| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| T J Moran, S Gray, C A Mikosz, S D Conze. The glucocorticoid receptor mediates a survival signal in human mammary epithelial cells. Cancer research. vol 60. issue 4. 2000-03-20. PMID:10706096. |
although mcf10a cells can undergo apoptosis after cd95/fas receptor activation, cell death caused by glucocorticoid withdrawal is independent of cd95/ fas receptor signaling. |
2000-03-20 |
2023-08-12 |
human |
| K Reich, U Brinck, M Letschert, V Blaschke, K Dames, J Braess, B Wörmann, T M Rünger, C Neuman. Graft-versus-host disease-like immunophenotype and apoptotic keratinocyte death in paraneoplastic pemphigus. The British journal of dermatology. vol 141. issue 4. 2000-03-16. PMID:10583130. |
apoptosis was identified as a key mechanism of keratinocyte death, and appeared independent of the fas/fas ligand (fas-l) pathway, as epidermal expression of fas was not increased compared with normal skin, and fas-l was undetectable on the protein and mrna level. |
2000-03-16 |
2023-08-12 |
Not clear |
| D Munsch, R Watanabe-Fukunaga, J C Bourdon, S Nagata, E May, E Yonish-Rouach, P Reisdor. Human and mouse Fas (APO-1/CD95) death receptor genes each contain a p53-responsive element that is activated by p53 mutants unable to induce apoptosis. The Journal of biological chemistry. vol 275. issue 6. 2000-03-16. PMID:10660538. |
human and mouse fas (apo-1/cd95) death receptor genes each contain a p53-responsive element that is activated by p53 mutants unable to induce apoptosis. |
2000-03-16 |
2023-08-12 |
mouse |
| D Munsch, R Watanabe-Fukunaga, J C Bourdon, S Nagata, E May, E Yonish-Rouach, P Reisdor. Human and mouse Fas (APO-1/CD95) death receptor genes each contain a p53-responsive element that is activated by p53 mutants unable to induce apoptosis. The Journal of biological chemistry. vol 275. issue 6. 2000-03-16. PMID:10660538. |
contrary to bax, another known pro-apoptotic p53-target gene, both mouse and human fas p53res are still activated by the discriminatory p53 mutants pro-175 and ala-143, a class of mutants unable to induce apoptosis. |
2000-03-16 |
2023-08-12 |
mouse |
| D Munsch, R Watanabe-Fukunaga, J C Bourdon, S Nagata, E May, E Yonish-Rouach, P Reisdor. Human and mouse Fas (APO-1/CD95) death receptor genes each contain a p53-responsive element that is activated by p53 mutants unable to induce apoptosis. The Journal of biological chemistry. vol 275. issue 6. 2000-03-16. PMID:10660538. |
we propose that p53-dependent up-regulation of fas does not induce apoptosis per se but sensitizes the cell to other pro-apoptotic signal(s). |
2000-03-16 |
2023-08-12 |
mouse |
| J Houghton, L S Macera-Bloch, L Harrison, K H Kim, R M Kora. Tumor necrosis factor alpha and interleukin 1beta up-regulate gastric mucosal Fas antigen expression in Helicobacter pylori infection. Infection and immunity. vol 68. issue 3. 2000-03-16. PMID:10678925. |
taken together, these data indicate that the immune environment secondary to h. pylori infection plays a critical role in priming gastric mucosal cells to undergo apoptosis or to proliferate based upon their fas ag status. |
2000-03-16 |
2023-08-12 |
Not clear |
| T Yoshino, H Asada, S Sano, T Nakamura, S Itami, M Tamura, K Yoshikaw. Impaired responses of peripheral blood mononuclear cells to staphylococcal superantigen in patients with severe atopic dermatitis: a role of T cell apoptosis. The Journal of investigative dermatology. vol 114. issue 2. 2000-03-15. PMID:10651987. |
blocking monoclonal antibody to fas ligand partially prevented the staphylococcal-enterotoxin-b-induced apoptosis detected by apo2.7 expression and hoechst 33258 staining. |
2000-03-15 |
2023-08-12 |
Not clear |
| S Nagat. Fas ligand-induced apoptosis. Annual review of genetics. vol 33. 2000-03-15. PMID:10690403. |
fas ligand-induced apoptosis. |
2000-03-15 |
2023-08-12 |
mouse |
| Z X Liu, S Govindarajan, S Okamoto, G Denner. Fas- and tumor necrosis factor receptor 1-dependent but not perforin-dependent pathways cause injury in livers infected with an adenovirus construct in mice. Hepatology (Baltimore, Md.). vol 31. issue 3. 2000-03-15. PMID:10706557. |
making use of mice in which the genes coding for fas, fasl, tnf receptors (tnfrs), and perforin are inactivated, as well as recombinant proteins that inhibit fas- and tnf-alpha-mediated apoptosis, it is shown that a functional perforin-mediated mechanism is not obligatory for cellular infiltration and progression of liver injury. |
2000-03-15 |
2023-08-12 |
mouse |
| S Jiang, M W Wu, P Sternberg, D P Jone. Fas mediates apoptosis and oxidant-induced cell death in cultured hRPE cells. Investigative ophthalmology & visual science. vol 41. issue 3. 2000-03-15. PMID:10711676. |
fas mediates apoptosis and oxidant-induced cell death in cultured hrpe cells. |
2000-03-15 |
2023-08-12 |
human |
| S Jiang, M W Wu, P Sternberg, D P Jone. Fas mediates apoptosis and oxidant-induced cell death in cultured hRPE cells. Investigative ophthalmology & visual science. vol 41. issue 3. 2000-03-15. PMID:10711676. |
to investigate whether fas ligand (fasl) and the fas receptor system mediates apoptosis in cultured human retinal pigment epithelial (hrpe) cells and contributes to oxidant-induced death of hrpe cells. |
2000-03-15 |
2023-08-12 |
human |
| J Sueda, N Hikita, M Mochizuki, A Jimi, M Kojir. Kinetics of apoptotic cells in experimental autoimmune uveoretinitis. Investigative ophthalmology & visual science. vol 41. issue 3. 2000-03-15. PMID:10711696. |
to investigate the role of apoptosis in immunopathogenic mechanisms of experimental autoimmune uveoretinitis (eau), the kinetics of apoptotic cells and expression of fas and fas ligand (fasl) in the eye with eau were studied. |
2000-03-15 |
2023-08-12 |
Not clear |
| M Li-Weber, O Laur, K Dern, P H Kramme. T cell activation-induced and HIV tat-enhanced CD95(APO-1/Fas) ligand transcription involves NF-kappaB. European journal of immunology. vol 30. issue 2. 2000-03-14. PMID:10671224. |
cd95(apo-1 / fas) ligand (cd95l) gene expression is critically involved in activation-induced t cell apoptosis. |
2000-03-14 |
2023-08-12 |
human |
| E Kuranaga, H Kanuka, K Hirabayashi, M Suzuki, M Nishihara, M Takahash. Progesterone is a cell death suppressor that downregulates Fas expression in rat corpus luteum. FEBS letters. vol 466. issue 2-3. 2000-03-14. PMID:10682843. |
these data indicate that p4 suppresses prl-induced luteal cell apoptosis via reduction of the expression level of fas mrna in the corpus luteum, suggesting that p4 acts as an important factor that can change the sensitivity of corpus luteum to prl. |
2000-03-14 |
2023-08-12 |
rat |
| H Koizumi, I Ohkawa, T Tsukahara, T Momoi, K Nakada, T Uchikosh. Apoptosis in favourable neuroblastomas is not dependent on Fas (CD95/APO-1) expression but on activated caspase 3 (CPP32). The Journal of pathology. vol 189. issue 3. 2000-03-13. PMID:10547604. |
apoptosis in favourable neuroblastomas is not dependent on fas (cd95/apo-1) expression but on activated caspase 3 (cpp32). |
2000-03-13 |
2023-08-12 |
Not clear |
| H Koizumi, I Ohkawa, T Tsukahara, T Momoi, K Nakada, T Uchikosh. Apoptosis in favourable neuroblastomas is not dependent on Fas (CD95/APO-1) expression but on activated caspase 3 (CPP32). The Journal of pathology. vol 189. issue 3. 2000-03-13. PMID:10547604. |
the mechanisms of apoptosis in neuroblastomas have been investigated by examining the expression profiles of fas, fas ligand (fasl), and caspase 3 in 42 primary tumour tissues. |
2000-03-13 |
2023-08-12 |
Not clear |
| M Kornmann, T Ishiwata, H Maruyama, H G Beger, M Kor. Coexpression of FAS and FAS-ligand in chronic pancreatitis: correlation with apoptosis. Pancreas. vol 20. issue 2. 2000-03-13. PMID:10707926. |
coexpression of fas and fas-ligand in chronic pancreatitis: correlation with apoptosis. |
2000-03-13 |
2023-08-12 |
Not clear |
| M Kornmann, T Ishiwata, H Maruyama, H G Beger, M Kor. Coexpression of FAS and FAS-ligand in chronic pancreatitis: correlation with apoptosis. Pancreas. vol 20. issue 2. 2000-03-13. PMID:10707926. |
activation of the fas receptor by fas-ligand (fasl) results in apoptosis, and dysregulation of this pathway may contribute to abnormal cell proliferation and cell death. |
2000-03-13 |
2023-08-12 |
Not clear |
| M Kornmann, T Ishiwata, H Maruyama, H G Beger, M Kor. Coexpression of FAS and FAS-ligand in chronic pancreatitis: correlation with apoptosis. Pancreas. vol 20. issue 2. 2000-03-13. PMID:10707926. |
these findings suggest that activation of apoptosis through the fas receptor may contribute to the pathobiology of cp. |
2000-03-13 |
2023-08-12 |
Not clear |
| T Kawamura, M Azuma, N Kayagaki, S Shimada, H Yagita, K Okumur. Fas/Fas ligand-mediated apoptosis of murine Langerhans cells. Journal of dermatological science. vol 22. issue 2. 2000-03-10. PMID:10674822. |
interestingly, epidermal lc underwent apoptosis by the addition of both recombinant soluble fas ligand (fasl) and ifn-gamma, but not by fasl alone. |
2000-03-10 |
2023-08-12 |
Not clear |