| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| K Takeda, E Ohara, T Kaneda, K Hashimoto, M Sasak. [Increased serum soluble Fas ligand in hyperthyroid Graves' disease]. Rinsho byori. The Japanese journal of clinical pathology. vol 47. issue 10. 2000-02-11. PMID:10590671. |
the interaction of fas with its ligand (fasl) regulates a number of physiological and pathophysiological process of cell death or apoptosis. |
2000-02-11 |
2023-08-12 |
Not clear |
| J H Richburg, A Nañez, L R Williams, M E Embree, K Boekelheid. Sensitivity of testicular germ cells to toxicant-induced apoptosis in gld mice that express a nonfunctional form of Fas ligand. Endocrinology. vol 141. issue 2. 2000-02-10. PMID:10650961. |
sensitivity of testicular germ cells to toxicant-induced apoptosis in gld mice that express a nonfunctional form of fas ligand. |
2000-02-10 |
2023-08-12 |
mouse |
| J H Richburg, A Nañez, L R Williams, M E Embree, K Boekelheid. Sensitivity of testicular germ cells to toxicant-induced apoptosis in gld mice that express a nonfunctional form of Fas ligand. Endocrinology. vol 141. issue 2. 2000-02-10. PMID:10650961. |
recent evidence suggests that the fas signaling system is critical for the regulation of testicular germ cell apoptosis. |
2000-02-10 |
2023-08-12 |
mouse |
| J H Richburg, A Nañez, L R Williams, M E Embree, K Boekelheid. Sensitivity of testicular germ cells to toxicant-induced apoptosis in gld mice that express a nonfunctional form of Fas ligand. Endocrinology. vol 141. issue 2. 2000-02-10. PMID:10650961. |
to further evaluate the fas signaling system in testis, we examined the incidence of germ cell apoptosis in gld mice that lack a functional fas-signaling pathway. |
2000-02-10 |
2023-08-12 |
mouse |
| J H Richburg, A Nañez, L R Williams, M E Embree, K Boekelheid. Sensitivity of testicular germ cells to toxicant-induced apoptosis in gld mice that express a nonfunctional form of Fas ligand. Endocrinology. vol 141. issue 2. 2000-02-10. PMID:10650961. |
to test the role of the fas system in toxicant-induced germ cell apoptosis, mice were exposed to either a sertoli cell- or germ cell-specific toxicant [mono-(2-ethylhexyl)phthalate (mehp; 1 g/kg) or 5 gy radiation, respectively]. |
2000-02-10 |
2023-08-12 |
mouse |
| J H Richburg, A Nañez, L R Williams, M E Embree, K Boekelheid. Sensitivity of testicular germ cells to toxicant-induced apoptosis in gld mice that express a nonfunctional form of Fas ligand. Endocrinology. vol 141. issue 2. 2000-02-10. PMID:10650961. |
these data indicate that the fas signaling pathway is 1) involved in regulating the numbers of germ cells in the testis, 2) crucial for the initiation of germ cell apoptosis after mehp-induced sertoli cell injury, and 3) differentially active in the cell-specific regulation of germ cell apoptosis that occurs as a consequence of sertoli cell vs. germ cell injury. |
2000-02-10 |
2023-08-12 |
mouse |
| J H Kim, Y D Yoon, I Shin, J S Ha. Effects of ceramide, the Fas signal intermediate, on apoptosis and phospholipase D activity in mouse ovarian granulosa cells in vitro. IUBMB life. vol 48. issue 4. 2000-02-09. PMID:10632577. |
effects of ceramide, the fas signal intermediate, on apoptosis and phospholipase d activity in mouse ovarian granulosa cells in vitro. |
2000-02-09 |
2023-08-12 |
mouse |
| T Ogino, Y Ma, T A Than, M Omori, S Okad. Monochloramine enhances Fas (APO-1/CD95)-induced apoptosis in Jurkat T cells. Journal of leukocyte biology. vol 67. issue 1. 2000-02-09. PMID:10647997. |
monochloramine enhances fas (apo-1/cd95)-induced apoptosis in jurkat t cells. |
2000-02-09 |
2023-08-12 |
Not clear |
| T Ogino, Y Ma, T A Than, M Omori, S Okad. Monochloramine enhances Fas (APO-1/CD95)-induced apoptosis in Jurkat T cells. Journal of leukocyte biology. vol 67. issue 1. 2000-02-09. PMID:10647997. |
after 3 h of nh2cl treatment, when the apoptosis was beginning to increase, the cells showed cytochrome c release from mitochondria, proteolytic activation of caspase 9, and poly (adp-ribose) polymerase cleavage, regardless of fas stimulation. |
2000-02-09 |
2023-08-12 |
Not clear |
| T Ogino, Y Ma, T A Than, M Omori, S Okad. Monochloramine enhances Fas (APO-1/CD95)-induced apoptosis in Jurkat T cells. Journal of leukocyte biology. vol 67. issue 1. 2000-02-09. PMID:10647997. |
by contrast, fas stimulation alone resulted in neither cytochrome c release nor caspase 9 activation at 3 h, and the increase in the devd cleavage activity and apoptosis became evident at later time points. |
2000-02-09 |
2023-08-12 |
Not clear |
| M Yamaguchi, S Nadler, J W Lee, H J Dee. Induction of negative regulators of haematopoiesis in human bone marrow cells by HLA-DR cross-linking. Transplant immunology. vol 7. issue 3. 2000-02-07. PMID:10608299. |
furthermore, mab h81.9-induced apoptosis was prevented by anti-tnf alpha mab and by the soluble fas receptor, fas-ig, providing further evidence that the tnf effect was mediated via fas. |
2000-02-07 |
2023-08-12 |
human |
| K Newton, A Strasse. Ionizing radiation and chemotherapeutic drugs induce apoptosis in lymphocytes in the absence of Fas or FADD/MORT1 signaling. Implications for cancer therapy. The Journal of experimental medicine. vol 191. issue 1. 2000-02-07. PMID:10620618. |
ionizing radiation and chemotherapeutic drugs induce apoptosis in lymphocytes in the absence of fas or fadd/mort1 signaling. |
2000-02-07 |
2023-08-12 |
mouse |
| K Newton, A Strasse. Ionizing radiation and chemotherapeutic drugs induce apoptosis in lymphocytes in the absence of Fas or FADD/MORT1 signaling. Implications for cancer therapy. The Journal of experimental medicine. vol 191. issue 1. 2000-02-07. PMID:10620618. |
it has been reported that tumor cells treated with anticancer drugs increase surface expression of fas ligand (fasl) and are killed by autocrine or paracrine apoptosis signaling through fas (friesen, c., i. herr, p.h. |
2000-02-07 |
2023-08-12 |
mouse |
| K Newton, A Strasse. Ionizing radiation and chemotherapeutic drugs induce apoptosis in lymphocytes in the absence of Fas or FADD/MORT1 signaling. Implications for cancer therapy. The Journal of experimental medicine. vol 191. issue 1. 2000-02-07. PMID:10620618. |
these results demonstrate that apoptosis induced by ionizing radiation or anticancer drugs requires p53 and is regulated by the bcl-2 protein family but does not require signals transduced by fas and fadd/mort1. |
2000-02-07 |
2023-08-12 |
mouse |
| S Na, B Li, I S Grewal, H Enslen, R J Davis, J H Hanke, R A Flavel. Expression of activated CDC42 induces T cell apoptosis in thymus and peripheral lymph organs via different pathways. Oncogene. vol 18. issue 56. 2000-02-04. PMID:10637507. |
expression of fas and fas ligand on both thymocytes and peripheral t cells was upregulated in transgenic mice, but the increased apoptosis in the thymus was independent of fas (cd95), whereas peripheral spleen and lymph node t cell apoptosis was fas dependent. |
2000-02-04 |
2023-08-12 |
mouse |
| O Ebert, G Röpke, A Märten, P Lefterova, B Micka, P Buttgereit, S Niemitz, B Trojaneck, G Schmidt-Wolf, D Huhn, B Wittig, I G Schmidt-Wol. TNF-alpha secretion and apoptosis of lymphocytes mediated by gene transfer. Cytokines, cellular & molecular therapy. vol 5. issue 3. 2000-02-04. PMID:10641575. |
blockage of apoptosis and necrosis could be further increased by adding anti-fas-ligand (fasl) antibody, suggesting that induction of apoptosis via fasl and fas receptor (apo-1/cd95) may also play a role. |
2000-02-04 |
2023-08-12 |
Not clear |
| A Hara, N Yoshimi, Y Yamada, K Matsunaga, K Kawabata, S Sugie, H Mor. Effects of Fas-mediated liver cell apoptosis on diethylnitrosamine-induced hepatocarcinogenesis in mice. British journal of cancer. vol 82. issue 2. 2000-02-04. PMID:10646906. |
the present study was designed to investigate the effect of fas-mediated liver cell apoptosis, induced by a hamster monoclonal antibody against mouse fas antigen, on diethylnitrosamine (den)-induced hepatocarcinogenesis in mice. |
2000-02-04 |
2023-08-12 |
mouse |
| R Caricchio, P L Cohe. Spontaneous and induced apoptosis in systemic lupus erythematosus: multiple assays fail to reveal consistent abnormalities. Cellular immunology. vol 198. issue 1. 2000-02-01. PMID:10612651. |
in the present studies we examined the possibility that individual populations of t and b cells are abnormally resistant to apoptosis or that they stand out in over- or underexpressing fas. |
2000-02-01 |
2023-08-12 |
Not clear |
| R Caricchio, P L Cohe. Spontaneous and induced apoptosis in systemic lupus erythematosus: multiple assays fail to reveal consistent abnormalities. Cellular immunology. vol 198. issue 1. 2000-02-01. PMID:10612651. |
the results also raise questions concerning the dynamic expression of fas and the significance of ongoing apoptosis as a risk for autoimmune disease. |
2000-02-01 |
2023-08-12 |
Not clear |
| A Hammer, G Doh. Apoptotic nuclei within the uterine decidua of first trimester pregnancy arise from CD45 positive leukocytes. American journal of reproductive immunology (New York, N.Y. : 1989). vol 42. issue 2. 2000-01-31. PMID:10476690. |
as we were able to detect fasl on fetal trophoblast cells infiltrating the maternal uterine tissue and fas on decidual leukocytes (hammer et al., am j reprod immunol, 1999; 41: 41-51), we investigated whether apoptosis occurs in the maternal decidua during the first trimester of pregnancy. |
2000-01-31 |
2023-08-12 |
Not clear |