| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S W Chan, L Hegyi, S Scott, N R Cary, P L Weissberg, M R Bennet. Sensitivity to Fas-mediated apoptosis is determined below receptor level in human vascular smooth muscle cells. Circulation research. vol 86. issue 10. 2000-06-20. PMID:10827133. |
although differences in surface fas expression can explain fas resistance, multiple proteins below receptor level also inhibit fas-induced apoptosis. |
2000-06-20 |
2023-08-12 |
human |
| S W Chan, L Hegyi, S Scott, N R Cary, P L Weissberg, M R Bennet. Sensitivity to Fas-mediated apoptosis is determined below receptor level in human vascular smooth muscle cells. Circulation research. vol 86. issue 10. 2000-06-20. PMID:10827133. |
to examine the mechanism of fas resistance, we studied fas-induced apoptosis in human medial vascular smooth muscle cells (vsmcs) from healthy coronary arteries. |
2000-06-20 |
2023-08-12 |
human |
| A Brás, J P Albar, E Leonardo, G G de Buitrago, C Martínez-. Ceramide-induced cell death is independent of the Fas/Fas ligand pathway and is prevented by Nur77 overexpression in A20 B cells. Cell death and differentiation. vol 7. issue 3. 2000-06-19. PMID:10745271. |
in conclusion, our results suggest that, in the a20 b cell line, fas and ceramide trigger two distinct pathways and that nur77 overexpression confers protection against ceramide-mediated apoptosis which correlates with inhibition of p53, bax and p27kip1 induction. |
2000-06-19 |
2023-08-12 |
Not clear |
| S Hatakeyama, N Tomichi, Y Ohara-Nemoto, M Sato. The immunohistochemical localization of Fas and Fas ligand in jaw bone and tooth germ of human fetuses. Calcified tissue international. vol 66. issue 5. 2000-06-19. PMID:10773101. |
the induction of apoptosis observed in monocytes seems to be caused via a fas-fas ligand cell death system, because some of these monocytes were fas-positive, and most of them were fas ligand-positive. |
2000-06-19 |
2023-08-12 |
human |
| A Nasir, H S Arora, H E Kaise. Apoptosis and pathogenesis of viral hepatitis C--an update. In vivo (Athens, Greece). vol 14. issue 1. 2000-06-16. PMID:10757089. |
apoptosis occurs both in acute or chronic hepatitis and has been suggested to be mediated through fas antigen. |
2000-06-16 |
2023-08-12 |
Not clear |
| S Takasaki, K Hayashida, C Morita, H Ishibashi, Y Nih. CD56 directly interacts in the process of NCAM-positive target cell-killing by NK cells. Cell biology international. vol 24. issue 2. 2000-06-14. PMID:10772769. |
since neither fas antigen expression nor apoptotic changes were induced by addition to a mixed culture supernatant of nk and target cells, both the fas-fas ligand system and soluble factors do not seem to participate in apoptosis in these circumstances. |
2000-06-14 |
2023-08-12 |
Not clear |
| T Lamy, F A Bauer, J H Liu, Y X Li, E Pillemer, H Shahidi, S A Gregory, R Zambello, R Marcolongo, G Semenzato, T P Loughra. Clinicopathological features of aggressive large granular lymphocyte leukaemia resemble Fas ligand transgenic mice. British journal of haematology. vol 108. issue 4. 2000-06-14. PMID:10792274. |
apoptosis of lung and liver tissue is seen in fas ligand transgenic mice. |
2000-06-14 |
2023-08-12 |
mouse |
| K M Kurrelmeyer, L H Michael, G Baumgarten, G E Taffet, J J Peschon, N Sivasubramanian, M L Entman, D L Man. Endogenous tumor necrosis factor protects the adult cardiac myocyte against ischemic-induced apoptosis in a murine model of acute myocardial infarction. Proceedings of the National Academy of Sciences of the United States of America. vol 97. issue 10. 2000-06-13. PMID:10779546. |
the increase in apoptosis in the tnfr1/tnfr2-deficient mice did not appear to be secondary to a selective up-regulation of the fas ligand/receptor system in these mice. |
2000-06-13 |
2023-08-12 |
mouse |
| U Ramenghi, S Bonissoni, G Migliaretti, S DeFranco, F Bottarel, C Gambaruto, D DiFranco, R Priori, F Conti, I Dianzani, G Valesini, F Merletti, U Dianzan. Deficiency of the Fas apoptosis pathway without Fas gene mutations is a familial trait predisposing to development of autoimmune diseases and cancer. Blood. vol 95. issue 10. 2000-06-13. PMID:10807785. |
deficiency of the fas apoptosis pathway without fas gene mutations is a familial trait predisposing to development of autoimmune diseases and cancer. |
2000-06-13 |
2023-08-12 |
human |
| J H Liu, S Wei, T Lamy, P K Epling-Burnette, G Starkebaum, J Y Djeu, T P Loughra. Chronic neutropenia mediated by fas ligand. Blood. vol 95. issue 10. 2000-06-13. PMID:10807792. |
serum from the patients triggered apoptosis of normal neutrophils that depended partly on the fas pathway. |
2000-06-13 |
2023-08-12 |
human |
| N R Lewis, M Pallis, N H Russel. Fas receptor-Fas ligand system is independent of both CD34 status and chemosensitivity in acute myeloid leukemia. Experimental hematology. vol 28. issue 5. 2000-06-13. PMID:10812243. |
to determine whether the fas receptor-fas ligand (fasr-fasl) system, which triggers apoptosis in sensitive cells, is an important mechanism of cytotoxicity in acute myeloblastic leukemia (aml). |
2000-06-13 |
2023-08-12 |
Not clear |
| I Petak, D M Tillman, F G Harwood, R Mihalik, J A Houghto. Fas-dependent and -independent mechanisms of cell death following DNA damage in human colon carcinoma cells. Cancer research. vol 60. issue 10. 2000-06-13. PMID:10825136. |
a close correlation was found between acute induction of apoptosis (24 h) and up-regulated expression of fasl at high concentrations of each of the three agents (0.3-3 microm doxorubicin, 0.3-3 microm topotecan, and 10-90 microm vp-16), which was caspase dependent but fas independent. |
2000-06-13 |
2023-08-12 |
human |
| B Ke, A J Coito, H Kato, Y Zhai, T Wang, B Sawitzki, P Seu, R W Busuttil, J W Kupiec-Weglinsk. Fas ligand gene transfer prolongs rat renal allograft survival and down-regulates anti-apoptotic Bag-1 in parallel with enhanced Th2-type cytokine expression. Transplantation. vol 69. issue 8. 2000-06-13. PMID:10836382. |
fas ligand (fasl) induces apoptosis of cells bearing fas receptor, and may play a role in the acquisition of immune privilege. |
2000-06-13 |
2023-08-12 |
rat |
| A P Costa-Pereira, S L McKenna, T G Cotte. Activation of SAPK/JNK by camptothecin sensitizes androgen-independent prostate cancer cells to Fas-induced apoptosis. British journal of cancer. vol 82. issue 11. 2000-06-13. PMID:10839298. |
we have previously shown that the androgen-independent prostate cancer cells du145, despite expressing fas and fasl, were resistant to anti-fas-induced apoptosis, and that this resistance could be overcome by pretreating the cells with sublethal doses of camptothecin. |
2000-06-13 |
2023-08-12 |
Not clear |
| E R Cameron, J Morton, C J Johnston, J Irvine, M Bell, D E Onions, J C Neil, M Campbell, K Blyt. Fas-independent apoptosis in T-cell tumours induced by the CD2-myc transgene. Cell death and differentiation. vol 7. issue 1. 2000-06-12. PMID:10713723. |
the pathways by which myc induces apoptosis are as yet poorly characterised although recent observations on rat fibroblasts over-expressing myc have demonstrated a requirement for the fas pathway. |
2000-06-12 |
2023-08-12 |
mouse |
| E R Cameron, J Morton, C J Johnston, J Irvine, M Bell, D E Onions, J C Neil, M Campbell, K Blyt. Fas-independent apoptosis in T-cell tumours induced by the CD2-myc transgene. Cell death and differentiation. vol 7. issue 1. 2000-06-12. PMID:10713723. |
these results show that activation of c-myc and loss of fas do not collaborate in t lymphoma development and that myc-induced apoptosis in t-cells occurs by fas-independent pathways. |
2000-06-12 |
2023-08-12 |
mouse |
| M H Al-Maini, J D Mountz, H A Al-Mohri, E M El-Ageb, B M Al-Riyami, K L Svenson, T Zhou, E R Richen. Serum levels of soluble Fas correlate with indices of organ damage in systemic lupus erythematosus. Lupus. vol 9. issue 2. 2000-06-08. PMID:10787011. |
to evaluate whether the levels of soluble form of the fas apoptosis antigen (scd95/sfas) varied from those of healthy control subjects in a group of patients with systemic lupus erythematosus (sle). |
2000-06-08 |
2023-08-12 |
human |
| T Tatsuta, A Shiraishi, J D Mount. The prodomain of caspase-1 enhances Fas-mediated apoptosis through facilitation of caspase-8 activation. The Journal of biological chemistry. vol 275. issue 19. 2000-06-08. PMID:10799503. |
expression of recombinant pro-c1 in hela cells enhanced apoptosis mediated by fas, but not etoposide-induced apoptosis. |
2000-06-08 |
2023-08-12 |
Not clear |
| M D Josephs, F R Bahjat, K Fukuzuka, R Ksontini, C C Solorzano, C K Edwards, C L Tannahill, S L MacKay, E M Copeland, L L Moldawe. Lipopolysaccharide and D-galactosamine-induced hepatic injury is mediated by TNF-alpha and not by Fas ligand. American journal of physiology. Regulatory, integrative and comparative physiology. vol 278. issue 5. 2000-06-08. PMID:10801287. |
tumor necrosis factor (tnf)-alpha and fas ligand (fasl) are trimeric proteins that induce apoptosis through similar caspase-dependent pathways. |
2000-06-08 |
2023-08-12 |
mouse |
| S M Kang, D Braat, D B Schneider, R W O'Rourke, Z Lin, N L Ascher, D A Dichek, S Baekkeskov, P G Stoc. A non-cleavable mutant of Fas ligand does not prevent neutrophilic destruction of islet transplants. Transplantation. vol 69. issue 9. 2000-06-08. PMID:10830216. |
fas ligand (fasl) mediates apoptosis of susceptible fas-expressing lymphocytes, and may contribute to the maintenance of peripheral tolerance. |
2000-06-08 |
2023-08-12 |
Not clear |