| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yanwei Cao, Sreedhar Sagi, Axel Häcker, Annette Steidler, Peter Alken, Thomas Knol. Impact of hypoxia and hypercapnia on calcium oxalate toxicity in renal epithelial and interstitial cells. Urological research. vol 34. issue 4. 2006-11-01. PMID:16633808. |
dapi staining and western blot were used to evaluate the induction of apoptosis. |
2006-11-01 |
2023-08-12 |
human |
| Chi Keung Lau, Zhen Fan Yang, Chi Tat Lam, Ka Ho Tam, Ronnie Tung Ping Poon, Sheung Tat Fa. Suppression of hypoxia inducible factor-1alpha (HIF-1alpha) by YC-1 is dependent on murine double minute 2 (Mdm2). Biochemical and biophysical research communications. vol 348. issue 4. 2006-10-19. PMID:16919599. |
the phenotypic and molecular changes of cells were determined by cell proliferation assay, apoptosis assay, luciferase promoter assay, and western blot analysis. |
2006-10-19 |
2023-08-12 |
Not clear |
| Chi-Hsiao Yeh, Tzu-Ping Chen, Chieh-Hung Lee, Yi-Chen Wu, Yu-Min Lin, Pyng Jing Li. Cardiomyocytic apoptosis following global cardiac ischemia and reperfusion can be attenuated by peroxisome proliferator-activated receptor alpha but not gamma activators. Shock (Augusta, Ga.). vol 26. issue 3. 2006-10-10. PMID:16912651. |
the myocardium of the reperfused hearts and control hearts were harvested and studied in vitro for evidence of apoptosis using terminal deoxynucleotidyl transferase-mediated dutp-biotin nick-end labeling method and western blot analyses of cytochrome c and apoptosis-inducing factor. |
2006-10-10 |
2023-08-12 |
Not clear |
| Yan-Qiu Liu, Zhen-Qiang Mu, Song You, Shin-ichi Tashiro, Satoshi Onodera, Takashi Ikejim. Fas/FasL signaling allows extracelluar-signal regulated kinase to regulate cytochrome c release in oridonin-induced apoptotic U937 cells. Biological & pharmaceutical bulletin. vol 29. issue 9. 2006-10-05. PMID:16946501. |
western blot analysis showed the up-regulated expression of fas, fasl, and fadd, and down-regulated expression of procaspase 8, suggesting that fas/fasl pathway was activated in oridonin-induced cell apoptosis. |
2006-10-05 |
2023-08-12 |
human |
| Arnaud Jaubert, François Ichas, Laurence Bresson-Bepoldi. Signaling pathway involved in the pro-apoptotic effect of dopamine in the GH3 pituitary cell line. Neuroendocrinology. vol 83. issue 2. 2006-10-03. PMID:16785746. |
using flow cytometry, western blot, and confocal microscopy, we showed for the first time that da induced: (1) loss of mitochondrial potential; (2) relocation of bax to the mitochondria; (3) cytochrome c release; (4) caspase-3 activation, and (5) nuclear fragmentation, resulting in apoptosis. |
2006-10-03 |
2023-08-12 |
Not clear |
| P Marini, S Denzinger, D Schiller, S Kauder, S Welz, R Humphreys, P T Daniel, V Jendrossek, W Budach, C Belk. Combined treatment of colorectal tumours with agonistic TRAIL receptor antibodies HGS-ETR1 and HGS-ETR2 and radiotherapy: enhanced effects in vitro and dose-dependent growth delay in vivo. Oncogene. vol 25. issue 37. 2006-09-28. PMID:16636678. |
induction of apoptosis after combined treatment with trail receptor antibodies hgs-etr1 and/or hgs-etr2 (0.01, 0.1, 1.0 mg/ml) and irradiation with 2, 5 or 10 gy was determined by fluorescence microscopy and western blot analysis of caspase-8 and parp. |
2006-09-28 |
2023-08-12 |
mouse |
| Priya Weerasinghe, Sarathi Hallock, Shou-Ching Tang, Benjamin Trump, Andrejs Liepin. Sanguinarine overcomes P-glycoprotein-mediated multidrug-resistance via induction of apoptosis and oncosis in CEM-VLB 1000 cells. Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie. vol 58. issue 1. 2006-09-26. PMID:16735106. |
the cell death processes of apoptosis and oncosis in cem-vlb 1000 and cem-t4 cell lines were found to be qualitatively similar when assessed by light microscopy, terminal deoxynucleotidyl transferase (tdt) end-labeling, annexin-v-binding, trypan blue exclusion and western blot analysis. |
2006-09-26 |
2023-08-12 |
human |
| Li-Hong Fan, Kun-Zheng Wang, Bin Cheng, Chun-Sheng Wang, Xiao-Qian Dan. Anti-apoptotic and neuroprotective effects of Tetramethylpyrazine following spinal cord ischemia in rabbits. BMC neuroscience. vol 7. 2006-09-20. PMID:16774675. |
apoptosis was measured quantitatively by the terminal transferase utp nick end-labeling (tunel) method and confirmed by electron microscopic examination, the expression of bax and bcl-2 was immunohistochemically evaluated and quantified by western blot analysis. |
2006-09-20 |
2023-08-12 |
Not clear |
| Meng Mao, Yimin Hua, Xiangning Jiang, Lihua Li, Li Zhang, Dezhi M. Expression of tumor necrosis factor alpha and neuronal apoptosis in the developing rat brain after neonatal stroke. Neuroscience letters. vol 403. issue 3. 2006-09-01. PMID:16797840. |
we studied the expression and distribution of tnfalpha and neuronal apoptosis in a postnatal day 10 rat mcao model using reverse transcriptase-polymerase chain reaction (rt-pcr), western blot, immunohistochemistry, fluorescence double-labeling, and terminal deoxynucleotidyl transferase biotin-dutp nick end labeling (tunel) analyses. |
2006-09-01 |
2023-08-12 |
rat |
| Amr Y Esmat, Catherine Tomasetto, Marie-Christine Ri. Cytotoxicity of a natural anthraquinone (Aloin) against human breast cancer cell lines with and without ErbB-2: topoisomerase IIalpha coamplification. Cancer biology & therapy. vol 5. issue 1. 2006-08-23. PMID:16357514. |
this was demonstrated by flow cytometric analysis, fluorescence microscopy and western blot analysis, which revealed that aloin at higher concentrations caused a reduction in the proportion of cells undergoing mitosis by induction of apoptosis, inhibition of topo ii alpha protein expression and downregulation of cyclin b1 protein expression in mcf-7 cell line, whereas erbb-2 protein expression was not affected. |
2006-08-23 |
2023-08-12 |
human |
| Zhen Xian Du, Hai Yan Zhang, Da Xin Gao, Hua Qin Wang, Yong Jun Li, Guo Liang Li. Antisurvivin oligonucleotides inhibit growth and induce apoptosis in human medullary thyroid carcinoma cells. Experimental & molecular medicine. vol 38. issue 3. 2006-08-18. PMID:16819281. |
in tt cells, we confirmed survivin expression and its down-regulation by asodns using rt-pcr and western blot analyses, and investigated effects of asodns on viability and growth by mtt assay and apoptosis by apoptotic analyses including dna laddering assay, acridine orange/ethidium bromide staining and flow cytometric cell cycle analysis. |
2006-08-18 |
2023-08-12 |
human |
| Arabinda Das, Dena P Garner, Angelo M Del Re, John J Woodward, D Maneesh Kumar, Neeraj Agarwal, Naren L Banik, Swapan K Ra. Calpeptin provides functional neuroprotection to rat retinal ganglion cells following Ca2+ influx. Brain research. vol 1084. issue 1. 2006-08-10. PMID:16600192. |
western blot analyses showed an increase in activities of calpain and caspase-12, upregulation of bax:bcl-2 ratio, release of cytochrome c from mitochondria, and increase in caspase-9 and caspase-3 activities during apoptosis. |
2006-08-10 |
2023-08-12 |
rat |
| Kongming Wu, Mark D'Amico, Chenguang Wang, Chris Albanese, Richard G Pestell, Sridhar Man. A study of cytotoxic synergy of UCN-01 and flavopiridol in syngeneic pair of cell lines. Investigational new drugs. vol 23. issue 4. 2006-07-27. PMID:16012789. |
flavopiridol and ucn-01 augmented apoptosis in hela-s cells (as compared with hela-v cells) as measured by caspase-3 cellular activity assay, dna fragmentation and parp cleavage by western blot. |
2006-07-27 |
2023-08-12 |
human |
| Declan A Healy, Padraig J Daly, Neil G Docherty, Madeline Murphy, John M Fitzpatrick, R William G Watso. Heat shock-induced protection of renal proximal tubular epithelial cells from cold storage and rewarming injury. Journal of the American Society of Nephrology : JASN. vol 17. issue 3. 2006-07-27. PMID:16421224. |
heat shock was induced by incubation of cells at 42 degrees c for 1 h. altered protein expression was measured by western blot, and cell viability and apoptosis were measured by propidium iodide dna staining using flow cytometry. |
2006-07-27 |
2023-08-12 |
human |
| Hee Jun Cho, Jin Koo Kim, Kwang Dong Kim, Hyun Kyung Yoon, Mi-Young Cho, Yuk Pheel Park, Jun Ho Jeon, Eun Sik Lee, Seok-Soo Byun, Heon Man Lim, Eun Young Song, Jong-Seok Lim, Do-Young Yoon, Hee Gu Lee, Yong-Kyung Cho. Upregulation of Bcl-2 is associated with cisplatin-resistance via inhibition of Bax translocation in human bladder cancer cells. Cancer letters. vol 237. issue 1. 2006-07-26. PMID:16009487. |
western blot analysis of subcellular fractions showed that cisplatin induced redistribution of bax and cytochrome c. thus, cisplatin causes apoptosis in a death receptor-independent and mitochondria-dependent fashion in t24 cells. |
2006-07-26 |
2023-08-12 |
human |
| Hui-Lu Lin, Jai-Sing Yang, Jen-Hung Yang, Seng-Sheen Fan, Wen-Cheng Chang, Yu-Ching Li, Jing-Gung Chun. The role of Ca2+ on the DADS-induced apoptosis in mouse-rat hybrid retina ganglion cells (N18). Neurochemical research. vol 31. issue 3. 2006-07-20. PMID:16733814. |
cell viability, cell cycle analysis, reactive oxygen species (ros), ca2+ production, mitochondria membrane potential, apoptosis induction, associated gene expression and caspases-3 activity were examined by flow cytometric assay and/or western blot. |
2006-07-20 |
2023-08-12 |
human |
| Xiao M Androulakis, Stephanie J Muga, Feng Chen, Youssouf Koita, Boubacar Toure, Michael J Wargovic. Chemopreventive effects of Khaya senegalensis bark extract on human colorectal cancer. Anticancer research. vol 26. issue 3B. 2006-07-20. PMID:16821623. |
the diphenyl-2-picrylhydrazyl (dpph)- free radical activity and the total phenolic content of ksbe were measured, followed by an investigation of cell growth inhibition, cox and prostaglandin e 2 (pge2) suppression, as well as apoptosis by western blot analysis and elisa. |
2006-07-20 |
2023-08-12 |
human |
| Chi-Hsiao Yeh, Tzu-Ping Chen, Chieh-Hung Lee, Yi-Chen Wu, Yu-Min Lin, Pyng Jing Li. Inhibition of poly(adp-ribose) polymerase reduces cardiomyocytic apoptosis after global cardiac arrest under cardiopulmonary bypass. Shock (Augusta, Ga.). vol 25. issue 2. 2006-07-18. PMID:16525356. |
the reperfused hearts were harvested and studied for evidence of apoptosis using the tunel method and western blot analyses. |
2006-07-18 |
2023-08-12 |
Not clear |
| Krista Erkkila, Sauli Kyttanen, Marten Wikstrom, Kimmo Taari, Amiya P Sinha Hikim, Ronald S Swerdloff, Leo Dunke. Regulation of human male germ cell death by modulators of ATP production. American journal of physiology. Endocrinology and metabolism. vol 290. issue 6. 2006-07-13. PMID:16403780. |
here, we induced human male germ cell apoptosis (detected by southern blot analysis of dna fragmentation, tunel, activation of caspases-3 and -9, and electron microscopy) by incubating seminiferous tubule segments under hormone- and serum-free conditions. |
2006-07-13 |
2023-08-12 |
human |
| Rong Hu, Shufeng Zhou, Xiaotian L. Altered Bcl-2 and Bax expression is associated with cultured first trimester human cytotrophoblasts apoptosis induced by hypoxia. Life sciences. vol 79. issue 4. 2006-07-11. PMID:16499934. |
cellular apoptosis was monitored by tunel and annexin v binding, and the expression of bcl-2 and bax was determined by western blot analysis. |
2006-07-11 |
2023-08-12 |
human |