| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Shun-Lai Li, Zih-Ning Huang, Hsiao-Hui Hsieh, Wen-Chun Yu, Win-Yu Tzeng, Guo-Yang Lee, Yi-Peng Chen, Chia-Yu Chang, Jiunn-Jye Chu. The augmented anti-tumor effects of Antrodia camphorata co-fermented with Chinese medicinal herb in human hepatoma cells. The American journal of Chinese medicine. vol 37. issue 4. 2009-11-16. PMID:19655414. |
we measured in vitro cell proliferation, percentage of apoptosis, population distribution of cell cycles, western blot analysis of multiple drugs resistance-1 (mdr-1), and apoptosis-related proteins in hepg2 cells treated with three different preparations of a. camphorate extracts. |
2009-11-16 |
2023-08-12 |
human |
| Liming Shen, Qiong Liu, Jiazuan Ni, Guangyan Hon. A proteomic investigation into the human cervical cancer cell line HeLa treated with dicitratoytterbium (III) complex. Chemico-biological interactions. vol 181. issue 3. 2009-11-10. PMID:19632212. |
western blot analysis showed that [ybcit2](3-)-induced apoptosis was accompanied by the activation of caspase-9 and specific proteolytic cleavage of parp, leading to an increase in the pro-apoptotic protein bax and a decrease in the anti-apoptotic protein bcl-2. |
2009-11-10 |
2023-08-12 |
human |
| Sonia Perales, M José Alejandre, Rogelio Palomino-Morales, Carolina Torres, Jose Iglesias, Ana Linare. Effect of oxysterol-induced apoptosis of vascular smooth muscle cells on experimental hypercholesterolemia. Journal of biomedicine & biotechnology. vol 2009. 2009-11-10. PMID:19727411. |
the quantitative real-time reverse transcriptase-polymerase chain reaction and the immunoblotting western blot analysis showed that 25-hydroxycholesterol produces apoptosis in smcs, mediated by a high increase in bax protein and bax gene expression. |
2009-11-10 |
2023-08-12 |
chicken |
| Jian-ye Zhang, Li-yang Tao, Yong-ju Liang, Yan-yan Yan, Chun-ling Dai, Xue-kui Xia, Zhi-gang She, Yong-cheng Lin, Li-wu F. Secalonic acid D induced leukemia cell apoptosis and cell cycle arrest of G(1) with involvement of GSK-3beta/beta-catenin/c-Myc pathway. Cell cycle (Georgetown, Tex.). vol 8. issue 15. 2009-10-30. PMID:19571678. |
annexin v-fitc/pi assay and western blot indicated that secalonic acid d induced apoptosis in hl60 and k562 cells. |
2009-10-30 |
2023-08-12 |
Not clear |
| Chie Nishioka, Takayuki Ikezoe, Jing Yang, Akihito Yokoyam. Inhibition of MEK signaling enhances the ability of cytarabine to induce growth arrest and apoptosis of acute myelogenous leukemia cells. Apoptosis : an international journal on programmed cell death. vol 14. issue 9. 2009-10-21. PMID:19548087. |
azd6244 effectively blocked arac-induced mek/erk activation and enhanced its ability to induce growth arrest and apoptosis of nb4 and hl60 cells in parallel with induction of dna damage as measured by detection of gamma-h2ax by western blot analysis, resulting in enhanced expression of p21( waf1 ) and downregulation of c-myc and bcl-xl in these cells. |
2009-10-21 |
2023-08-12 |
Not clear |
| Sung-Ho Kook, Young-Ok Son, Seong-Kyu Han, Hyung-Soon Lee, Beom-Tae Kim, Yong-Suk Jang, Ki-Choon Choi, Keun-Soo Lee, So-Soon Kim, Ji-Young Lim, Young-Mi Jeon, Jong-Ghee Kim, Jeong-Chae Le. Epstein-Barr virus-infected Akata cells are sensitive to histone deacetylase inhibitor TSA-provoked apoptosis. Journal of biochemistry and molecular biology. vol 38. issue 6. 2009-10-19. PMID:16336792. |
western blot analysis showed that caspase-dependent pathways are involved in the tsa-induced apoptosis of ebv-infected akata cells. |
2009-10-19 |
2023-08-12 |
Not clear |
| Xian-Kun Tu, Wei-Zhong Yang, Song-Sheng Shi, Chun-Hua Wang, Chun-Mei Che. Neuroprotective effect of baicalin in a rat model of permanent focal cerebral ischemia. Neurochemical research. vol 34. issue 9. 2009-10-19. PMID:19294503. |
neuronal apoptosis was determined by tunel staining and western blot. |
2009-10-19 |
2023-08-12 |
rat |
| Valeria Milani, Monika Lorenz, Marc Weinkauf, Malte Rieken, Alessandro Pastore, Martin Dreyling, Rolf Issel. Combination of hyperthermia and bortezomib results in additive killing in mantle cell lymphoma cells. International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group. vol 25. issue 4. 2009-10-16. PMID:19670095. |
treated tumor cells were assessed for proliferation using the wst-1 assay and for apoptosis by annexin v staining, while heat shock protein (hsp) levels were determined following western blot analysis. |
2009-10-16 |
2023-08-12 |
Not clear |
| Qiang Zhang, Xin-Huai Zhao, Zhu-Jun Wan. Cytotoxicity of flavones and flavonols to a human esophageal squamous cell carcinoma cell line (KYSE-510) by induction of G2/M arrest and apoptosis. Toxicology in vitro : an international journal published in association with BIBRA. vol 23. issue 5. 2009-10-13. PMID:19397994. |
furthermore, the expression of genes related to cell cycle arrest and apoptosis was assessed by oligonucleotide microarray, real-time rt-pcr and western blot. |
2009-10-13 |
2023-08-12 |
human |
| G Vinothini, R Senthil Murugan, S Nagin. Evaluation of molecular markers in a rat model of mammary carcinogenesis. Oncology research. vol 17. issue 10. 2009-09-25. PMID:19725228. |
we analyzed dmba-induced changes in the expression of cyp isoforms (cyp1a1 and 1b1) involved in dmba metabolism, markers of oxidative stress (4hne, hel, and 8-ohdg), cell survival and proliferation (pcna, nf-kappab-p50, nf-kappab-p65, gst-p, and p53), apoptosis (bcl-2, bax, caspases, apaf-1, cytochrome c, and fas), invasion (upa, mmp-2, mmp-9, timp-2, and reck), and angiogenesis (vegf, vegf-r1, hif-1alpha, and plgf) by immunohistochemical localization, western blot, and reverse transcriptase-polymerase chain reaction (rt-pcr) analysis. |
2009-09-25 |
2023-08-12 |
human |
| Gabriella Marfe, Bruna Pucci, Luisa De Martino, Filomena Fiorito, Carla Di Stefano, Manuela Indelicato, Michele Aventaggiato, Matteo A Russo, Marco Tafan. Heat-shock pretreatment inhibits sorbitol-induced apoptosis in K562, U937 and HeLa cells. International journal of cancer. vol 125. issue 9. 2009-09-15. PMID:19598258. |
apoptosis was evaluated by dna fragmentation, whereas caspase-9,-3 activation, cytochrome c release and heat-shock protein70 (hsp70) were assayed by western blot. |
2009-09-15 |
2023-08-12 |
Not clear |
| Ajaikumar B Kunnumakkara, Parmeswaran Diagaradjane, Preetha Anand, Kuzhuvelil B Harikumar, Harikumar B Kuzhuvelil, Amit Deorukhkar, Juri Gelovani, Sushovan Guha, Sunil Krishnan, Bharat B Aggarwa. Curcumin sensitizes human colorectal cancer to capecitabine by modulation of cyclin D1, COX-2, MMP-9, VEGF and CXCR4 expression in an orthotopic mouse model. International journal of cancer. vol 125. issue 9. 2009-09-15. PMID:19623659. |
the effect of curcumin on proliferation of crc cell lines was examined by mitochondrial dye-uptake assay, apoptosis by esterase staining, nuclear factor-kappab (nf-kappab) by electrophoretic mobility shift assay and gene expression by western blot analysis. |
2009-09-15 |
2023-08-12 |
mouse |
| Yan Chen, Qing Wu, Guo-hui Cui, Yi-quan Chen, Rui L. Deguelin blocks cells survival signal pathways and induces apoptosis of HL-60 cells in vitro. International journal of hematology. vol 89. issue 5. 2009-09-09. PMID:19455392. |
apoptosis was detected by annexin v-fitc apoptosis detection kit and transmission electron microscopy (tem), expression of p-akt, bcl-2 and surviving in hl-60 cells was checked by western blot. |
2009-09-09 |
2023-08-12 |
human |
| Tianli Fan, Guozhong Jiang, Zhenhe Suo, Hongtao Liu, Peirong Xu, Zhenyu Ji, Lirong Zhang, Guanrui Yan. Down-regulation of the apoptosis-inducing factor or Bcl-2 inhibitor of transcription by RNA interference can alleviate TAp63gamma-induced apoptosis in esophageal squamous carcinoma EC9706 cells. International journal of oncology. vol 35. issue 2. 2009-09-01. PMID:19578750. |
in addition, it was found with western blot that aif and bit1 were released into cytosol from mitochondria, and aif was further translocated into nucleus, during the stage of tap63gamma-induced cell apoptosis. |
2009-09-01 |
2023-08-12 |
human |
| Zhi Jiang, Bao-An Chen, Guo-Hua Xia, Qiang Wu, Yu Zhang, Tie-Yan Hong, Wei Zhang, Jian Cheng, Feng Gao, Li-Jie Liu, Xiao-Mao Li, Xue-Mei Wan. The reversal effect of magnetic Fe3O4 nanoparticles loaded with cisplatin on SKOV3/DDP ovarian carcinoma cells. International journal of nanomedicine. vol 4. 2009-08-26. PMID:19516889. |
the expression of apoptosis associated gene bcl-2 mrna was detected by reverse transcription polymerase chain reaction and the expressions of mdr1, lung resistance-related protein (lrp), and p-glycoprotein (p-gp) genes were studied by western blot. |
2009-08-26 |
2023-08-12 |
Not clear |
| Hong-Qing Zhuang, Jian Sun, Zhi-Yong Yuan, Jun Wang, Lu-Jun Zhao, Ping Wang, Xiu-Bao Ren, Chang-Li Wan. Radiosensitizing effects of gefitinib at different administration times in vitro. Cancer science. vol 100. issue 8. 2009-08-25. PMID:19432883. |
cell apoptosis and cell-cycle distribution were investigated using flow cytometry; meanwhile, the expression of p21, cdc25c, bcl-2, bax, rad51 and phosphorylated dna-pkcs (phospho-dna-pk) after 6 gy irradiation and/or gefitinib were determined by western blot analysis. |
2009-08-25 |
2023-08-12 |
Not clear |
| Cheng-Yun Liu, Ping-An Chang, Yi-Jun W. Trichlorfon induces apoptosis in SH-SY5Y neuroblastoma cells via the endoplasmic reticulum? Chemico-biological interactions. vol 181. issue 1. 2009-08-18. PMID:19631781. |
western blot analysis indicated decreased expression of caspase-12 and increased activated caspase-12 in trichlorfon-treated cells compared to a control, suggesting that trichlorfon may induce apoptosis in sh-sy5y partly via the endoplasmic reticulum. |
2009-08-18 |
2023-08-12 |
human |
| Zhitao Wang, Quanjun Deng, Xiaohui Zhang, Jianning Zhan. Treatment of injured neurons with bone marrow stem cells cotransfected by hTERT and Ad-BDNF in vitro. Journal of molecular neuroscience : MN. vol 38. issue 3. 2009-08-17. PMID:19459071. |
the anti-injury effect of rbmscs transfected by htert and ad-bdnf was detected by western blot for neural apoptosis gene map2 and nf-kappab and lactic dehydrogenase released by injured neurons. |
2009-08-17 |
2023-08-12 |
human |
| Dayna J Groskreutz, Martha M Monick, Ellen C Babor, Toru Nyunoya, Steven M Varga, Dwight C Look, Gary W Hunninghak. Cigarette smoke alters respiratory syncytial virus-induced apoptosis and replication. American journal of respiratory cell and molecular biology. vol 41. issue 2. 2009-08-11. PMID:19131644. |
western blot detection of cleaved caspases 3 and 7 showed less apoptosis when cells were treated with cigarette smoke before viral infection. |
2009-08-11 |
2023-08-12 |
Not clear |
| C Chen, P Tang, J Yue, P Ren, X Liu, X Zhao, Z Y. Effect of siRNA targeting HIF-1alpha combined L-ascorbate on biological behavior of hypoxic MiaPaCa2 cells. Technology in cancer research & treatment. vol 8. issue 3. 2009-08-11. PMID:19445542. |
then, we observed the expression of hif-1alpha mrna and protein, the proliferation, apoptosis, and migration of miapaca2 cells by real-time pcr, western blot, mtt, tunel, and transwell assay, respectively. |
2009-08-11 |
2023-08-12 |
human |