| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| G Xu, G Zhou, T Jin, T Zhou, S Hammarström, A Bergh, G Nordber. Apoptosis and p53 gene expression in male reproductive tissues of cadmium exposed rats. Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine. vol 12. issue 2. 1999-07-30. PMID:10406082. |
reverse transcription (rt) pcr technique was used to investigate the mechanism of apoptosis induced by cd and the change of its related genes in testes and prostate of rats. |
1999-07-30 |
2023-08-12 |
rat |
| G Xu, G Zhou, T Jin, T Zhou, S Hammarström, A Bergh, G Nordber. Apoptosis and p53 gene expression in male reproductive tissues of cadmium exposed rats. Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine. vol 12. issue 2. 1999-07-30. PMID:10406082. |
the results indicated that cd can induce apoptosis in testes via p53-independent pathway. |
1999-07-30 |
2023-08-12 |
rat |
| K Ina, J Itoh, K Fukushima, K Kusugami, T Yamaguchi, K Kyokane, A Imada, D G Binion, A Musso, G A West, G M Dobrea, T S McCormick, E G Lapetina, A D Levine, C A Ottaway, C Fiocch. Resistance of Crohn's disease T cells to multiple apoptotic signals is associated with a Bcl-2/Bax mucosal imbalance. Journal of immunology (Baltimore, Md. : 1950). vol 163. issue 2. 1999-07-29. PMID:10395708. |
compared with control and uc, cd t cells grew remarkably more in response to il-2 and were significantly more resistant to il-2 deprivation-induced apoptosis. |
1999-07-29 |
2023-08-12 |
Not clear |
| K Ina, J Itoh, K Fukushima, K Kusugami, T Yamaguchi, K Kyokane, A Imada, D G Binion, A Musso, G A West, G M Dobrea, T S McCormick, E G Lapetina, A D Levine, C A Ottaway, C Fiocch. Resistance of Crohn's disease T cells to multiple apoptotic signals is associated with a Bcl-2/Bax mucosal imbalance. Journal of immunology (Baltimore, Md. : 1950). vol 163. issue 2. 1999-07-29. PMID:10395708. |
cd t cells were also more resistant to fas- and nitric oxide-mediated apoptosis, whereas tnf-alpha failed to induce cell death in all groups. |
1999-07-29 |
2023-08-12 |
Not clear |
| B A Hart, C H Lee, G S Shukla, A Shukla, M Osier, J D Eneman, J F Chi. Characterization of cadmium-induced apoptosis in rat lung epithelial cells: evidence for the participation of oxidant stress. Toxicology. vol 133. issue 1. 1999-07-29. PMID:10413193. |
cells, grown to near confluence, were exposed to 0-30 microm cdcl2 for 0-72 h. phase contrast microscopy and fluorescent nuclear staining showed that cd caused morphological alterations in lung epithelial cells that are characteristic of apoptosis. |
1999-07-29 |
2023-08-12 |
rat |
| B A Hart, C H Lee, G S Shukla, A Shukla, M Osier, J D Eneman, J F Chi. Characterization of cadmium-induced apoptosis in rat lung epithelial cells: evidence for the participation of oxidant stress. Toxicology. vol 133. issue 1. 1999-07-29. PMID:10413193. |
although the mechanisms by which cd initiates apoptosis in these cells are presently not known, reactive oxygen species are likely to play a role. |
1999-07-29 |
2023-08-12 |
rat |
| M Y Wu, P Y Wang, S H Han, S L Hsie. The cytoplasmic domain of the lymphotoxin-beta receptor mediates cell death in HeLa cells. The Journal of biological chemistry. vol 274. issue 17. 1999-05-20. PMID:10207006. |
we have observed that overexpression of either lt-betar or the cytoplasmic domain of lt-betar (lt-betar(cd)) also induces apoptosis, which may be attributed to the tendency of lt-betar(cd) to self-associate. |
1999-05-20 |
2023-08-12 |
Not clear |
| M Y Wu, P Y Wang, S H Han, S L Hsie. The cytoplasmic domain of the lymphotoxin-beta receptor mediates cell death in HeLa cells. The Journal of biological chemistry. vol 274. issue 17. 1999-05-20. PMID:10207006. |
the self-association domain of lt-betar(cd) was mapped to amino acids 324-377, a region of the protein that is also essential for lt-betar-induced apoptosis. |
1999-05-20 |
2023-08-12 |
Not clear |
| M Y Wu, P Y Wang, S H Han, S L Hsie. The cytoplasmic domain of the lymphotoxin-beta receptor mediates cell death in HeLa cells. The Journal of biological chemistry. vol 274. issue 17. 1999-05-20. PMID:10207006. |
furthermore, we have shown that lt-betar(cd)-induced apoptosis could be inhibited by a traf3 dominant negative mutant and by the caspase inhibitors z-vad-fmk, devd-fmk, and crma. |
1999-05-20 |
2023-08-12 |
Not clear |
| M Y Wu, P Y Wang, S H Han, S L Hsie. The cytoplasmic domain of the lymphotoxin-beta receptor mediates cell death in HeLa cells. The Journal of biological chemistry. vol 274. issue 17. 1999-05-20. PMID:10207006. |
the ligand-independent apoptosis induced by lt-betar(cd) will help us to further dissect lt-betar signaling pathway. |
1999-05-20 |
2023-08-12 |
Not clear |
| G W Wolkersdörfer, C Marx, T Lohmann, S Brauer, S Schröder, J Brown, N Mitsiades, G P Chrousos, S R Bornstei. The mercy of adrenocortical tumor cells on lymphocytes. Endocrine research. vol 24. issue 3-4. 1999-04-13. PMID:9888563. |
in a co-culture system of tumor cells and hla-matched leukocytes, cd 8-positive or cd 4-positive lymphocytes, we examined the immunologic escape and the ability to induce apoptosis in the immune cells. |
1999-04-13 |
2023-08-12 |
Not clear |
| G W Wolkersdörfer, C Marx, T Lohmann, S Brauer, S Schröder, J Brown, N Mitsiades, G P Chrousos, S R Bornstei. The mercy of adrenocortical tumor cells on lymphocytes. Endocrine research. vol 24. issue 3-4. 1999-04-13. PMID:9888563. |
the direct co-culture with either leukocytes, cd 8-positive or cd 4-positive lymphocytes reduced spontaneous apoptosis in immune cells from 49.9% to 13.0%, 8.6% and 15.3%, respectively, as determined by facs analysis of annexin v binding and ldh release in the medium. |
1999-04-13 |
2023-08-12 |
Not clear |
| M Ishido, C Tohyama, T Suzuk. Cadmium-bound metallothionein induces apoptosis in rat kidneys, but not in cultured kidney LLC-PK1 cells. Life sciences. vol 64. issue 9. 1999-03-29. PMID:10075112. |
administration of purified cd-mt (0.15 mg mt bound cd per kg body weight) to the rat induces dna fragmentation, a biochemical characteristic of apoptosis in the kidney at 16 h, which was detectable by ethidium bromide staining on an agarose gel. |
1999-03-29 |
2023-08-12 |
rat |
| M Ishido, C Tohyama, T Suzuk. Cadmium-bound metallothionein induces apoptosis in rat kidneys, but not in cultured kidney LLC-PK1 cells. Life sciences. vol 64. issue 9. 1999-03-29. PMID:10075112. |
to examine the effect of intracellular mt on cadmium-induced apoptosis in cultured cells, new cell lines were established, which constitutively produce mt, being termed as cd(r)-llc-pk1 cells since cd-mt exogenously added had much less permeability to the cultured cells. |
1999-03-29 |
2023-08-12 |
rat |
| M Ishido, C Tohyama, T Suzuk. Cadmium-bound metallothionein induces apoptosis in rat kidneys, but not in cultured kidney LLC-PK1 cells. Life sciences. vol 64. issue 9. 1999-03-29. PMID:10075112. |
in cd(r)-llc-pk1 cells, 10 microm cdcl2 failed to induce apoptosis, but 60 microm cdcl2 could exert the apoptotic response, indicating that intracellular mt which was induced by cdcl2 did not facilitate cdcl2-elicited apoptosis. |
1999-03-29 |
2023-08-12 |
rat |
| F Mentz, S Baudet, K Maloum, Z Azgui, O Sevin, M F Vinsobre, C Dujarric, K Brefort, M C Chretien, H Merle-Béra. Quantification of apoptosis by the Abbott CD4000 hematology analyzer. Hematology and cell therapy. vol 40. issue 5. 1999-01-26. PMID:9844812. |
after 36-hrs of culture the percentage of apoptotic cells of the sample was determined from the parameters of the cd 4000 described above and thereafter this was compared with reference methods for estimation of apoptosis. |
1999-01-26 |
2023-08-12 |
Not clear |
| C D Albright, S H Zeisel, R I Salgani. Choline deficiency induces apoptosis and decreases the number of eosinophilic preneoplastic foci in the liver of OXYS rats. Pathobiology : journal of immunopathology, molecular and cellular biology. vol 66. issue 2. 1998-09-08. PMID:9645630. |
choline deficiency (cd) was previously shown to trigger apoptosis in rat hepatocytes in culture and in vivo. |
1998-09-08 |
2023-08-12 |
rat |
| C D Albright, S H Zeisel, R I Salgani. Choline deficiency induces apoptosis and decreases the number of eosinophilic preneoplastic foci in the liver of OXYS rats. Pathobiology : journal of immunopathology, molecular and cellular biology. vol 66. issue 2. 1998-09-08. PMID:9645630. |
this study shows that the liver of oxys rats with an inherited overgeneration of free radicals retains sensitivity to cd, and that this p53-independent trigger of apoptosis can decrease the number of eosinophilic foci in the livers of these animals. |
1998-09-08 |
2023-08-12 |
rat |
| S N Rubtsova, R V Kondratov, P B Kopnin, P M Chumakov, B P Kopnin, J M Vasilie. Disruption of actin microfilaments by cytochalasin D leads to activation of p53. FEBS letters. vol 430. issue 3. 1998-08-13. PMID:9688570. |
cd also induces apoptosis in p53+/+, but not in p53-/- cells. |
1998-08-13 |
2023-08-12 |
Not clear |
| K Bulloch, B S McEwen, J Nordberg, A Diwa, S Bair. Selective regulation of T-cell development and function by calcitonin gene-related peptide in thymus and spleen. An example of differential regional regulation of immunity by the neuroendocrine system. Annals of the New York Academy of Sciences. vol 840. 1998-07-09. PMID:9629282. |
flow cytometric analysis of cgrp-treated cultures using antibodies to cluster determinates (cd) showed that the majority of thymocytes undergoing apoptosis induced by cgrp were of the cd4/cd8 double-positive type. |
1998-07-09 |
2023-08-12 |
Not clear |