| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A Myc, P L Arscott, J D Bretz, N W Thompson, J R Bake. Characterization of FAP-1 expression and function in thyroid follicular cells. Endocrinology. vol 140. issue 11. 1999-11-22. PMID:10537175. |
fas-associated phosphatase-1 (fap-1) is a protein that has been shown to interact with the negative regulatory domain of fas and block fas-mediated apoptosis in fap-1 transfected jurkat cells. |
1999-11-22 |
2023-08-12 |
human |
| S Kitada, J M Zapata, M Andreeff, J C Ree. Bryostatin and CD40-ligand enhance apoptosis resistance and induce expression of cell survival genes in B-cell chronic lymphocytic leukaemia. British journal of haematology. vol 106. issue 4. 1999-11-19. PMID:10520003. |
b-cell chronic lymphocytic leukaemia (b-cll) cells were treated in vitro with cd40-ligand (cd40l) (cd154) or the protein kinase c modulator bryostatin-1, exploring the effects on: (a) sensitivity to apoptosis induction by chemotherapeutic drugs (fludarabine, dexamethasone) or anti-fas antibody; (b) expression of apoptosis-regulatory proteins (bcl-2, bcl-x, mcl-1, bax, bak, bag-1, flip, xiap); (c) expression of cell surface co-stimulatory antigens (cd80 [b7.1]; cd54 [icam-1]; cd70); and (d) expression of immune modulatory receptors (cd27, cd40, cd95 [fas]). |
1999-11-19 |
2023-08-12 |
Not clear |
| S Kitada, J M Zapata, M Andreeff, J C Ree. Bryostatin and CD40-ligand enhance apoptosis resistance and induce expression of cell survival genes in B-cell chronic lymphocytic leukaemia. British journal of haematology. vol 106. issue 4. 1999-11-19. PMID:10520003. |
despite elevations in the expression of cd95 (fas), anti-fas antibodies failed to induce apoptosis of cd40l- and bryostatin-treated b-cll cells. |
1999-11-19 |
2023-08-12 |
Not clear |
| J P Aubry, A Blaecke, S Lecoanet-Henchoz, P Jeannin, N Herbault, G Caron, V Moine, J Y Bonnefo. Annexin V used for measuring apoptosis in the early events of cellular cytotoxicity. Cytometry. vol 37. issue 3. 1999-11-19. PMID:10520200. |
the other effectors, fas l and tnf-alpha act by an apoptosis mechanism, leading to dna fragmentation. |
1999-11-19 |
2023-08-12 |
Not clear |
| S Hiroyasu, M Shiraishi, T Koji, T Mamadi, H Sugawa, H Tomori, Y Mut. Analysis of Fas system in pulmonary injury of graft-versus-host disease after rat intestinal transplantation. Transplantation. vol 68. issue 7. 1999-11-19. PMID:10532530. |
in conclusion, transcriptionally up-regulated fas ligand and increased number of apoptosis suggests that the fas system may play a role in the pathophysiology of gvhd-induced pulmonary injury. |
1999-11-19 |
2023-08-12 |
rat |
| M Fleck, J D Mountz, H C Hsu, J Wu, C K Edwards, E R Ker. Herpes simplex virus type 2 infection induced apoptosis in peritoneal macrophages independent of Fas and tumor necrosis factor-receptor signaling. Viral immunology. vol 12. issue 3. 1999-11-19. PMID:10532654. |
herpes simplex virus type 2 infection induced apoptosis in peritoneal macrophages independent of fas and tumor necrosis factor-receptor signaling. |
1999-11-19 |
2023-08-12 |
mouse |
| M Fleck, J D Mountz, H C Hsu, J Wu, C K Edwards, E R Ker. Herpes simplex virus type 2 infection induced apoptosis in peritoneal macrophages independent of Fas and tumor necrosis factor-receptor signaling. Viral immunology. vol 12. issue 3. 1999-11-19. PMID:10532654. |
though there was also an upregulation of fas (apo-1/cd95) and tumor necrosis factor (tnf)-receptor 1 (tnf-r1) pathways, inhibition of fas by soluble fas and blocking of tnf-alpha using a tnf-binding protein did not prevent hsv-induced apoptosis. |
1999-11-19 |
2023-08-12 |
mouse |
| M Fleck, J D Mountz, H C Hsu, J Wu, C K Edwards, E R Ker. Herpes simplex virus type 2 infection induced apoptosis in peritoneal macrophages independent of Fas and tumor necrosis factor-receptor signaling. Viral immunology. vol 12. issue 3. 1999-11-19. PMID:10532654. |
moreover, apoptosis was not impaired in hsv-2 infected macrophages from fas-deficient b6-lpr/lpr mice suggesting involvement of other apoptosis pathways, or activation of fas or tnf-r pathways downstream of the receptor level. |
1999-11-19 |
2023-08-12 |
mouse |
| M Fleck, J D Mountz, H C Hsu, J Wu, C K Edwards, E R Ker. Herpes simplex virus type 2 infection induced apoptosis in peritoneal macrophages independent of Fas and tumor necrosis factor-receptor signaling. Viral immunology. vol 12. issue 3. 1999-11-19. PMID:10532654. |
the present results demonstrate that hsv-2 infection leads to activation and subsequent apoptosis in peritoneal macrophages independent of fas or tnf-r1 signaling. |
1999-11-19 |
2023-08-12 |
mouse |
| J E Cardier, T Schulte, H Kammer, J Kwak, M Cardie. Fas (CD95, APO-1) antigen expression and function in murine liver endothelial cells: implications for the regulation of apoptosis in liver endothelial cells. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 13. issue 14. 1999-11-18. PMID:10544178. |
fas (cd95, apo-1) antigen expression and function in murine liver endothelial cells: implications for the regulation of apoptosis in liver endothelial cells. |
1999-11-18 |
2023-08-12 |
Not clear |
| J E Cardier, T Schulte, H Kammer, J Kwak, M Cardie. Fas (CD95, APO-1) antigen expression and function in murine liver endothelial cells: implications for the regulation of apoptosis in liver endothelial cells. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 13. issue 14. 1999-11-18. PMID:10544178. |
the fas (cd95, apo-1) receptor is a membrane-associated polypeptide that can mediate apoptosis in various cell types. |
1999-11-18 |
2023-08-12 |
Not clear |
| J E Cardier, T Schulte, H Kammer, J Kwak, M Cardie. Fas (CD95, APO-1) antigen expression and function in murine liver endothelial cells: implications for the regulation of apoptosis in liver endothelial cells. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 13. issue 14. 1999-11-18. PMID:10544178. |
the expression of fas by liver endothelial cells (lec) suggests that upon stimulation, apoptosis may occur in these cells. |
1999-11-18 |
2023-08-12 |
Not clear |
| J E Cardier, T Schulte, H Kammer, J Kwak, M Cardie. Fas (CD95, APO-1) antigen expression and function in murine liver endothelial cells: implications for the regulation of apoptosis in liver endothelial cells. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 13. issue 14. 1999-11-18. PMID:10544178. |
the doses of fas agonist required to induce lec-1 apoptosis were higher than those used previously in other cells, including hepatocytes, suggesting that lec-1 are highly resistant to the fas apoptotic pathway. |
1999-11-18 |
2023-08-12 |
Not clear |
| J E Cardier, T Schulte, H Kammer, J Kwak, M Cardie. Fas (CD95, APO-1) antigen expression and function in murine liver endothelial cells: implications for the regulation of apoptosis in liver endothelial cells. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 13. issue 14. 1999-11-18. PMID:10544178. |
up-regulation of vcam-1 and icam-1 was observed in lec-1 treated with a dose of fas agonist that does not induce apoptosis. |
1999-11-18 |
2023-08-12 |
Not clear |
| J E Cardier, T Schulte, H Kammer, J Kwak, M Cardie. Fas (CD95, APO-1) antigen expression and function in murine liver endothelial cells: implications for the regulation of apoptosis in liver endothelial cells. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 13. issue 14. 1999-11-18. PMID:10544178. |
to our knowledge, this is the first report that fas mediates apoptosis in lec, suggesting that apoptosis of these cells may participate in the liver damage observed in animals after receiving anti-fas mab or soluble fasl. |
1999-11-18 |
2023-08-12 |
Not clear |
| C T Smit Sibing. Immune effects of blood transfusion. Current opinion in hematology. vol 6. issue 6. 1999-11-16. PMID:10546801. |
the most interesting publication over the review period with regard to the core immune effects of blood transfusion relates to measured concentrations of active, soluble molecules like hla class i and ii and fas ligand molecules and to their in vitro immunomodulating effect as well as effects on induction of apoptosis. |
1999-11-16 |
2023-08-12 |
Not clear |
| M J Raftery, C K Behrens, A Müller, P H Krammer, H Walczak, G Schönric. Herpes simplex virus type 1 infection of activated cytotoxic T cells: Induction of fratricide as a mechanism of viral immune evasion. The Journal of experimental medicine. vol 190. issue 8. 1999-11-12. PMID:10523608. |
to dissect the underlying molecular events, we used a transgenic mouse model of hsv1 infection to demonstrate that cd95 (apo-1, fas)-triggered apoptosis is essential for hsv1-induced fratricide, whereas tumor necrosis factor (tnf) also contributes to this phenomenon but to a lesser extent. |
1999-11-12 |
2023-08-12 |
mouse |
| L Fan, K W Freeman, T Khan, E Pham, D M Spence. Improved artificial death switches based on caspases and FADD. Human gene therapy. vol 10. issue 14. 1999-11-10. PMID:10515447. |
we describe improved conditional fas and caspase 1, 3, 8, and 9 alleles that function at subnanomolar levels of the cid ap1903 to trigger apoptosis. |
1999-11-10 |
2023-08-12 |
Not clear |
| B R Gastman, Y Atarshi, T E Reichert, T Saito, L Balkir, H Rabinowich, T L Whitesid. Fas ligand is expressed on human squamous cell carcinomas of the head and neck, and it promotes apoptosis of T lymphocytes. Cancer research. vol 59. issue 20. 1999-11-10. PMID:10537320. |
fas ligand is expressed on human squamous cell carcinomas of the head and neck, and it promotes apoptosis of t lymphocytes. |
1999-11-10 |
2023-08-12 |
human |
| M Thangaraju, K Sharma, B Leber, D W Andrews, S H Shen, C B Srikan. Regulation of acidification and apoptosis by SHP-1 and Bcl-2. The Journal of biological chemistry. vol 274. issue 41. 1999-11-09. PMID:10506221. |
fas ligation also induces acidification-dependent apoptosis in a manner requiring the presence of shp-1 at the membrane. |
1999-11-09 |
2023-08-12 |
Not clear |