| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Shuang Zhang, Min Yu, Hongxin Deng, Guobo Shen, Yuquan We. Polyclonal rabbit anti-human ovarian cancer globulins inhibit tumor growth through apoptosis involving the caspase signaling. Scientific reports. vol 4. 2014-08-29. PMID:24828460. |
western blot analysis was conducted, which indicated that poly ab inhibited cancer cells through apoptosis involving the caspase signaling pathway including caspase-3 and caspase-9. |
2014-08-29 |
2023-08-13 |
mouse |
| María Celeste Robert, Giulia Furlan, Natalia Rosso, Sabrina Eliana Gambaro, Faina Apitsionak, Eleonora Vianello, Claudio Tiribelli, Silvia Gazzi. Alterations in the cell cycle in the cerebellum of hyperbilirubinemic Gunn rat: a possible link with apoptosis? PloS one. vol 8. issue 11. 2014-08-26. PMID:24223883. |
we explored the effect of sustained spontaneous hyperbilirubinemia on cell cycle progression and apoptosis in whole cerebella dissected from 9 day old gunn rat by real time pcr, western blot and facs analysis. |
2014-08-26 |
2023-08-12 |
rat |
| Chunmei Li, Myeong-Hyeon Wan. Aristolochia debilis Sieb. et Zucc. induces apoptosis and reactive oxygen species in the HT-29 human colon cancer cell line. Cancer biotherapy & radiopharmaceuticals. vol 28. issue 10. 2014-08-25. PMID:23848946. |
reverse transcription-polymerase chain reaction and western blot analyses were used to determine changes in the expression of mitochondria-dependent apoptosis markers (bax and bcl-2). |
2014-08-25 |
2023-08-12 |
human |
| Ravikanth Danda, Gopinath Krishnan, Kalaivani Ganapathy, Uma Maheswari Krishnan, Khetan Vikas, Sailaja Elchuri, Nivedita Chatterjee, Subramanian Krishnakuma. Targeted expression of suicide gene by tissue-specific promoter and microRNA regulation for cancer gene therapy. PloS one. vol 8. issue 12. 2014-08-25. PMID:24391761. |
the cell proliferation was measured by mtt assay, apoptosis was measured by probing cleaved caspase3, epcam and tk expression were quantified by western blot. |
2014-08-25 |
2023-08-12 |
Not clear |
| Hong Seok Park, Sung Kyu Hong, Mi Mi Oh, Cheol Yong Yoon, Seong Jin Jeong, Seok Soo Byun, Jun Cheon, Sang Eun Lee, Du Geon Moo. Synergistic antitumor effect of NVP-BEZ235 and sunitinib on docetaxel-resistant human castration-resistant prostate cancer cells. Anticancer research. vol 34. issue 7. 2014-08-21. PMID:24982354. |
flow cytometry and western blot analysis of proteins related to apoptosis and cell survival axis were performed. |
2014-08-21 |
2023-08-13 |
human |
| Mobin Jamal, Azhar Masood, Rosetta Belcastro, Lianet Lopez, Jun Li, Jaques Belik, Robert P Jankov, A Keith Tanswel. Lipid hydroperoxide formation regulates postnatal rat lung cell apoptosis and alveologenesis. Free radical biology & medicine. vol 55. 2014-08-20. PMID:23195685. |
alveolar formation and physiological lung cell apoptosis were assessed by morphometry, immunohistochemistry, and western blot analyses on day 7 samples. |
2014-08-20 |
2023-08-12 |
rat |
| Jun Liu, Yazhou Yao, Huifang Ding, Renan Che. Oxymatrine triggers apoptosis by regulating Bcl-2 family proteins and activating caspase-3/caspase-9 pathway in human leukemia HL-60 cells. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 35. issue 6. 2014-08-19. PMID:24563336. |
the proteins involved in oxymatrine-induced apoptosis in hl-60 cells were also examined using western blot. |
2014-08-19 |
2023-08-12 |
human |
| Lior Drukker, Alexander Margulis, Malka Chaouat, Rubina Levitzki, Elena Maiorenko, Hannah Ben Bassa. Changes of PI3K/AKT/BCL2 signaling proteins in congenital Giant Nevi: melanocytes contribute to their increased survival and integrity. Journal of receptor and signal transduction research. vol 33. issue 6. 2014-08-18. PMID:24069951. |
we applied a model of cultured melanocytes from paired cgn and normal appearing skin, and western blot (wb) analyzed the expression and activation profile of survival and anti-apoptotic proteins of these signaling pathways, growth pattern, cell cycle and apoptosis. |
2014-08-18 |
2023-08-12 |
Not clear |
| Yong-Byung Chae, Moon-Moo Ki. Activation of p53 by spermine mediates induction of autophagy in HT1080 cells. International journal of biological macromolecules. vol 63. 2014-08-18. PMID:24189165. |
furthermore, western blot analyses demonstrated that spermine modulates the expression of proteins related to autophagy and apoptosis. |
2014-08-18 |
2023-08-12 |
human |
| Myeongjin Yi, Paramasivam Parthiban, Jiyoung Hwang, Xin Zhang, Hyunjin Jeong, Dong Ho Park, Dong-Kyoo Ki. Effect of a bispidinone analog on mitochondria‑mediated apoptosis in HeLa cells. International journal of oncology. vol 44. issue 1. 2014-08-18. PMID:24190603. |
the western blot analysis results suggested that analog 9 induced mitochondria-mediated apoptosis. |
2014-08-18 |
2023-08-12 |
human |
| Rahul Raghavan, Sanith Cheriyamundath, Joseph Madasser. 14-Deoxy-11,12-didehydroandrographolide inhibits proliferation and induces GSH-dependent cell death of human promonocytic leukemic cells. Journal of natural medicines. vol 68. issue 2. 2014-08-18. PMID:24458985. |
apoptosis induction was confirmed by dna laddering assay and western blot analysis using anti-caspase-3 protein antibody. |
2014-08-18 |
2023-08-12 |
human |
| Ahmed Kamal, N V Subba Reddy, V Lakshma Nayak, V Saidi Reddy, B Prasad, Vijaykumar D Nimbarte, Vunnam Srinivasulu, M V P S Vishnuvardhan, C Suresh Redd. Synthesis and biological evaluation of benzo[b]furans as inhibitors of tubulin polymerization and inducers of apoptosis. ChemMedChem. vol 9. issue 1. 2014-08-11. PMID:24203459. |
furthermore, detailed biological studies such as hoechst 33258 staining, dna fragmentation and caspase-3 assays, and western blot analyses with the pro-apoptotic protein bax and the anti-apoptotic protein bcl-2 also suggested that these compounds induce cell death by apoptosis. |
2014-08-11 |
2023-08-12 |
Not clear |
| Abida Arshad, Xuechai Chen, Zhenzhen Cong, Hong Qing, Yulin Den. TRPC1 protects dopaminergic SH-SY5Y cells from MPP+, salsolinol, and N-methyl-(R)-salsolinol-induced cytotoxicity. Acta biochimica et biophysica Sinica. vol 46. issue 1. 2014-08-04. PMID:24252728. |
mtt (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) assays, dapi (4',6-diamidino-2-phenylindole), fluorescein isothiocyanate-annexin-v/propidium iodide, western blot analysis, and jc-1 labeling revealed that the three indicated drugs could induce caspase-dependent, mitochondrial-mediated apoptosis. |
2014-08-04 |
2023-08-12 |
Not clear |
| Dan Goldowitz, Alexandre A Lussier, Julia K Boyle, Kaelan Wong, Scott L Lattimer, Candis Dubose, Lu Lu, Michael S Kobor, Kristin M Hamr. Molecular pathways underpinning ethanol-induced neurodegeneration. Frontiers in genetics. vol 5. 2014-07-31. PMID:25076964. |
in parallel, the levels of two histone modifications relevant to apoptosis, γh2ax and h3k14 acetylation, were examined in the cerebral cortex using protein blot analysis. |
2014-07-31 |
2023-08-13 |
mouse |
| Ketao Wang, Changlong Lin, Chengqin Wang, Qianqian Shao, Wenjuan Gao, Bingfeng Song, Lei Wang, Xiaobin Song, Xun Qu, Fengcai We. Silencing Kif2a induces apoptosis in squamous cell carcinoma of the oral tongue through inhibition of the PI3K/Akt signaling pathway. Molecular medicine reports. vol 9. issue 1. 2014-07-29. PMID:24248467. |
sirna vector was constructed, western blot analysis was used to determine rna interference and flow cytometry was used to determine promotion of tca8113 cell apoptosis. |
2014-07-29 |
2023-08-12 |
human |
| Yonggang Wang, Shanshan Zhou, Wanqing Sun, Kristen McClung, Yong Pan, Guang Liang, Yi Tan, Yunjie Zhao, Quan Liu, Jian Sun, Lu Ca. Inhibition of JNK by novel curcumin analog C66 prevents diabetic cardiomyopathy with a preservation of cardiac metallothionein expression. American journal of physiology. Endocrinology and metabolism. vol 306. issue 11. 2014-07-22. PMID:24714399. |
cardiac fibrosis, oxidative damage, endoplasmic reticulum stress, and cell apoptosis, examined by sirius red staining, western blot, and thiobarbituric acid assay, were also significantly increased in diabetic mice, all which were prevented by c66 or jnki treatment under diabetic conditions. |
2014-07-22 |
2023-08-13 |
mouse |
| Yan Peng, Sha Huang, Yan Wu, Biao Cheng, Xiaohu Nie, Hongwei Liu, Kui Ma, Jiping Zhou, Dongyun Gao, Changjiang Feng, Siming Yang, Xiaobing F. Platelet rich plasma clot releasate preconditioning induced PI3K/AKT/NFκB signaling enhances survival and regenerative function of rat bone marrow mesenchymal stem cells in hostile microenvironments. Stem cells and development. vol 22. issue 24. 2014-07-21. PMID:23885779. |
by using reverse transcription-polymerase chain reaction, immunofluorescence and western blot analyses, we showed that prcr preconditioning could alleviate the apoptosis of bm-mscs under stress conditions induced by hydrogen peroxide (h2o2) and serum deprivation by enhancing expression of vascular endothelial growth factor and platelet-derived growth factor (pdgf) via stimulation of the platelet-derived growth factor receptor (pdgfr)/pi3k/akt/nf-κb signaling pathways. |
2014-07-21 |
2023-08-12 |
rat |
| Wenjing Zhong, Xian Chen, Pingping Jiang, Jennifer M F Wan, Peng Qin, Alfred C H Y. Induction of endoplasmic reticulum stress by sonoporation: linkage to mitochondria-mediated apoptosis initiation. Ultrasound in medicine & biology. vol 39. issue 12. 2014-07-17. PMID:24063957. |
they were also consistent with another western blot assay that found, in sonoporated cells, a time-lapse increase of caspase-9 (a mitochondria-activated apoptosis initiator protein). |
2014-07-17 |
2023-08-12 |
Not clear |
| Min-Cheol Kang, Kil-Nam Kim, Sung-Myung Kang, Xiudong Yang, Eun-A Kim, Choon Bok Song, Jae-Woon Nah, Mi-Kyeong Jang, Jung-Suck Lee, Won-Kyo Jung, You-Jin Jeo. Protective effect of dieckol isolated from Ecklonia cava against ethanol caused damage in vitro and in zebrafish model. Environmental toxicology and pharmacology. vol 36. issue 3. 2014-07-15. PMID:24189014. |
it was observed that dieckol reduced cell apoptosis through activation of bcl-xl and parp, and down-regulation of bax and caspase-3 in western blot analyses. |
2014-07-15 |
2023-08-12 |
zebrafish |
| Anzhou Xia, Zhi Xue, Yong Li, Wei Wang, Jieyun Xia, Tiantian Wei, Jing Cao, Weidong Zho. Cardioprotective effect of betulinic Acid on myocardial ischemia reperfusion injury in rats. Evidence-based complementary and alternative medicine : eCAM. vol 2014. 2014-06-25. PMID:24963326. |
the expression of bcl-2 and bax and the apoptosis of cardiomyocytes were investigated with western blot and tunel assay, respectively. |
2014-06-25 |
2023-08-13 |
rat |