| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Zhiyong Wu, Feifeng Dai, Wei Ren, Huagang Liu, Bowen Li, Jinxing Chan. Angiotensin II induces apoptosis of human pulmonary microvascular endothelial cells in acute aortic dissection complicated with lung injury patients through modulating the expression of monocyte chemoattractant protein-1. American journal of translational research. vol 8. issue 1. 2016-04-12. PMID:27069537. |
western blot analysis was performed to evaluate the expression of mcp-1 and apoptosis related protein. |
2016-04-12 |
2023-08-13 |
human |
| Sahng-Wook Hahm, Jieun Park, Kun-Young Park, Yong-Suk Son, Hyungchul Ha. Extracts of Opuntia humifusa Fruits Inhibit the Growth of AGS Human Gastric Adenocarcinoma Cells. Preventive nutrition and food science. vol 21. issue 1. 2016-04-12. PMID:27069903. |
to elucidate the antiproliferative mechanisms of ohf in cancer cells, the expression of genes related to apoptosis and cell cycle arrest were determined with real-time pcr and western blot. |
2016-04-12 |
2023-08-13 |
human |
| Iyyappan Rajan, P R Jayasree, P R Manish Kuma. Zerumbone induces mitochondria-mediated apoptosis via increased calcium, generation of reactive oxygen species and upregulation of soluble histone H2AX in K562 chronic myelogenous leukemia cells. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 36. issue 11. 2016-04-06. PMID:26026585. |
western blot analysis was carried out to detect key proteins involved in apoptosis. |
2016-04-06 |
2023-08-13 |
human |
| Jia-Dong Pang, Bao-Xiong Zhuang, Kaijin Mai, Ru-Fu Chen, Jie Wang, Li-Ming Zhan. Click modification of helical amylose by poly(l-lysine) dendrons for non-viral gene delivery. Materials science & engineering. C, Materials for biological applications. vol 49. 2016-04-05. PMID:25686975. |
western blot and cell apoptosis analyses confirmed its effectiveness for the delivery of plasmid pmscv-gfp-park2 to 293t cells. |
2016-04-05 |
2023-08-13 |
human |
| Danmin Huang, Wenjie Guo, Jing Gao, Jun Chen, Joshua Opeyemi Olatunj. Clinacanthus nutans (Burm. f.) Lindau Ethanol Extract Inhibits Hepatoma in Mice through Upregulation of the Immune Response. Molecules (Basel, Switzerland). vol 20. issue 9. 2016-04-05. PMID:26393569. |
western blot analysis of papr, caspase-3, bax, and bcl2 also showed that cn30 induced apoptosis in hepatoma cells. |
2016-04-05 |
2023-08-13 |
mouse |
| Qian Guo, Jiabin Guo, Rong Yang, Hui Peng, Jun Zhao, Li Li, Shuangqing Pen. Cyclovirobuxine D Attenuates Doxorubicin-Induced Cardiomyopathy by Suppression of Oxidative Damage and Mitochondrial Biogenesis Impairment. Oxidative medicine and cellular longevity. vol 2015. 2016-04-04. PMID:26075032. |
by using tunel assay and western blot analysis, we found that cvb-d pretreatment reduced dox-induced apoptosis of myocardial cells and mitochondrial cytochrome c release to cytosol. |
2016-04-04 |
2023-08-13 |
Not clear |
| Z P Feng, H C Deng, R Jiang, J Du, D Y Chen. Involvement of AP-1 in p38MAPK signaling pathway in osteoblast apoptosis induced by high glucose. Genetics and molecular research : GMR. vol 14. issue 2. 2016-04-01. PMID:25966080. |
apoptosis, protein levels of p38mapk, and activities of ap-1 in mc3t3-e1 osteoblasts were measured using tunel and flow cytometry, western blot analysis, and an electrophoretic mobility shift assay. |
2016-04-01 |
2023-08-13 |
Not clear |
| Meihui Chen, Yu Hou, Dingkun Li. Polydatin Protects Bone Marrow Stem Cells against Oxidative Injury: Involvement of Nrf 2/ARE Pathways. Stem cells international. vol 2016. 2016-03-29. PMID:27022401. |
hochest 33258, annexin v-pi, and western blot assay showed h2o2-induced apoptosis in bmscs, which was attenuated by polydatin. |
2016-03-29 |
2023-08-13 |
Not clear |
| Aurélien Raynaud, Nicolas Meunier, Adrien Acquistapace, Vincent Bombai. Chronic variable stress exposure in male Wistar rats affects the first step of olfactory detection. Behavioural brain research. vol 291. 2016-03-28. PMID:26003942. |
in addition we observed increased apoptosis markers in the olfactory mucosa using western blot. |
2016-03-28 |
2023-08-13 |
human |
| Kaouther Hadj Ayed Tka, Asma Mahfoudh Boussaid, Mohamed Amine Zaouali, Rym Kammoun, Mohamed Bejaoui, Sonia Ghoul Mazgar, Joan Rosello Catafau, Hassen Ben Abdenneb. Melatonin modulates endoplasmic reticulum stress and Akt/GSK3-beta signaling pathway in a rat model of renal warm ischemia reperfusion. Analytical cellular pathology (Amsterdam). vol 2015. 2016-03-25. PMID:26229743. |
in addition, western blot was performed to study er stress and its downstream apoptosis as well as phosphorylation of akt, gsk-3β, vdac, erk, and p38. |
2016-03-25 |
2023-08-13 |
rat |
| Xiang Chen, Jiake Feng, Zhijun Ge, Hong Chen, Weiliang Ding, Wenjiao Zhu, Xiaoyan Tang, Yanyu Chen, Yongfei Tan, Tieliang M. Effects of the JWA gene in the regulation of human breast cancer cells. Molecular medicine reports. vol 11. issue 5. 2016-03-24. PMID:25586271. |
following transfection with jwa‑small interfering (si)rna, the effect of jwa on apoptosis was assessed by western blot analysis, proliferation was determined using transwell chambers and cell migration and invasion were analyzed by transwell assay. |
2016-03-24 |
2023-08-13 |
human |
| Goutam Dey, Rashmi Bharti, Gunaseelan Dhanarajan, Subhasis Das, Kaushik Kumar Dey, B N Prashanth Kumar, Ramkrishna Sen, Mahitosh Manda. Marine lipopeptide Iturin A inhibits Akt mediated GSK3β and FoxO3a signaling and triggers apoptosis in breast cancer. Scientific reports. vol 5. 2016-03-24. PMID:25974307. |
proliferation of mda-mb-231 and mcf-7 breast cancer cells were significantly inhibited by iturin a and it induced apoptosis as confirmed by increased sub g1 populations, dna fragmentation, morphological changes and western blot analysis. |
2016-03-24 |
2023-08-13 |
human |
| Xiaodong Chen, Min Deng, Li Ma, Jiansheng Zhou, Yuzhou Xiao, Xinshe Zhou, Changchun Zhang, Min W. Inhibitory effects of forkhead box L1 gene on osteosarcoma growth through the induction of cell cycle arrest and apoptosis. Oncology reports. vol 34. issue 1. 2016-03-18. PMID:26062977. |
in addition, the expression of p21, p27, cytochrome c and caspase-3, which may be involved in the regulation of the cell cycle and apoptosis was examined using western blot analysis. |
2016-03-18 |
2023-08-13 |
Not clear |
| Junchao Huang, Chengchao Sun, Suqing Wang, Qiqiang He, Dejia L. microRNA miR-10b inhibition reduces cell proliferation and promotes apoptosis in non-small cell lung cancer (NSCLC) cells. Molecular bioSystems. vol 11. issue 7. 2016-03-16. PMID:25988292. |
real-time pcr was used to detect the expression levels of mir-10b in 75 nsclc patients' tissues and western blot was also used to analyze the expression level of genes correlated with apoptosis in nsclc cells. |
2016-03-16 |
2023-08-13 |
mouse |
| Wooyoung Jang, Hyun-Hee Park, Kyu-Yong Lee, Young Joo Lee, Hee-Tae Kim, Seong-Ho Ko. 1,25-dyhydroxyvitamin D3 attenuates L-DOPA-induced neurotoxicity in neural stem cells. Molecular neurobiology. vol 51. issue 2. 2016-03-14. PMID:25102940. |
we measured cell viability via the cell counting kit-8 (cck-8) and lactate dehydrogenase (ldh) assays and annexin v/pi staining followed by flow cytometry, cell proliferation using the brdu and colony-forming unit (cfu) assays, cell differentiation via immunocytochemistry, the levels of free radicals via 2',7'-dichlorodihydrofluorescein diacetate (dcfh-da) staining, apoptosis via dapi and tunel staining, and intracellular signaling protein expression via western blot. |
2016-03-14 |
2023-08-13 |
Not clear |
| Xiaoming Zhu, Yang Yang, Tao Han, Guowu Yin, Ping Gao, Yunfeng Ni, Xiaohua Su, Yuying Liu, Yuanqing Ya. Suppression of microRNA-18a expression inhibits invasion and promotes apoptosis of human trophoblast cells by targeting the estrogen receptor α gene. Molecular medicine reports. vol 12. issue 2. 2016-03-10. PMID:25955393. |
the effects of mir-18a on trophoblast cell invasion and apoptosis, and on the expression of estrogen receptor α (esrα) were analyzed using a transwell invasion assay, flow cytometry, reverse transcription-polymerase chain reaction, western blot analysis and a luciferase assay. |
2016-03-10 |
2023-08-13 |
human |
| Ming-Xue Piao, Ji-Wei Bai, Peng-Fei Zhang, Ya-Zhuo Zhan. PCSK9 regulates apoptosis in human neuroglioma u251 cells via mitochondrial signaling pathways. International journal of clinical and experimental pathology. vol 8. issue 3. 2016-03-10. PMID:26045785. |
in addition, western blot results showed that pcsk9 sirna promote apoptosis via activation of caspase-3 and down-regulation of the anti-apoptotic proteins, xiap and p-akt, while pcsk9 overexpression inhibited apoptosis. |
2016-03-10 |
2023-08-13 |
human |
| Cinzia Antognelli, Angela Gambelunghe, Giacomo Muzi, Vincenzo Nicola Tales. Peroxynitrite-mediated glyoxalase I epigenetic inhibition drives apoptosis in airway epithelial cells exposed to crystalline silica via a novel mechanism involving argpyrimidine-modified Hsp70, JNK, and NF-κB. Free radical biology & medicine. vol 84. 2016-03-04. PMID:25841781. |
apoptosis, by tdt-mediated dutp nick-end labeling assay, and transcript and protein levels or enzymatic activity, by quantitative real-time pcr, western blot, and spectrophotometric methods, respectively, were evaluated in human bronchial beas-2b cells exposed or not (control) to crystalline silica and also in experiments with appropriate inhibitors. |
2016-03-04 |
2023-08-13 |
human |
| Yin Sim Tor, Latifah Saiful Yazan, Jhi Biau Foo, Agustono Wibowo, Norsharina Ismail, Yoke Kqueen Cheah, Rasedee Abdullah, Maznah Ismail, Intan Safinar Ismail, Swee Keong Yea. Induction of Apoptosis in MCF-7 Cells via Oxidative Stress Generation, Mitochondria-Dependent and Caspase-Independent Pathway by Ethyl Acetate Extract of Dillenia suffruticosa and Its Chemical Profile. PloS one. vol 10. issue 6. 2016-03-04. PMID:26047480. |
the related molecular pathways involved in eads-induced apoptosis were determined by gexp multiplex system and western blot analysis. |
2016-03-04 |
2023-08-13 |
Not clear |
| Mingqun Li, Li Hon. Pseudolaric acid B exerts antitumor activity via suppression of the Akt signaling pathway in HeLa cervical cancer cells. Molecular medicine reports. vol 12. issue 2. 2016-03-03. PMID:25891953. |
in the present study, the effects of pab on the viability and apoptosis of hela cells were investigated by mtt assay, flow cytometric analysis of annexin v-fluorescein isothiocyanate/propidium iodide staining, rhodamine 123 staining and western blot analysis. |
2016-03-03 |
2023-08-13 |
human |