| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Y Choi, V R Ramnath, A S Eaton, A Chen, K L Simon-Stoos, D E Kleiner, J Erikson, J M Puc. Expression in transgenic mice of dominant interfering Fas mutations: a model for human autoimmune lymphoproliferative syndrome. Clinical immunology (Orlando, Fla.). vol 93. issue 1. 1999-11-05. PMID:10497009. |
therefore defective murine fas proteins act in a dominant manner to impair apoptosis of activated lymphocytes and disrupt lymphocyte homeostasis. |
1999-11-05 |
2023-08-12 |
mouse |
| R Caricchio, D Kovalenko, W K Kaufmann, P L Cohe. Apoptosis provoked by the oxidative stress inducer menadione (Vitamin K(3)) is mediated by the Fas/Fas ligand system. Clinical immunology (Orlando, Fla.). vol 93. issue 1. 1999-11-05. PMID:10497012. |
vk(3) induced apoptosis in jurkat cells, coincident with an increase in both fas and fasl expression. |
1999-11-05 |
2023-08-12 |
mouse |
| I Elovaara, F Sabri, F Gray, I Alafuzoff, F Chiod. Upregulated expression of Fas and Fas ligand in brain through the spectrum of HIV-1 infection. Acta neuropathologica. vol 98. issue 4. 1999-11-05. PMID:10502040. |
the fas expression on glial cells in asymptomatic hiv-1 infection may indicate apoptosis already in the asymptomatic stage of hiv-1 disease. |
1999-11-05 |
2023-08-12 |
Not clear |
| L Qiao, G C Farrel. The effects of cell density, attachment substratum and dexamethasone on spontaneous apoptosis of rat hepatocytes in primary culture. In vitro cellular & developmental biology. Animal. vol 35. issue 7. 1999-11-04. PMID:10462206. |
bax was more highly expressed in cells cultured at high density, and on collagen vs. matrigel, whereas changes of bcl-2 and fas expression observed in culture appeared unrelated to the rate of apoptosis. |
1999-11-04 |
2023-08-12 |
rat |
| T Otsuki, K Ichihara, A Tomokuni, H Sakaguchi, T Aikoh, T Matsuki, Y Isozaki, F Hyodoh, M Kusaka, S Kita, A Uek. Evaluation of cases with silicosis using the parameters related to Fas-mediated apoptosis. International journal of molecular medicine. vol 4. issue 4. 1999-11-04. PMID:10493983. |
to establish a new clinical index for immunological abnormalities occurring in silicosis, several clinical parameters related to fas-mediated apoptosis; i.e., membrane fas expression on peripheral blood lymphocytes (mfas), serum soluble fas levels (sfas), serum soluble fas ligand levels (sfasl), and soluble/membrane fas mrna expression ratios (s/mfas exr) in peripheral blood mononuclear cells (pbmc) were investigated. |
1999-11-04 |
2023-08-12 |
human |
| B Wedi, J Straede, B Wieland, A Kap. Eosinophil apoptosis is mediated by stimulators of cellular oxidative metabolisms and inhibited by antioxidants: involvement of a thiol-sensitive redox regulation in eosinophil cell death. Blood. vol 94. issue 7. 1999-11-04. PMID:10498608. |
moreover, gsh and nac significantly reduced eosinophil apoptosis mediated by a monoclonal antibody directed to fas antigen. |
1999-11-04 |
2023-08-12 |
Not clear |
| M Konopleva, S Zhao, Z Xie, H Segall, A Younes, D F Claxton, Z Estrov, S M Kornblau, M Andreef. Apoptosis. Molecules and mechanisms. Advances in experimental medicine and biology. vol 457. 1999-11-04. PMID:10500797. |
chemotherapy, radiation, fas ligation), modulators of apoptosis (e.g. |
1999-11-04 |
2023-08-12 |
Not clear |
| B Drénou, V Blancheteau, D H Burgess, R Fauchet, D J Charron, N A Moone. A caspase-independent pathway of MHC class II antigen-mediated apoptosis of human B lymphocytes. Journal of immunology (Baltimore, Md. : 1950). vol 163. issue 8. 1999-11-04. PMID:10510346. |
in marked comparison with fas, the cell-permeable and irreversible caspase inhibitors zvad-fmk and devd-fmk failed to inhibit hla-dr-mediated apoptosis. |
1999-11-04 |
2023-08-12 |
human |
| A B Kamath, I Camacho, P S Nagarkatti, M Nagarkatt. Role of Fas-Fas ligand interactions in 2,3,7,8-tetrachlorodibenzo- p-dioxin (TCDD)-induced immunotoxicity: increased resistance of thymocytes from Fas-deficient (lpr) and Fas ligand-defective (gld) mice to TCDD-induced toxicity. Toxicology and applied pharmacology. vol 160. issue 2. 1999-11-04. PMID:10527913. |
the sera from tcdd-treated wild-type mice exhibited increased levels of soluble fas ligand, inasmuch as incubation of fas(+), but not fas(-) cells with the sera, triggered apoptosis. |
1999-11-04 |
2023-08-12 |
mouse |
| S Ekmekcioglu, M F Okcu, M I Colome-Grimmer, L Owen-Schaub, A C Buzaid, E A Grim. Differential increase of Fas ligand expression on metastatic and thin or thick primary melanoma cells compared with interleukin-10. Melanoma research. vol 9. issue 3. 1999-11-03. PMID:10465582. |
fas ligand (fasl), a cell surface molecule belonging to the tumour necrosis factor family, binds to its receptor fas and thus induces apoptosis of fas-bearing cells such as activated lymphocytes. |
1999-11-03 |
2023-08-12 |
Not clear |
| M Higuchi, T Horiuchi, T Sawabe, S Yoshizawa, K Nagasawa, Y Nih. Establishment and characterization of a Fas-resistant T cell line. Acta haematologica. vol 102. issue 1. 1999-11-03. PMID:10473884. |
fas is a cell surface receptor that controls a signal transduction pathway leading to apoptosis. |
1999-11-03 |
2023-08-12 |
human |
| T L Whitesid. Signaling defects in T lymphocytes of patients with malignancy. Cancer immunology, immunotherapy : CII. vol 48. issue 7. 1999-11-02. PMID:10501846. |
while no correlation could be established between the proportions of cells with low zeta chain expression and those that spontaneously apoptose ex vivo, the zeta chain has been shown to be cleaved by caspases in t cells coincubated with tumor cells or with t cells exposed to ch-11 antibody, which induces apoptosis upon crosslinking fas on the cell surface. |
1999-11-02 |
2023-08-12 |
Not clear |
| H Ben-Hur, E Plonsky, V Berman, Y Tendler, P Gurevich, E Moriel, M Guy, B Sandler, I Zusma. Transplacental effects of IgG generated against soluble 53 kDa protein on the splenic lymph system of rat progeny exposed to carcinogen: rate of apoptosis, proliferation of lymphocytes and expression of Fas and Fas ligand proteins. European journal of gynaecological oncology. vol 20. issue 4. 1999-11-01. PMID:10475129. |
transplacental effects of igg generated against soluble 53 kda protein on the splenic lymph system of rat progeny exposed to carcinogen: rate of apoptosis, proliferation of lymphocytes and expression of fas and fas ligand proteins. |
1999-11-01 |
2023-08-12 |
rat |
| A de la Coste, M Fabre, N McDonell, A Porteu, H Gilgenkrantz, C Perret, A Kahn, A Migno. Differential protective effects of Bcl-xL and Bcl-2 on apoptotic liver injury in transgenic mice. The American journal of physiology. vol 277. issue 3. 1999-10-28. PMID:10484397. |
fas ligand (cd95l) and tumor necrosis factor-alpha (tnf-alpha) are pivotal inducers of hepatocyte apoptosis. |
1999-10-28 |
2023-08-12 |
mouse |
| N Mitsiades, V Poulaki, A Leone, M Tsoko. Fas-mediated apoptosis in Ewing's sarcoma cell lines by metalloproteinase inhibitors. Journal of the National Cancer Institute. vol 91. issue 19. 1999-10-28. PMID:10511596. |
fas ligand (fasl) is a transmembrane protein that induces apoptosis (programmed cell death) in susceptible cells by interacting with its receptor, fas. |
1999-10-28 |
2023-08-12 |
Not clear |
| L Xerri, E Devilard, R Bouabdallah, A M Stoppa, J Hassoun, F Bir. FADD expression and caspase activation in B-cell lymphomas resistant to Fas-mediated apoptosis. British journal of haematology. vol 106. issue 3. 1999-10-26. PMID:10468853. |
fas stimulation alone induced neither significant apoptosis nor significant changes in the expression profiles of fadd, caspases 3 and 8 and parp in the 16 samples, except for variations in fadd and caspase 8 expression levels in a minority of samples. |
1999-10-26 |
2023-08-12 |
Not clear |
| L Xerri, E Devilard, R Bouabdallah, A M Stoppa, J Hassoun, F Bir. FADD expression and caspase activation in B-cell lymphomas resistant to Fas-mediated apoptosis. British journal of haematology. vol 106. issue 3. 1999-10-26. PMID:10468853. |
our results showed (1) that induction of apoptosis in b-nhls by fas/cd40 co-stimulation used the same caspase executioner machinery as the normal fas pathway, and (2) that nhl cells which resisted fas-mediated apoptosis displayed no defect in either expression or functionality of caspases 3 and 8, nor in fadd expression. |
1999-10-26 |
2023-08-12 |
Not clear |
| R Tani, S Ozaki, M Kosaka, S Fujiwara, H Shibata, S Wakatsuki, T Matsumot. Fas ligand-induced apoptosis of hepatocytes in natural killer cell leukaemia. British journal of haematology. vol 106. issue 3. 1999-10-26. PMID:10468861. |
fas ligand-induced apoptosis of hepatocytes in natural killer cell leukaemia. |
1999-10-26 |
2023-08-12 |
Not clear |
| S C Hsu, M A Gavrilin, H H Lee, C C Wu, S H Han, M Z La. NF-kappa B-dependent Fas ligand expression. European journal of immunology. vol 29. issue 9. 1999-10-26. PMID:10508269. |
apoptosis of lymphocytes is triggered by different stimuli through the induced expression of fas and fas ligand (fasl). |
1999-10-26 |
2023-08-12 |
Not clear |
| S C Hsu, M A Gavrilin, H H Lee, C C Wu, S H Han, M Z La. NF-kappa B-dependent Fas ligand expression. European journal of immunology. vol 29. issue 9. 1999-10-26. PMID:10508269. |
in contrast, camp weakly interfered with activation-induced fas expression, and the remaining fas molecules on camp-treated t cells still mediated apoptosis. |
1999-10-26 |
2023-08-12 |
Not clear |