| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J R Schelling, R P Clevelan. Involvement of Fas-dependent apoptosis in renal tubular epithelial cell deletion in chronic renal failure. Kidney international. vol 56. issue 4. 1999-12-02. PMID:10504483. |
because the fas apoptosis pathway has been implicated in disease pathogenesis and fas is expressed in kidney, we hypothesized that fas-mediated renal tubule epithelial cell (rtc) apoptosis contributes to tubular atrophy in chronic renal failure. |
1999-12-02 |
2023-08-12 |
Not clear |
| J R Schelling, R P Clevelan. Involvement of Fas-dependent apoptosis in renal tubular epithelial cell deletion in chronic renal failure. Kidney international. vol 56. issue 4. 1999-12-02. PMID:10504483. |
immunohistochemical analyses of renal sections from two murine models of progressive renal disease revealed increases in rtc fas expression and apoptosis compared with tissue sections from age-matched control kidneys. |
1999-12-02 |
2023-08-12 |
Not clear |
| J R Schelling, R P Clevelan. Involvement of Fas-dependent apoptosis in renal tubular epithelial cell deletion in chronic renal failure. Kidney international. vol 56. issue 4. 1999-12-02. PMID:10504483. |
functional studies revealed that interleukin-1alpha-stimulated rtc fas expression was accompanied by increased apoptosis, which was inhibited by blocking anti-fas ligand antibodies. |
1999-12-02 |
2023-08-12 |
Not clear |
| Q L Deveraux, E Leo, H R Stennicke, K Welsh, G S Salvesen, J C Ree. Cleavage of human inhibitor of apoptosis protein XIAP results in fragments with distinct specificities for caspases. The EMBO journal. vol 18. issue 19. 1999-12-02. PMID:10508158. |
in this study, however, we demonstrate that endogenous xiap is cleaved into two fragments during apoptosis induced by the tumor necrosis factor family member fas (cd95). |
1999-12-02 |
2023-08-12 |
human |
| D Ashany, A Savir, N Bhardwaj, K B Elko. Dendritic cells are resistant to apoptosis through the Fas (CD95/APO-1) pathway. Journal of immunology (Baltimore, Md. : 1950). vol 163. issue 10. 1999-12-02. PMID:10553053. |
dendritic cells are resistant to apoptosis through the fas (cd95/apo-1) pathway. |
1999-12-02 |
2023-08-12 |
Not clear |
| D Ashany, A Savir, N Bhardwaj, K B Elko. Dendritic cells are resistant to apoptosis through the Fas (CD95/APO-1) pathway. Journal of immunology (Baltimore, Md. : 1950). vol 163. issue 10. 1999-12-02. PMID:10553053. |
however, apoptosis could be induced with c2-ceramide, suggesting that signals proximal to the generation of ceramide might mediate resistance to fas. |
1999-12-02 |
2023-08-12 |
Not clear |
| R K Lee, J P Cai, V Deyev, P S Gill, L Cabral, C Wood, R P Agarwal, W Xia, L H Boise, E Podack, W J Harringto. Azidothymidine and interferon-alpha induce apoptosis in herpesvirus-associated lymphomas. Cancer research. vol 59. issue 21. 1999-12-02. PMID:10554028. |
azt-mediated apoptosis was caspase dependent and occurred despite fas receptor blockade. |
1999-12-02 |
2023-08-12 |
human |
| T Sud. [Molecular mechanisms and biological roles of apoptosis and inflammation induced by Fas ligand]. Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme. vol 44. issue 10. 1999-11-30. PMID:10481604. |
[molecular mechanisms and biological roles of apoptosis and inflammation induced by fas ligand]. |
1999-11-30 |
2023-08-12 |
Not clear |
| I H Lee, W P Li, K B Hisert, L B Ivashki. Inhibition of interleukin 2 signaling and signal transducer and activator of transcription (STAT)5 activation during T cell receptor-mediated feedback inhibition of T cell expansion. The Journal of experimental medicine. vol 190. issue 9. 1999-11-30. PMID:10544198. |
tcr-induced apoptosis appears to require prior growth arrest, and is mediated by death receptors such as fas. |
1999-11-30 |
2023-08-12 |
human |
| S Srikanth, C C Franklin, R C Duke, R S Kraf. Human DU145 prostate cancer cells overexpressing mitogen-activated protein kinase phosphatase-1 are resistant to Fas ligand-induced mitochondrial perturbations and cellular apoptosis. Molecular and cellular biochemistry. vol 199. issue 1-2. 1999-11-30. PMID:10544965. |
human du145 prostate cancer cells overexpressing mitogen-activated protein kinase phosphatase-1 are resistant to fas ligand-induced mitochondrial perturbations and cellular apoptosis. |
1999-11-30 |
2023-08-12 |
human |
| S Srikanth, C C Franklin, R C Duke, R S Kraf. Human DU145 prostate cancer cells overexpressing mitogen-activated protein kinase phosphatase-1 are resistant to Fas ligand-induced mitochondrial perturbations and cellular apoptosis. Molecular and cellular biochemistry. vol 199. issue 1-2. 1999-11-30. PMID:10544965. |
mkp-1 overexpression in du-145 cells was also found to inhibit fas ligand (fasl)-induced apoptosis, as well as block the activation of caspases by fas engagement. |
1999-11-30 |
2023-08-12 |
human |
| J E Tanner, C Alfier. Epstein-Barr virus induces Fas (CD95) in T cells and Fas ligand in B cells leading to T-cell apoptosis. Blood. vol 94. issue 10. 1999-11-30. PMID:10552954. |
epstein-barr virus induces fas (cd95) in t cells and fas ligand in b cells leading to t-cell apoptosis. |
1999-11-30 |
2023-08-12 |
Not clear |
| O Cuvillier, E Mayhew, A S Janoff, S Spiege. Liposomal ET-18-OCH(3) induces cytochrome c-mediated apoptosis independently of CD95 (APO-1/Fas) signaling. Blood. vol 94. issue 10. 1999-11-30. PMID:10552970. |
furthermore, ell-12 had no effect on expression of cd95 ligand, and inhibition of the fas signaling pathway with antagonistic anti-cd95 antibody did not affect apoptosis induced by ell-12. |
1999-11-30 |
2023-08-12 |
Not clear |
| P L Arscott, T Stokes, A Myc, T J Giordano, N W Thompson, J R Bake. Fas (CD95) expression is up-regulated on papillary thyroid carcinoma. The Journal of clinical endocrinology and metabolism. vol 84. issue 11. 1999-11-26. PMID:10566680. |
thyrocyte apoptosis signaled through the fas receptor has been proposed as a mechanism for the cytotoxicity observed in thyroiditis, but the role the fas pathway plays in thyroid cancer is not known. |
1999-11-26 |
2023-08-12 |
Not clear |
| M Hornig, H Weissenböck, N Horscroft, W I Lipki. An infection-based model of neurodevelopmental damage. Proceedings of the National Academy of Sciences of the United States of America. vol 96. issue 21. 1999-11-24. PMID:10518583. |
neurons are lost predominantly by apoptosis, as supported by increased mrna levels for pro-apoptotic products (fas, caspase-1), decreased mrna levels for the anti-apoptotic bcl-x, and in situ labeling of fragmented dna. |
1999-11-24 |
2023-08-12 |
human |
| D J Askew, U Kuscuoglu, T Brunner, D R Green, R L Miesfel. Characterization of Apt- cell lines exhibiting cross-resistance to glucocorticoid- and Fas-mediated apoptosis. Cell death and differentiation. vol 6. issue 8. 1999-11-23. PMID:10467354. |
apoptosis induction by staurosporine, ceramide, and fas stimulation was investigated in the mouse thymoma cell line w7.2 and a panel of dexamethasone (dex)-resistant w7.2 mutant cell lines, apt3.8, apt4.8 and apt5.8, and a bcl-2 transfected w7.2 cell line (wbcl2). |
1999-11-23 |
2023-08-12 |
mouse |
| D J Askew, U Kuscuoglu, T Brunner, D R Green, R L Miesfel. Characterization of Apt- cell lines exhibiting cross-resistance to glucocorticoid- and Fas-mediated apoptosis. Cell death and differentiation. vol 6. issue 8. 1999-11-23. PMID:10467354. |
transient transfection of human fas gene coding sequences into the apt- mutants and wbcl2 cells did not induce apoptosis, even though these same cell lines were sensitive to ectopic expression of the fadd and caspase 8 genes. |
1999-11-23 |
2023-08-12 |
mouse |
| R L Thomas, C M Matsko, M T Lotze, A A Amoscat. Mass spectrometric identification of increased C16 ceramide levels during apoptosis. The Journal of biological chemistry. vol 274. issue 43. 1999-11-23. PMID:10521441. |
increases in long term c16 ceramide accumulation were also seen in fas-induced apoptosis, which occurred at time points greater than 2 h. analysis of mitochondrial modifications using the mitochondrial probe nonyl acridine orange (nao) indicated that initial increases in c16 ceramide levels closely paralleled the decrease in mitochondrial mass during fas or radiation-induced apoptosis. |
1999-11-23 |
2023-08-12 |
Not clear |
| F Rieux-Laucat, S Blachère, S Danielan, J P De Villartay, M Oleastro, E Solary, B Bader-Meunier, P Arkwright, C Pondaré, F Bernaudin, H Chapel, S Nielsen, M Berrah, A Fischer, F Le Deis. Lymphoproliferative syndrome with autoimmunity: A possible genetic basis for dominant expression of the clinical manifestations. Blood. vol 94. issue 8. 1999-11-22. PMID:10515860. |
in vitro studies show that lymphocytes from all fas mutant carriers exhibit a fas-antibody-induced apoptosis defect. |
1999-11-22 |
2023-08-12 |
human |
| F Rieux-Laucat, S Blachère, S Danielan, J P De Villartay, M Oleastro, E Solary, B Bader-Meunier, P Arkwright, C Pondaré, F Bernaudin, H Chapel, S Nielsen, M Berrah, A Fischer, F Le Deis. Lymphoproliferative syndrome with autoimmunity: A possible genetic basis for dominant expression of the clinical manifestations. Blood. vol 94. issue 8. 1999-11-22. PMID:10515860. |
these results also indicate that the currently available antibody-mediated in vitro apoptosis assay does not necessarily reflect the in vivo ability of abnormal fas molecules to trigger lymphocyte death. |
1999-11-22 |
2023-08-12 |
human |