| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Huiqing Sun, Lei Li, Feng Zhou, Lin Zhu, Kaifu Ke, Xiang Tan, Wei Xu, Ying Rui, Heyi Zheng, Zhengming Zhou, Huiguang Yan. The member of high temperature requirement family HtrA2 participates in neuronal apoptosis after intracerebral hemorrhage in adult rats. Journal of molecular histology. vol 44. issue 4. 2014-04-18. PMID:23413020. |
we analyzed the relationship of htra2 with x-linked inhibitor of apoptosis protein (xiap) in pc12 cells by western blot, immunofluorescence and co-immunoprecipitation. |
2014-04-18 |
2023-08-12 |
rat |
| Stewart R Carter, Anita Zahs, Jessica L Palmer, Lu Wang, Luis Ramirez, Richard L Gamelli, Elizabeth J Kovac. Intestinal barrier disruption as a cause of mortality in combined radiation and burn injury. Shock (Augusta, Ga.). vol 40. issue 4. 2014-04-16. PMID:24045418. |
intestinal histology was evaluated, and apoptosis was quantified using histone-associated dna fragmentation enzyme-linked immunosorbent assay and western blot for caspase-3 and caspase-8. |
2014-04-16 |
2023-08-12 |
Not clear |
| Mohammad Reza Ahmadianpour, Parviz Abdolmaleki, Seyed Javad Mowla, Saman Hosseinkhan. Static magnetic field of 6 mT induces apoptosis and alters cell cycle in p53 mutant Jurkat cells. Electromagnetic biology and medicine. vol 32. issue 1. 2014-04-15. PMID:23320430. |
exposure of human p53 mutant jurkat cells to 6 mt smf resulted in apoptosis, which was detected by luminometric and flow cytometric analysis also, phosphorylated atm and e2f1 proteins were detected by western blot analysis. |
2014-04-15 |
2023-08-12 |
human |
| Feng Zhang, Zhiyi Zhang, Zhiyu Li. Effects of Huaier aqueous extract on proliferation and apoptosis in the melanoma cell line A875. Acta histochemica. vol 115. issue 7. 2014-04-15. PMID:23601357. |
the cell cycle distribution, and apoptosis levels were analyzed by flow cytometry, and western blot was used to test the apoptotic pathways. |
2014-04-15 |
2023-08-12 |
Not clear |
| Rong Sun, Ke Wang, Dongdong Wu, Xiaoyu Li, Yangbing O. Protective effect of paeoniflorin against glutamate-induced neurotoxicity in PC12 cells via Bcl-2/Bax signal pathway. Folia neuropathologica. vol 50. issue 3. 2014-04-14. PMID:23023341. |
pc12 cells were cultured in vitro, cell viability was assessed by mtt assay, cell apoptosis as well as mitochondrial membrane potential (mmp) were detected by flow cytometric analysis and the expression profiles of apoptosis-related proteins including bcl-2 and bax were investigated by western blot. |
2014-04-14 |
2023-08-12 |
rat |
| Bing-Ying Ho, Chun-Hung Lin, Maria Karmella Apaya, Wen-Wan Chao, Lie-Fen Shyu. Silibinin and Paclitaxel Cotreatment Significantly Suppress the Activity and Lung Metastasis of Triple Negative 4T1 Mammary Tumor Cell in Mice. Journal of traditional and complementary medicine. vol 2. issue 4. 2014-04-09. PMID:24716145. |
flow cytometry and western blot analyses demonstrated that both drugs deregulated cell-cycle mediators and induced apoptosis in 4t1 cells. |
2014-04-09 |
2023-08-13 |
mouse |
| Doris Mangiaracina Benbrook, Suresh Guruswamy, Yuhong Wang, Zhongjie Sun, Altaf Mohammed, Yuting Zhang, Qian Li, Chinthalapally V Ra. Chemoprevention of colon and small intestinal tumorigenesis in APC(min/+) mice by SHetA2 (NSC721689) without toxicity. Cancer prevention research (Philadelphia, Pa.). vol 6. issue 9. 2014-04-03. PMID:23852423. |
western blot analysis also showed sheta2 induction of e-cadherin, bax, and caspase-3 cleavage along with reduction in bcl-2, cox-2, and vegf, consistent with sheta2 regulation of apoptosis, inflammation, and angiogenesis. |
2014-04-03 |
2023-08-12 |
mouse |
| Jun Zhou, Huiyong Hu, Jingpei Long, Fang Wan, Lili Li, Suzhan Zhang, Yuenian E Shi, Yiding Che. Vitexin 6, a novel lignan, induces autophagy and apoptosis by activating the Jun N-terminal kinase pathway. Anti-cancer drugs. vol 24. issue 9. 2014-03-18. PMID:23965728. |
the expression of proteins that regulate apoptosis and autophagy was determined using western blot analysis. |
2014-03-18 |
2023-08-12 |
Not clear |
| Mingyang Zhang, Haiyan Shan, Yaoqi Wang, Tao Wang, Weili Liu, Long Wang, Lu Zhang, Pan Chang, Wenwen Dong, Xiping Chen, Luyang Ta. The expression changes of cystathionine-β-synthase in brain cortex after traumatic brain injury. Journal of molecular neuroscience : MN. vol 51. issue 1. 2014-03-12. PMID:23315129. |
in addition, western blot detection showed that the third day postinjury was also the apoptosis peak indicated by the elevated expression of caspase-3. |
2014-03-12 |
2023-08-12 |
mouse |
| X Li, Z Li, W Zhou, X Xing, L Huang, L Tian, J Chen, C Chen, X Ma, Z Yan. Overexpression of 4EBP1, p70S6K, Akt1 or Akt2 differentially promotes Coxsackievirus B3-induced apoptosis in HeLa cells. Cell death & disease. vol 4. 2014-03-12. PMID:24030155. |
next, after cvb3 infection, apoptosis in different groups was determined by flow cytometry; the expressions of bim, bax, caspase-9 and caspase-3 were examined by real-time fluorescence quantitative pcr and western blot analysis; the expression of cvb3 mrna and viral capsid protein vp1 were also analyzed by real-time fluorescence quantitative pcr, western blot analysis and immunofluorescence, respectively. |
2014-03-12 |
2023-08-12 |
Not clear |
| Liboria Siena, Elisabetta Pace, Maria Ferraro, Caterina Di Sano, Mario Melis, Mirella Profita, Mario Spatafora, Mark Gjomarka. Gemcitabine sensitizes lung cancer cells to Fas/FasL system-mediated killing. Immunology. vol 141. issue 2. 2014-03-11. PMID:24128051. |
apoptosis of fasl-expressing cells was evaluated by flow cytometry, and caspase-8 and caspase-3 activation by western blot and a colorimetric assay. |
2014-03-11 |
2023-08-12 |
Not clear |
| Jin Rhyu, Min Sook Kim, Mi-Kyoung You, Mi-Ae Bang, Hyeon-A Ki. Pear pomace water extract inhibits adipogenesis and induces apoptosis in 3T3-L1 adipocytes. Nutrition research and practice. vol 8. issue 1. 2014-03-10. PMID:24611103. |
the effects of pear pomace extract on cell viability and the anti-adipogenic and proapoptotic effects were investigated via mtt assay, oil red o staining, western blot analysis and apoptosis assay. |
2014-03-10 |
2023-08-12 |
Not clear |
| J Tian, Y X Duan, C Y Bei, J Che. Calycosin induces apoptosis by upregulation of RASD1 in human breast cancer cells MCF-7. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. vol 45. issue 8. 2014-03-03. PMID:23609007. |
to provide insight into the functions of rasd1 signaling pathway in calycosin-induced apoptosis, the expression of bcl-2, bax, and rasd1 in calycosin-treated cells were determined by western blot assay. |
2014-03-03 |
2023-08-12 |
human |
| Dechao Kong, Tiansheng Zheng, Ming Zhang, Daode Wang, Shihao Du, Xiang Li, Jiahu Fang, Xiaojian Ca. Static mechanical stress induces apoptosis in rat endplate chondrocytes through MAPK and mitochondria-dependent caspase activation signaling pathways. PloS one. vol 8. issue 7. 2014-03-03. PMID:23894471. |
western blot analysis revealed that static load-induced chondrocyte apoptosis was accompanied by increased phosphorylation of c-jun n-terminal kinase (jnk), extracellular signal-regulated kinase 1/2 (erk1/2), and p38 mitogen-activated protein kinase (mapk). |
2014-03-03 |
2023-08-12 |
rat |
| Ryo Endo, Tomomi Notsu, Mutsuo Mishima, Kumi Morikawa, Peili Li, Nobuhito Ikeda, Haruaki Ninomiya, Yasuaki Shirayoshi, Ichiro Hisatom. Bepridil Suppresses Apoptosis in HL-1 Cardiac Atrial Myocytes Expressing Mutant E334K cMyBPC. Yonago acta medica. vol 56. issue 4. 2014-02-27. PMID:24574578. |
bepridil was compared with amiodarone, and its effects on the expression of pro- and anti-apoptotic protein and apoptosis of hl-1 cells expressing mutant e334k mybpc-green fluorescent protein (gfp) was analyzed using western blot and a flow cytometer. |
2014-02-27 |
2023-08-12 |
Not clear |
| C Liu, W Duan, R Li, S Xu, L Zhang, C Chen, M He, Y Lu, H Wu, H Pi, X Luo, Y Zhang, M Zhong, Z Yu, Z Zho. Exposure to bisphenol A disrupts meiotic progression during spermatogenesis in adult rats through estrogen-like activity. Cell death & disease. vol 4. 2014-02-25. PMID:23788033. |
this was concomitant with a disruption in the progression of meiosis i and the persistence of meiotic dna strand breaks in pachytene spermatocytes,and the ataxia-telangiectasia-mutated and checkpoint kinase 2 signal pathway was also activated; eventually, germ cell apoptosis was triggered as evaluated by terminal dutp nick-end labeling assay and western blot for caspase 3. |
2014-02-25 |
2023-08-12 |
rat |
| Xi-Lan Tang, Jian-Xun Liu, Peng Li, Wei Dong, Lei Li, Yong-Qiu Zheng, Jin-Cai Ho. [Protective effect of succinic acid on primary cardiomyocyte hypoxia/reoxygenation injury]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 38. issue 21. 2014-02-25. PMID:24494565. |
furthermore, flow cytometry and western blot were conducted to detect the effect of succinic acid on cardiomyocyte apoptosis, cleaved caspase-3 and p-akt, and discuss the protective effect of succinic acid on primary cardiomyocyte hypoxia/reoxygenation injury of primary cardiomyocytes from neonatal sd rats. |
2014-02-25 |
2023-08-12 |
rat |
| P F Jiang, T Zhu, J D Gao, F Gao, S S Mao, W T Zhao, W Z Gu, H M Y. The effect of maternal infection on cognitive development and hippocampus neuronal apoptosis, proliferation and differentiation in the neonatal rats. Neuroscience. vol 246. 2014-02-24. PMID:23597829. |
terminal deoxynucleotidyl transferase dutp nick end labeling assay was used to determine neuronal apoptosis, immunostaining was conducted to assess neurogenesis, and western blot for extracellular signal-regulated kinase (erk), cyclic amp responsive element-binding protein (creb) and brain-derived neurotrophic factor (bdnf) expression in the hippocampus. |
2014-02-24 |
2023-08-12 |
rat |
| Virginia Lezcano, Claudia Gentili, Ana Russo de Bolan. Role of PTHrP in human intestinal Caco-2 cell response to oxidative stress. Biochimica et biophysica acta. vol 1833. issue 12. 2014-02-24. PMID:23845990. |
cells were exposed to an oxidative insult in the form of hydrogen peroxide to induce apoptosis, which leads to a 50% loss of cell viability determined by mts assay, morphological changes observed under fluorescence microscopy and western blot analysis. |
2014-02-24 |
2023-08-12 |
human |
| Qiuhua Chen, Yingzi Huang, Yi Yang, Haibo Qi. Acid‑induced cell injury and death in lung epithelial cells is associated with the activation of mitogen‑activated protein kinases. Molecular medicine reports. vol 8. issue 2. 2014-02-13. PMID:23784034. |
cell apoptosis was detected as changes in the levels of capase‑3, bad and fas by western blot analysis and the number of apoptotic cells by using annexin v/propidium iodide (pi) staining. |
2014-02-13 |
2023-08-12 |
Not clear |