| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| T L Weigel, M T Lotze, P K Kim, A A Amoscato, J D Luketich, C Odou. Paclitaxel-induced apoptosis in non-small cell lung cancer cell lines is associated with increased caspase-3 activity. The Journal of thoracic and cardiovascular surgery. vol 119. issue 4 Pt 1. 2000-05-18. PMID:10733772. |
our objective was to determine whether paclitaxel-induced apoptosis in human lung cancer cells is fas dependent. |
2000-05-18 |
2023-08-12 |
human |
| C Servet-Delprat, P O Vidalain, O Azocar, F Le Deist, A Fischer, C Rabourdin-Comb. Consequences of Fas-mediated human dendritic cell apoptosis induced by measles virus. Journal of virology. vol 74. issue 9. 2000-05-18. PMID:10756053. |
in this study, human monocyte-derived dcs were used to demonstrate that dc apoptosis in mv-infected dc-t-cell cocultures is fas mediated, whereas apoptotic t cells could not be rescued by blocking the fas pathway. |
2000-05-18 |
2023-08-12 |
human |
| C Servet-Delprat, P O Vidalain, O Azocar, F Le Deist, A Fischer, C Rabourdin-Comb. Consequences of Fas-mediated human dendritic cell apoptosis induced by measles virus. Journal of virology. vol 74. issue 9. 2000-05-18. PMID:10756053. |
we conclude that the cd40 ligand expressed by activated t cells first enhances mv replication in dcs, and then fas ligand produced by activated t cells induces fas-mediated apoptosis of dcs, thus facilitating mv release. |
2000-05-18 |
2023-08-12 |
human |
| N Shinoura, Y Muramatsu, Y Yoshida, A Asai, T Kirino, H Hamad. Adenovirus-mediated transfer of caspase-3 with Fas ligand induces drastic apoptosis in U-373MG glioma cells. Experimental cell research. vol 256. issue 2. 2000-05-18. PMID:10772815. |
adenovirus-mediated transfer of caspase-3 with fas ligand induces drastic apoptosis in u-373mg glioma cells. |
2000-05-18 |
2023-08-12 |
Not clear |
| N Shinoura, Y Muramatsu, Y Yoshida, A Asai, T Kirino, H Hamad. Adenovirus-mediated transfer of caspase-3 with Fas ligand induces drastic apoptosis in U-373MG glioma cells. Experimental cell research. vol 256. issue 2. 2000-05-18. PMID:10772815. |
next, we investigated whether overexpression of caspase-3 could enhance fas ligand-mediated apoptosis in these four cell lines. |
2000-05-18 |
2023-08-12 |
Not clear |
| N Shinoura, Y Muramatsu, Y Yoshida, A Asai, T Kirino, H Hamad. Adenovirus-mediated transfer of caspase-3 with Fas ligand induces drastic apoptosis in U-373MG glioma cells. Experimental cell research. vol 256. issue 2. 2000-05-18. PMID:10772815. |
in u-373mg cells, which showed the highest level of expression of surface fas among the four cell lines, coinfection of the adv for caspase-3 (adv-caspase-3) and the adv for fas ligand (adv-fl) induced a remarkably increased degree of apoptosis compared with that induced by the single infection of either adv-caspase-3 or adv-fl. |
2000-05-18 |
2023-08-12 |
Not clear |
| S H Kaufmann, W C Earnsha. Induction of apoptosis by cancer chemotherapy. Experimental cell research. vol 256. issue 1. 2000-05-12. PMID:10739650. |
studies performed over the past five years have demonstrated that there are two major cell-intrinsic pathways for inducing apoptosis, one that begins with ligation of cell surface death receptors and another that involves mitochondrial release of cytochrome c. several reports have suggested that anticancer drugs kill susceptible cells by inducing expression of death receptor ligands, especially fas ligand (fasl). |
2000-05-12 |
2023-08-12 |
Not clear |
| N Hosaka, N Oyaizu, S Than, S Pahw. Correlation of loss of CD4 T cells with plasma levels of both soluble form Fas (CD95) Fas ligand (FasL) in HIV-infected infants. Clinical immunology (Orlando, Fla.). vol 95. issue 1 Pt 1. 2000-05-12. PMID:10794428. |
fas and fas ligand (fasl), members of the tnfr and tnf families of molecules involved in apoptosis, respectively, are expressed in membrane-associated as well as soluble forms. |
2000-05-12 |
2023-08-12 |
Not clear |
| N M Ravindranath, K Nishimoto, K Chu, C Shule. Cell-surface expression of complement restriction factors and sialyl Lewis antigens in oral carcinoma: relevance to chemo-immunotherapy. Anticancer research. vol 20. issue 1A. 2000-05-11. PMID:10769630. |
we have analyzed the expression of the tumor-associated sialyl lewisa (slea) and sialyl lewisx (slea) antigens, the complement restriction factors (cd59, cd46 and cd55) and the apoptosis associated factors fas and fas ligand. |
2000-05-11 |
2023-08-12 |
human |
| N M Ravindranath, K Nishimoto, K Chu, C Shule. Cell-surface expression of complement restriction factors and sialyl Lewis antigens in oral carcinoma: relevance to chemo-immunotherapy. Anticancer research. vol 20. issue 1A. 2000-05-11. PMID:10769630. |
the scc lines expressed very low levels of fas and fasl indicating that there maybe a lack of these signaling molecules for apoptosis. |
2000-05-11 |
2023-08-12 |
human |
| A Gewies, O W Rokhlin, M B Cohe. Cytochrome c is involved in Fas-mediated apoptosis of prostatic carcinoma cell lines. Cancer research. vol 60. issue 8. 2000-05-11. PMID:10786680. |
we have shown previously that the pathways leading to fas-mediated apoptosis in prostatic carcinoma cell lines are intact, because apoptosis can be triggered either by fas ligation alone in the fas-sensitive cell lines pc3 and alva31 or by rendering the fas-resistant cell lines du145 and jca1 fas-sensitive by combined treatment with anti-fas monoclonal antibody and cycloheximide (o. w. rokhlin et al., cancer res., 57: 1758-1768, 1997). |
2000-05-11 |
2023-08-12 |
Not clear |
| A Pickens, G Pan, J M McDonald, S M Vicker. Fas expression prevents cholangiocarcinoma tumor growth. Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract. vol 3. issue 4. 2000-05-10. PMID:10482689. |
fas/apo-1 (cd95) receptor and fas ligand have been implicated as key factors in apoptosis. |
2000-05-10 |
2023-08-12 |
mouse |
| A Pickens, G Pan, J M McDonald, S M Vicker. Fas expression prevents cholangiocarcinoma tumor growth. Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract. vol 3. issue 4. 2000-05-10. PMID:10482689. |
the purpose of this study was to evaluate the role of the fas receptor in the induction of apoptosis in cholangiocarcinoma and to assess the role of the fas receptor in cholangiocarcinoma tumorigenesis. |
2000-05-10 |
2023-08-12 |
mouse |
| A Pickens, G Pan, J M McDonald, S M Vicker. Fas expression prevents cholangiocarcinoma tumor growth. Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract. vol 3. issue 4. 2000-05-10. PMID:10482689. |
fas receptor expression is an important mediator of apoptosis in cultured human cholangiocarcinoma cells and appears to be a critical determinant of cholangiocarcinoma tumor growth in nude mice. |
2000-05-10 |
2023-08-12 |
mouse |
| E Hatano, C A Bradham, A Stark, Y Iimuro, J J Lemasters, D A Brenne. The mitochondrial permeability transition augments Fas-induced apoptosis in mouse hepatocytes. The Journal of biological chemistry. vol 275. issue 16. 2000-05-10. PMID:10766806. |
to clarify the differences between tumor necrosis factor alpha (tnfalpha) and fas pathways in hepatocyte apoptosis, primary mouse hepatocytes were treated with tnfalpha or an agonist anti-fas antibody after infection with an adenovirus expressing an ikappab superrepressor (ad5ikappab). |
2000-05-10 |
2023-08-12 |
mouse |
| E Hatano, C A Bradham, A Stark, Y Iimuro, J J Lemasters, D A Brenne. The mitochondrial permeability transition augments Fas-induced apoptosis in mouse hepatocytes. The Journal of biological chemistry. vol 275. issue 16. 2000-05-10. PMID:10766806. |
tnfalpha and fas recruit similar but nonidentical, pathways signaling apoptosis. |
2000-05-10 |
2023-08-12 |
mouse |
| P Doerfler, K A Forbush, R M Perlmutte. Caspase enzyme activity is not essential for apoptosis during thymocyte development. Journal of immunology (Baltimore, Md. : 1950). vol 164. issue 8. 2000-05-09. PMID:10754300. |
p35 expression inhibited fas (cd95)-, cd3-, or peptide-induced caspase activity in vitro and conferred resistance to fas-induced apoptosis. |
2000-05-09 |
2023-08-12 |
mouse |
| S Munakata, T Enomoto, M Tsujimoto, Y Otsuki, H Miwa, H Kanno, K Aozas. Expressions of Fas ligand and other apoptosis-related genes and their prognostic significance in epithelial ovarian neoplasms. British journal of cancer. vol 82. issue 8. 2000-05-09. PMID:10780525. |
these findings suggest that fas l expressing carcinomas induce apoptosis in infiltrating ctl with fas expression, and escape from immune surveillance. |
2000-05-09 |
2023-08-12 |
Not clear |
| N Nagarkatt. Tumor-derived Fas ligand induces toxicity in lymphoid organs and plays an important role in successful chemotherapy. Cancer immunology, immunotherapy : CII. vol 49. issue 1. 2000-05-09. PMID:10782865. |
recent studies have suggested that fas ligand (fasl-) tumor cells can induce apoptosis in fas+ t cells. |
2000-05-09 |
2023-08-12 |
mouse |
| J Zangrilli, N Robertson, A Shetty, J Wu, A Hastie, J E Fish, G Litwack, S P Peter. Effect of IL-5, glucocorticoid, and Fas ligation on Bcl-2 homologue expression and caspase activation in circulating human eosinophils. Clinical and experimental immunology. vol 120. issue 1. 2000-05-08. PMID:10759758. |
the effect of relevant inducers of eosinophil apoptosis (glucocorticoid and fas ligation) on these regulatory proteins was also examined. |
2000-05-08 |
2023-08-12 |
human |