Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
K Kimura, E P Gelman. Tumor necrosis factor-alpha and Fas activate complementary Fas-associated death domain-dependent pathways that enhance apoptosis induced by gamma-irradiation. The Journal of biological chemistry. vol 275. issue 12. 2000-04-27. PMID:10722700. |
tumor necrosis factor-alpha and fas activate complementary fas-associated death domain-dependent pathways that enhance apoptosis induced by gamma-irradiation. |
2000-04-27 |
2023-08-12 |
human |
T Lin, L Genestier, M J Pinkoski, A Castro, S Nicholas, R Mogil, F Paris, Z Fuks, E H Schuchman, R N Kolesnick, D R Gree. Role of acidic sphingomyelinase in Fas/CD95-mediated cell death. The Journal of biological chemistry. vol 275. issue 12. 2000-04-27. PMID:10722706. |
similarly, activation-induced apoptosis of t lymphocytes was unaffected by the status of asmase, and asmase(-/-) mice failed to show immunological symptoms seen in animals with defects in fas function. |
2000-04-27 |
2023-08-12 |
mouse |
A A Ruefli, M J Smyth, R W Johnston. HMBA induces activation of a caspase-independent cell death pathway to overcome P-glycoprotein-mediated multidrug resistance. Blood. vol 95. issue 7. 2000-04-27. PMID:10733510. |
as well as effluxing xenotoxins, functional p-gp can confer resistance to caspase-dependent apoptosis induced by a range of different stimuli, including fas ligand, tumor necrosis factor, uv irradiation, and serum starvation. |
2000-04-27 |
2023-08-12 |
Not clear |
T Kobayashi, K Okamoto, T Kobata, T Hasunuma, T Kato, H Hamada, K Nishiok. Novel gene therapy for rheumatoid arthritis by FADD gene transfer: induction of apoptosis of rheumatoid synoviocytes but not chondrocytes. Gene therapy. vol 7. issue 6. 2000-04-26. PMID:10757027. |
rheumatoid synovial cells express functional fas antigen and are susceptible to fas-mediated apoptosis. |
2000-04-26 |
2023-08-12 |
mouse |
F Puppo, P Contini, M Ghio, S Brenci, M Scudeletti, G Filaci, S Ferrone, F Indiver. Soluble human MHC class I molecules induce soluble Fas ligand secretion and trigger apoptosis in activated CD8(+) Fas (CD95)(+) T lymphocytes. International immunology. vol 12. issue 2. 2000-04-24. PMID:10653855. |
soluble human mhc class i molecules induce soluble fas ligand secretion and trigger apoptosis in activated cd8(+) fas (cd95)(+) t lymphocytes. |
2000-04-24 |
2023-08-12 |
human |
F Puppo, P Contini, M Ghio, S Brenci, M Scudeletti, G Filaci, S Ferrone, F Indiver. Soluble human MHC class I molecules induce soluble Fas ligand secretion and trigger apoptosis in activated CD8(+) Fas (CD95)(+) T lymphocytes. International immunology. vol 12. issue 2. 2000-04-24. PMID:10653855. |
apoptosis is induced by the interaction of fas (cd95)(+) cells with soluble fas ligand which is released following binding of shla-i antigens to cd8 molecules. |
2000-04-24 |
2023-08-12 |
human |
E Zuñiga, C Motran, C L Montes, F L Diaz, J L Bocco, A Grupp. Trypanosoma cruzi-induced immunosuppression: B cells undergo spontaneous apoptosis and lipopolysaccharide (LPS) arrests their proliferation during acute infection. Clinical and experimental immunology. vol 119. issue 3. 2000-04-24. PMID:10691924. |
furthermore, these activated b cells also exhibited an increase in fas expression and apoptosis in cultures without an exogenous stimulus. |
2000-04-24 |
2023-08-12 |
mouse |
A Nakajima, H Hirai, N Kayagaki, S Yoshino, S Hirose, H Yagita, K Okumur. Treatment of lupus in NZB/W F1 mice with monoclonal antibody against Fas ligand. Journal of autoimmunity. vol 14. issue 2. 2000-04-21. PMID:10677246. |
since fas ligand (fasl) can induce apoptosis of fas-bearing cells, fas/fasl interactions can play a critical role in maintaining self-tolerance. |
2000-04-21 |
2023-08-12 |
mouse |
H Ben-Hur, P Gurevich, M Huszar, A Ben-Arie, V Berman, Y Tendler, O Zinder, R Tchanishev, S Gershon, G Mor, Y Zaltsman, F Kohen, I Zusma. Apoptosis and apoptosis-related proteins (Fas, Fas ligand, Blc-2, p53) in lymphoid elements of human ovarian tumors. European journal of gynaecological oncology. vol 21. issue 1. 2000-04-21. PMID:10726619. |
apoptosis and apoptosis-related proteins (fas, fas ligand, blc-2, p53) in lymphoid elements of human ovarian tumors. |
2000-04-21 |
2023-08-12 |
human |
H Ben-Hur, P Gurevich, M Huszar, A Ben-Arie, V Berman, Y Tendler, O Zinder, R Tchanishev, S Gershon, G Mor, Y Zaltsman, F Kohen, I Zusma. Apoptosis and apoptosis-related proteins (Fas, Fas ligand, Blc-2, p53) in lymphoid elements of human ovarian tumors. European journal of gynaecological oncology. vol 21. issue 1. 2000-04-21. PMID:10726619. |
thus, their expression of apoptosis-related proteins (arp - fas and fas ligand, bcl-2, p53) in lymphocytes and their apoptosis were analyzed immunohistochemically in ovarian tumors of different grades. |
2000-04-21 |
2023-08-12 |
human |
M N'cho, Z Brahm. Fas-mediated apoptosis in T cells involves the dephosphorylation of the retinoblastoma protein by type 1 protein phosphatases. Human immunology. vol 60. issue 12. 2000-04-20. PMID:10626732. |
apoptosis is triggered by a number of different stimuli including the activation of fas antigen, a member of the tnf family, by the fas ligand. |
2000-04-20 |
2023-08-12 |
Not clear |
T Siitonen, P Mäntymaa, M Säily, E Savolainen, P Koistine. Etoposide-induced apoptosis is not associated with the fas pathway in acute myeloblastic leukemia cells. Leukemia research. vol 24. issue 4. 2000-04-20. PMID:10713325. |
etoposide-induced apoptosis is not associated with the fas pathway in acute myeloblastic leukemia cells. |
2000-04-20 |
2023-08-12 |
Not clear |
T Siitonen, P Mäntymaa, M Säily, E Savolainen, P Koistine. Etoposide-induced apoptosis is not associated with the fas pathway in acute myeloblastic leukemia cells. Leukemia research. vol 24. issue 4. 2000-04-20. PMID:10713325. |
we investigated whether the fas pathway is involved in etoposide-induced apoptosis in acute myeloblastic leukemia (aml). |
2000-04-20 |
2023-08-12 |
Not clear |
T Siitonen, P Mäntymaa, M Säily, E Savolainen, P Koistine. Etoposide-induced apoptosis is not associated with the fas pathway in acute myeloblastic leukemia cells. Leukemia research. vol 24. issue 4. 2000-04-20. PMID:10713325. |
in conclusion, etoposide-induced apoptosis is not mediated by the fas pathway in aml. |
2000-04-20 |
2023-08-12 |
Not clear |
L P Eberl, O Valdenaire, V Saintgiorgio, J F Jeannin, L Juillerat-Jeannere. Endothelin receptor blockade potentiates FasL-induced apoptosis in rat colon carcinoma cells. International journal of cancer. vol 86. issue 2. 2000-04-20. PMID:10738244. |
these cells also express the fas(apo-1, cd95)/fasl system, but are resistant to fasl-induced apoptosis. |
2000-04-20 |
2023-08-12 |
rat |
L P Eberl, O Valdenaire, V Saintgiorgio, J F Jeannin, L Juillerat-Jeannere. Endothelin receptor blockade potentiates FasL-induced apoptosis in rat colon carcinoma cells. International journal of cancer. vol 86. issue 2. 2000-04-20. PMID:10738244. |
bosentan sensitization to fasl-induced apoptosis was not mediated by increased expression of fas receptor and was blocked by the caspase inhibitor zvad-fmk. |
2000-04-20 |
2023-08-12 |
rat |
B Abdulkarim, S Sabri, E Deutsch, S Vaganay, E Marangoni, W Vainchenker, P Bongrand, P Busson, J Bourhi. Radiation-induced expression of functional Fas ligand in EBV-positive human nasopharyngeal carcinoma cells. International journal of cancer. vol 86. issue 2. 2000-04-20. PMID:10738250. |
although fas and fas-l are essential determinants of apoptosis, few data support their role in the cytotoxic effect of ionizing radiation. |
2000-04-20 |
2023-08-12 |
human |
B Abdulkarim, S Sabri, E Deutsch, S Vaganay, E Marangoni, W Vainchenker, P Bongrand, P Busson, J Bourhi. Radiation-induced expression of functional Fas ligand in EBV-positive human nasopharyngeal carcinoma cells. International journal of cancer. vol 86. issue 2. 2000-04-20. PMID:10738250. |
both the fas receptor and the fas ligand were found to be functional in this model, and a high proportion of irradiated npc cells underwent apoptosis following tumor irradiation. |
2000-04-20 |
2023-08-12 |
human |
Y Ueno, M Ishii, K Yahagi, Y Mano, N Kisara, N Nakamura, T Shimosegawa, T Toyota, S Nagat. Fas-mediated cholangiopathy in the murine model of graft versus host disease. Hepatology (Baltimore, Md.). vol 31. issue 4. 2000-04-19. PMID:10733554. |
furthermore, the addition of agonistic fas antibody-(jo2)-induced cholangiocyte apoptosis confirmed by dna-ladder formation and annexin v staining. |
2000-04-19 |
2023-08-12 |
mouse |
Y Yang, Z Han, Z Cao, S Li, H Wang, W Li. [Effects of mifepristone on ICE expression and Fas expression in early pregnant chorionic villi]. Hua xi yi ke da xue xue bao = Journal of West China University of Medical Sciences = Huaxi yike daxue xuebao. vol 29. issue 2. 2000-04-14. PMID:10684020. |
these results suggest that mifepristone may terminate early pregnancy via increasing the expression of fas and promoting apoptosis in the chorionic villi. |
2000-04-14 |
2023-08-12 |
Not clear |