| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hong-Mei Yang, Gang Liu, Zhao-Yan Nie, Dong-Song Nie, Yun Deng, Guang-Xiu L. Molecular cloning of a novel rat gene Tsarg1, a member of the DnaJ/HSP40 protein family. DNA sequence : the journal of DNA sequencing and mapping. vol 16. issue 3. 2006-07-03. PMID:16147871. |
the results of rt-pcr and northern blot analysis showed that tsarg1 was specifically expressed in rat testis, which probably inhibits rat testis spermatogenic cell apoptosis. |
2006-07-03 |
2023-08-12 |
mouse |
| Xinbo Zhang, Frederick L Kiechl. Fatty acid synthase and its mRNA concentrations are decreased at different times following Hoechst 33342-induced apoptosis in BC3H-1 myocytes. Annals of clinical and laboratory science. vol 36. issue 2. 2006-06-26. PMID:16682516. |
hoechst 33342-induced apoptosis in bc3h-1 myocytes was used as a model to explore intracellular changes in fas protein (western blot) and fas mrna (rt-pcr). |
2006-06-26 |
2023-08-12 |
Not clear |
| Fengqin Dong, Wei Guo, Lidong Zhang, Shuhong Wu, Fuminori Teraishi, John J Davis, Bingliang Fan. Downregulation of XIAP and induction of apoptosis by the synthetic cyclin-dependent kinase inhibitor GW8510 in non-small cell lung cancer cells. Cancer biology & therapy. vol 5. issue 2. 2006-06-22. PMID:16322690. |
western blot analysis showed that gw8510 downregulated the expression of x-linked inhibitor of apoptosis (xiap) but had no detectable effect on the expression of bax, bak, or bcl2. |
2006-06-22 |
2023-08-12 |
human |
| E Homsi, P Janino, J B L de Fari. Role of caspases on cell death, inflammation, and cell cycle in glycerol-induced acute renal failure. Kidney international. vol 69. issue 8. 2006-06-22. PMID:16557226. |
renal function, renal histology (he), transferase-mediated deoxynucleotidyl transferase deoxyuridine triphosphate nick end labeling staining for apoptosis, leukocytes infiltration (immunohistochemistry), renal expression of il-1beta and il-18 (immunohistochemistry and western blot), tubular regeneration (5-bromo-2'-deoxyuridine (brdu) incorporation), and p27(kip) expression (western blot) were evaluated at appropriate times. |
2006-06-22 |
2023-08-12 |
rat |
| Nauman Ahmad, Yigang Wang, Khawaja Husnain Haider, Boyu Wang, Zeeshan Pasha, Ozge Uzun, Muhammad Ashra. Cardiac protection by mitoKATP channels is dependent on Akt translocation from cytosol to mitochondria during late preconditioning. American journal of physiology. Heart and circulatory physiology. vol 290. issue 6. 2006-06-22. PMID:16687609. |
moreover, bms and de accelerated akt phosphorylation in cardiac tissue as determined by western blot analysis and also significantly reduced apoptosis compared with ischemic control. |
2006-06-22 |
2023-08-12 |
mouse |
| Yoshiko Misonou, Michio Asahi, Shunichi Yokoe, Eiji Miyoshi, Naoyuki Taniguch. Acrolein produces nitric oxide through the elevation of intracellular calcium levels to induce apoptosis in human umbilical vein endothelial cells: implications for smoke angiopathy. Nitric oxide : biology and chemistry. vol 14. issue 2. 2006-06-16. PMID:16275026. |
nuclear staining and a western blot analysis using an anti-cleaved caspase 3 antibody revealed that the reduced viability of huvec by acrolein was due to apoptosis, which was reversed after pretreatment with 0.1mm carboxy-ptio or 1mm l-name. |
2006-06-16 |
2023-08-12 |
human |
| J Wu, T Liu, J Xie, F Xin, L Gu. Mitochondria and calpains mediate caspase-dependent apoptosis induced by doxycycline in HeLa cells. Cellular and molecular life sciences : CMLS. vol 63. issue 7-8. 2006-06-16. PMID:16596338. |
western blot data demonstrated that cytochrome c (cyt c), smac (the second mitochondria-derived activator of caspase), calpain i, caspase-9, -3 and -8 were involved in the apoptotic process, while the pan caspase inhibitor zvad-fmk almost completely inhibited dc-induced apoptosis. |
2006-06-16 |
2023-08-12 |
Not clear |
| Jian-Hua Zhang, Ming-Xi Wan, Bo-Rong Pan, Bing Y. Cytotoxicity of HSVtk and hrTNF-alpha fusion genes with IRES in treatment of gastric cancer. Cancer letters. vol 235. issue 2. 2006-06-15. PMID:16752439. |
the pl(tk-tnf-alpha)sn harboring hsvtk and tnf-alpha genes in sequence was constructed with a bicistronic unit including the internal ribosomal entry site, the recombinant retroviruses were transferred into sgc7901 cells by lipofectamine, and pegfp and western blot analysis were used to detect the expression of fusion genes in transfected sgc7901 cells, and then apoptosis of the transfected cells were detected by using the tdt-mediated dutp nick end labeling, flow cytometric analysis and transmission electron microscopy. |
2006-06-15 |
2023-08-12 |
mouse |
| Yueh-Hsin Ping, Hsin-Chen Lee, Jen-Yi Lee, Pin-Ho Wu, Li-Kang Ho, Chin-Wen Chi, Ming-Fong Lu, Jane-Jen Wan. Anticancer effects of low-dose 10-hydroxycamptothecin in human colon cancer. Oncology reports. vol 15. issue 5. 2006-06-13. PMID:16596197. |
flow cytometry analysis and western blot and apoptosis assays demonstrated that low-dose 10-hcpt arrested colo 205 cells in the g2 phase of the cell cycle and triggered apoptosis through a caspase-3-dependent pathway. |
2006-06-13 |
2023-08-12 |
mouse |
| Ho Lam Tang, Anh-Huy Phan Le, Hong Lok Lun. The increase in mitochondrial association with actin precedes Bax translocation in apoptosis. The Biochemical journal. vol 396. issue 1. 2006-05-31. PMID:16536728. |
using cell fractionation and western blot analysis, we found that mitochondrial accumulation of beta-actin occurred before the mitochondrial insertion of bax and release of cytochrome c in apoptosis. |
2006-05-31 |
2023-08-12 |
Not clear |
| Jing-Hsien Chen, Fen-Pi Chou, Hui-Hsuan Lin, Chau-Jong Wan. Gaseous nitrogen oxide repressed benzo[a]pyrene-induced human lung fibroblast cell apoptosis via inhibiting JNK1 signals. Archives of toxicology. vol 79. issue 12. 2006-05-22. PMID:16041517. |
western blot data revealed that no gas increased the expressions of anti-apoptosis proteins (bcl-2 and mcl-1) and decreased the expression of apoptosis proteins (bax, t-bid, cytochrome c, fasl, and caspases) after b[a]p treatment. |
2006-05-22 |
2023-08-12 |
human |
| Juliana J Oh, Ali Razfar, Idolina Delgado, Rebecca A Reed, Anna Malkina, Baher Boctor, Dennis J Slamo. 3p21.3 tumor suppressor gene H37/Luca15/RBM5 inhibits growth of human lung cancer cells through cell cycle arrest and apoptosis. Cancer research. vol 66. issue 7. 2006-05-22. PMID:16585163. |
to further define h37's function in cell cycle/apoptotic pathways, we investigated differential expression profiles of various cell cycle and apoptosis regulatory proteins using western blot analysis. |
2006-05-22 |
2023-08-12 |
human |
| Stephan Brand, Florian Beigel, Torsten Olszak, Kathrin Zitzmann, Sören T Eichhorst, Jan-Michel Otte, Helmut Diepolder, Andreas Marquardt, Wolfgang Jagla, Andreas Popp, Stéphane Leclair, Karin Herrmann, Julia Seiderer, Thomas Ochsenkühn, Burkhard Göke, Christoph J Auernhammer, Julia Dambache. IL-22 is increased in active Crohn's disease and promotes proinflammatory gene expression and intestinal epithelial cell migration. American journal of physiology. Gastrointestinal and liver physiology. vol 290. issue 4. 2006-05-10. PMID:16537974. |
signal transduction was analyzed by western blot experiments, cell proliferation by 3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2h-tetrazolium assay and fas-induced apoptosis by flow cytometry. |
2006-05-10 |
2023-08-12 |
human |
| Z Wang, Y P Rong, M H Malone, M C Davis, F Zhong, C W Distelhors. Thioredoxin-interacting protein (txnip) is a glucocorticoid-regulated primary response gene involved in mediating glucocorticoid-induced apoptosis. Oncogene. vol 25. issue 13. 2006-05-04. PMID:16301999. |
this result was confirmed by northern blot analysis in multiple models of dexamethasone-induced apoptosis. |
2006-05-04 |
2023-08-12 |
mouse |
| Yujie Sun, Ting Wang, Yongqian Su, Yongmei Yin, Shan Xu, Changyan Ma, Xiao Ha. The behavior of SATB1, a MAR-binding protein, in response to apoptosis stimulation. Cell biology international. vol 30. issue 3. 2006-04-21. PMID:16377216. |
to further understand the functional role of mar-binding proteins during apoptosis we investigated the relationship of the behavior of satb1 and the collapse of nuclear architecture in jurkat cells with immunostaining and western blot analysis. |
2006-04-21 |
2023-08-12 |
Not clear |
| Peter E Mouser, Elizabeth Head, Kwang-Ho Ha, Troy T Roh. Caspase-mediated cleavage of glial fibrillary acidic protein within degenerating astrocytes of the Alzheimer's disease brain. The American journal of pathology. vol 168. issue 3. 2006-04-19. PMID:16507909. |
in vitro characterization of this antibody using both a cell-free system and a cell model system of apoptosis demonstrated that the antibody (termed gfap caspase-cleavage product antibody or gfap-ccp ab) immunolabeled the predicted caspase-cleavage fragment, but not full-length gfap, by western blot analysis. |
2006-04-19 |
2023-08-12 |
Not clear |
| Paola Bianciardi, Monica Fantacci, Anna Caretti, Raffaella Ronchi, Giuseppina Milano, Sandrine Morel, Ludwig von Segesser, Antonio Corno, Michele Samaj. Chronic in vivo hypoxia in various organs: hypoxia-inducible factor-1alpha and apoptosis. Biochemical and biophysical research communications. vol 342. issue 3. 2006-04-19. PMID:16596722. |
we measured hif-1alpha (immunohistochemistry peroxidase and western blot) and apoptosis (tunel) in heart, liver, kidney, gastrocnemius, and brain of rats exposed to chronic normobaric hypoxia (10% o2) or normoxia (21% o2) for 2 weeks. |
2006-04-19 |
2023-08-12 |
rat |
| H-Y Yang, S-F Leu, Y-K Wang, C-S Wu, B-M Huan. Cordyceps sinensis mycelium induces MA-10 mouse Leydig tumor cell apoptosis by activating the caspase-8 pathway and suppressing the NF-kappaB pathway. Archives of andrology. vol 52. issue 2. 2006-04-18. PMID:16443586. |
western blot analysis showed that 3 hours of cs treatment caused an increase in caspase-3 and -8 expressions only, which provided further evidence for the involvement of caspase-3 and -8 in cs-induced ma-10-cell apoptosis. |
2006-04-18 |
2023-08-12 |
mouse |
| Orla M Casey, Dermot G Morris, Richard Powell, Joseph M Sreenan, Richard Fitzpatric. Analysis of gene expression in non-regressed and regressed bovine corpus luteum tissue using a customized ovarian cDNA array. Theriogenology. vol 64. issue 9. 2006-03-23. PMID:15953631. |
results for five of the differentially expressed genes including matrix gla protein and collagen alpha1(i) (extracellular matrix), glutathione-s-transferase alpha i (oxygen metabolism), clusterin (apoptosis) and scavenger receptor bi (steroid biosynthesis) were confirmed by northern blot analysis and found to be significantly different (p<0.01) between non-regressed and regressed cl tissue. |
2006-03-23 |
2023-08-12 |
cattle |
| Ki M Kim, Jae J Song, Jee Young An, Yong Tae Kwon, Yong J Le. Pretreatment of acetylsalicylic acid promotes tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by down-regulating BCL-2 gene expression. The Journal of biological chemistry. vol 280. issue 49. 2006-03-06. PMID:16199534. |
western blot analysis showed that pretreatment of asa followed by trail treatment activated caspases (8, 9, and 3) and cleaved poly(adp-ribose) polymerase, the hallmark feature of apoptosis. |
2006-03-06 |
2023-08-12 |
human |