| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| T Kawamura, M Azuma, N Kayagaki, S Shimada, H Yagita, K Okumur. Fas/Fas ligand-mediated apoptosis of murine Langerhans cells. Journal of dermatological science. vol 22. issue 2. 2000-03-10. PMID:10674822. |
these results suggest that lc may acquire the susceptibility to fas-mediated apoptosis through up-regulation of the fas expression by ifn-gamma derived from activated t cells and that the elimination of lc may be important for preventing excess cutaneous inflammatory diseases. |
2000-03-10 |
2023-08-12 |
Not clear |
| S H Lee, M S Shin, H S Kim, W S Park, S Y Kim, J J Jang, K J Rhim, J Jang, H K Lee, J Y Park, R R Oh, S Y Han, J H Lee, J Y Lee, N J Yo. Somatic mutations of Fas (Apo-1/CD95) gene in cutaneous squamous cell carcinoma arising from a burn scar. The Journal of investigative dermatology. vol 114. issue 1. 2000-03-09. PMID:10620127. |
our data show that some burn scar-related squamous cell carcinomas have fas gene mutations in important regions for the apoptosis function and suggest that these mutations might be involved in the pathogenesis of burn scar-related squamous cell carcinomas. |
2000-03-09 |
2023-08-12 |
human |
| b' J A Guevara Pati\\xc3\\xb1o, V N Ivanov, E Lacy, K B Elkon, M W Marino, J Nikolic-Zugi\\xc4\\x8. TNF-alpha is the critical mediator of the cyclic AMP-induced apoptosis of CD8+4+ double-positive thymocytes. Journal of immunology (Baltimore, Md. : 1950). vol 164. issue 4. 2000-03-09. PMID:10657611.' |
we studied the possible role of two prominent nerve growth factor (ngf-tnf) family member systems, fas ligand (fasl)-fas receptor (fasr) and tnf-alpha-tnfr, in apoptosis of murine cd8+4+ double-positive (dp) thymocytes induced via tcr-cd3- and camp-mediated signaling. |
2000-03-09 |
2023-08-12 |
Not clear |
| K Kühn, S Hashimoto, M Lot. IL-1 beta protects human chondrocytes from CD95-induced apoptosis. Journal of immunology (Baltimore, Md. : 1950). vol 164. issue 4. 2000-03-09. PMID:10657679. |
this study addresses the effects of il-1 beta on apoptosis induced by agonistic anti-cd95 (fas) ab. |
2000-03-09 |
2023-08-12 |
human |
| S Takamizawa, S Okamoto, J Wen, W Bishop, K Kimura, A Sandle. Overexpression of Fas-ligand by neuroblastoma: a novel mechanism of tumor-cell killing. Journal of pediatric surgery. vol 35. issue 2. 2000-03-09. PMID:10693700. |
binding of fas ligand (fas-l) to the membrane-bound fas receptor incites a series of intracellular events that results in programmed cell death or apoptosis. |
2000-03-09 |
2023-08-12 |
Not clear |
| C Y Chu, J Tsen. Induction of Fas and Fas-ligand expression in plasmacytoma cells by a cytotoxic factor secreted by murine macrophages. Journal of biomedical science. vol 7. issue 1. 2000-03-08. PMID:10644890. |
in this report, the involvement of fas and fas ligand (fasl) in pcf-induced apoptosis was investigated. |
2000-03-08 |
2023-08-12 |
Not clear |
| C Y Chu, J Tsen. Induction of Fas and Fas-ligand expression in plasmacytoma cells by a cytotoxic factor secreted by murine macrophages. Journal of biomedical science. vol 7. issue 1. 2000-03-08. PMID:10644890. |
therefore, pcf-treated plasmacytoma cells might undergo apoptosis via interaction between fas and fasl. |
2000-03-08 |
2023-08-12 |
Not clear |
| W Luttmann, E Dauer, S Schmidt, O Marx, M Hossfeld, H Matthys, J C Vircho. Effects of interferon-gamma and tumour necrosis factor-alpha on CD95/Fas ligand-mediated apoptosis in human blood eosinophils. Scandinavian journal of immunology. vol 51. issue 1. 2000-03-07. PMID:10632976. |
many cells, including eosinophils, express cd95 (fas), a surface receptor that mediates apoptosis when ligated by specific antibodies or its natural ligand, fas ligand (fasl). |
2000-03-07 |
2023-08-12 |
human |
| J Komi, O Lassil. Toremifene increases the expression of intercellular adhesion molecule-1 (ICAM-1) on MCF-7 breast cancer cells and Jurkat cells. Scandinavian journal of immunology. vol 51. issue 1. 2000-03-07. PMID:10632979. |
toremifene did not affect fas expression or fas-mediated apoptosis in fas-resistant mcf-7 or fas-sensitive jurkat cells, but was found to increase the expression of icam-1 in both cell lines. |
2000-03-07 |
2023-08-12 |
Not clear |
| U Felderhoff-Mueser, D L Taylor, K Greenwood, M Kozma, D Stibenz, U C Joashi, A D Edwards, H Mehme. Fas/CD95/APO-1 can function as a death receptor for neuronal cells in vitro and in vivo and is upregulated following cerebral hypoxic-ischemic injury to the developing rat brain. Brain pathology (Zurich, Switzerland). vol 10. issue 1. 2000-03-07. PMID:10668892. |
apoptosis is a major mechanism of neuronal loss following hypoxic-ischemic injury to the developing brain, although the role of fas in this process has not been studied in detail. |
2000-03-07 |
2023-08-12 |
rat |
| U Felderhoff-Mueser, D L Taylor, K Greenwood, M Kozma, D Stibenz, U C Joashi, A D Edwards, H Mehme. Fas/CD95/APO-1 can function as a death receptor for neuronal cells in vitro and in vivo and is upregulated following cerebral hypoxic-ischemic injury to the developing rat brain. Brain pathology (Zurich, Switzerland). vol 10. issue 1. 2000-03-07. PMID:10668892. |
cross-linking of fas induced neuronal apoptosis both in neuronal pc12 cells in culture and following intracerebral injection in vivo, indicating that neuronal fas was functional as a death receptor. |
2000-03-07 |
2023-08-12 |
rat |
| U Felderhoff-Mueser, D L Taylor, K Greenwood, M Kozma, D Stibenz, U C Joashi, A D Edwards, H Mehme. Fas/CD95/APO-1 can function as a death receptor for neuronal cells in vitro and in vivo and is upregulated following cerebral hypoxic-ischemic injury to the developing rat brain. Brain pathology (Zurich, Switzerland). vol 10. issue 1. 2000-03-07. PMID:10668892. |
these results suggest that fas may be involved in neuronal apoptosis following hypoxic-ischemic injury to the developing brain. |
2000-03-07 |
2023-08-12 |
rat |
| C S Seitz, R A Freiberg, K Hinata, P A Khavar. NF-kappaB determines localization and features of cell death in epidermis. The Journal of clinical investigation. vol 105. issue 3. 2000-03-06. PMID:10675350. |
here, we show that nf-kappab protects normal epithelial cells from apoptosis induced by both tnfalpha and fas, whereas nf-kappab blockade enhances susceptibility to death via both pathways. |
2000-03-06 |
2023-08-12 |
mouse |
| G Feng, N Kaplowit. Colchicine protects mice from the lethal effect of an agonistic anti-Fas antibody. The Journal of clinical investigation. vol 105. issue 3. 2000-03-06. PMID:10675359. |
in addition, colchicine pretreatment reduced surface expression of fas and decreased jo2- and tnf-alpha-induced apoptosis of cultured hepatocytes in the presence of actinomycin d, but did not affect the susceptibility of cultured sinusoidal endothelial cells to jo2-induced apoptosis. |
2000-03-06 |
2023-08-12 |
mouse |
| G Feng, N Kaplowit. Colchicine protects mice from the lethal effect of an agonistic anti-Fas antibody. The Journal of clinical investigation. vol 105. issue 3. 2000-03-06. PMID:10675359. |
remarkably, fas and tnf receptor-1 mrna and intracellular protein levels increased after colchicine treatment, indicating that colchicine protects against death ligand-induced apoptosis in the liver by decreasing death-receptor targeting to the cell surface. |
2000-03-06 |
2023-08-12 |
mouse |
| M Sata, T Suhara, K Wals. Vascular endothelial cells and smooth muscle cells differ in expression of Fas and Fas ligand and in sensitivity to Fas ligand-induced cell death: implications for vascular disease and therapy. Arteriosclerosis, thrombosis, and vascular biology. vol 20. issue 2. 2000-03-03. PMID:10669625. |
fas ligand (fasl) is a death factor that induces apoptosis in cells bearing its receptor, fas. |
2000-03-03 |
2023-08-12 |
human |
| M Sata, T Suhara, K Wals. Vascular endothelial cells and smooth muscle cells differ in expression of Fas and Fas ligand and in sensitivity to Fas ligand-induced cell death: implications for vascular disease and therapy. Arteriosclerosis, thrombosis, and vascular biology. vol 20. issue 2. 2000-03-03. PMID:10669625. |
fas and fasl have been detected in the vessel wall, and it has been proposed that fas-mediated apoptosis has a role in physiological and pathological cell turnover in the vasculature. |
2000-03-03 |
2023-08-12 |
human |
| M Sata, T Suhara, K Wals. Vascular endothelial cells and smooth muscle cells differ in expression of Fas and Fas ligand and in sensitivity to Fas ligand-induced cell death: implications for vascular disease and therapy. Arteriosclerosis, thrombosis, and vascular biology. vol 20. issue 2. 2000-03-03. PMID:10669625. |
we also examined the sensitivity of ecs and vsmcs to fas-mediated apoptosis induced by exposure to multiple fas agonists: soluble fasl, anti-fas antibody, and membrane-bound fasl resulting from transduction with a replication-defective adenovirus expressing fasl (adeno-fasl). |
2000-03-03 |
2023-08-12 |
human |
| Y Nomura, O Inanami, K Takahashi, A Matsuda, M Kuwabar. 2-Chloro-2'-deoxyadenosine induces apoptosis through the Fas/Fas ligand pathway in human leukemia cell line MOLT-4. Leukemia. vol 14. issue 2. 2000-03-02. PMID:10673748. |
these results indicated that 2cda-induced apoptosis was triggered by phosphorylation of 2cda followed by the protein synthesis-dependent expression of fas and fas-l and activation of caspases-8 and -3. |
2000-03-02 |
2023-08-12 |
human |
| J M Kim, J S Kim, H C Jung, I S Song, C Y Ki. Apoptosis of human gastric epithelial cells via caspase-3 activation in response to Helicobacter pylori infection: possible involvement of neutrophils through tumor necrosis factor alpha and soluble Fas ligands. Scandinavian journal of gastroenterology. vol 35. issue 1. 2000-03-01. PMID:10672833. |
apoptosis of human gastric epithelial cells via caspase-3 activation in response to helicobacter pylori infection: possible involvement of neutrophils through tumor necrosis factor alpha and soluble fas ligands. |
2000-03-01 |
2023-08-12 |
human |