| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Peng Wei, Xuan Jin, Shi-Xin Tao, Chun-Sheng Han, Yi-Xun Li. Fas, FasL, Bcl-2, and Bax in the endometrium of rhesus monkey during the menstrual cycle. Molecular reproduction and development. vol 70. issue 4. 2005-07-15. PMID:15685630. |
to study possible role and regulation of apoptosis occurred in primate endometrium, the expression of apoptosis-related molecules, fas, fasl, b cell lymphoma/leukaemia-2 (bcl-2), and bax were analyzed in relation to occurrence of apoptosis and proliferation in the cycling endometrium of the rhesus monkey using immunohistochemistry and western blot. |
2005-07-15 |
2023-08-12 |
monkey |
| Joanna Zarzyńska, Małgorzata Gajewska, Tomasz Moty. Effects of hormones and growth factors on TGF-beta1 expression in bovine mammary epithelial cells. The Journal of dairy research. vol 72. issue 1. 2005-07-06. PMID:15747730. |
rt-pcr, western blot and laser scanning cytometry (lsc) were used for analysis of tgf-beta1 transcript and protein level as well as apoptosis and cell cycle in examined mec. |
2005-07-06 |
2023-08-12 |
cattle |
| H Lee, H Park, Y J Kim, H J Kim, Y M Ahn, B Park, J H Park, B Eun Le. Expression of lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) in human preeclamptic placenta: possible implications in the process of trophoblast apoptosis. Placenta. vol 26. issue 2-3. 2005-07-05. PMID:15708124. |
in this study, we examined the expression of lox-1 in the human placentas of normal pregnancies and in preeclampsia using immunohistochemistry and western blot analysis, and proposed that lox-1 has a role in trophoblast apoptosis. |
2005-07-05 |
2023-08-12 |
human |
| Esther Llagostera, Vanessa Soto-Cerrato, Ricky Joshi, Beatriz Montaner, Pepita Gimenez-Bonafé, Ricardo Pérez-Tomá. High cytotoxic sensitivity of the human small cell lung doxorubicin-resistant carcinoma (GLC4/ADR) cell line to prodigiosin through apoptosis activation. Anti-cancer drugs. vol 16. issue 4. 2005-07-05. PMID:15746575. |
we observed through western blot that pg mediated cytochrome c release, caspase cascade activation and parp cleavage, thereby leading to apoptosis in a dose-response manner. |
2005-07-05 |
2023-08-12 |
human |
| Irina Panteleeva, Caroline Rouaux, Yves Larmet, Stéphanie Boutillier, Jean-Philippe Loeffler, Anne-Laurence Boutillie. HDAC-3 participates in the repression of e2f-dependent gene transcription in primary differentiated neurons. Annals of the New York Academy of Sciences. vol 1030. 2005-06-16. PMID:15659849. |
indeed, western blot analysis showed a time-dependent degradation of the rb/e2f binding protein hdac-3 during apoptosis, a degradation that is caspase-dependent. |
2005-06-16 |
2023-08-12 |
Not clear |
| Zhihong Hu, Mohammed M Sayee. Activation of PI3-kinase/PKB contributes to delay in neutrophil apoptosis after thermal injury. American journal of physiology. Cell physiology. vol 288. issue 5. 2005-06-09. PMID:15625305. |
expression levels of inhibitory apoptosis proteins (iaps), including cellular iap1 (ciap1), ciap2, x-linked iap (xiap), and survivin, and bcl-2 family members such as bcl-xl and bad, were determined by western blot analysis and/or rt-pcr, real-time pcr. |
2005-06-09 |
2023-08-12 |
rat |
| Y Hosaka, H Teraoka, E Yamamoto, H Ueda, K Takehan. Mechanism of cell death in inflamed superficial digital flexor tendon in the horse. Journal of comparative pathology. vol 132. issue 1. 2005-05-26. PMID:15629479. |
to detect apoptosis and to identify apoptotic cells, the samples were subjected to immunohistochemical labelling and western blot analysis. |
2005-05-26 |
2023-08-12 |
Not clear |
| Y Hosaka, H Teraoka, E Yamamoto, H Ueda, K Takehan. Mechanism of cell death in inflamed superficial digital flexor tendon in the horse. Journal of comparative pathology. vol 132. issue 1. 2005-05-26. PMID:15629479. |
excessive apoptosis was confirmed by the results of western blot analysis, which showed a significant increase in activated caspase-3 protein in the inflamed sdfts, suggesting that apoptosis occurred in the tendinocytes via a caspase-3-dependent pathway. |
2005-05-26 |
2023-08-12 |
Not clear |
| Jeong-Hyang Park, Lan Liu, In-Hee Kim, Jong-Hyun Kim, Kyung-Ran You, Dae-Ghon Ki. Identification of the genes involved in enhanced fenretinide-induced apoptosis by parthenolide in human hepatoma cells. Cancer research. vol 65. issue 7. 2005-05-26. PMID:15805281. |
the genes involved in the enhanced fenretinide-induced apoptosis by parthenolide were identified using the differential display-pcr method and subsequent northern blot or semiquantitative reverse transcriptase pcr analysis. |
2005-05-26 |
2023-08-12 |
human |
| Stephen Hsu, Kajuana Farrey, John Wataha, Jill Lewis, James Borke, Baldev Singh, Haiyan Qin, Carol Lapp, David Lapp, Tuan Nguyen, George Schuste. Role of p21WAF1 in green tea polyphenol-induced growth arrest and apoptosis of oral carcinoma cells. Anticancer research. vol 25. issue 1A. 2005-05-16. PMID:15816520. |
the current study determined the impact of sirna-suppressed p21waf1 and its response to egcg on cell growth, dna synthesis and apoptosis by rt-pcr, western blot, brdu incorporation, mtt and caspase 3 activity assays. |
2005-05-16 |
2023-08-12 |
Not clear |
| Je Seon Song, Yong Duk Park, Jin Won Hyun, Jeong Hee Ki. Induction of apoptosis by sodium fluorosilicate treatment in human osteogenic sarcoma (HOS) cells. Anticancer research. vol 25. issue 1A. 2005-05-16. PMID:15816563. |
the molecular mechanism of apoptosis induction in hos was investigated by western blot analysis. |
2005-05-16 |
2023-08-12 |
human |
| J Y W Chan, J Y N Cheung, S C W Luk, Y J Wu, S F Pang, K P Fun. Anti-cancer and pro-apoptotic effects of an herbal medicine and Saccharomyces cerevisiae product (CKBM) on human hepatocellular carcinoma HepG2 cells in vitro and in vivo. Immunopharmacology and immunotoxicology. vol 26. issue 4. 2005-05-11. PMID:15658608. |
the results of morphological changes, detection of dna fragmentation, flow cytometric analysis and western blot analysis indicated that this anti-tumor effect of ckbm was mediated via the process of apoptosis. |
2005-05-11 |
2023-08-12 |
mouse |
| Edward A Acheampong, Zahida Parveen, Lois W Muthoga, Mehrnush Kalayeh, Muhammad Mukhtar, Roger J Pomerant. Human Immunodeficiency virus type 1 Nef potently induces apoptosis in primary human brain microvascular endothelial cells via the activation of caspases. Journal of virology. vol 79. issue 7. 2005-04-26. PMID:15767427. |
western blot analyses revealed that the various caspases involved with nef-induced apoptosis are processed into cleavage products, which occur only during programmed cell death. |
2005-04-26 |
2023-08-12 |
human |
| Matthias Kappler, Helge Taubert, Frank Bartel, Karen Blümke, Matti Panian, Hannelore Schmidt, Jürgen Dunst, Matthias Bach. Radiosensitization, after a combined treatment of survivin siRNA and irradiation, is correlated with the activation of caspases 3 and 7 in a wt-p53 sarcoma cell line, but not in a mt-p53 sarcoma cell line. Oncology reports. vol 13. issue 1. 2005-04-25. PMID:15583820. |
the effects of combined treatment of sirna treatment and irradiation were investigated by clonogenic survival assay, measurement of activity of caspases 3 and 7, western blot hybridization for survivin and p53, and morphological analysis of apoptosis. |
2005-04-25 |
2023-08-12 |
Not clear |
| Hongyan Qu, Ronald L Madl, Dolores J Takemoto, Richard C Baybutt, Weiqun Wan. Lignans are involved in the antitumor activity of wheat bran in colon cancer SW480 cells. The Journal of nutrition. vol 135. issue 3. 2005-04-14. PMID:15735100. |
western blot analysis for cyclin a, a required protein for s/g2 transition, showed that the cyclin a protein levels decreased after treatment with enterodiol or the combination of enterolactone and enterodiol at 40 micromol/l for 72 h. apoptosis analysis by the terminal deoxynucleotidyl transferase-mediated dutp nick end labeling assay showed an increased percentage of apoptotic cells in the floating cells after enterodiol alone or combined treatments. |
2005-04-14 |
2023-08-12 |
mouse |
| S Schweyer, A Soruri, A Heintze, H J Radzun, A Fayyaz. The role of reactive oxygen species in cisplatin-induced apoptosis in human malignant testicular germ cell lines. International journal of oncology. vol 25. issue 6. 2005-04-05. PMID:15547704. |
applying western blot and phosphorylated kinase-specific elisa analyses, flow cytometry, blocking experiments, and morphological methods we sought here to define the mapk pathway(s) involved in the cddp-induced apoptosis in the human tgct cell line nccit. |
2005-04-05 |
2023-08-12 |
human |
| J J Liu, R W Huang, D J Lin, J Peng, X Y Wu, X L Pan, M Q Li, Q Li. Anti-proliferative effects of oridonin on SPC-A-1 cells and its mechanism of action. The Journal of international medical research. vol 32. issue 6. 2005-03-24. PMID:15587755. |
marked morphological changes indicative of apoptosis were observed, especially in cells treated with oridonin for 48 - 60 h. western blot analysis revealed downregulation of bcl-2 and upregulation of bax proteins following treatment with oridonin for 48 h. we conclude that oridonin demonstrated anti-proliferative and apoptosis-inducing effects on spc-a-1 cells in vitro, and that changes in bcl-2 and bax protein levels may play an important role in its mechanism of action. |
2005-03-24 |
2023-08-12 |
Not clear |
| Gloria A Gronowicz, Mary-Beth McCarthy, Hai Zhang, Wenjian Zhan. Insulin-like growth factor II induces apoptosis in osteoblasts. Bone. vol 35. issue 3. 2005-03-22. PMID:15336597. |
western blot analysis of bcl-2 and bax levels demonstrated a transient decrease in the bcl-2/bax ratio at 24 h with no decrease in the ratio at 48 or 72 h. thus, igf-ii appears to promote osteoblast apoptosis, and overexpression of bcl-2 is able to block igf-ii-induced apoptosis. |
2005-03-22 |
2023-08-12 |
mouse |
| Dominique S Tews, Wera Behrhof, Susanne Schindle. Expression patterns of initiator and effector caspases in denervated human skeletal muscle. Muscle & nerve. vol 31. issue 2. 2005-03-10. PMID:15625686. |
in 17 patients with neurogenic muscular atrophy, we studied the expression of the apoptosis mediators apaf-1/caspase-9 and degrading caspases-2, -3, and -7 by immunohistochemical and western blot analyses. |
2005-03-10 |
2023-08-12 |
human |
| O L Huk, D J Zukor, W Ralston, A Lisbona, A Peti. Apoptosis in interface membranes of aseptically loose total hip arthroplasty. Journal of materials science. Materials in medicine. vol 12. issue 7. 2005-03-08. PMID:15348259. |
finally, using western blot analysis, we observed the appearance of the 89 kda parp fragment associated with apoptosis in 92% of specimens (30/33). |
2005-03-08 |
2023-08-12 |
Not clear |