CD8+ cells, cell degeneration, and Fas ligand in insulitis after intraperitoneal transfer of NOD splenocytes. Pancreas. vol 18. issue 3. 1999-06-11. PMID:10206487. |
it is proposed that apoptosis commonly occurs in islet-infiltrating lymphocytes and that in the scid/scid adoptive-transfer model, the first islet-infiltrating cells are destroyed by programmed cell death independent of fas ligand. |
1999-06-11 |
2023-08-12 |
mouse |
| B Wedi, U Raap, A Kap. Significant delay of apoptosis and Fas resistance in eosinophils of subjects with intrinsic and extrinsic type of atopic dermatitis. International archives of allergy and immunology. vol 118. issue 2-4. 1999-06-10. PMID:10224394. |
significant delay of apoptosis and fas resistance in eosinophils of subjects with intrinsic and extrinsic type of atopic dermatitis. |
1999-06-10 |
2023-08-12 |
human |
| C Dai, S B Krant. Interferon gamma induces upregulation and activation of caspases 1, 3, and 8 to produce apoptosis in human erythroid progenitor cells. Blood. vol 93. issue 10. 1999-06-10. PMID:10233883. |
fas (apo-1; cd95) and fas ligand (fasl) mediate apoptosis induced by ifngamma, because fas is significantly upregulated by ifngamma, whereas fas ligand is constitutively present in the ecfc and neutralization of fasl greatly reduces the apoptosis. |
1999-06-10 |
2023-08-12 |
human |
| C Dai, S B Krant. Interferon gamma induces upregulation and activation of caspases 1, 3, and 8 to produce apoptosis in human erythroid progenitor cells. Blood. vol 93. issue 10. 1999-06-10. PMID:10233883. |
these results indicate that ifngamma acts on ecfc not only to upregulate fas, but also to selectively upregulate caspases-1, -3, and -8, which are activated and produce apoptosis, whereas the concentrations of fasl and fadd are not demonstrably changed. |
1999-06-10 |
2023-08-12 |
human |
| G A Pestano, Y Zhou, L A Trimble, J Daley, G F Weber, H Canto. Inactivation of misselected CD8 T cells by CD8 gene methylation and cell death. Science (New York, N.Y.). vol 284. issue 5417. 1999-06-08. PMID:10325233. |
the failure of mature cd8 cells to simultaneously engage their tcr and cd8 coreceptor triggers an activation process that begins with inhibition of cd8 gene expression through remethylation and concludes with up-regulation of surface fas and fas ligand and cellular apoptosis. |
1999-06-08 |
2023-08-12 |
Not clear |
| R M Siegel, T A Fleishe. The role of Fas and related death receptors in autoimmune and other disease states. The Journal of allergy and clinical immunology. vol 103. issue 5 Pt 1. 1999-06-08. PMID:10329802. |
t cells can also trigger apoptosis in b cells, macrophages, and other cell types through fas ligand. |
1999-06-08 |
2023-08-12 |
mouse |
| T Yamamura, H Nakamura, T Yamamoto, S Umemoto, T Fujii, N Kobayashi, M Matsuzak. Fas expression and apoptosis correlate with cardiac dysfunction in patients with dilated cardiomyopathy. Japanese circulation journal. vol 63. issue 3. 1999-06-07. PMID:10201613. |
fas expression and apoptosis correlate with cardiac dysfunction in patients with dilated cardiomyopathy. |
1999-06-07 |
2023-08-12 |
human |
| T Yamamura, H Nakamura, T Yamamoto, S Umemoto, T Fujii, N Kobayashi, M Matsuzak. Fas expression and apoptosis correlate with cardiac dysfunction in patients with dilated cardiomyopathy. Japanese circulation journal. vol 63. issue 3. 1999-06-07. PMID:10201613. |
fas is a transmembranous glycoprotein that mediates apoptosis. |
1999-06-07 |
2023-08-12 |
human |
| T Yamamura, H Nakamura, T Yamamoto, S Umemoto, T Fujii, N Kobayashi, M Matsuzak. Fas expression and apoptosis correlate with cardiac dysfunction in patients with dilated cardiomyopathy. Japanese circulation journal. vol 63. issue 3. 1999-06-07. PMID:10201613. |
to elucidate the roles of fas and of myocyte apoptosis in patients with dilated cardiomyopathy (dcm), the expression of fas and the fragmentation of dna were compared in endomyocardial biopsy specimens obtained from patients with dcm. |
1999-06-07 |
2023-08-12 |
human |
| T Yamamura, H Nakamura, T Yamamoto, S Umemoto, T Fujii, N Kobayashi, M Matsuzak. Fas expression and apoptosis correlate with cardiac dysfunction in patients with dilated cardiomyopathy. Japanese circulation journal. vol 63. issue 3. 1999-06-07. PMID:10201613. |
these results suggest that fas expression and apoptosis may be involved in the progression of cardiac dysfunction in dcm. |
1999-06-07 |
2023-08-12 |
human |
| A N Liu, A Z Mohammed, W R Rice, D T Fiedeldey, J S Liebermann, J A Whitsett, T J Braciale, R I Enelo. Perforin-independent CD8(+) T-cell-mediated cytotoxicity of alveolar epithelial cells is preferentially mediated by tumor necrosis factor-alpha: relative insensitivity to Fas ligand. American journal of respiratory cell and molecular biology. vol 20. issue 5. 1999-06-07. PMID:10226053. |
the primary effector function of this t-cell subset is cytolysis of virus-infected cells, and it is widely believed that there are two primary molecular mechanisms by which this occurs: the perforin/granzyme-mediated pathway of cytolysis, and the fas ligand (fasl)-fas (cd95/apo-1) pathway of induction of target-cell apoptosis. |
1999-06-07 |
2023-08-12 |
mouse |
| A N Liu, A Z Mohammed, W R Rice, D T Fiedeldey, J S Liebermann, J A Whitsett, T J Braciale, R I Enelo. Perforin-independent CD8(+) T-cell-mediated cytotoxicity of alveolar epithelial cells is preferentially mediated by tumor necrosis factor-alpha: relative insensitivity to Fas ligand. American journal of respiratory cell and molecular biology. vol 20. issue 5. 1999-06-07. PMID:10226053. |
we present evidence that fasl-induced, fas-mediated apoptosis does not directly contribute to t-cell-mediated cytolysis of alveolar epithelial-derived cells, even though fas is expressed and functional on these cells. |
1999-06-07 |
2023-08-12 |
mouse |
| D Li, K Tomson, B Yang, P Mehta, B P Croker, J L Meht. Modulation of constitutive nitric oxide synthase, bcl-2 and Fas expression in cultured human coronary endothelial cells exposed to anoxia-reoxygenation and angiotensin II: role of AT1 receptor activation. Cardiovascular research. vol 41. issue 1. 1999-06-03. PMID:10325958. |
recent studies suggest an important role of constitutive nitric oxide synthase (cnos), fas and bcl-2 proteins in apoptosis. |
1999-06-03 |
2023-08-12 |
human |
| R Bachmann, H P Eugster, K Frei, A Fontana, H Lassman. Impairment of TNF-receptor-1 signaling but not fas signaling diminishes T-cell apoptosis in myelin oligodendrocyte glycoprotein peptide-induced chronic demyelinating autoimmune encephalomyelitis in mice. The American journal of pathology. vol 154. issue 5. 1999-06-03. PMID:10329594. |
impairment of tnf-receptor-1 signaling but not fas signaling diminishes t-cell apoptosis in myelin oligodendrocyte glycoprotein peptide-induced chronic demyelinating autoimmune encephalomyelitis in mice. |
1999-06-03 |
2023-08-12 |
mouse |