| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M S Razzaque, T Koji, A Kumatori, T Taguch. Cisplatin-induced apoptosis in human proximal tubular epithelial cells is associated with the activation of the Fas/Fas ligand system. Histochemistry and cell biology. vol 111. issue 5. 1999-09-24. PMID:10403114. |
the results showed that: (1) cp-treatment resulted in a decreased number of live human ptecs and an increased number of dead cells, (2) cp-treated human ptecs showed an increased rate of apoptosis with its typical morphological features, and (3) expression of both fas and fas-l was upregulated in cp-treated human ptecs. |
1999-09-24 |
2023-08-12 |
human |
| Y Y Fan, J Zhang, R Barhoumi, R C Burghardt, N D Turner, J R Lupton, R S Chapki. Antagonism of CD95 signaling blocks butyrate induction of apoptosis in young adult mouse colonic cells. The American journal of physiology. vol 277. issue 2. 1999-09-23. PMID:10444408. |
soluble fas receptor protein (fas:fc chimera) and caspase inhibitors (z-vad-fmk and z-ietd-fmk) blocked butyrate induction of apoptosis. |
1999-09-23 |
2023-08-12 |
mouse |
| Y Y Fan, J Zhang, R Barhoumi, R C Burghardt, N D Turner, J R Lupton, R S Chapki. Antagonism of CD95 signaling blocks butyrate induction of apoptosis in young adult mouse colonic cells. The American journal of physiology. vol 277. issue 2. 1999-09-23. PMID:10444408. |
therefore, fas receptor-dependent signal transduction is involved in butyrate induction of apoptosis in colonocytes. |
1999-09-23 |
2023-08-12 |
mouse |
| G Filippatos, C Leche, R Sunga, A Tsoukas, P Anthopoulos, I Joshi, A Bifero, R Pick, B D Uha. Expression of FAS adjacent to fibrotic foci in the failing human heart is not associated with increased apoptosis. The American journal of physiology. vol 277. issue 2. 1999-09-23. PMID:10444467. |
expression of fas adjacent to fibrotic foci in the failing human heart is not associated with increased apoptosis. |
1999-09-23 |
2023-08-12 |
human |
| G Filippatos, C Leche, R Sunga, A Tsoukas, P Anthopoulos, I Joshi, A Bifero, R Pick, B D Uha. Expression of FAS adjacent to fibrotic foci in the failing human heart is not associated with increased apoptosis. The American journal of physiology. vol 277. issue 2. 1999-09-23. PMID:10444467. |
we hypothesized that viable heart cells adjacent to fibrotic foci might become "predisposed" to apoptosis by expression of the receptor fas (apo1, cd95). |
1999-09-23 |
2023-08-12 |
human |
| G Filippatos, C Leche, R Sunga, A Tsoukas, P Anthopoulos, I Joshi, A Bifero, R Pick, B D Uha. Expression of FAS adjacent to fibrotic foci in the failing human heart is not associated with increased apoptosis. The American journal of physiology. vol 277. issue 2. 1999-09-23. PMID:10444467. |
heart cell apoptosis, fibrosis, and fas expression were studied by propidium iodide and in situ end labeling (isel) of dna, picrosirius red staining, and immunohistochemistry. |
1999-09-23 |
2023-08-12 |
human |
| G Filippatos, C Leche, R Sunga, A Tsoukas, P Anthopoulos, I Joshi, A Bifero, R Pick, B D Uha. Expression of FAS adjacent to fibrotic foci in the failing human heart is not associated with increased apoptosis. The American journal of physiology. vol 277. issue 2. 1999-09-23. PMID:10444467. |
regardless of the extent of fibrosis or detectable apoptosis, fas expression was observed in regions immediately adjacent to the fibrosis, but not in regions distal to fibrosis, nor in fibrotic areas devoid of nuclei. |
1999-09-23 |
2023-08-12 |
human |
| L S Gutierrez, M Eliza, T Niven-Fairchild, F Naftolin, G Mo. The Fas/Fas-ligand system: a mechanism for immune evasion in human breast carcinomas. Breast cancer research and treatment. vol 54. issue 3. 1999-09-23. PMID:10445423. |
moreover, we describe the presence of apoptosis and fas expression in the lymphocytic population surrounding the tumor. |
1999-09-23 |
2023-08-12 |
human |
| M Shiraishi, S Hiroyasu, T Oshiro, M Nagahama, H Tomori, T Mamadi, Y Mut. Early detection of apoptosis and fas ligand expression in hepatic graft-versus-host disease after rat small bowel transplantation. The Journal of surgical research. vol 86. issue 1. 1999-09-23. PMID:10452880. |
early detection of apoptosis and fas ligand expression in hepatic graft-versus-host disease after rat small bowel transplantation. |
1999-09-23 |
2023-08-12 |
rat |
| F M Ruemmele, P Russo, J Beaulieu, S Dionne, E Levy, M J Lentze, E G Seidma. Susceptibility to FAS-induced apoptosis in human nontumoral enterocytes: role of costimulatory factors. Journal of cellular physiology. vol 181. issue 1. 1999-09-23. PMID:10457352. |
in the present study, the regulation of enterocyte fas and fas ligand expression by cytokines and its functional role in human intestinal epithelial cell apoptosis and proliferation were analyzed with two different models: a nontransformed human intestinal epithelial cell line (hiec) and normal colonic explant cultures. |
1999-09-23 |
2023-08-12 |
human |
| F M Ruemmele, P Russo, J Beaulieu, S Dionne, E Levy, M J Lentze, E G Seidma. Susceptibility to FAS-induced apoptosis in human nontumoral enterocytes: role of costimulatory factors. Journal of cellular physiology. vol 181. issue 1. 1999-09-23. PMID:10457352. |
the sensitizing effect to fas-induced apoptosis was mediated via tnfalpha- and ifngamma-induced upregulation of fas expression (maximally 348%). |
1999-09-23 |
2023-08-12 |
human |
| F M Ruemmele, P Russo, J Beaulieu, S Dionne, E Levy, M J Lentze, E G Seidma. Susceptibility to FAS-induced apoptosis in human nontumoral enterocytes: role of costimulatory factors. Journal of cellular physiology. vol 181. issue 1. 1999-09-23. PMID:10457352. |
these findings suggest that, despite the fact that normal human enterocytes express fas, costimulatory factors, such as tnfalpha or ifngamma, abundantly secreted under inflammatory conditions, are necessary to sensitize intestinal epithelial cells to fas-induced apoptosis by upregulating this receptor. |
1999-09-23 |
2023-08-12 |
human |
| Y Inazawa, S Yonehar. Fas-induced in vivo apoptosis in bone marrow: anti-Fas mAb-induced elimination and successive proliferation of Fas-expressing cells especially those of myeloid lineage. Cell structure and function. vol 24. issue 3. 1999-09-23. PMID:10462177. |
thus, fas is functional in normal bone marrow and fas-induced apoptosis in bone marrow enhances marked proliferation of fas-expressing myeloid precursor cells in vivo. |
1999-09-23 |
2023-08-12 |
mouse |
| X M Yin, K Wang, A Gross, Y Zhao, S Zinkel, B Klocke, K A Roth, S J Korsmeye. Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis. Nature. vol 400. issue 6747. 1999-09-23. PMID:10476969. |
we find that when these mice are injected with an antibody directed against fas, they nearly all survive, whereas wild-type mice die from hepatocellular apoptosis and haemorrhagic necrosis. |
1999-09-23 |
2023-08-12 |
mouse |
| B B Ambar, K Frei, U Malipiero, A E Morelli, M G Castro, P R Lowenstein, A Fontan. Treatment of experimental glioma by administration of adenoviral vectors expressing Fas ligand. Human gene therapy. vol 10. issue 10. 1999-09-22. PMID:10428209. |
fas ligand (fasl) is a cytokine, produced by activated t cells and nk cells, that triggers apoptosis of fas-positive target cells including human glioma cells. |
1999-09-22 |
2023-08-12 |
human |
| D Josefsen, J H Myklebust, D H Lynch, T Stokke, H K Blomhoff, E B Smelan. Fas ligand promotes cell survival of immature human bone marrow CD34+CD38- hematopoietic progenitor cells by suppressing apoptosis. Experimental hematology. vol 27. issue 9. 1999-09-22. PMID:10480436. |
fas ligand promotes cell survival of immature human bone marrow cd34+cd38- hematopoietic progenitor cells by suppressing apoptosis. |
1999-09-22 |
2023-08-12 |
human |
| D Josefsen, J H Myklebust, D H Lynch, T Stokke, H K Blomhoff, E B Smelan. Fas ligand promotes cell survival of immature human bone marrow CD34+CD38- hematopoietic progenitor cells by suppressing apoptosis. Experimental hematology. vol 27. issue 9. 1999-09-22. PMID:10480436. |
signaling through fas has previously been shown to induce apoptosis of cd34+ human hematopoietic progenitor cells after exposure to ifn-gamma or tfn-alpha. |
1999-09-22 |
2023-08-12 |
human |
| M Tsuboi, A Kawakami, T Nakashima, N Matsuoka, S Urayama, Y Kawabe, K Fujiyama, T Kiriyama, T Aoyagi, K Maeda, K Eguch. Tumor necrosis factor-alpha and interleukin-1beta increase the Fas-mediated apoptosis of human osteoblasts. The Journal of laboratory and clinical medicine. vol 134. issue 3. 1999-09-22. PMID:10482306. |
our recent work demonstrated functional fas expression on human osteoblasts, and the histologic examination of the periarticular osteoporosis region in patients with rheumatoid arthritis (ra) showed apoptosis in osteoblasts. |
1999-09-22 |
2023-08-12 |
human |
| M Tsuboi, A Kawakami, T Nakashima, N Matsuoka, S Urayama, Y Kawabe, K Fujiyama, T Kiriyama, T Aoyagi, K Maeda, K Eguch. Tumor necrosis factor-alpha and interleukin-1beta increase the Fas-mediated apoptosis of human osteoblasts. The Journal of laboratory and clinical medicine. vol 134. issue 3. 1999-09-22. PMID:10482306. |
fas expression on these cells was examined by flow cytometry, and fas-mediated apoptosis induced by anti-fas immunoglobulin m (igm) was determined by a chromium 51 release assay, the presence of cells with hypodiploid dna, staining with hoechst 33258 dye, and the detection of dna fragmentation on agarose gel electrophoresis. |
1999-09-22 |
2023-08-12 |
human |
| M Tsuboi, A Kawakami, T Nakashima, N Matsuoka, S Urayama, Y Kawabe, K Fujiyama, T Kiriyama, T Aoyagi, K Maeda, K Eguch. Tumor necrosis factor-alpha and interleukin-1beta increase the Fas-mediated apoptosis of human osteoblasts. The Journal of laboratory and clinical medicine. vol 134. issue 3. 1999-09-22. PMID:10482306. |
tnf-alpha augmented both fas expression and fas-mediated apoptosis more efficiently than did il-1beta. |
1999-09-22 |
2023-08-12 |
human |