| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hiroki Ishikawa, Motoko Ikeda, Kenichi Yanagimoto, Cristiano A Felipe Alves, Yasuhiro Katou, Barbara A Laviña-Caoili, Michihiro Kobayash. Induction of apoptosis in an insect cell line, IPLB-Ld652Y, infected with nucleopolyhedroviruses. The Journal of general virology. vol 84. issue Pt 3. 2003-03-27. PMID:12604823. |
northern blot and immunoblot analyses revealed that hycunpv inhibitor of apoptosis 3 (iap3), which has been shown to function in sf9 cells, was expressed in hycunpv-infected ld652y cells at a level higher than or comparable with that in hycunpv-infected spim cells, which produced a high titre of progeny virions without any apoptotic response. |
2003-03-27 |
2023-08-12 |
Not clear |
| Mi-Hyeon Jang, Min-Chul Shin, Hye-Sook Shin, Khae-Hawn Kim, Heung-Jae Park, Ee-Hwa Kim, Chang-Ju Ki. Alcohol induces apoptosis in TM3 mouse Leydig cells via bax-dependent caspase-3 activation. European journal of pharmacology. vol 449. issue 1-2. 2003-03-20. PMID:12163104. |
to investigate whether ethanol induces apoptosis in leydig cells, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (mtt) assay, terminal deoxynuclotidyl transferase-mediated dutp nick end-labeling (tunel) assay, 4,6-diamidino-2-phenylindole (dapi) staining, dna fragmentation assay, caspase-3 enzyme assay, reverse transcription-polymerase chain reaction (rt-pcr) and western blot analysis were performed on tm3 mouse leydig cells. |
2003-03-20 |
2023-08-12 |
mouse |
| Debra W Taylor, Michael W Lamé, Lynn S Nakayama, H J Segall, Dennis W Wilso. Effects of monocrotaline pyrrole and thrombin on pulmonary endothelial cell junction and matrix adhesion proteins. Toxicology. vol 184. issue 2-3. 2003-03-18. PMID:12499124. |
western blot analysis showed thrombin stimulated catalysis of zo-1 and fak while mctp pretreatment resulted in fak fragmentation similar to previous reports for apoptosis. |
2003-03-18 |
2023-08-12 |
Not clear |
| Marco Jara, Pedro Esponda, Rosa Carballad. Abdominal temperature induces region-specific p53-independent apoptosis in the cauda epididymidis of the mouse. Biology of reproduction. vol 67. issue 4. 2003-03-11. PMID:12297535. |
the complete molecular mechanism of apoptosis in this case remains unknown, but we have used the techniques of immunocytochemistry, western blot, and reverse transcription-polymerase chain reaction to determine the role of some molecules. |
2003-03-11 |
2023-08-12 |
mouse |
| Kirstan K Meldrum, Arthur L Burnett, Xianzhong Meng, Rosalia Misseri, Matthew B K Shaw, John P Gearhart, Daniel R Meldru. Liposomal delivery of heat shock protein 72 into renal tubular cells blocks nuclear factor-kappaB activation, tumor necrosis factor-alpha production, and subsequent ischemia-induced apoptosis. Circulation research. vol 92. issue 3. 2003-03-04. PMID:12595341. |
cells were subjected to simulated ischemia 24 hours after liposomal hsp72 transfer or thermal stress, and the effect of hsp72 on nuclear factor-kappab (nf-kappab) activation (electrophoretic mobility shift assay and immunohistochemistry), ikappabalpha production (western blot), postischemic tumor necrosis factor-alpha (tnf-alpha) production (rt-pcr), and apoptosis (tunel assay) were determined. |
2003-03-04 |
2023-08-12 |
Not clear |
| K Ohnishi, I Ota, A Takahashi, K Yane, H Matsumoto, T Ohnish. Transfection of mutant p53 gene depresses X-ray- or CDDP-induced apoptosis in a human squamous cell carcinoma of the head and neck. Apoptosis : an international journal on programmed cell death. vol 7. issue 4. 2003-02-12. PMID:12101396. |
the activation of caspase-3 was estimated as an indicator of apoptosis by the detection of fragmentation of caspase-3 or poly (adp ribose) polymerase (parp) with western blot. |
2003-02-12 |
2023-08-12 |
human |
| John Gordon, Ching-Huang Wu, Mojgan Rastegar, Ahmad R Saf. Beta2-microglobulin induces caspase-dependent apoptosis in the CCRF-HSB-2 human leukemia cell line independently of the caspase-3, -8 and -9 pathways but through increased reactive oxygen species. International journal of cancer. vol 103. issue 3. 2003-01-21. PMID:12471614. |
however, z-vad-fmk treatment significantly blocked beta(2)m-induced apoptosis, while western blot analysis revealed that caspases-1, -2, -3, -6, -7, -8 and -9 are not activated during beta(2)m-induced apoptosis in these cells. |
2003-01-21 |
2023-08-12 |
human |
| Sunghoon Kim, Junghee Kang, Wanqin Hu, B Mark Evers, Dai H Chun. Geldanamycin decreases Raf-1 and Akt levels and induces apoptosis in neuroblastomas. International journal of cancer. vol 103. issue 3. 2003-01-21. PMID:12471618. |
apoptosis was assessed with dna fragmentation elisa, tunel-flow cytometric assay, western blot and caspase activities. |
2003-01-21 |
2023-08-12 |
human |
| H Ying, S Subrat. [S-phase arrest associated apoptosis leads to diversities of drug resistance and mutation rate in human breast cancer cells]. Hua xi yi ke da xue xue bao = Journal of West China University of Medical Sciences = Huaxi yike daxue xuebao. vol 30. issue 2. 2003-01-14. PMID:12212041. |
further, by means of cell growth rate test, flow cytometry, measurement of dna fragmentation and western blot, the relationship between drug resistance and mutation rate and cell cycle control and apoptosis was explored. |
2003-01-14 |
2023-08-12 |
human |
| Koichiro Yoshida, Kazuyoshi Kuwano, Naoki Hagimoto, Kentaro Watanabe, Tokuji Matsuba, Masaki Fujita, Ichiro Inoshima, Nobuyuki Har. MAP kinase activation and apoptosis in lung tissues from patients with idiopathic pulmonary fibrosis. The Journal of pathology. vol 198. issue 3. 2003-01-07. PMID:12375272. |
the expression of the active erk, jnk, and p38 mapk was examined using western blot analysis and immunohistochemistry and apoptosis was also examined by the tunel method, in lung tissues from ten patients with ipf obtained by thoracoscopic biopsy and in eight normal lung parenchyma specimens obtained by lobectomy for lung cancer. |
2003-01-07 |
2023-08-12 |
Not clear |
| Omer Kucuk, Fazlul H Sarkar, Zora Djuric, Wael Sakr, Michael N Pollak, Fred Khachik, Mousumi Banerjee, John S Bertram, David P Woo. Effects of lycopene supplementation in patients with localized prostate cancer. Experimental biology and medicine (Maywood, N.J.). vol 227. issue 10. 2002-12-19. PMID:12424329. |
biomarkers of cell proliferation and apoptosis were assessed by western blot analysis in benign and cancerous prostate tissues. |
2002-12-19 |
2023-08-12 |
human |
| Heinz Baisc. Elevated Ki-67 expression is correlated with TNFalpha- and IFNgamma-induced apoptosis in tumour cells. Cell proliferation. vol 35. issue 6. 2002-12-13. PMID:12427252. |
the ki-67 level was determined by flow cytometry and apoptosis was measured by various methods including parp degradation (western blot) in detached and floating cells. |
2002-12-13 |
2023-08-12 |
human |
| Basil F El-Rayes, Robert Grignon, Naveed Aslam, Olivia Aranha, Fazlul H Sarka. Ciprofloxacin inhibits cell growth and synergises the effect of etoposide in hormone resistant prostate cancer cells. International journal of oncology. vol 21. issue 1. 2002-12-02. PMID:12063570. |
western blot analysis of the protein extracts from these cells showed down-regulation of bcl-2, altering the ratio of bax:bcl-2 favoring apoptosis. |
2002-12-02 |
2023-08-12 |
human |
| Harold J Sheedlo, Bhooma Srinivasan, Anne Marie Brun-Zinkernagel, Criselda H Roque, Wendi Lambert, Robert J Wordinger, Rouel S Roqu. Expression of p75(NTR) in photoreceptor cells of dystrophic rat retinas. Brain research. Molecular brain research. vol 103. issue 1-2. 2002-11-06. PMID:12106693. |
in this study, the expression of p75(ntr), the low-affinity neurotrophin receptor incriminated in the apoptosis of developing neurons, was investigated at various stages of retinal degeneration in dystrophic rats using immunohistochemistry, in situ reverse transcription polymerase chain reaction (rt-pcr), western blot, and relative rt-pcr. |
2002-11-06 |
2023-08-12 |
rat |
| Joon Song, Thomas Rutherford, Frederick Naftolin, Santiago Brown, Gil Mo. Hormonal regulation of apoptosis and the Fas and Fas ligand system in human endometrial cells. Molecular human reproduction. vol 8. issue 5. 2002-10-30. PMID:11994542. |
apoptosis was determined by 3-[4,5-dimethylthiazol-2-yl]-2,5-dephenyl tetrazolium bromide (mtt) assay and propidium iodide staining, while fas and fasl expression were evaluated by western blot analysis. |
2002-10-30 |
2023-08-12 |
human |
| Hiroaki Sasaki, Shoji Fukuda, Hajime Otani, Li Zhu, Genbu Yamaura, Richard M Engelman, Dipak K Das, Nilanjana Mauli. Hypoxic preconditioning triggers myocardial angiogenesis: a novel approach to enhance contractile functional reserve in rat with myocardial infarction. Journal of molecular and cellular cardiology. vol 34. issue 3. 2002-10-21. PMID:11945025. |
western blot analysis was performed to measure vegf expression and tunel staining with endothelial cell-specific antibody, anti-vwf, was used to examine endothelial apoptosis. |
2002-10-21 |
2023-08-12 |
rat |
| Wilfried Kugler, Bernhard Erdlenbruch, Anja Jünemann, Dagmar Heinemann, Hansjörg Eibl, Max Lakome. Erucylphosphocholine-induced apoptosis in glioma cells: involvement of death receptor signalling and caspase activation. Journal of neurochemistry. vol 82. issue 5. 2002-10-18. PMID:12358763. |
western blot analysis indicated that erpc-triggered apoptosis resulted in a time-dependent processing of caspases-3, -7, -8 and -9 into their respective active subunits. |
2002-10-18 |
2023-08-12 |
Not clear |
| Wan-Qian Zhao, Zakia Williams, Kennie R Shepherd, Jayne S Reuben, Eun-Sook Lee, Selina Darling-Reed, Nazarius Lamango, Karam F A Soliman, Clivel G Charlto. S-adenosyl-methionine-induced apoptosis in PC12 cells. Journal of neuroscience research. vol 69. issue 4. 2002-10-16. PMID:12210845. |
apoptosis of pc12 cells was also assessed by parp cleavage detection, western blot analysis of bax and bcl-2 proteins, and dna laddering on agarose gel electrophoresis. |
2002-10-16 |
2023-08-12 |
rat |
| Jun Araya, Muneharu Maruyama, Akira Inoue, Tadashi Fujita, Junko Kawahara, Kazuhiko Sassa, Ryuji Hayashi, Yukio Kawagishi, Naohiro Yamashita, Eiji Sugiyama, Masashi Kobayash. Inhibition of proteasome activity is involved in cobalt-induced apoptosis of human alveolar macrophages. American journal of physiology. Lung cellular and molecular physiology. vol 283. issue 4. 2002-10-10. PMID:12225962. |
to evaluate this, we exposed u-937 cells and human alveolar macrophages (ams) to cobalt chloride (cocl(2)) and examined their apoptosis by dna fragmentation assay, 4',6-diamidino-2'-phenylindol dihydrochloride staining, and western blot analysis. |
2002-10-10 |
2023-08-12 |
human |
| X Luan, T G H Diekwisc. CP27 affects viability, proliferation, attachment and gene expression in embryonic fibroblasts. Cell proliferation. vol 35. issue 4. 2002-09-13. PMID:12153613. |
following cell culture, cell viability, apoptosis, cell proliferation, cell shape, cellular attachment and fibronectin matrix production were assayed using mtt colourimetric assay, brdu staining, morphometry, immunostaining and western blot analysis. |
2002-09-13 |
2023-08-12 |
rabbit |