Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
V N Ivanov, Z Rona. p38 protects human melanoma cells from UV-induced apoptosis through down-regulation of NF-kappaB activity and Fas expression. Oncogene. vol 19. issue 26. 2000-07-12. PMID:10871852. |
forced expression of a dominant negative form of p38 (p38-asp) or treatment with p38 pharmacological inhibitor, sb203580, increases nf-kappab activity, fas expression and the levels of uvc-induced apoptosis in late stage melanoma cells. |
2000-07-12 |
2023-08-12 |
human |
V N Ivanov, Z Rona. p38 protects human melanoma cells from UV-induced apoptosis through down-regulation of NF-kappaB activity and Fas expression. Oncogene. vol 19. issue 26. 2000-07-12. PMID:10871852. |
identifying p38-mediated down-regulation of fas expression illustrates a novel regulatory pathway by which ask1/mkk6/p38 alters the degree and nature of the uv-induced apoptosis of melanoma cells. |
2000-07-12 |
2023-08-12 |
human |
G Wohlleben, S M Ibrahim, J Schmidt, K V Toyka, H P Hartung, R Gol. Regulation of Fas and FasL expression on rat Schwann cells. Glia. vol 30. issue 4. 2000-07-07. PMID:10797617. |
to assess the possible involvement of the fas/fasl system in t-cell apoptosis in the pns of the rat, we characterized fas and fasl expression on neonatal rat schwann cells (sc) in vitro. |
2000-07-07 |
2023-08-12 |
human |
D W Guan, T Ohshima, T Kond. Immunohistochemical study on Fas and Fas ligand in skin wound healing. The Histochemical journal. vol 32. issue 2. 2000-07-06. PMID:10816072. |
an immunohistochemical study on the expression of fas and fas ligand (fas l) was performed in order to examine the role of apoptosis through fas-fas l in mouse skin wound healing. |
2000-07-06 |
2023-08-12 |
mouse |
D W Guan, T Ohshima, T Kond. Immunohistochemical study on Fas and Fas ligand in skin wound healing. The Histochemical journal. vol 32. issue 2. 2000-07-06. PMID:10816072. |
these results indicate that apoptosis through fas and fas l may play an important role for reducing the cellularity during skin wound healing in mice. |
2000-07-06 |
2023-08-12 |
mouse |
R W Georgantas, K W Leong, J T Augus. Antigen-specific induction of peripheral T cell tolerance in vivo by codelivery of DNA vectors encoding antigen and Fas ligand. Human gene therapy. vol 11. issue 6. 2000-06-30. PMID:10779162. |
fas ligand (fasl, cd95l) induces apoptosis in activated t cells with upregulated fas (cd95) expression through the process termed activation-induced cell death (aicd). |
2000-06-30 |
2023-08-12 |
mouse |
X X Wu, Y Mizutani, Y Kakehi, O Yoshida, O Ogaw. Enhancement of Fas-mediated apoptosis in renal cell carcinoma cells by adriamycin. Cancer research. vol 60. issue 11. 2000-06-30. PMID:10850437. |
several anticancer agents also mediate apoptosis and may share common intracellular pathways leading to apoptosis with fas. |
2000-06-30 |
2023-08-12 |
human |
A K Singh, H Mani, P Seth, J P Gaddipati, R Kumari, K K Banuadha, S C Sharma, D K Kulshreshtha, R K Maheshwar. Picroliv preconditioning protects the rat liver against ischemia-reperfusion injury. European journal of pharmacology. vol 395. issue 3. 2000-06-29. PMID:10812054. |
reduction in apoptosis was associated with decreased mrna expression of caspase-3 and fas. |
2000-06-29 |
2023-08-12 |
rat |
S C Posey, M P Martelli, T Azuma, D J Kwiatkowski, B E Biere. Failure of gelsolin overexpression to regulate lymphocyte apoptosis. Blood. vol 95. issue 11. 2000-06-29. PMID:10828033. |
in contrast to previous reports, overexpression of gelsolin in jurkat t cells did not prevent or delay apoptosis induced by fas ligation or ceramide treatment. |
2000-06-29 |
2023-08-12 |
Not clear |
K A Kirou, R K Vakkalanka, M J Butler, M K Cro. Induction of Fas ligand-mediated apoptosis by interferon-alpha. Clinical immunology (Orlando, Fla.). vol 95. issue 3. 2000-06-29. PMID:10866129. |
induction of fas ligand-mediated apoptosis by interferon-alpha. |
2000-06-29 |
2023-08-12 |
Not clear |
Y Yamada, K Sugahara, K Tsuruda, K Nohda, N Mori, T Hata, T Maeda, T Hayashibara, T Joh, M Honda, M Tawara, M Tomonaga, Y Miyazaki, S Kamihir. Lactacystin activates FLICE (caspase 8) protease and induces apoptosis in Fas-resistant adult T-cell leukemia cell lines. European journal of haematology. vol 64. issue 5. 2000-06-27. PMID:10863977. |
lc completely inhibited proteasome function as determined by a peptidyl-mca substrate (llvy-mca and lle-mca), and induced apoptosis in these cell lines irrespective of fas sensitivity at low concentrations (approximately 10 microm). |
2000-06-27 |
2023-08-12 |
Not clear |
C A White, K B Nguyen, M P Pende. B cell apoptosis in the central nervous system in experimental autoimmune encephalomyelitis: roles of B cell CD95, CD95L and Bcl-2 expression. Journal of autoimmunity. vol 14. issue 3. 2000-06-26. PMID:10756081. |
three colour flow cytometry indicated that b cells expressing cd95 (fas) or cd95 ligand (cd95l) were highly vulnerable to apoptosis, whereas b cells expressing bcl-2 were relatively protected from apoptosis. |
2000-06-26 |
2023-08-12 |
rat |
Y S Kim, K H Kim, J A Choi, J H Lee, H K Kim, N H Won, I Ki. Fas (APO-1/CD95) ligand and Fas expression in renal cell carcinomas: correlation with the prognostic factors. Archives of pathology & laboratory medicine. vol 124. issue 5. 2000-06-26. PMID:10782148. |
it is important to understand fasl and fas expression in tumors, because the growth of cancer might be controlled by fas-mediated apoptosis. |
2000-06-26 |
2023-08-12 |
Not clear |
J M Wu, B Wu, F Guarnieri, J T August, D B Drachma. Targeting antigen-specific T cells by genetically engineered antigen presenting cells. A strategy for specific immunotherapy of autoimmune disease. Journal of neuroimmunology. vol 106. issue 1-2. 2000-06-26. PMID:10814792. |
fas ligand, or antibody to fas, abrogated the t cell response, by inducing apoptosis of the apc-stimulated t cells. |
2000-06-26 |
2023-08-12 |
mouse |
T Kohji, Y Matsumot. Coexpression of Fas/FasL and Bax on brain and infiltrating T cells in the central nervous system is closely associated with apoptotic cell death during autoimmune encephalomyelitis. Journal of neuroimmunology. vol 106. issue 1-2. 2000-06-26. PMID:10814794. |
to elucidate the molecular mechanism of apoptosis of infiltrating t and other cells occurring in the cns during autoimmune encephalomyelitis, we determined the type of apoptotic cells and the localization of apoptosis-related molecules (fas, fasl, bax, bcl-2 and active caspase 3) by immunohistochemistry. |
2000-06-26 |
2023-08-12 |
Not clear |
M F Tsan, J E White, J G Maheshwari, T A Bremner, J Sacc. Resveratrol induces Fas signalling-independent apoptosis in THP-1 human monocytic leukaemia cells. British journal of haematology. vol 109. issue 2. 2000-06-26. PMID:10848832. |
resveratrol induces fas signalling-independent apoptosis in thp-1 human monocytic leukaemia cells. |
2000-06-26 |
2023-08-12 |
human |
S Y Han, S Y Choung, I S Paik, H J Kang, Y H Choi, S J Kim, M O Le. Activation of NF-kappaB determines the sensitivity of human colon cancer cells to TNFalpha-induced apoptosis. Biological & pharmaceutical bulletin. vol 23. issue 4. 2000-06-21. PMID:10784420. |
transcriptional expression of tnfr1(p55), as well as that of flice, fas, fadd, dr3, faf, tradd, and rip was similar in these cell lines, indicating that the susceptibility to tnfalpha-induced apoptosis may not be determined by the constitutive expression level of these factors. |
2000-06-21 |
2023-08-12 |
human |
Y Laouar, F Vasseur, G Moreau, C Garcia, V Pasqualetto, A C Waché, S Ezin. Selective involvement of the Fas (CD95)/Fas ligand pathway in bone marrow B cell progenitors. European journal of immunology. vol 30. issue 5. 2000-06-21. PMID:10820387. |
the fas / fas ligand (fasl) pathway has been implicated in apoptosis of various cell types. |
2000-06-21 |
2023-08-12 |
mouse |
Q Li, K Tsuruda, K Sugahara, N Dateki, E Ohishi, Y Yamada, M Tomonaga, H Moriuchi, Y Tsuji, S Kamihir. Qualitative and quantitative characterization of Fas (CD95) expression and its role in primary human acute leukemia cells. Leukemia research. vol 24. issue 5. 2000-06-20. PMID:10785266. |
fas antigen, a cell surface molecule, directly mediates apoptosis, and is expressed on a limited number of human tissues. |
2000-06-20 |
2023-08-12 |
human |
S W Chan, L Hegyi, S Scott, N R Cary, P L Weissberg, M R Bennet. Sensitivity to Fas-mediated apoptosis is determined below receptor level in human vascular smooth muscle cells. Circulation research. vol 86. issue 10. 2000-06-20. PMID:10827133. |
despite fas expression, many cells resist fas-induced apoptosis. |
2000-06-20 |
2023-08-12 |
human |