| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| L Maiuri, C Ciacci, V Raia, L Vacca, I Ricciardelli, F Raimondi, S Auricchio, S Quaratino, M Londe. FAS engagement drives apoptosis of enterocytes of coeliac patients. Gut. vol 48. issue 3. 2001-04-12. PMID:11171836. |
villus atrophy is the most distinctive sign of untreated coeliac disease (cd) and epithelial apoptosis is considered to be involved in this stage of the coeliac lesion. |
2001-04-12 |
2023-08-12 |
Not clear |
| S L Costa, E Paillaud, C Fages, C Rochette-Egly, J L Plassat, H Jouault, A Perzelova, M Tard. Effects of a novel synthetic retinoid on malignant glioma in vitro: inhibition of cell proliferation, induction of apoptosis and differentiation. European journal of cancer (Oxford, England : 1990). vol 37. issue 4. 2001-04-12. PMID:11267863. |
cd 437 also induced apoptosis in these cells, with 8mg-ba being the most sensitive. |
2001-04-12 |
2023-08-12 |
human |
| H M Shen, S Y Dong, C N On. Critical role of calcium overloading in cadmium-induced apoptosis in mouse thymocytes. Toxicology and applied pharmacology. vol 171. issue 1. 2001-03-22. PMID:11181107. |
the results showed that cd was able to cause apoptosis in mouse thymocytes in a time- and dose-dependent manner. |
2001-03-22 |
2023-08-12 |
mouse |
| M Shibutani, K Mitsumori, N Niho, S Satoh, H Hiratsuka, M Satoh, M Sumiyoshi, M Nishijima, Y Katsuki, J Suzuki, J Nakagawa, M And. Assessment of renal toxicity by analysis of regeneration of tubular epithelium in rats given low-dose cadmium chloride or cadmium-polluted rice for 22 months. Archives of toxicology. vol 74. issue 10. 2001-03-22. PMID:11201662. |
in experiment 2, levels of cdcl2 of 200 ppm or more clearly induced degeneration and apoptosis of proximal tubules with high correlations between renal cd levels, pcna li, and the severity of tubular degeneration. |
2001-03-22 |
2023-08-12 |
rat |
| H J Welkoborsky, J Gosepath, R Jacob, W J Mann, R G Amede. Biologic characteristics of paragangliomas of the nasal cavity and paranasal sinuses. American journal of rhinology. vol 14. issue 6. 2001-03-08. PMID:11197119. |
operative specimens of three patients who underwent surgery for a paraganglioma of the nasal cavity (one case) or paranasal sinuses (two cases) were investigated by routine histology, quantitative dna analysis, and immunohistochemical assessment of proliferation markers (i.e., proliferating cell nuclear antigen, pcna; ki67-mib-1), the expression of cell-surface antigens, which reflect the tumor-stroma interaction (i.e., cd 44 v0.4/5 and 6, cd 54, cd 106), oncogene products (nm-23; p53), and bcl-2 as a marker of apoptosis. |
2001-03-08 |
2023-08-12 |
Not clear |
| S H Jeong, S S Habeebu, C D Klaasse. Cadmium decreases gap junctional intercellular communication in mouse liver. Toxicological sciences : an official journal of the Society of Toxicology. vol 57. issue 1. 2000-10-13. PMID:10966522. |
cd disrupts cellular homeostasis in the liver through its induction of necrosis, apoptosis, and cellular proliferation. |
2000-10-13 |
2023-08-12 |
mouse |
| S H Jeong, S S Habeebu, C D Klaasse. Cadmium decreases gap junctional intercellular communication in mouse liver. Toxicological sciences : an official journal of the Society of Toxicology. vol 57. issue 1. 2000-10-13. PMID:10966522. |
this study investigates cd-induced alterations in gjic, cx32, and cx26 expression, and in cytoskeletal actin, and relates the changes to apoptosis and cell proliferation induced by cd in vivo. |
2000-10-13 |
2023-08-12 |
mouse |
| Y Liu, J Liu, S M Habeebu, M P Waalkes, C D Klaasse. Metallothionein-I/II null mice are sensitive to chronic oral cadmium-induced nephrotoxicity. Toxicological sciences : an official journal of the Society of Toxicology. vol 57. issue 1. 2000-10-13. PMID:10966523. |
six months of cd exposure to mt-null animals resulted in greater increases in renal caspase-3 activity, an indicator of apoptosis, than to wt mice. |
2000-10-13 |
2023-08-12 |
mouse |
| Y Yamazaki, M Tsuruga, D Zhou, Y Fujita, X Shang, Y Dang, K Kawasaki, S Ok. Cytoskeletal disruption accelerates caspase-3 activation and alters the intracellular membrane reorganization in DNA damage-induced apoptosis. Experimental cell research. vol 259. issue 1. 2000-09-20. PMID:10942579. |
in actinomycin d (ad)-induced apoptosis, caspase-3 activation and dna cleavage in human megakaryoblastic leukemia cmk-7 cells were greatly accelerated by tubulin and actin polymerization inhibitors [e.g., colcemid (cl) and cytochalasin d (cd), respectively], but the acceleration was not found with taxol or phalloidin. |
2000-09-20 |
2023-08-12 |
human |
| S M Chuang, I C Wang, J L Yan. Roles of JNK, p38 and ERK mitogen-activated protein kinases in the growth inhibition and apoptosis induced by cadmium. Carcinogenesis. vol 21. issue 7. 2000-08-17. PMID:10874022. |
cadmium (cd), a human carcinogen, can induce apoptosis in various cell types. |
2000-08-17 |
2023-08-12 |
human |
| S M Chuang, I C Wang, J L Yan. Roles of JNK, p38 and ERK mitogen-activated protein kinases in the growth inhibition and apoptosis induced by cadmium. Carcinogenesis. vol 21. issue 7. 2000-08-17. PMID:10874022. |
in this study we explore the ability of cd to activate jnk, p38 and erk, including their effects on cd-mediated growth inhibition and apoptosis in a human non-small cell lung carcinoma cell line, cl3. |
2000-08-17 |
2023-08-12 |
human |
| S M Chuang, I C Wang, J L Yan. Roles of JNK, p38 and ERK mitogen-activated protein kinases in the growth inhibition and apoptosis induced by cadmium. Carcinogenesis. vol 21. issue 7. 2000-08-17. PMID:10874022. |
pd98059, an inhibitor of erk upstream activators mapk kinase (mkk) 1 and mkk2, greatly enhanced cytotoxicity and apoptosis in cells treated with low cd doses. |
2000-08-17 |
2023-08-12 |
human |
| S M Chuang, I C Wang, J L Yan. Roles of JNK, p38 and ERK mitogen-activated protein kinases in the growth inhibition and apoptosis induced by cadmium. Carcinogenesis. vol 21. issue 7. 2000-08-17. PMID:10874022. |
in contrast, sb202190, an inhibitor of p38, decreased the cytotoxicity and apoptosis induced by high cd doses. |
2000-08-17 |
2023-08-12 |
human |
| S M Chuang, I C Wang, J L Yan. Roles of JNK, p38 and ERK mitogen-activated protein kinases in the growth inhibition and apoptosis induced by cadmium. Carcinogenesis. vol 21. issue 7. 2000-08-17. PMID:10874022. |
transfection of wild-type jnk2 or p38 enhanced apoptosis of cells exposed to low cd doses but did not affect those exposed to high cd doses. |
2000-08-17 |
2023-08-12 |
human |
| S M Chuang, I C Wang, J L Yan. Roles of JNK, p38 and ERK mitogen-activated protein kinases in the growth inhibition and apoptosis induced by cadmium. Carcinogenesis. vol 21. issue 7. 2000-08-17. PMID:10874022. |
together, the results of this study suggest that jnk and p38 cooperatively participate in apoptosis induced by cd and that the decreased erk signal induced by low cd doses contributes to growth inhibition or apoptosis. |
2000-08-17 |
2023-08-12 |
human |
| T Hieronymus, N Blank, M Gruenke, S Winkler, J P Haas, J R Kalden, H M Loren. CD 95-independent mechanisms of IL-2 deprivation-induced apoptosis in activated human lymphocytes. Cell death and differentiation. vol 7. issue 6. 2000-08-08. PMID:10822277. |
cd 95-independent mechanisms of il-2 deprivation-induced apoptosis in activated human lymphocytes. |
2000-08-08 |
2023-08-12 |
human |
| T Hieronymus, N Blank, M Gruenke, S Winkler, J P Haas, J R Kalden, H M Loren. CD 95-independent mechanisms of IL-2 deprivation-induced apoptosis in activated human lymphocytes. Cell death and differentiation. vol 7. issue 6. 2000-08-08. PMID:10822277. |
lymphoblasts from patients with cd 95 (fas/apo-1)-deficiency revealed that functional cd95 was not required to induce apoptosis after il-2 withdrawal. |
2000-08-08 |
2023-08-12 |
human |
| H Fujimaki, M Ishido, K Nohar. Induction of apoptosis in mouse thymocytes by cadmium. Toxicology letters. vol 115. issue 2. 2000-06-20. PMID:10802385. |
to investigate the induction of apoptosis and immunomodulation by environmental chemicals, we cultured mouse thymocytes with cd and/or dexamethasone (dex). |
2000-06-20 |
2023-08-12 |
mouse |
| H Fujimaki, M Ishido, K Nohar. Induction of apoptosis in mouse thymocytes by cadmium. Toxicology letters. vol 115. issue 2. 2000-06-20. PMID:10802385. |
exposure to 10 microm cd killed thymocytes by apoptosis rather than necrosis. |
2000-06-20 |
2023-08-12 |
mouse |
| H Fujimaki, M Ishido, K Nohar. Induction of apoptosis in mouse thymocytes by cadmium. Toxicology letters. vol 115. issue 2. 2000-06-20. PMID:10802385. |
however, no synergistic or additive effect was observed in the induction of apoptosis when dex was added to the cd. |
2000-06-20 |
2023-08-12 |
mouse |