| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S Torii, D A Egan, R A Evans, J C Ree. Human Daxx regulates Fas-induced apoptosis from nuclear PML oncogenic domains (PODs). The EMBO journal. vol 18. issue 21. 2000-01-04. PMID:10545115. |
we show here that cells overexpressing the human homolog of daxx (hdaxx) display enhanced sensitivity to apoptosis induced by fas but not by several other cell death stimuli. |
2000-01-04 |
2023-08-12 |
human |
| S Torii, D A Egan, R A Evans, J C Ree. Human Daxx regulates Fas-induced apoptosis from nuclear PML oncogenic domains (PODs). The EMBO journal. vol 18. issue 21. 2000-01-04. PMID:10545115. |
taken together, these findings argue that hdaxx promotes sensitivity to fas from a nuclear location, probably by modulating the transcription of genes involved in fas-induced caspase activation and apoptosis. |
2000-01-04 |
2023-08-12 |
human |
| T Iwasaki, T Hamano, K Saheki, T Kuroiwa, Y Kataoka, Y Takemoto, A Ogata, A Sugihara, N Terada, J Fujimoto, E Kakishit. Effect of graft-versus-host disease (GVHD) on host hematopoietic progenitor cells is mediated by Fas-Fas ligand interactions but this does not explain the effect of GVHD on donor cells. Cellular immunology. vol 197. issue 1. 2000-01-04. PMID:10555993. |
although fas expression on repopulating donor cells also increased, fas-induced apoptosis by the repopulating donor cells was not remarkable until 12 weeks, when more than 90% of the cells were donor cells. |
2000-01-04 |
2023-08-12 |
mouse |
| J Hirota, T Furuichi, K Mikoshib. Inositol 1,4,5-trisphosphate receptor type 1 is a substrate for caspase-3 and is cleaved during apoptosis in a caspase-3-dependent manner. The Journal of biological chemistry. vol 274. issue 48. 1999-12-29. PMID:10567423. |
during apoptosis of the human t-cell line, jurkat cells, as induced by staurosporine or fas ligation, ip(3)r type 1 (ip(3)r1) was found to be cleaved. |
1999-12-29 |
2023-08-12 |
mouse |
| A I Aspinall, A Pinto, I A Auer, P Bridges, J Luider, L Dimnik, K D Patel, K Jorgenson, R C Woodma. Identification of new Fas mutations in a patient with autoimmune lymphoproliferative syndrome (ALPS) and eosinophilia. Blood cells, molecules & diseases. vol 25. issue 3-4. 1999-12-29. PMID:10575548. |
defective lymphocyte apoptosis caused by mutations of the fas (cd95) gene has been linked in the pathogenesis of alps, as binding of fas-ligand to fas can trigger apoptosis. |
1999-12-29 |
2023-08-12 |
Not clear |
| A I Aspinall, A Pinto, I A Auer, P Bridges, J Luider, L Dimnik, K D Patel, K Jorgenson, R C Woodma. Identification of new Fas mutations in a patient with autoimmune lymphoproliferative syndrome (ALPS) and eosinophilia. Blood cells, molecules & diseases. vol 25. issue 3-4. 1999-12-29. PMID:10575548. |
we speculate that the mutation in the death domain prevents the interaction of fas with intracellular mediators of apoptosis and is responsible for the autoimmune manifestations of alps and the abnormal lymphocytosis and eosinophilia in this patient. |
1999-12-29 |
2023-08-12 |
Not clear |
| M Blüher, K Krohn, H Wallaschofski, L E Braverman, R Paschk. Fas and Fas ligand gene expression in autoimmune thyroiditis in BB/W rats. European journal of endocrinology. vol 141. issue 5. 1999-12-28. PMID:10576768. |
apoptosis via the fas pathway is a potential mechanism for thyroid tissue destruction leading to clinical hypothyroidism in hashimoto's thyroiditis (ht). |
1999-12-28 |
2023-08-12 |
rat |
| S H Lee, M S Shin, W S Park, S Y Kim, S M Dong, H K Lee, J Y Park, R R Oh, J J Jang, J Y Lee, N J Yo. Immunohistochemical analysis of Fas ligand expression in normal human tissues. APMIS : acta pathologica, microbiologica, et immunologica Scandinavica. vol 107. issue 11. 1999-12-28. PMID:10598873. |
cross-linking of fas and fas ligand (fasl) induces apoptosis in fas-bearing cells and regulates apoptosis. |
1999-12-28 |
2023-08-12 |
human |
| T Hamada, S Komiya, H Yano, M Zenmyo, K Hiraoka, A Inoue, M Morimats. Modulation of fas-mediated apoptosis in osteosarcoma cell lines. International journal of oncology. vol 15. issue 6. 1999-12-27. PMID:10568818. |
fas/apo-1 (or cd95) is a 45-kda cell surface glycoprotein that transduces cellular death signals for apoptosis upon cross-linking with the fas ligand, which is experimentally replaced by anti-fas antibodies. |
1999-12-27 |
2023-08-12 |
Not clear |
| T Hamada, S Komiya, H Yano, M Zenmyo, K Hiraoka, A Inoue, M Morimats. Modulation of fas-mediated apoptosis in osteosarcoma cell lines. International journal of oncology. vol 15. issue 6. 1999-12-27. PMID:10568818. |
we examined the fas expression at the protein and mrna levels, and susceptibility to anti-fas-mediated apoptosis, in 14 osteosarcoma cell lines. |
1999-12-27 |
2023-08-12 |
Not clear |
| T Hamada, S Komiya, H Yano, M Zenmyo, K Hiraoka, A Inoue, M Morimats. Modulation of fas-mediated apoptosis in osteosarcoma cell lines. International journal of oncology. vol 15. issue 6. 1999-12-27. PMID:10568818. |
in the presence of the protein synthesis inhibitor cyclohexamide, antibody to fas led to an induction of apoptosis in ten of the osteosarcoma cell lines antibody-concentration dependently. |
1999-12-27 |
2023-08-12 |
Not clear |
| T Hamada, S Komiya, H Yano, M Zenmyo, K Hiraoka, A Inoue, M Morimats. Modulation of fas-mediated apoptosis in osteosarcoma cell lines. International journal of oncology. vol 15. issue 6. 1999-12-27. PMID:10568818. |
these data suggest that fas is a potential protein related to apoptosis in osteosarcomas when the sensitizing activity of cyclohexamide on anti-fas-mediated cytotoxicity was exerted. |
1999-12-27 |
2023-08-12 |
Not clear |
| A Villunger, N Ghaffari-Tabrizi, I Tinhofer, N Krumböck, B Bauer, T Schneider, S Kasibhatla, R Greil, G Baier-Bitterlich, F Uberall, D R Green, G Baie. Synergistic action of protein kinase C theta and calcineurin is sufficient for Fas ligand expression and induction of a crmA-sensitive apoptosis pathway in Jurkat T cells. European journal of immunology. vol 29. issue 11. 1999-12-23. PMID:10556809. |
synergistic action of protein kinase c theta and calcineurin is sufficient for fas ligand expression and induction of a crma-sensitive apoptosis pathway in jurkat t cells. |
1999-12-23 |
2023-08-12 |
Not clear |
| A Villunger, N Ghaffari-Tabrizi, I Tinhofer, N Krumböck, B Bauer, T Schneider, S Kasibhatla, R Greil, G Baier-Bitterlich, F Uberall, D R Green, G Baie. Synergistic action of protein kinase C theta and calcineurin is sufficient for Fas ligand expression and induction of a crmA-sensitive apoptosis pathway in Jurkat T cells. European journal of immunology. vol 29. issue 11. 1999-12-23. PMID:10556809. |
deletion of activated peripheral t cell clones by apoptosis requires the regulated expression of fas ligand (fasl) and sensitization of these cells to cd95-mediated signaling. |
1999-12-23 |
2023-08-12 |
Not clear |
| J Ouallet, N Baumann, Y Marie, H Villarroy. Fas system up-regulation in experimental autoimmune encephalomyelitis. Journal of the neurological sciences. vol 170. issue 2. 1999-12-23. PMID:10561524. |
fas and fas-ligand (fas-l) molecules are thought to play an important role in the deletion of autoimmune reactive t cells through apoptosis. |
1999-12-23 |
2023-08-12 |
mouse |
| X Zhao, D Yang, Z Pen. [Hepatocyte apoptosis in chronic viral hepatitis and its relationship with viral and Fas antigen expression]. Zhonghua nei ke za zhi. vol 36. issue 10. 1999-12-22. PMID:10436978. |
[hepatocyte apoptosis in chronic viral hepatitis and its relationship with viral and fas antigen expression]. |
1999-12-22 |
2023-08-12 |
Not clear |
| X Zhao, D Yang, Z Pen. [Hepatocyte apoptosis in chronic viral hepatitis and its relationship with viral and Fas antigen expression]. Zhonghua nei ke za zhi. vol 36. issue 10. 1999-12-22. PMID:10436978. |
to study the apoptosis of hepatocytes and its relationship with viral and fas antigen expression in viral hepatitis, we detected apoptosis of liver cell and the expression of viral and fas antigens in liver tissues of patients with chronic hepatitis b and/or c virus infection by using in situ end-labelling and immunohistochemical methods, respectively. |
1999-12-22 |
2023-08-12 |
Not clear |
| X Zhao, D Yang, Z Pen. [Hepatocyte apoptosis in chronic viral hepatitis and its relationship with viral and Fas antigen expression]. Zhonghua nei ke za zhi. vol 36. issue 10. 1999-12-22. PMID:10436978. |
there was no significant difference of apoptosis index between fas antigen positive and negative group. |
1999-12-22 |
2023-08-12 |
Not clear |
| C Naujokat, O Sezer, K Possinge. Tumor necrosis factor-alpha and interferon-gamma induce expression of functional Fas ligand on HT29 and MCF7 adenocarcinoma cells. Biochemical and biophysical research communications. vol 264. issue 3. 1999-12-22. PMID:10544014. |
tumor cells develop diverse mechanisms to escape from immune surveillance, including expression of fas ligand (fasl), a 40-kda type ii transmembrane protein that mediates apoptosis by binding to its cognate receptor fas (apo-1/cd95). |
1999-12-22 |
2023-08-12 |
human |
| C Naujokat, O Sezer, K Possinge. Tumor necrosis factor-alpha and interferon-gamma induce expression of functional Fas ligand on HT29 and MCF7 adenocarcinoma cells. Biochemical and biophysical research communications. vol 264. issue 3. 1999-12-22. PMID:10544014. |
upon activation, t lymphocytes and natural killer (nk) cells express fas and thus become sensitive to fasl-mediated apoptosis. |
1999-12-22 |
2023-08-12 |
human |