| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S E Turvey, V Gonzalez-Nicolini, C I Kingsley, A T Larregina, P J Morris, M G Castro, P R Lowenstein, K J Woo. Fas ligand-transfected myoblasts and islet cell transplantation. Transplantation. vol 69. issue 9. 2000-06-08. PMID:10830245. |
expression of fas ligand (fasl, cd95l) within the local environment of an allograft may protect from rejection by inducing apoptosis of infiltrating t cells. |
2000-06-08 |
2023-08-12 |
Not clear |
| A Gewies, O W Rokhlin, M B Cohe. Ceramide induces cell death in the human prostatic carcinoma cell lines PC3 and DU145 but does not seem to be involved in Fas-mediated apoptosis. Laboratory investigation; a journal of technical methods and pathology. vol 80. issue 5. 2000-06-08. PMID:10830777. |
treatment of cells with synthetic c2-ceramide has been reported to induce apoptosis in several cell systems, and endogenously formed ceramide has been proposed to act as a second messenger, activating signaling pathways which contribute to the execution of apoptotic cell death after fas ligation or tumor necrosis factor receptor-1 ligation. |
2000-06-08 |
2023-08-12 |
human |
| A Gewies, O W Rokhlin, M B Cohe. Ceramide induces cell death in the human prostatic carcinoma cell lines PC3 and DU145 but does not seem to be involved in Fas-mediated apoptosis. Laboratory investigation; a journal of technical methods and pathology. vol 80. issue 5. 2000-06-08. PMID:10830777. |
we conclude that sphingomyelinase-generated ceramide does not play a role in fas-mediated apoptosis in pc3, and that there are fundamental differences in the mechanisms of cell death induced by c2-ceramide and fas ligation. |
2000-06-08 |
2023-08-12 |
human |
| Y Murayama, K Terao, M Inoue-Murayam. Molecular cloning and characterization of cynomolgus monkey Fas. Human immunology. vol 61. issue 5. 2000-06-07. PMID:10773350. |
an agonistic fas antibody (ch11) or cynomolgus fasl induced apoptosis in human fas-transfected k562 cells in the presence of chx but not in the cynomolgus fas transfectant. |
2000-06-07 |
2023-08-12 |
human |
| Y Murayama, K Terao, M Inoue-Murayam. Molecular cloning and characterization of cynomolgus monkey Fas. Human immunology. vol 61. issue 5. 2000-06-07. PMID:10773350. |
ch11 and fasl failed to trigger apoptosis in the transfectant expressing human-cynomolgus chimera fas consisting mostly of human-derived extracellular region and cynomolgus-derived intracellular portion. |
2000-06-07 |
2023-08-12 |
human |
| Y Murayama, K Terao, M Inoue-Murayam. Molecular cloning and characterization of cynomolgus monkey Fas. Human immunology. vol 61. issue 5. 2000-06-07. PMID:10773350. |
on the other hand, the transfectant expressing cynomolgus-human chimera fas with human-derived intracellular region underwent apoptosis upon exposure to fasl. |
2000-06-07 |
2023-08-12 |
human |
| N Favre-Felix, A Fromentin, A Hammann, E Solary, F Martin, B Bonnott. Cutting edge: the tumor counterattack hypothesis revisited: colon cancer cells do not induce T cell apoptosis via the Fas (CD95, APO-1) pathway. Journal of immunology (Baltimore, Md. : 1950). vol 164. issue 10. 2000-06-07. PMID:10799856. |
cutting edge: the tumor counterattack hypothesis revisited: colon cancer cells do not induce t cell apoptosis via the fas (cd95, apo-1) pathway. |
2000-06-07 |
2023-08-12 |
human |
| F Somma, L Tuosto, M S Gilardini Montani, M M Di Somma, E Cundari, E Piccolell. Engagement of CD4 before TCR triggering regulates both Bax- and Fas (CD95)-mediated apoptosis. Journal of immunology (Baltimore, Md. : 1950). vol 164. issue 10. 2000-06-07. PMID:10799864. |
engagement of cd4 before tcr triggering regulates both bax- and fas (cd95)-mediated apoptosis. |
2000-06-07 |
2023-08-12 |
Not clear |
| K Nagaraju, L Casciola-Rosen, A Rosen, C Thompson, L Loeffler, T Parker, C Danning, P J Rochon, J Gillespie, P Plot. The inhibition of apoptosis in myositis and in normal muscle cells. Journal of immunology (Baltimore, Md. : 1950). vol 164. issue 10. 2000-06-07. PMID:10799913. |
the expression of both fas and fasl in the inflamed tissue makes the absence of apoptosis more striking. |
2000-06-07 |
2023-08-12 |
human |
| J Zhang, K Miranda, B Y Ma, A Fin. Molecular characterization of the mouse Fas ligand promoter in airway epithelial cells. Biochimica et biophysica acta. vol 1490. issue 3. 2000-06-06. PMID:10684974. |
constitutively expressed fas ligand in several distinct epithelial cell types appears to protect tissues by inducing apoptosis of fas(+) immune cells during inflammatory reactions. |
2000-06-06 |
2023-08-12 |
mouse |
| M Kawasaki, K Kuwano, Y Nakanishi, N Hagimoto, K Takayama, X H Pei, T Maeyama, M Yoshimi, N Har. Analysis of Fas and Fas ligand expression and function in lung cancer cell lines. European journal of cancer (Oxford, England : 1990). vol 36. issue 5. 2000-06-06. PMID:10738132. |
immunoblotting, rt-pcr and flow cytometric analyses were carried out to measure the expression of fas and fasl and to examine their interactions and effects on cell growth and apoptosis. |
2000-06-06 |
2023-08-12 |
Not clear |
| M Kawasaki, K Kuwano, Y Nakanishi, N Hagimoto, K Takayama, X H Pei, T Maeyama, M Yoshimi, N Har. Analysis of Fas and Fas ligand expression and function in lung cancer cell lines. European journal of cancer (Oxford, England : 1990). vol 36. issue 5. 2000-06-06. PMID:10738132. |
apoptosis induced by the agonistic anti-fas antibody was significantly correlated with fas expression (p=0.0075), whereas cisplatin-induced apoptosis was not. |
2000-06-06 |
2023-08-12 |
Not clear |
| M Kawasaki, K Kuwano, Y Nakanishi, N Hagimoto, K Takayama, X H Pei, T Maeyama, M Yoshimi, N Har. Analysis of Fas and Fas ligand expression and function in lung cancer cell lines. European journal of cancer (Oxford, England : 1990). vol 36. issue 5. 2000-06-06. PMID:10738132. |
thus, our data indicated that fas and fasl were co-expressed in lung cancer cell lines, and that fas ligation induced by agonistic anti-fas antibody is functional and induced apoptosis that was dependent on the levels of fas expression. |
2000-06-06 |
2023-08-12 |
Not clear |
| Y Higami, I Shimokawa, K Ando, K Tanaka, T Tsuchiy. Dietary restriction reduces hepatocyte proliferation and enhances p53 expression but does not increase apoptosis in normal rats during development. Cell and tissue research. vol 299. issue 3. 2000-06-06. PMID:10772250. |
we examined the effects of dr on proliferation and apoptosis of hepatocytes during development and explained these changes subcellularly using immunohistochemistry for bromodeoxyuridine (brdu) incorporation, proliferating cell nuclear antigen (pcna) and p53, terminal dutp nick end labeling (tunel) and quantitative reverse transcription-polymerase chain reaction (rt-pcr) for tgfalpha, tgfbeta1, p53, fas and tnf receptor (tnfr). |
2000-06-06 |
2023-08-12 |
rat |
| Y Higami, I Shimokawa, K Ando, K Tanaka, T Tsuchiy. Dietary restriction reduces hepatocyte proliferation and enhances p53 expression but does not increase apoptosis in normal rats during development. Cell and tissue research. vol 299. issue 3. 2000-06-06. PMID:10772250. |
while dr accelerates the expression of fas antigen, this result does not influence the rate of apoptosis of hepatocytes under physiological conditions. |
2000-06-06 |
2023-08-12 |
rat |
| R Tsunoda, E Heinen, N Suga. Follicular dendritic cells in vitro modulate the expression of Fas and Bcl-2 on germinal center B cells. Cell and tissue research. vol 299. issue 3. 2000-06-06. PMID:10772253. |
b cells nonentrapped by fdc decreased rapidly in number owing to early apoptosis in vitro, whereas entrapped b cells were rescued for at least 18 h and showed peculiar regulation of fas and bcl-2. |
2000-06-06 |
2023-08-12 |
Not clear |
| N Ishimaru, T Yoneda, K Saegusa, K Yanagi, N Haneji, K Moriyama, I Saito, Y Hayash. Severe destructive autoimmune lesions with aging in murine Sjögren's syndrome through Fas-mediated apoptosis. The American journal of pathology. vol 156. issue 5. 2000-06-02. PMID:10793067. |
in addition, a decrease in fas expression was found on splenic cd4(+) t cells in the aged mice, and anti-fas mab-stimulated apoptosis was down-regulated on cd4(+) t cells. |
2000-06-02 |
2023-08-12 |
mouse |
| C Sergi, P Kahl, H F Ott. Contribution of apoptosis and apoptosis-related proteins to the malformation of the primitive intrahepatic biliary system in Meckel syndrome. The American journal of pathology. vol 156. issue 5. 2000-06-02. PMID:10793071. |
the expression of two apoptosis-related proteins, fas (a transmembrane cell surface protein involved in the apoptosis) and bcl-2 (an anti-apoptotic protein), was studied by immunohistochemistry in the liver of 11 normal fetuses of different gestational ages (14-40 weeks of gestation) and in 40 fetuses with meckel syndrome (16-38 weeks of gestation). |
2000-06-02 |
2023-08-12 |
Not clear |
| S A Renshaw, S J Timmons, V Eaton, L R Usher, M Akil, C D Bingle, M K Whyt. Inflammatory neutrophils retain susceptibility to apoptosis mediated via the Fas death receptor. Journal of leukocyte biology. vol 67. issue 5. 2000-06-01. PMID:10811006. |
inflammatory neutrophils retain susceptibility to apoptosis mediated via the fas death receptor. |
2000-06-01 |
2023-08-12 |
Not clear |
| S A Renshaw, S J Timmons, V Eaton, L R Usher, M Akil, C D Bingle, M K Whyt. Inflammatory neutrophils retain susceptibility to apoptosis mediated via the Fas death receptor. Journal of leukocyte biology. vol 67. issue 5. 2000-06-01. PMID:10811006. |
inflammatory neutrophils underwent constitutive apoptosis in culture more rapidly than peripheral blood neutrophils; this was not explained by changes in surface expression of fas or by induction of fas ligand. |
2000-06-01 |
2023-08-12 |
Not clear |